oxidopamine has been researched along with Cognitive Decline in 6 studies
Oxidopamine: A neurotransmitter analogue that depletes noradrenergic stores in nerve endings and induces a reduction of dopamine levels in the brain. Its mechanism of action is related to the production of cytolytic free-radicals.
oxidopamine : A benzenetriol that is phenethylamine in which the hydrogens at positions 2, 4, and 5 on the phenyl ring are replaced by hydroxy groups. It occurs naturally in human urine, but is also produced as a metabolite of the drug DOPA (used for the treatment of Parkinson's disease).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cognitive decline is a common clinical symptom in Parkinson's disease (PD) patients." | 1.62 | Fluoxetine tunes the abnormal hippocampal oscillations in association with cognitive impairments in 6-OHDA lesioned rats. ( Feng, H; Liu, W; Zhang, R; Zhu, H, 2021) |
| "One such symptom is mild cognitive impairment (PD-MCI), which is comprised of deficits in executive function such as working memory, attention, cognitive flexibility, and spatial memory." | 1.51 | Limitations of the rat medial forebrain lesion model to study prefrontal cortex mediated cognitive tasks in Parkinson's disease. ( King, KM; Kortagere, S; Marshall, CA, 2019) |
| "Manganese (Mn) is an essential nutrient especially during development, but Mn overexposure (MnOE) produces long-term cognitive deficits." | 1.51 | Effects of Preweaning Manganese in Combination with Adult Striatal Dopamine Lesions on Monoamines, BDNF, TrkB, and Cognitive Function in Sprague-Dawley Rats. ( Bailey, RA; Gutierrez, A; Hemmerle, AM; Hufgard, JR; Kyser, TL; Seroogy, KB; Vorhees, CV; Williams, MT, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 3 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pan, S | 3 |
| Wang, L | 3 |
| Wang, Y | 3 |
| Dong, X | 3 |
| Liu, Y | 3 |
| Zhou, A | 3 |
| Xing, H | 3 |
| Wang, Z | 1 |
| Flores, I | 1 |
| Donahue, EK | 1 |
| Lundquist, AJ | 1 |
| Guo, Y | 1 |
| Petzinger, GM | 1 |
| Jakowec, MW | 1 |
| Holschneider, DP | 1 |
| Liu, W | 1 |
| Zhang, R | 1 |
| Feng, H | 1 |
| Zhu, H | 1 |
| Haghparast, E | 1 |
| Esmaeili-Mahani, S | 1 |
| Abbasnejad, M | 1 |
| Sheibani, V | 1 |
| Marshall, CA | 1 |
| King, KM | 1 |
| Kortagere, S | 1 |
| Bailey, RA | 1 |
| Gutierrez, A | 1 |
| Kyser, TL | 1 |
| Hemmerle, AM | 1 |
| Hufgard, JR | 1 |
| Seroogy, KB | 1 |
| Vorhees, CV | 1 |
| Williams, MT | 1 |
6 other studies available for oxidopamine and Cognitive Decline
| Article | Year |
|---|---|
Transplantation of ERK gene-modified bone marrow mesenchymal stem cells ameliorates cognitive deficits in a 6-hydroxydopamine rat model of Parkinson's disease.
Topics: Animals; Bone Marrow Cells; Bone Marrow Transplantation; Cognition; Cognitive Dysfunction; Mesenchym | 2023 |
Transplantation of ERK gene-modified bone marrow mesenchymal stem cells ameliorates cognitive deficits in a 6-hydroxydopamine rat model of Parkinson's disease.
Topics: Animals; Bone Marrow Cells; Bone Marrow Transplantation; Cognition; Cognitive Dysfunction; Mesenchym | 2023 |
Transplantation of ERK gene-modified bone marrow mesenchymal stem cells ameliorates cognitive deficits in a 6-hydroxydopamine rat model of Parkinson's disease.
Topics: Animals; Bone Marrow Cells; Bone Marrow Transplantation; Cognition; Cognitive Dysfunction; Mesenchym | 2023 |
Transplantation of ERK gene-modified bone marrow mesenchymal stem cells ameliorates cognitive deficits in a 6-hydroxydopamine rat model of Parkinson's disease.
Topics: Animals; Bone Marrow Cells; Bone Marrow Transplantation; Cognition; Cognitive Dysfunction; Mesenchym | 2023 |
Cognitive flexibility deficits in rats with dorsomedial striatal 6-hydroxydopamine lesions tested using a three-choice serial reaction time task with reversal learning.
Topics: Animals; Choice Behavior; Cognition; Cognitive Dysfunction; Corpus Striatum; Discrimination, Psychol | 2020 |
Fluoxetine tunes the abnormal hippocampal oscillations in association with cognitive impairments in 6-OHDA lesioned rats.
Topics: Adrenergic Agents; Animals; Behavior, Animal; Brain Waves; Cognitive Dysfunction; Disease Models, An | 2021 |
Apelin-13 ameliorates cognitive impairments in 6-hydroxydopamine-induced substantia nigra lesion in rats.
Topics: Animals; Behavior, Animal; Cognitive Dysfunction; Intercellular Signaling Peptides and Proteins; Mal | 2018 |
Limitations of the rat medial forebrain lesion model to study prefrontal cortex mediated cognitive tasks in Parkinson's disease.
Topics: Animals; Brain; Cognition; Cognitive Dysfunction; Disease Models, Animal; Dopamine; Dopaminergic Neu | 2019 |
Effects of Preweaning Manganese in Combination with Adult Striatal Dopamine Lesions on Monoamines, BDNF, TrkB, and Cognitive Function in Sprague-Dawley Rats.
Topics: Animals; Brain; Brain-Derived Neurotrophic Factor; Cognition; Cognitive Dysfunction; Dopamine; Femal | 2019 |