oxidopamine has been researched along with Channelopathies in 1 studies
Oxidopamine: A neurotransmitter analogue that depletes noradrenergic stores in nerve endings and induces a reduction of dopamine levels in the brain. Its mechanism of action is related to the production of cytolytic free-radicals.
oxidopamine : A benzenetriol that is phenethylamine in which the hydrogens at positions 2, 4, and 5 on the phenyl ring are replaced by hydroxy groups. It occurs naturally in human urine, but is also produced as a metabolite of the drug DOPA (used for the treatment of Parkinson's disease).
Channelopathies: A variety of neuromuscular conditions resulting from MUTATIONS in ION CHANNELS manifesting as episodes of EPILEPSY; HEADACHE DISORDERS; and DYSKINESIAS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Parkinson's disease is a common neurodegenerative disorder characterized by a profound motor disability that is traceable to the emergence of synchronous, rhythmic spiking in neurons of the external segment of the globus pallidus (GPe)." | 1.37 | HCN channelopathy in external globus pallidus neurons in models of Parkinson's disease. ( Chan, CS; Chetkovich, DM; Fleming, SM; Gertler, TS; Glajch, KE; Goldberg, AB; Guzman, JN; Kita, H; Lewis, AS; Mercer, JN; Osten, P; Shigemoto, R; Surmeier, DJ; Tkatch, T, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chan, CS | 1 |
| Glajch, KE | 1 |
| Gertler, TS | 1 |
| Guzman, JN | 1 |
| Mercer, JN | 1 |
| Lewis, AS | 1 |
| Goldberg, AB | 1 |
| Tkatch, T | 1 |
| Shigemoto, R | 1 |
| Fleming, SM | 1 |
| Chetkovich, DM | 1 |
| Osten, P | 1 |
| Kita, H | 1 |
| Surmeier, DJ | 1 |
1 other study available for oxidopamine and Channelopathies
| Article | Year |
|---|---|
HCN channelopathy in external globus pallidus neurons in models of Parkinson's disease.
Topics: Animals; Calcium; Channelopathies; Dependovirus; Disease Models, Animal; Dopamine; Down-Regulation; | 2011 |