Page last updated: 2024-11-02

oxidopamine and Coronary Disease

oxidopamine has been researched along with Coronary Disease in 5 studies

Oxidopamine: A neurotransmitter analogue that depletes noradrenergic stores in nerve endings and induces a reduction of dopamine levels in the brain. Its mechanism of action is related to the production of cytolytic free-radicals.
oxidopamine : A benzenetriol that is phenethylamine in which the hydrogens at positions 2, 4, and 5 on the phenyl ring are replaced by hydroxy groups. It occurs naturally in human urine, but is also produced as a metabolite of the drug DOPA (used for the treatment of Parkinson's disease).

Coronary Disease: An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.

Research Excerpts

ExcerptRelevanceReference
"Arrhythmias were significantly more frequent during low flow (10% of control) than zero flow ischaemia and were most frequent during reperfusion following 30 minute ischaemia."1.27The deleterious effects of myocardial catecholamines on cellular electrophysiology and arrhythmias during ischaemia and reperfusion. ( Penny, WJ, 1984)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19904 (80.00)18.7374
1990's1 (20.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Culling, W2
Penny, WJ3
Lewis, MJ2
Middleton, K1
Sheridan, DJ2
Russell, JC1
Koeslag, DG1
Amy, RM1
Dolphin, PJ1
Matsuki, T1
Cohen, MV1
Holt, G1
Ayling, J1
Hearse, DJ1
Downey, JM1

Other Studies

5 other studies available for oxidopamine and Coronary Disease

ArticleYear
Effects of myocardial catecholamine depletion on cellular electrophysiology and arrhythmias during ischaemia and reperfusion.
    Cardiovascular research, 1984, Volume: 18, Issue:11

    Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Catecholamines; Coronary Disease; Glycogen; Guinea

1984
The deleterious effects of myocardial catecholamines on cellular electrophysiology and arrhythmias during ischaemia and reperfusion.
    European heart journal, 1984, Volume: 5, Issue:12

    Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Catecholamines; Coronary Disease; Electrophysiolog

1984
Myocardial disease and catecholamine metabolism in JCR:LA-corpulent rat.
    Experimental and molecular pathology, 1991, Volume: 54, Issue:1

    Topics: Animals; Aorta; Arteriosclerosis; Blood Glucose; Brain; Coronary Disease; Dopamine; Female; Hydroxyd

1991
Chronic whole body sympathectomy fails to protect ischemic rabbit hearts.
    The American journal of physiology, 1989, Volume: 256, Issue:5 Pt 2

    Topics: Animals; Collateral Circulation; Coronary Circulation; Coronary Disease; Female; Heart Ventricles; H

1989
Antiarrhythmic and electrophysiological effects of alpha adrenoceptor blockade during myocardial ischaemia and reperfusion in isolated guinea-pig heart.
    Journal of molecular and cellular cardiology, 1985, Volume: 17, Issue:4

    Topics: Adrenergic alpha-Antagonists; Animals; Arrhythmias, Cardiac; Catecholamines; Coronary Disease; Elect

1985