Page last updated: 2024-11-02

oxidopamine and Brain Ischemia

oxidopamine has been researched along with Brain Ischemia in 14 studies

Oxidopamine: A neurotransmitter analogue that depletes noradrenergic stores in nerve endings and induces a reduction of dopamine levels in the brain. Its mechanism of action is related to the production of cytolytic free-radicals.
oxidopamine : A benzenetriol that is phenethylamine in which the hydrogens at positions 2, 4, and 5 on the phenyl ring are replaced by hydroxy groups. It occurs naturally in human urine, but is also produced as a metabolite of the drug DOPA (used for the treatment of Parkinson's disease).

Brain Ischemia: Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19901 (7.14)18.7374
1990's4 (28.57)18.2507
2000's5 (35.71)29.6817
2010's3 (21.43)24.3611
2020's1 (7.14)2.80

Authors

AuthorsStudies
Fan, Y1
Li, M1
Wu, C1
Wu, Y1
Han, J1
Wu, P1
Huang, Z1
Wang, Q1
Zhao, L1
Chen, D1
Zhu, M1
Romero, A1
Parada, E1
González-Lafuente, L1
Farré-Alins, V1
Ramos, E1
Cacabelos, R1
Egea, J1
Tiurenkov, IN1
Volotova, EV1
Kurkin, DV1
Bakulin, DA1
Logvinov, IO1
Antipova, TA1
Shah, A1
Garzon-Muvdi, T1
Mahajan, R1
Duenas, VJ1
Quiñones-Hinojosa, A1
Pang, ZP1
Ling, GY1
Gajendiran, M1
Xu, ZC1
Saulle, E1
Centonze, D1
Martín, AB1
Moratalla, R1
Bernardi, G1
Calabresi, P1
Wang, Y1
Chang, CF1
Morales, M1
Chiang, YH1
Harvey, BK1
Su, TP1
Tsao, LI1
Chen, S1
Thiemermann, C1
d'Aldin, C1
Eybalin, M1
Puel, JL1
Charachon, G1
Ladrech, S1
Renard, N1
Pujol, R1
Lin, MT1
Kao, TY1
Chio, CC1
Jin, YT1
Schallert, T1
Fleming, SM1
Leasure, JL1
Tillerson, JL1
Bland, ST1
Sun, YF1
Tang, FM1
Ding, YM1
Chen, YT1
Zhang, GY1
Jin, GZ1
Buisson, A1
Callebert, J1
Mathieu, E1
Plotkine, M1
Boulu, RG1
Kobayashi, H1
Hayashi, M1
Handa, Y1
Noguchi, Y1
Kawano, H1
Kabuto, M1
Globus, MY1
Ginsberg, MD1
Harik, SI1
Busto, R1
Dietrich, WD1

Reviews

1 review available for oxidopamine and Brain Ischemia

ArticleYear
Animal models of neurological disease.
    Advances in experimental medicine and biology, 2010, Volume: 671

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Adrenergic Agents; Amyloid beta-Protein Precursor; Ani

2010

Other Studies

13 other studies available for oxidopamine and Brain Ischemia

ArticleYear
Chronic Cerebral Hypoperfusion Aggravates Parkinson's Disease Dementia-Like Symptoms and Pathology in 6-OHDA-Lesioned Rat through Interfering with Sphingolipid Metabolism.
    Oxidative medicine and cellular longevity, 2022, Volume: 2022

    Topics: Alzheimer Disease; Animals; Brain Ischemia; Dementia; Disease Models, Animal; Lipid Metabolism; Male

2022
Neuroprotective effects of E-PodoFavalin-15999 (Atremorine®).
    CNS neuroscience & therapeutics, 2017, Volume: 23, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Brain Ischemia; Cell Line, Tumor; Cell Survival; D

2017
[Neuroprotective effect of neuroglutam under conditions of activated free radical oxidation].
    Eksperimental'naia i klinicheskaia farmakologiia, 2014, Volume: 77, Issue:8

    Topics: Animals; Brain Ischemia; Cell Line, Tumor; Erythrocytes; Free Radicals; Glutamic Acid; Hemolysis; Hu

2014
Asymmetrical changes of excitatory synaptic transmission in dopamine-denervated striatum after transient forebrain ischemia.
    Neuroscience, 2002, Volume: 114, Issue:2

    Topics: Animals; Brain Ischemia; Dopamine; Electric Stimulation; Excitatory Postsynaptic Potentials; Functio

2002
Endogenous dopamine amplifies ischemic long-term potentiation via D1 receptors.
    Stroke, 2002, Volume: 33, Issue:12

    Topics: Animals; Benzazepines; Brain Ischemia; Corpus Striatum; Cyclic AMP; Cyclic AMP-Dependent Protein Kin

2002
Diadenosine tetraphosphate protects against injuries induced by ischemia and 6-hydroxydopamine in rat brain.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2003, Aug-27, Volume: 23, Issue:21

    Topics: Animals; Apoptosis; Blood Pressure; Brain Ischemia; Cell Hypoxia; Cells, Cultured; Cerebral Cortex;

2003
Synaptic connections and putative functions of the dopaminergic innervation of the guinea pig cochlea.
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 1995, Volume: 252, Issue:5

    Topics: Animals; Brain Ischemia; Cochlea; Dopamine Agonists; Ear, Inner; Guinea Pigs; Hair Cells, Auditory;

1995
Dopamine depletion protects striatal neurons from heatstroke-induced ischemia and cell death in rats.
    The American journal of physiology, 1995, Volume: 269, Issue:2 Pt 2

    Topics: Animals; Brain Ischemia; Corpus Striatum; Dopamine; Heat Exhaustion; Male; Neurons; Oxidopamine; Rat

1995
CNS plasticity and assessment of forelimb sensorimotor outcome in unilateral rat models of stroke, cortical ablation, parkinsonism and spinal cord injury.
    Neuropharmacology, 2000, Mar-03, Volume: 39, Issue:5

    Topics: Animals; Behavior, Animal; Bone Morphogenetic Protein 7; Bone Morphogenetic Proteins; Brain Ischemia

2000
Effect of dopamine depletion on DARPP-32 protein in ischemic rat striatum.
    Acta pharmacologica Sinica, 2001, Volume: 22, Issue:3

    Topics: Animals; Brain Ischemia; Corpus Striatum; Dopamine; Dopamine and cAMP-Regulated Phosphoprotein 32; M

2001
Striatal protection induced by lesioning the substantia nigra of rats subjected to focal ischemia.
    Journal of neurochemistry, 1992, Volume: 59, Issue:3

    Topics: Animals; Aspartic Acid; Brain Ischemia; Cerebral Infarction; Corpus Striatum; Dopamine; Extracellula

1992
Role of adrenergic activity in ischemic brain edema.
    Advances in neurology, 1990, Volume: 52

    Topics: Animals; Blood-Brain Barrier; Brain Edema; Brain Ischemia; Cerebral Arteries; Cerebral Cortex; Cereb

1990
Role of dopamine in ischemic striatal injury: metabolic evidence.
    Neurology, 1987, Volume: 37, Issue:11

    Topics: Animals; Blood Glucose; Blood Pressure; Brain Ischemia; Cerebrovascular Circulation; Corpus Striatum

1987