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oxidopamine and Bone Loss, Osteoclastic

oxidopamine has been researched along with Bone Loss, Osteoclastic in 3 studies

Oxidopamine: A neurotransmitter analogue that depletes noradrenergic stores in nerve endings and induces a reduction of dopamine levels in the brain. Its mechanism of action is related to the production of cytolytic free-radicals.
oxidopamine : A benzenetriol that is phenethylamine in which the hydrogens at positions 2, 4, and 5 on the phenyl ring are replaced by hydroxy groups. It occurs naturally in human urine, but is also produced as a metabolite of the drug DOPA (used for the treatment of Parkinson's disease).

Research Excerpts

ExcerptRelevanceReference
"The stress group rats showed increased bone resorption in contrast to the sympathectomy and control group rats."1.36The effect of chemical sympathectomy and stress on bone remodeling in adult rats. ( Ding, Y; Hou, R; Hu, K; Kong, L; Qin, R; Zhang, G; Zhou, H, 2010)
"HDA-induced sympathectomy increases bone resorption in gerbilline middle ear bone."1.31Effect of chemical sympathectomy with 6-hydroxydopamine on osteoclast activity in the gerbilline middle ear bulla. ( Chole, RA; Sherman, BE, 2001)
"Substance P has thus been shown to induce calcium release from membranous bone in vitro, whereas capsaicin, a substance P-specific sensory neurolytic chemical, eliminates the in vivo osteoclast-inductive effects of 6-hydroxydopamine when given 12 hours before treatment."1.29A mechanism for sympathectomy-induced bone resorption in the middle ear. ( Chole, RA; Sherman, BE, 1995)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's1 (33.33)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hu, K1
Zhou, H1
Zhang, G1
Qin, R1
Hou, R1
Kong, L1
Ding, Y1
Sherman, BE2
Chole, RA2

Other Studies

3 other studies available for oxidopamine and Bone Loss, Osteoclastic

ArticleYear
The effect of chemical sympathectomy and stress on bone remodeling in adult rats.
    Neuro endocrinology letters, 2010, Volume: 31, Issue:6

    Topics: Absorptiometry, Photon; Animals; Bone Density; Bone Remodeling; Bone Resorption; Calcium; Disease Mo

2010
A mechanism for sympathectomy-induced bone resorption in the middle ear.
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 1995, Volume: 113, Issue:5

    Topics: Animals; Animals, Newborn; Awards and Prizes; Bone and Bones; Bone Resorption; Calcium; Capsaicin; C

1995
Effect of chemical sympathectomy with 6-hydroxydopamine on osteoclast activity in the gerbilline middle ear bulla.
    Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology, 2001, Volume: 22, Issue:2

    Topics: Animals; Animals, Newborn; Bone Resorption; Calcium; Cell Count; Ear, Middle; Gerbillinae; Osteoclas

2001