Page last updated: 2024-11-02

oxidopamine and Brain Disorders

oxidopamine has been researched along with Brain Disorders in 61 studies

Oxidopamine: A neurotransmitter analogue that depletes noradrenergic stores in nerve endings and induces a reduction of dopamine levels in the brain. Its mechanism of action is related to the production of cytolytic free-radicals.
oxidopamine : A benzenetriol that is phenethylamine in which the hydrogens at positions 2, 4, and 5 on the phenyl ring are replaced by hydroxy groups. It occurs naturally in human urine, but is also produced as a metabolite of the drug DOPA (used for the treatment of Parkinson's disease).

Research Excerpts

ExcerptRelevanceReference
"The work shows the effects of caffeine after the intrastriatal injection of 6-OHDA in rats, considered as a model of Parkinson disease (PD)."3.73Neuroprotective effects of caffeine in the model of 6-hydroxydopamine lesion in rats. ( Aguiar, LM; Cunha, GM; Freitas, RM; Macêdo, DS; Nobre, HV; Oliveira, AA; Sousa, FC; Vasconcelos, SM; Viana, GS, 2006)
" Interestingly, firing rates of neurons in all groups decreased by fivefold or greater under urethane anesthesia, although the relative firing rates between hemispheres were unchanged."3.70Multiple single-unit recordings in the striatum of freely moving animals: effects of apomorphine and D-amphetamine in normal and unilateral 6-hydroxydopamine-lesioned rats. ( Gerhardt, GA; Kish, LJ; Palmer, MR, 1999)
"Levodopa, the major treatment for patients with Parkinson's disease, has been shown to induce a variety of compensatory effects, including facilitation of sprouting by dopaminergic neurons, in experimental animals with lesions leading to denervation of the striatum."1.32Differential gene expression induced by chronic levodopa treatment in the striatum of rats with lesions of the nigrostriatal system. ( Delfino, MA; Ferrario, JE; Gershanik, O; Mourlevat, S; Murer, MG; Raisman-Vozari, R; Ruberg, M; Stefano, A; Taravini, IR, 2004)
"Pergolide was more potent than bromocriptine or lergotrile."1.26Pergolide-induced circling in rats with 6-hydroxydopamine lesions in the nigrostriatal pathway. ( Duvoisin, RC; Heikkila, RE; Manzino, L, 1982)

Research

Studies (61)

TimeframeStudies, this research(%)All Research%
pre-199025 (40.98)18.7374
1990's19 (31.15)18.2507
2000's15 (24.59)29.6817
2010's2 (3.28)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
He, X1
Yuan, W1
Li, Z1
Feng, J1
Li, X1
Chen, Z1
Tang, J1
Liu, C1
Zou, P1
Huang, H1
Tan, C1
Yu, H1
Androutsellis-Theotokis, A1
Rueger, MA1
Mkhikian, H1
Korb, E1
McKay, RD1
Jaworski, RL1
Blair, ML1
Moroz, IA1
Peciña, S1
Schallert, T1
Stewart, J1
Ferrario, JE1
Taravini, IR1
Mourlevat, S1
Stefano, A1
Delfino, MA1
Raisman-Vozari, R1
Murer, MG1
Ruberg, M1
Gershanik, O1
Kim, MS1
Lee, JI1
Lee, WY1
Kim, SE1
Grothe, C1
Timmer, M1
Scholz, T1
Winkler, C1
Nikkhah, G1
Claus, P1
Itoh, N1
Arenas, E2
Courtière, A1
Hardouin, J1
Locatelli, V1
Turle-Lorenzo, N1
Amalric, M2
Vidal, F1
Hasbroucq, T1
Aguiar, LM1
Nobre, HV1
Macêdo, DS1
Oliveira, AA1
Freitas, RM1
Vasconcelos, SM1
Cunha, GM1
Sousa, FC1
Viana, GS1
Parish, CL1
Beljajeva, A1
Simon, A1
Nakai, K1
Kasamatsu, T1
Duvoisin, RC1
Heikkila, RE1
Manzino, L1
Pritzel, M1
Huston, JP2
Sarter, M1
Kojima, H1
Gorio, A1
Janigro, D1
Jonsson, G1
Sumners, C1
Woodruff, GN1
Poat, JA1
Hossain, MA2
Weiner, N2
Pei, G1
Ebendal, T1
Boldry, RC1
Chase, TN1
Engber, TM1
Schwarting, RK1
Goldenberg, R1
Steiner, H1
Fornaguera, J1
Annett, LE1
Martel, FL1
Rogers, DC1
Ridley, RM1
Baker, HF1
Dunnett, SB2
Kondoh, T1
Low, WC2
Sørensen, JC1
Ostergaard, K1
Zimmer, J1
Zhu, YS1
Jones, SB1
Burke, RE1
Franklin, SO1
Inturrisi, CE1
Poncelet, M1
Gueudet, C1
Gully, D1
Soubrié, P1
Le Fur, G1
Ouagazzal, A1
Nieoullon, A2
Efange, SM1
Langason, RB1
Khare, AB1
Fenu, S1
Pinna, A1
Ongini, E1
Morelli, M1
Araki, T1
Tanji, H1
Kato, H1
Itoyama, Y1
Kish, LJ1
Palmer, MR1
Gerhardt, GA1
Laprade, N1
Soghomonian, JJ1
Joseph, MH1
Peters, SL1
Moran, PM1
Grigoryan, GA1
Young, AM1
Gray, JA1
Ni, ZG1
Gao, DM1
Benabid, AL1
Benazzouz, A1
Vaudano, E1
Rosenblad, C1
Björklund, A3
Xia, XG1
Schmidt, N1
Teismann, P1
Ferger, B1
Schulz, JB1
Zahran, AR1
Simmerman, N1
Carrier, S1
Vachon, P1
Asanuma, M1
Miyazaki, I1
Higashi, Y1
Tanaka, K1
Haque, ME1
Fujita, N1
Ogawa, N1
Castañeda, E1
Whishaw, IQ2
Robinson, TE1
Ozaki, A1
Ikegami, A1
Yoshidomi, M1
Yamashita, A1
Sukamoto, T1
Meloni, R1
Gale, K1
Levin, BE1
Battisti, WP1
Murray, M1
Mahalik, TJ1
Finger, TE1
Stromberg, I1
Olson, L1
Jones, GH1
Isacson, O2
Apicella, P1
Legallet, E1
Trouche, E1
Hyttel, J1
Arnt, J1
Gerfen, CR1
Baimbridge, KG1
Thibault, J1
Jenner, P1
Boyce, S1
Marsden, CD1
Robain, O1
Lanfumey, L1
Adrien, J1
Farkas, E1
Nishino, H2
Ono, T2
Takahashi, J2
Kimura, M2
Shiosaka, S2
Yamasaki, H1
Hatanaka, H1
Tohyama, M2
Orr, WB1
Gardiner, TW1
Stricker, EM2
Zigmond, MJ2
Berger, TW2
Nisenbaum, ES1
Choulli, K1
Herman, JP1
Rivet, JM1
Simon, H1
Le Moal, M1
Fibiger, HC1
LePiane, FG1
Jakubovic, A1
Phillips, AG1
Gramsbergen, JB1
Veenma-van der Duin, L1
Loopuijt, L1
Paans, AM1
Vaalburg, W1
Korf, J1
Lindvall, O1
Auer, RN1
Siesjö, BK1
Shimizu, K1
Tsuda, N1
Okamoto, Y1
Matsui, Y1
Miyao, Y1
Tamura, K1
Yamada, M1
Nakatani, S1
Ikeda, T1
Mogami, H1
Brundin, P1
Barbin, G1
Mallat, M1
Chamak, B1
Prochiantz, A1
Gage, FH2
Pellis, SM1
Chen, YC1
Chesire, RM1
Teitelbaum, P1

Reviews

3 reviews available for oxidopamine and Brain Disorders

ArticleYear
Signaling pathways controlling neural stem cells slow progressive brain disease.
    Cold Spring Harbor symposia on quantitative biology, 2008, Volume: 73

    Topics: Adult; Animals; Basic Helix-Loop-Helix Transcription Factors; Brain Diseases; Cell Survival; Dopamin

2008
Receptor changes during chronic dopaminergic stimulation.
    Journal of neural transmission. Supplementum, 1988, Volume: 27

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Behavior, Animal; Brain Diseases; Bromocripti

1988
Neural grafting in animal models of neurodegenerative diseases.
    Annals of the New York Academy of Sciences, 1985, Volume: 457

    Topics: Aging; Animals; Behavior, Animal; Brain; Brain Diseases; Choline; Corpus Striatum; Denervation; Dise

1985

Other Studies

58 other studies available for oxidopamine and Brain Disorders

ArticleYear
An autophagic mechanism is involved in the 6-hydroxydopamine-induced neurotoxicity in vivo.
    Toxicology letters, 2017, Oct-05, Volume: 280

    Topics: AMP-Activated Protein Kinases; Animals; Autophagy; Behavior, Animal; Brain Diseases; Gene Expression

2017
Synthesis and biological evaluation of 10-(11) C-dihydrotetrabenazine as a vesicular monoamine transporter 2 radioligand.
    Archiv der Pharmazie, 2014, Volume: 347, Issue:5

    Topics: Animals; Brain Diseases; Carbon Radioisotopes; Cerebellum; Corpus Striatum; Molecular Structure; Oxi

2014
Lesions of the dorsal noradrenergic bundle augment the renin response to blood loss but do not alter hypothalamic Fos expression.
    Brain research bulletin, 2004, Jul-15, Volume: 63, Issue:6

    Topics: Adrenergic Agents; Analysis of Variance; Animals; Blood Pressure; Brain Diseases; Cell Count; Heart

2004
Sparing of behavior and basal extracellular dopamine after 6-hydroxydopamine lesions of the nigrostriatal pathway in rats exposed to a prelesion sensitizing regimen of amphetamine.
    Experimental neurology, 2004, Volume: 189, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Agents; Amphetamine; Analysis of Variance; Animals; Behav

2004
Differential gene expression induced by chronic levodopa treatment in the striatum of rats with lesions of the nigrostriatal system.
    Journal of neurochemistry, 2004, Volume: 90, Issue:6

    Topics: Animals; Antiparkinson Agents; Behavior, Animal; Brain Diseases; Calmodulin; Carrier Proteins; Cell

2004
Neuroprotective effect of Ginkgo biloba L. extract in a rat model of Parkinson's disease.
    Phytotherapy research : PTR, 2004, Volume: 18, Issue:8

    Topics: Animals; Brain Diseases; Disease Models, Animal; Gait; Ginkgo biloba; Male; Neuroprotective Agents;

2004
Fibroblast growth factor-20 promotes the differentiation of Nurr1-overexpressing neural stem cells into tyrosine hydroxylase-positive neurons.
    Neurobiology of disease, 2004, Volume: 17, Issue:2

    Topics: Animals; Brain Diseases; Cell Differentiation; Cell Line; Corpus Striatum; DNA-Binding Proteins; Dop

2004
Selective effects of partial striatal 6-OHDA lesions on information processing in the rat.
    The European journal of neuroscience, 2005, Volume: 21, Issue:7

    Topics: Adrenergic Agents; Animals; Behavior, Animal; Brain Chemistry; Brain Diseases; Brain Injuries; Choic

2005
Neuroprotective effects of caffeine in the model of 6-hydroxydopamine lesion in rats.
    Pharmacology, biochemistry, and behavior, 2006, Volume: 84, Issue:3

    Topics: Animals; Apomorphine; Brain; Brain Diseases; Caffeine; Disease Models, Animal; Dopamine Agents; Male

2006
Midbrain dopaminergic neurogenesis and behavioural recovery in a salamander lesion-induced regeneration model.
    Development (Cambridge, England), 2007, Volume: 134, Issue:15

    Topics: Animals; Behavior, Animal; Brain Diseases; Cell Differentiation; Dopamine; Mesencephalon; Models, An

2007
Accelerated regeneration of central catecholamine fibers in cat occipital cortex: effects of substance P.
    Brain research, 1984, Dec-10, Volume: 323, Issue:2

    Topics: Animals; Bethanechol; Bethanechol Compounds; Brain Diseases; Cats; Histocytochemistry; Hydroxydopami

1984
Pergolide-induced circling in rats with 6-hydroxydopamine lesions in the nigrostriatal pathway.
    Neurology, 1982, Volume: 32, Issue:12

    Topics: Animals; Behavior, Animal; Brain Diseases; Bromocriptine; Ergolines; Female; Hydroxydopamines; Oxido

1982
Behavioral and neuronal reorganization after unilateral substantia nigra lesions: evidence for increased interhemispheric nigrostriatal projections.
    Neuroscience, 1983, Volume: 9, Issue:4

    Topics: Animals; Behavior, Animal; Brain Diseases; Brain Mapping; Catecholamines; Corpus Striatum; Hydroxydo

1983
GM1 ganglioside enhances regrowth of noradrenaline nerve terminals in rat cerebral cortex lesioned by the neurotoxin 6-hydroxydopamine.
    Neuroscience, 1984, Volume: 13, Issue:4

    Topics: Adrenergic Fibers; Animals; Brain Diseases; Cerebral Cortex; G(M1) Ganglioside; Gangliosides; Hydrox

1984
Effects of specific dopamine lesions and dopamine receptor sensitivity on angiotensin II- and carbachol-induced thirst in rats.
    Psychopharmacology, 1981, Volume: 73, Issue:2

    Topics: Angiotensin II; Animals; Brain Diseases; Carbachol; Corpus Striatum; Dopamine; Haloperidol; Hydroxyd

1981
Interactions of dopaminergic and GABAergic neurotransmission: impact of 6-hydroxydopamine lesions into the substantia nigra of rats.
    The Journal of pharmacology and experimental therapeutics, 1995, Volume: 275, Issue:1

    Topics: Animals; Brain Diseases; Corpus Striatum; Cyclic AMP; Dopamine; Dopamine Agonists; Dopamine Antagoni

1995
Specific lesions in the extrapyramidal system of the rat brain induced by 3-nitropropionic acid (3-NPA).
    Experimental neurology, 1995, Volume: 132, Issue:1

    Topics: Animals; Base Sequence; Behavior, Animal; Brain Diseases; Corpus Striatum; Dopamine; Female; Male; M

1995
Influence of previous exposure to levodopa on the interaction between dizocilpine and dopamine D1 and D2 agonists in rats with 6-hydroxydopamine-induced lesions.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 267, Issue:3

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Behavior, Animal; Brain Disease

1993
A video image analyzing system for open-field behavior in the rat focusing on behavioral asymmetries.
    Journal of neuroscience methods, 1993, Volume: 49, Issue:3

    Topics: Animals; Behavior, Animal; Brain Diseases; Computers; Dopamine Agents; Image Processing, Computer-As

1993
Behavioral assessment of the effects of embryonic nigral grafts in marmosets with unilateral 6-OHDA lesions of the nigrostriatal pathway.
    Experimental neurology, 1994, Volume: 125, Issue:2

    Topics: Animals; Behavior, Animal; Brain Diseases; Brain Tissue Transplantation; Callithrix; Caudate Nucleus

1994
Glutamate uptake blockade induces striatal dopamine release in 6-hydroxydopamine rats with intrastriatal grafts: evidence for host modulation of transplanted dopamine neurons.
    Experimental neurology, 1994, Volume: 127, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Brain Diseases; Brain Tissue Transplantation; Corpus

1994
Grafting of dopaminergic ventral mesencephalic slice cultures to the striatum of adult rats.
    Experimental neurology, 1994, Volume: 127, Issue:2

    Topics: Animals; Animals, Newborn; Brain Diseases; Brain Tissue Transplantation; Corpus Striatum; Culture Te

1994
Quantitation of the levels of tyrosine hydroxylase and preproenkephalin mRNAs in nigrostriatal sites after 6-hydroxydopamine lesions.
    Life sciences, 1993, Volume: 52, Issue:19

    Topics: Animals; Apomorphine; Brain Diseases; Corpus Striatum; Dopamine; Enkephalins; Gene Expression; Male;

1993
Turning behavior induced by intrastriatal injection of neurotensin in mice: sensitivity to non-peptide neurotensin antagonists.
    Naunyn-Schmiedeberg's archives of pharmacology, 1994, Volume: 349, Issue:1

    Topics: Animals; Behavior, Animal; Brain Diseases; Corpus Striatum; Dopamine; Dose-Response Relationship, Dr

1994
Locomotor activation induced by MK-801 in the rat: postsynaptic interactions with dopamine receptors in the ventral striatum.
    European journal of pharmacology, 1994, Jan-14, Volume: 251, Issue:2-3

    Topics: Amphetamine; Animals; Brain; Brain Diseases; Corpus Striatum; Dizocilpine Maleate; Dopamine; Dopamin

1994
Dopaminergic functional supersensitivity: effects of chronic L-dopa and carbidopa treatment in an animal model of Parkinson's disease.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 267, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biopterins; Brain Diseases; Carbidopa; Corpus Striatum; Cyc

1993
The vesamicol receptor ligand (+)-meta-[125I]iodobenzyltrozamicol [(+)-[125I]-MIBT] reveals blunting of the striatal cholinergic response to dopamine D2 receptor blockade in the 6-hydroxydopamine (6-OHDA)-lesioned rat: possible implications for Parkinson'
    Life sciences, 1996, Volume: 58, Issue:16

    Topics: Animals; Brain Diseases; Cholinergic Fibers; Corpus Striatum; Disease Models, Animal; Dopamine Antag

1996
Adenosine A2A receptor antagonism potentiates L-DOPA-induced turning behaviour and c-fos expression in 6-hydroxydopamine-lesioned rats.
    European journal of pharmacology, 1997, Feb-26, Volume: 321, Issue:2

    Topics: Animals; Behavior, Animal; Brain Diseases; Dopamine Agonists; Drug Synergism; Gene Expression; Genes

1997
Sequential changes of dopaminergic receptors in the rat brain after 6-hydroxydopamine lesions of the medial forebrain bundle.
    Journal of the neurological sciences, 1998, Oct-08, Volume: 160, Issue:2

    Topics: Adrenergic Agents; Animals; Autoradiography; Benzamides; Benzazepines; Brain Diseases; Dopamine; Dop

1998
Multiple single-unit recordings in the striatum of freely moving animals: effects of apomorphine and D-amphetamine in normal and unilateral 6-hydroxydopamine-lesioned rats.
    Brain research, 1999, Jun-26, Volume: 833, Issue:1

    Topics: Anesthesia; Anesthetics, Intravenous; Animals; Apomorphine; Brain Diseases; Corpus Striatum; Dextroa

1999
Gene expression of the GAD67 and GAD65 isoforms of glutamate decarboxylase is differentially altered in subpopulations of striatal neurons in adult rats lesioned with 6-OHDA as neonates.
    Synapse (New York, N.Y.), 1999, Volume: 33, Issue:1

    Topics: Animals; Animals, Newborn; Brain Diseases; Corpus Striatum; Dynorphins; Enkephalins; Gene Expression

1999
Modulation of latent inhibition in the rat by altered dopamine transmission in the nucleus accumbens at the time of conditioning.
    Neuroscience, 2000, Volume: 101, Issue:4

    Topics: Amphetamine; Animals; Association Learning; Behavior, Animal; Brain Diseases; Conditioning, Psycholo

2000
Unilateral lesion of the nigrostriatal pathway induces a transient decrease of firing rate with no change in the firing pattern of neurons of the parafascicular nucleus in the rat.
    Neuroscience, 2000, Volume: 101, Issue:4

    Topics: Action Potentials; Animals; Brain Diseases; Corpus Striatum; Electrophysiology; Immunohistochemistry

2000
Injury induced c-Jun expression and phosphorylation in the dopaminergic nigral neurons of the rat: correlation with neuronal death and modulation by glial-cell-line-derived neurotrophic factor.
    The European journal of neuroscience, 2001, Volume: 13, Issue:1

    Topics: Aging; Animals; Animals, Newborn; Brain Diseases; Cell Death; Dopamine; Female; Glial Cell Line-Deri

2001
Dopamine mediates striatal malonate toxicity via dopamine transporter-dependent generation of reactive oxygen species and D2 but not D1 receptor activation.
    Journal of neurochemistry, 2001, Volume: 79, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; alpha-Methyltyrosine; Animals; Benzazepines; Brain Diseases; Carbido

2001
Erectile dysfunction occurs following substantia nigra lesions in the rat.
    International journal of impotence research, 2001, Volume: 13, Issue:5

    Topics: Animals; Apomorphine; Behavior, Animal; Brain Diseases; Corpus Striatum; Dopamine; Dopamine Agonists

2001
Aggravation of 6-hydroxydopamine-induced dopaminergic lesions in metallothionein-I and -II knock-out mouse brain.
    Neuroscience letters, 2002, Jul-12, Volume: 327, Issue:1

    Topics: Animals; Brain; Brain Diseases; Denervation; Dopamine Plasma Membrane Transport Proteins; Injections

2002
Changes in striatal dopamine neurotransmission assessed with microdialysis following recovery from a bilateral 6-OHDA lesion: variation as a function of lesion size.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1990, Volume: 10, Issue:6

    Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Brain Diseases; Corpus Striatum; Dialysis; Dop

1990
Behavioral and biochemical effects of a novel calcium antagonist, KB-2796, on the central dopaminergic system.
    European journal of pharmacology, 1991, Aug-06, Volume: 200, Issue:2-3

    Topics: Animals; Apomorphine; Behavior, Animal; Biogenic Monoamines; Brain; Brain Diseases; Calcium Channel

1991
Cocaine-induced turning behavior in rats with 6-hydroxydopamine lesions: effect of transplants of fetal substantia nigra.
    European journal of pharmacology, 1991, Dec-10, Volume: 209, Issue:1-2

    Topics: Amphetamine; Animals; Apomorphine; Behavior, Animal; Brain Diseases; Brain Tissue Transplantation; C

1991
Axonal transport of beta-receptors during the response to axonal injury and repair in locus coeruleus neurons.
    Brain research, 1985, Dec-16, Volume: 359, Issue:1-2

    Topics: Animals; Axonal Transport; Brain Diseases; Catecholamines; Hydroxydopamines; Locus Coeruleus; Male;

1985
Substantia nigra transplants into denervated striatum of the rat: ultrastructure of graft and host interconnections.
    The Journal of comparative neurology, 1985, Oct-01, Volume: 240, Issue:1

    Topics: Animals; Brain Diseases; Corpus Striatum; Hydroxydopamines; Microscopy, Electron; Oxidopamine; Rats;

1985
Effects of dopamine-rich grafts on conditioned rotation in rats with unilateral 6-hydroxydopamine lesions.
    Neuroscience letters, 1986, Jul-11, Volume: 68, Issue:1

    Topics: Animals; Behavior, Animal; Brain; Brain Diseases; Conditioning, Psychological; Corpus Striatum; Dopa

1986
Differential time-course of reaction time recovery depending on variations in the amplitude of a goal-directed movement after nigrostriatal lesion in monkeys.
    Neuroscience letters, 1986, Jul-11, Volume: 68, Issue:1

    Topics: Animals; Brain Diseases; Caudate Nucleus; Corpus Striatum; Dopamine; Hydroxydopamines; Motor Activit

1986
Characterization of binding of 3H-SCH 23390 to dopamine D-1 receptors. Correlation to other D-1 and D-2 measures and effect of selective lesions.
    Journal of neural transmission, 1987, Volume: 68, Issue:3-4

    Topics: Animals; Antipsychotic Agents; Benzazepines; Brain; Brain Diseases; Hydroxydopamines; Male; Oxidopam

1987
The neostriatal mosaic: III. Biochemical and developmental dissociation of patch-matrix mesostriatal systems.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1987, Volume: 7, Issue:12

    Topics: Animals; Brain Diseases; Calbindins; Corpus Striatum; Dopamine; Hydroxydopamines; Mesencephalon; Neu

1987
Developmental changes in the cerebellar cortex after locus ceruleus lesion with 6-hydroxydopamine in the rat.
    Experimental neurology, 1985, Volume: 88, Issue:1

    Topics: Animals; Brain Diseases; Cerebellum; Cerebral Cortex; Hydroxydopamines; Locus Coeruleus; Oxidopamine

1985
The formation of new neuronal circuit between transplanted nigral dopamine neurons and non-immunoreactive axon terminals in the host rat caudate nucleus.
    Neuroscience letters, 1986, Feb-14, Volume: 64, Issue:1

    Topics: Animals; Brain Diseases; Dopamine; Female; Graft Survival; Hydroxydopamines; Microscopy, Electron; M

1986
Transplants in the peri- and intraventricular region grow better than those in the central parenchyma of the caudate.
    Neuroscience letters, 1986, Feb-28, Volume: 64, Issue:2

    Topics: Animals; Brain Diseases; Corpus Striatum; Dopamine; Hydroxydopamines; Mesencephalon; Methamphetamine

1986
Short-term effects of dopamine-depleting brain lesions on spontaneous activity of striatal neurons: relation to local dopamine concentration and behavior.
    Brain research, 1986, Jun-18, Volume: 376, Issue:1

    Topics: Animals; Behavior, Animal; Brain Diseases; Corpus Striatum; Dopamine; Hydroxydopamines; Injections,

1986
Long-term effects of dopamine-depleting brain lesions on spontaneous activity of type II striatal neurons: relation to behavioral recovery.
    Brain research, 1986, Nov-29, Volume: 398, Issue:2

    Topics: Action Potentials; Animals; Brain Diseases; Corpus Striatum; Dopamine; Haloperidol; Hydroxydopamines

1986
Spontaneous and graft-induced behavioral recovery after 6-hydroxydopamine lesion of the nucleus accumbens in the rat.
    Brain research, 1987, Mar-31, Volume: 407, Issue:2

    Topics: Animals; Brain Diseases; Corpus Striatum; Dopamine; Female; Hydroxydopamines; Mesencephalon; Nucleus

1987
The role of dopamine in intracranial self-stimulation of the ventral tegmental area.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1987, Volume: 7, Issue:12

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Diseases; Corpus Striatum; Dopamine; Electric Stimula

1987
Imaging of the degeneration of neurons and their processes in rat or cat brain by 45CaCl2 autoradiography or 55CoCl2 positron emission tomography.
    Journal of neurochemistry, 1988, Volume: 50, Issue:6

    Topics: Animals; Autoradiography; Brain; Brain Diseases; Calcium; Calcium Chloride; Calcium Radioisotopes; C

1988
Mechanisms of hypoglycemic brain damage. Evidence against a significant role of the noradrenergic locus coeruleus system.
    Experimental brain research, 1988, Volume: 73, Issue:1

    Topics: Animals; Brain Diseases; Hydroxydopamines; Hypoglycemia; Locus Coeruleus; Male; Norepinephrine; Oxid

1988
Transplant-induced recovery from 6-OHDA lesions of the nigrostriatal dopamineneurones in mice.
    Acta neurochirurgica. Supplementum, 1988, Volume: 43

    Topics: Animals; Brain Diseases; Corpus Striatum; Dopamine; Female; Hydroxydopamines; Mice; Mice, Inbred C3H

1988
Survival of intracerebrally grafted rat dopamine neurons previously cultured in vitro.
    Neuroscience letters, 1985, Oct-24, Volume: 61, Issue:1-2

    Topics: Animals; Brain Diseases; Cells, Cultured; Corpus Striatum; Dopamine; Female; Fetus; Hydroxydopamines

1985
Head displacement and bracing in haloperidol-treated rats compared to rats with lateral hypothalamic damage.
    Physiology & behavior, 1985, Volume: 35, Issue:5

    Topics: Animals; Brain Diseases; Catalepsy; Disease Models, Animal; Haloperidol; Hydroxydopamines; Hypothala

1985