oxidopamine has been researched along with Catatonic Rigidity in 7 studies
Oxidopamine: A neurotransmitter analogue that depletes noradrenergic stores in nerve endings and induces a reduction of dopamine levels in the brain. Its mechanism of action is related to the production of cytolytic free-radicals.
oxidopamine : A benzenetriol that is phenethylamine in which the hydrogens at positions 2, 4, and 5 on the phenyl ring are replaced by hydroxy groups. It occurs naturally in human urine, but is also produced as a metabolite of the drug DOPA (used for the treatment of Parkinson's disease).
| Excerpt | Relevance | Reference |
|---|---|---|
| "It has previously been reported that intracerebroventricular administration of neurotensin (30 micrograms) reduced muscular rigidity and tremors, induced by a neurochemical lesion with 6-hydroxydopamine in the posterolateral hypothalamus of rats." | 7.68 | Structure-activity studies of neurotensin on muscular rigidity and tremors induced by 6-hydroxydopamine lesions in the posterolateral hypothalamus of the rat. ( Jolicoeur, FB; Rivest, R; St-Pierre, S, 1991) |
| " Moreover, XE991 decreased apomorphine (APO)-induced contralateral rotations, enhanced balance and coordination, and attenuated muscle rigidity in 6-OHDA-treated rats." | 3.88 | The Kv7/KCNQ channel blocker XE991 protects nigral dopaminergic neurons in the 6-hydroxydopamine rat model of Parkinson's disease. ( Chen, X; Jia, L; Liu, H; Shi, L; Xie, J, 2018) |
| "It has previously been reported that intracerebroventricular administration of neurotensin (30 micrograms) reduced muscular rigidity and tremors, induced by a neurochemical lesion with 6-hydroxydopamine in the posterolateral hypothalamus of rats." | 3.68 | Structure-activity studies of neurotensin on muscular rigidity and tremors induced by 6-hydroxydopamine lesions in the posterolateral hypothalamus of the rat. ( Jolicoeur, FB; Rivest, R; St-Pierre, S, 1991) |
| "The loss of this action would cause muscular rigidity and motor asymmetry." | 1.29 | Appearance of EMG activity and motor asymmetry after unilateral lesions of the dopaminergic innervation to the subthalamic nucleus in the rat. ( Aceves, J; Flores, G; Rosales, MG; Sierra, A; Valencia, J, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 4 (57.14) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, H | 1 |
| Jia, L | 1 |
| Chen, X | 1 |
| Shi, L | 1 |
| Xie, J | 1 |
| Lin, JW | 1 |
| Shih, CM | 1 |
| Chen, YC | 1 |
| Lin, CM | 1 |
| Tsai, JT | 1 |
| Chiang, YH | 1 |
| Shih, R | 1 |
| Chiu, PL | 1 |
| Hung, KS | 1 |
| Yeh, YS | 1 |
| Wei, L | 1 |
| Chiu, WT | 1 |
| Yang, LY | 1 |
| Carey, RJ | 1 |
| Flores, G | 1 |
| Valencia, J | 1 |
| Rosales, MG | 1 |
| Sierra, A | 1 |
| Aceves, J | 1 |
| Lindner, MD | 1 |
| Cain, CK | 1 |
| Plone, MA | 1 |
| Frydel, BR | 1 |
| Blaney, TJ | 1 |
| Emerich, DF | 1 |
| Hoane, MR | 1 |
| Jolicoeur, FB | 2 |
| Rivest, R | 2 |
| Drumheller, A | 1 |
| St-Pierre, S | 1 |
7 other studies available for oxidopamine and Catatonic Rigidity
| Article | Year |
|---|---|
The Kv7/KCNQ channel blocker XE991 protects nigral dopaminergic neurons in the 6-hydroxydopamine rat model of Parkinson's disease.
Topics: Animals; Anthracenes; Apomorphine; Corpus Striatum; Dopamine; Dopamine Agonists; Dopaminergic Neuron | 2018 |
Biochemical alteration in cerebrospinal fluid precedes behavioral deficits in Parkinsonian rats induced by 6-hydroxydopamine.
Topics: Animals; Biomarkers; Cell Count; Cell Death; Disease Models, Animal; Dopamine; Homovanillic Acid; Hy | 2009 |
Differential effects of limbic versus striatal dopamine loss on motoric function.
Topics: Animals; Catalepsy; Corpus Striatum; Dextroamphetamine; Dopamine; Humans; Hydroxydopamines; Limbic S | 1983 |
Appearance of EMG activity and motor asymmetry after unilateral lesions of the dopaminergic innervation to the subthalamic nucleus in the rat.
Topics: Animals; Bicuculline; Dopamine; Electromyography; gamma-Aminobutyric Acid; Male; Methamphetamine; Mo | 1993 |
Incomplete nigrostriatal dopaminergic cell loss and partial reductions in striatal dopamine produce akinesia, rigidity, tremor and cognitive deficits in middle-aged rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Age Factors; Animals; Brain Mapping; Corpus Striatum; Dementia; Dopa | 1999 |
Hypokinesia, rigidity, and tremor induced by hypothalamic 6-OHDA lesions in the rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Dopamine; Dyskinesia, Drug-Induced; Homovanillic Aci | 1991 |
Structure-activity studies of neurotensin on muscular rigidity and tremors induced by 6-hydroxydopamine lesions in the posterolateral hypothalamus of the rat.
Topics: Animals; Cerebral Ventricles; Disease Models, Animal; Dose-Response Relationship, Drug; Hydroxydopam | 1991 |