Page last updated: 2024-11-02

oxidopamine and Colitis

oxidopamine has been researched along with Colitis in 3 studies

Oxidopamine: A neurotransmitter analogue that depletes noradrenergic stores in nerve endings and induces a reduction of dopamine levels in the brain. Its mechanism of action is related to the production of cytolytic free-radicals.
oxidopamine : A benzenetriol that is phenethylamine in which the hydrogens at positions 2, 4, and 5 on the phenyl ring are replaced by hydroxy groups. It occurs naturally in human urine, but is also produced as a metabolite of the drug DOPA (used for the treatment of Parkinson's disease).

Colitis: Inflammation of the COLON section of the large intestine (INTESTINE, LARGE), usually with symptoms such as DIARRHEA (often with blood and mucus), ABDOMINAL PAIN, and FEVER.

Research Excerpts

ExcerptRelevanceReference
"We assessed the effects of primary afferent nerve ablation (systemic treatment with capsaicin during adult or neonatal periods), primary afferent nerve activation (intracolonic capsaicin), and sympathectomy [6-hydroxydopamine (6-OHDA)] on the development of colitis induced by 2,4,6-trinitrobenzenesulfonic acid (TNBS) in rats."3.69Effects of chemical sympathectomy and sensory nerve ablation on experimental colitis in the rat. ( McCafferty, DM; Sharkey, KA; Wallace, JL, 1997)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's1 (33.33)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Willemze, RA1
Welting, O1
van Hamersveld, P1
Verseijden, C1
Nijhuis, LE1
Hilbers, FW1
Meijer, SL1
Heesters, BA1
Folgering, JHA1
Darwinkel, H1
Blancou, P1
Vervoordeldonk, MJ1
Seppen, J1
Heinsbroek, SEM1
de Jonge, WJ1
McCafferty, DM1
Wallace, JL1
Sharkey, KA1
Kalmari, J1
Niissalo, S1
Konttinen, YT1
Pertovaara, A1

Other Studies

3 other studies available for oxidopamine and Colitis

ArticleYear
Loss of intestinal sympathetic innervation elicits an innate immune driven colitis.
    Molecular medicine (Cambridge, Mass.), 2019, 01-07, Volume: 25, Issue:1

    Topics: Adrenergic beta-2 Receptor Agonists; Albuterol; Animals; Cells, Cultured; Colitis; Colon; Cytokines;

2019
Effects of chemical sympathectomy and sensory nerve ablation on experimental colitis in the rat.
    The American journal of physiology, 1997, Volume: 272, Issue:2 Pt 1

    Topics: Administration, Topical; Animals; Capsaicin; Colitis; Colon; Denervation; Female; Injections; Lidoca

1997
Modulation of visceral nociceptive responses of rat spinal dorsal horn neurons by sympathectomy.
    Neuroreport, 2001, Mar-26, Volume: 12, Issue:4

    Topics: Animals; Colitis; Colon; Hyperalgesia; Irritants; Male; Nociceptors; Oxidopamine; Posterior Horn Cel

2001