Page last updated: 2024-11-02

oxidopamine and Constipation

oxidopamine has been researched along with Constipation in 2 studies

Oxidopamine: A neurotransmitter analogue that depletes noradrenergic stores in nerve endings and induces a reduction of dopamine levels in the brain. Its mechanism of action is related to the production of cytolytic free-radicals.
oxidopamine : A benzenetriol that is phenethylamine in which the hydrogens at positions 2, 4, and 5 on the phenyl ring are replaced by hydroxy groups. It occurs naturally in human urine, but is also produced as a metabolite of the drug DOPA (used for the treatment of Parkinson's disease).

Constipation: Infrequent or difficult evacuation of FECES. These symptoms are associated with a variety of causes, including low DIETARY FIBER intake, emotional or nervous disturbances, systemic and structural disorders, drug-induced aggravation, and infections.

Research Excerpts

ExcerptRelevanceReference
"Constipation is extremely common in patients with Parkinson's disease (PD) and has been described in PD animal models."1.42Response of colonic motility to dopaminergic stimulation is subverted in rats with nigrostriatal lesion: relevance to gastrointestinal dysfunctions in Parkinson's disease. ( Ambrosi, G; Balestra, B; Blandini, F; Bonizzi, A; Cerri, S; Ferrigno, A; Ghezzi, C; Levandis, G; Pastoris, O; Rizzo, V; Siani, F; Vairetti, M; Vicini, R, 2015)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Karasawa, H1
Pietra, C1
Giuliano, C1
Garcia-Rubio, S1
Xu, X1
Yakabi, S1
Taché, Y1
Wang, L1
Levandis, G1
Balestra, B1
Siani, F1
Rizzo, V1
Ghezzi, C1
Ambrosi, G1
Cerri, S1
Bonizzi, A1
Vicini, R1
Vairetti, M1
Ferrigno, A1
Pastoris, O1
Blandini, F1

Other Studies

2 other studies available for oxidopamine and Constipation

ArticleYear
New ghrelin agonist, HM01 alleviates constipation and L-dopa-delayed gastric emptying in 6-hydroxydopamine rat model of Parkinson's disease.
    Neurogastroenterology and motility, 2014, Volume: 26, Issue:12

    Topics: Animals; Antiparkinson Agents; Brain; Constipation; Gastrointestinal Transit; Ghrelin; Immunohistoch

2014
Response of colonic motility to dopaminergic stimulation is subverted in rats with nigrostriatal lesion: relevance to gastrointestinal dysfunctions in Parkinson's disease.
    Neurogastroenterology and motility, 2015, Volume: 27, Issue:12

    Topics: Animals; Chromatography, High Pressure Liquid; Colon; Constipation; Disease Models, Animal; Dopamine

2015