oxidopamine has been researched along with Blood Pressure, High in 58 studies
Oxidopamine: A neurotransmitter analogue that depletes noradrenergic stores in nerve endings and induces a reduction of dopamine levels in the brain. Its mechanism of action is related to the production of cytolytic free-radicals.
oxidopamine : A benzenetriol that is phenethylamine in which the hydrogens at positions 2, 4, and 5 on the phenyl ring are replaced by hydroxy groups. It occurs naturally in human urine, but is also produced as a metabolite of the drug DOPA (used for the treatment of Parkinson's disease).
Excerpt | Relevance | Reference |
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"Cocaine causes hypertension at least in part by stimulating the sympathetic nervous system, but it is not clear if this effect is centrally or peripherally mediated." | 7.70 | Cocaine-induced hypertension: role of the peripheral sympathetic system. ( Arruda, JA; Dunea, G; Mo, W; Singh, AK, 1999) |
" To assess whether these differential structural effects do translate into different effects on LV function and on heart failure mortality, Bd or sham Bd 8-week-old rats were randomized to vehicle treatment (Vh), chemical sympathectomy ([Sx] 6-hydroxydopamine, 150 mg/kg IP twice a week), beta-adrenoceptor blockade (propranolol [Pro], 40 mg/kg per day PO), or alpha-adrenoceptor blockade (doxazosin [Dox], 5 mg/kg per day PO)." | 3.73 | Survival benefits of different antiadrenergic interventions in pressure overload left ventricular hypertrophy/failure. ( Busca, G; Cesana, F; Clari, F; Ferrari, AU; Ferrero, I; Gatti, C; Janetti, MB; Mancia, G; Palladini, G; Perlini, S; Tozzi, R; Vezzoli, M, 2006) |
"Cocaine causes hypertension at least in part by stimulating the sympathetic nervous system, but it is not clear if this effect is centrally or peripherally mediated." | 3.70 | Cocaine-induced hypertension: role of the peripheral sympathetic system. ( Arruda, JA; Dunea, G; Mo, W; Singh, AK, 1999) |
" The effects of isoproterenol (ISP) and chemical sympathectomy (6-hydroxydopamine treatment) on myocardial beta-receptors were also investigated in 10 and 24 week-old SHRS and WKY to examine the effects of hypertension and aging on receptor regulation." | 3.68 | Effects of aging and drugs on myocardial beta-adrenergic receptors in M-SHRSP and SHRSP. ( Ikawa, H; Suzuki, A, 1991) |
" The potency and efficacy of isoproterenol (ISO) in these arteries were decreased in SHR before and during the development of hypertension as compared with age-matched Wistar Kyoto rats (WKY)." | 3.67 | Diminished beta-adrenoceptor-mediated relaxation of arteries from spontaneously hypertensive rats before and during development of hypertension. ( Aoki, K; Asano, M; Dohi, Y; Fujimoto, S; Matsuda, T, 1987) |
"To study the possible influence of sympathetic adrenergic tone on the blood-brain barrier function during acute hypertension in conscious unrestrained rats with indwelling catheters in the aorta and a jugular vein the blood pressure was increase by noradrenaline, 6-hydroxydopamine (6-OHDA) or baclofen." | 3.66 | Neurogenic modification of the vulnerability of the blood-brain barrier during acute hypertension in conscious rats. ( Auer, LM; Johansson, BB, 1983) |
" However, it is also known to accumulate in various tissues up to several times higher after standard oral dosing and we now have evidence from both in vivo and in vitro experiments with spontaneously hypertensive rats (SHR) that millimolar levels stimulate release of norepinephrine (NE) from vascular sympathetic nerve endings (SNEs)." | 1.31 | A possible indirect sympathomimetic action of metformin in the arterial vessel wall of spontanously hypertensive rats. ( Lee, JM; Peuler, JD, 2001) |
"Captopril was given (30 or 100 mg kg(-l) day(-l); p." | 1.31 | Angiotensin converting enzyme inhibition prevents trophic and hypertensive effects of an antagonist of adenosine receptors. ( Albino-Teixeira, A; Morato, M; Sousa, T, 2002) |
"Our data imply that repetitive hypoxemia in SAS is probably the cause of the high prevalence of systemic hypertension in this population and that peripheral chemoreceptors and the sympathetic nervous system play important roles in this pathophysiologic process." | 1.30 | Hypertension caused by chronic intermittent hypoxia--influence of chemoreceptors and sympathetic nervous system. ( Bao, G; Fletcher, EC; Lesske, J; Unger, T, 1997) |
"In control group (WKY rat + NaCl), gastric cancers were found in 2 (11%) of 18 rats examined in week 52." | 1.28 | Inhibition by 6-hydroxydopamine of enhanced gastric carcinogenesis induced by N-methyl-N'-nitro-N-nitrosoguanidine in spontaneously hypertensive rats. ( Baba, M; Iishi, H; Taniguchi, H; Tatsuta, M, 1992) |
"In fetal sheep, hypoxemia causes arterial hypertension, bradycardia, a redistribution of blood flow, and an increase in plasma vasopressin and catecholamine concentrations." | 1.27 | Circulatory and humoral responses of sympathectomized fetal sheep to hypoxemia. ( Iwamoto, HS; Keil, LC; Mirkin, BL; Rudolph, AM, 1983) |
"We suggest that A1 hypertension is predominantly mediated through increased activity of sympathetic vasoconstrictor nerves, and that circulating adrenaline and vasopressin only make a minor contribution to the increase in pressure." | 1.27 | Hypertension after brainstem (A1) lesions in normal rats and in rats with adrenalectomy, sympathectomy or diabetes insipidus. ( Cain, M; Chalmers, J; Kapoor, V; Minson, J, 1984) |
" The mesenteric arteries from all three types of hypertensive rats showed an increased reactivity to noradrenaline as characterized by a steeper dose-response curve and elevated maximal vasoconstriction when compared with normotensive controls." | 1.27 | Vascular reactivity of rats after prevention of hypertension by central administration of 6-hydroxydopamine. ( Haeusler, G, 1984) |
"The captopril-treated rats had a significant elevation in serum renin activity at 12 weeks of age indicating the presence of chronic converting enzyme inhibition, and the 6-OHDA-treatment resulted in a depletion of hypothalamic (86%) and brainstem (76%) norepinephrine content." | 1.27 | Abnormalities in hypothalamic and neurohypophysial vasopressin content are not a consequence of hypertension in the spontaneously hypertensive rat. ( Aravich, PF; Blair, ML; Devine, MA; Felten, SY; Sladek, CD, 1988) |
" Dose-response curves to serotonin were shifted to the left in femoral arteries from DOCA-treated rats compared to both control and 6-OHDA-DOCA-treated rats (ED50: DOCA = 6." | 1.27 | Cerebral intraventricular 6-hydroxydopamine prevents vascular changes in the mineralocorticoid hypertensive rat. ( Hall, JL; Lamb, FS; Mecca, TE; Webb, RC, 1985) |
" 6-OH-DA in the dosage applied, induces during its time of action in NR a smaller, in SHR a larger decrease of blood pressure and, presumably induced by intense NA-depletion of the myocardium, myocardial alterations." | 1.26 | [Functional and structural behavior of the cardiovascular system of normotonic and spontaneously hypertensive rats following chemical sympathectomy and angiotensin administration]. ( Becker, CH; Engler, E; Matthias, D; Moritz, V; Schmidt, R; Will-Shahab, L, 1981) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 36 (62.07) | 18.7374 |
1990's | 16 (27.59) | 18.2507 |
2000's | 4 (6.90) | 29.6817 |
2010's | 2 (3.45) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Banegas, I | 2 |
Prieto, I | 2 |
Vives, F | 2 |
Alba, F | 2 |
de Gasparo, M | 2 |
Duran, R | 2 |
Luna, Jde D | 1 |
Segarra, AB | 2 |
Hermoso, F | 1 |
Ramírez, M | 1 |
Luna, JD | 1 |
Wangesteen, R | 1 |
Ruiz-Bailén, M | 1 |
Ramírez-Sánchez, M | 1 |
Chaswal, M | 1 |
Das, S | 1 |
Prasad, J | 1 |
Katyal, A | 1 |
Fahim, M | 1 |
Perlini, S | 1 |
Ferrero, I | 1 |
Palladini, G | 1 |
Tozzi, R | 1 |
Gatti, C | 1 |
Vezzoli, M | 1 |
Cesana, F | 1 |
Janetti, MB | 1 |
Clari, F | 1 |
Busca, G | 1 |
Mancia, G | 1 |
Ferrari, AU | 1 |
Takahashi, H | 1 |
Inoue, A | 1 |
Takeda, K | 2 |
Okajima, H | 1 |
Sasaki, S | 2 |
Yoshimura, M | 1 |
Nakagawa, M | 2 |
Ijichi, H | 1 |
U'Prichard, DC | 1 |
Dadkar, NK | 1 |
Aroskar, VA | 1 |
Gupte, RD | 1 |
Dohadwalla, AN | 1 |
Howes, LG | 1 |
Kubo, T | 1 |
Misu, Y | 1 |
Chatelain, P | 2 |
Robberecht, P | 2 |
Camus, JC | 1 |
De Neef, P | 1 |
Waelbroeck, M | 2 |
Roba, J | 2 |
Christophe, J | 2 |
Bloom, FE | 1 |
Baetge, G | 1 |
Deyo, S | 1 |
Ettenberg, A | 1 |
Koda, L | 1 |
Magistretti, PJ | 1 |
Shoemaker, WJ | 1 |
Staunton, DA | 1 |
Huu, AN | 1 |
Johansson, BB | 2 |
Auer, LM | 1 |
Iwamoto, HS | 1 |
Rudolph, AM | 1 |
Mirkin, BL | 1 |
Keil, LC | 1 |
van den Buuse, M | 4 |
de Kloet, ER | 1 |
Versteeg, DH | 3 |
de Jong, W | 4 |
Rodionov, IM | 1 |
Markov, KhM | 1 |
Pinelis, VG | 1 |
Kozlov, AV | 1 |
Koshelev, VB | 1 |
Chalmers, J | 2 |
Minson, J | 2 |
Kapoor, V | 2 |
Cain, M | 2 |
Haeusler, G | 1 |
Ben-Menachem, E | 1 |
Svensson, TH | 1 |
Matthias, D | 1 |
Moritz, V | 1 |
Engler, E | 1 |
Will-Shahab, L | 1 |
Schmidt, R | 1 |
Becker, CH | 1 |
Lin, MT | 2 |
Yang, JJ | 1 |
Chu, TF | 1 |
Leont'eva, GR | 1 |
Zicha, J | 1 |
Kunes, J | 1 |
Lesske, J | 1 |
Fletcher, EC | 1 |
Bao, G | 1 |
Unger, T | 1 |
Mo, W | 1 |
Arruda, JA | 1 |
Dunea, G | 1 |
Singh, AK | 1 |
Lee, JM | 1 |
Peuler, JD | 1 |
Sousa, T | 1 |
Morato, M | 1 |
Albino-Teixeira, A | 1 |
Tatsuta, M | 1 |
Iishi, H | 1 |
Baba, M | 1 |
Taniguchi, H | 1 |
Li, M | 1 |
Whitworth, JA | 1 |
Ikawa, H | 1 |
Suzuki, A | 1 |
Kawasaki, S | 1 |
Tanaka, M | 1 |
Itoh, H | 1 |
Hirata, M | 1 |
Nakata, T | 1 |
Hayashi, J | 1 |
Oguro, M | 1 |
Yang, K | 1 |
Ding, H | 1 |
Zhou, Q | 1 |
Luo, HY | 1 |
Wu, ZY | 1 |
Thomas, GD | 3 |
O'Hagan, KP | 2 |
Zambraski, EJ | 3 |
Kobayashi, H | 1 |
Hayashi, M | 1 |
Kawano, H | 1 |
Handa, Y | 1 |
Kabuto, M | 1 |
Ide, H | 1 |
Montero, S | 1 |
Fuentes, JA | 1 |
Fernandez-Tome, P | 1 |
Kujirai, K | 1 |
Przedborski, S | 1 |
Kostic, V | 1 |
Jackson-Lewis, V | 1 |
Fahn, S | 1 |
Cadet, JL | 1 |
Zidek, W | 1 |
Ottens, E | 1 |
Heckmann, U | 1 |
Dabsys, SM | 1 |
Balda, MS | 1 |
Pirola, CJ | 1 |
Finkielman, S | 1 |
Nahmod, VE | 1 |
Lappe, RW | 1 |
Todt, JA | 1 |
Wendt, RL | 1 |
Schwartz, D | 1 |
Katsube, NC | 1 |
Needleman, P | 1 |
Sattar, MA | 1 |
Latiff, A | 1 |
Gan, EK | 1 |
Fujimoto, S | 1 |
Dohi, Y | 1 |
Aoki, K | 1 |
Asano, M | 1 |
Matsuda, T | 1 |
Michel, MC | 1 |
Wang, XL | 1 |
Schlicker, E | 1 |
Göthert, M | 1 |
Beckeringh, JJ | 1 |
Brodde, OE | 1 |
Veldhuis, HD | 1 |
de Boer, S | 1 |
Caon, A | 1 |
Versteeq, DH | 1 |
Nyborg, NC | 1 |
Korsgaard, N | 1 |
Mulvany, MJ | 1 |
Nakada, T | 1 |
Kimura, M | 1 |
Watanabe, H | 1 |
Yamori, Y | 1 |
Lovenberg, W | 1 |
Hall, JL | 2 |
Mecca, TE | 2 |
Malvin, RL | 1 |
Webb, RC | 2 |
Head, GA | 1 |
Howe, PR | 1 |
Nag, S | 1 |
Harik, SI | 1 |
Sladek, CD | 1 |
Devine, MA | 1 |
Felten, SY | 1 |
Aravich, PF | 1 |
Blair, ML | 1 |
Caccia, C | 1 |
Achilli, G | 1 |
Buonamici, M | 1 |
Carpentieri, M | 1 |
Cervini, MA | 1 |
Maj, R | 1 |
Pegrassi, L | 1 |
Rossi, AC | 1 |
Otorii, T | 1 |
Ohkubo, K | 1 |
Suzuki, K | 1 |
Lamb, FS | 1 |
4 reviews available for oxidopamine and Blood Pressure, High
Article | Year |
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Biochemical characteristics and regulation of brain alpha 2-adrenoceptors.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brain; Clonidine; Epinephrine; Hum | 1984 |
Central catecholaminergic neurones and spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Brain; Brain Chemistry; Catecholamines; Dopamine beta-Hydroxylase; Hydroxyd | 1984 |
Chemical and physiological aspects of the actions of lithium and antidepressant drugs.
Topics: Animals; Antidepressive Agents; Apomorphine; Blood Pressure; Brain Chemistry; Diet; Endorphins; Halo | 1983 |
Atriopeptins in fluid and electrolyte homeostasis.
Topics: Animals; Atrial Natriuretic Factor; Blood Volume; Deamino Arginine Vasopressin; Dogs; Hydroxydopamin | 1986 |
54 other studies available for oxidopamine and Blood Pressure, High
Article | Year |
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Asymmetrical response of aminopeptidase A and nitric oxide in plasma of normotensive and hypertensive rats with experimental hemiparkinsonism.
Topics: Animals; Blood Pressure; Corpus Striatum; Functional Laterality; Glutamyl Aminopeptidase; Hypertensi | 2009 |
Blood pressure increased dramatically in hypertensive rats after left hemisphere lesions with 6-hydroxydopamine.
Topics: Animals; Blood Pressure; Corpus Striatum; Functional Laterality; Heart Rate; Hypertension; Male; Oxi | 2011 |
Cardiac autonomic function in acutely nitric oxide deficient hypertensive rats: role of the sympathetic nervous system and oxidative stress.
Topics: Animals; Baroreflex; Heart; Heart Rate; Hypertension; Male; NG-Nitroarginine Methyl Ester; Nitric Ox | 2011 |
Survival benefits of different antiadrenergic interventions in pressure overload left ventricular hypertrophy/failure.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Aorta, Abdominal; Blood Pressure | 2006 |
Augmented central cholinergic mechanisms in spontaneously hypertensive rats. Involvement of deranged noradrenergic mechanisms in the brain.
Topics: Animals; Blood Pressure; Brain; Carbachol; Heart Rate; Hemodynamics; Hydroxydopamines; Hypertension; | 1984 |
Central pressor activity of cimetidine in spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Brain; Cimetidine; Hydroxydopamines; Hypertension; Male; Norepinephrine; Ox | 1984 |
Anti-hypertensive effects of propranolol unaltered by 6-hydroxydopamine given intraventricularly to SHR.
Topics: Animals; Blood Pressure; Brain; Female; Heart Rate; Hydroxydopamines; Hypertension; Injections, Intr | 1981 |
The adenylate cyclase activity in heart membranes from normotensive and spontaneously hypertensive rats, after chemical sympathectomy, suggests the presence of presynaptic secretin receptors.
Topics: Adenylyl Cyclases; Animals; Blood Pressure; Body Weight; Heart; Heart Rate; Hydroxydopamines; Hypert | 1983 |
Effects of a chemical sympathectomy on cardiac muscarinic receptors in normotensive (WKY) and spontaneously hypertensive (SHR) rats.
Topics: Animals; Heart Rate; Hydroxydopamines; Hypertension; Male; Muscarinic Antagonists; Oxidopamine; Rats | 1983 |
Neurogenic modification of the vulnerability of the blood-brain barrier during acute hypertension in conscious rats.
Topics: Adrenergic Fibers; Animals; Baclofen; Blood-Brain Barrier; Carbon Dioxide; Clonidine; Hydroxydopamin | 1983 |
Circulatory and humoral responses of sympathectomized fetal sheep to hypoxemia.
Topics: Animals; Blood Pressure; Dopamine; Female; Fetus; Heart; Heart Rate; Hemoglobins; Hydroxydopamines; | 1983 |
Regional brain catecholamine levels and the development of hypertension in the spontaneously hypertensive rat: the effect of 6-hydroxydopamine.
Topics: Animals; Blood Pressure; Brain; Brain Mapping; Catecholamines; Caudate Nucleus; Dopamine; Epinephrin | 1984 |
[Role of sympathetic nervous system in the pathogenesis of spontaneous hypertension in rats].
Topics: Animals; Arteries; Blood Pressure; Cardiac Output; Guanethidine; Hindlimb; Hydroxydopamines; Hyperte | 1984 |
Hypertension after brainstem (A1) lesions in normal rats and in rats with adrenalectomy, sympathectomy or diabetes insipidus.
Topics: Adrenal Glands; Adrenalectomy; Animals; Arginine Vasopressin; Brain Stem; Diabetes Insipidus; Epinep | 1984 |
Vascular reactivity of rats after prevention of hypertension by central administration of 6-hydroxydopamine.
Topics: Animals; Desoxycorticosterone; Hydroxydopamines; Hypertension; In Vitro Techniques; Injections, Intr | 1984 |
Increased vulnerability of the blood-brain barrier to acute hypertension following depletion of brain noradrenaline.
Topics: Acute Disease; Animals; Blood-Brain Barrier; Brain Chemistry; Hydroxydopamines; Hypertension; Male; | 1982 |
[Functional and structural behavior of the cardiovascular system of normotonic and spontaneously hypertensive rats following chemical sympathectomy and angiotensin administration].
Topics: Angiotensin II; Animals; Blood Circulation; Coronary Circulation; Hydroxydopamines; Hypertension; Ma | 1981 |
Stimulation of the nigrostriatal dopamine system produces hypertension and tachycardia in rats.
Topics: Animals; Cardiovascular Physiological Phenomena; Cardiovascular System; Corpus Striatum; Dopamine; D | 1994 |
Picrotoxin induces both hypertension and dopamine release in the rat amygdala.
Topics: Amygdala; Animals; Anticonvulsants; Cardiovascular System; Convulsants; Diazepam; Dopamine; Dopamine | 1996 |
[The effect of chemical sympathectomy on the adrenergic innervation of the blood vessels belonging to different organs in salt-sensitive and salt-resistant Dahl-strain rats].
Topics: Adrenergic Fibers; Animals; Blood Vessels; Hypertension; Male; Oxidopamine; Rats; Rats, Inbred Strai | 1996 |
Hypertension caused by chronic intermittent hypoxia--influence of chemoreceptors and sympathetic nervous system.
Topics: Adrenal Medulla; Animals; Blood Pressure; Carotid Body; Catecholamines; Chemoreceptor Cells; Chronic | 1997 |
Cocaine-induced hypertension: role of the peripheral sympathetic system.
Topics: Adrenergic Agents; Adrenergic alpha-Antagonists; Animals; Blood Pressure; Carotid Arteries; Cocaine; | 1999 |
A possible indirect sympathomimetic action of metformin in the arterial vessel wall of spontanously hypertensive rats.
Topics: Animals; Antidepressive Agents; Arteries; Autonomic Fibers, Postganglionic; Desipramine; Drug Intera | 2001 |
Angiotensin converting enzyme inhibition prevents trophic and hypertensive effects of an antagonist of adenosine receptors.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Arteries; Blood Pressure; Body Weight; Captopril; | 2002 |
Inhibition by 6-hydroxydopamine of enhanced gastric carcinogenesis induced by N-methyl-N'-nitro-N-nitrosoguanidine in spontaneously hypertensive rats.
Topics: Animals; DNA; Gastric Mucosa; Hydrogen-Ion Concentration; Hypertension; Methylnitronitrosoguanidine; | 1992 |
Role of the sympathetic nervous system in the onset of hypertension in the rat: the effect of 6-OH-dopamine.
Topics: Adrenocorticotropic Hormone; Animals; Blood Pressure; Hydroxydopamines; Hypertension; Male; Oxidopam | 1991 |
Effects of aging and drugs on myocardial beta-adrenergic receptors in M-SHRSP and SHRSP.
Topics: 5'-Nucleotidase; Aging; Animals; Cardiomegaly; Cerebrovascular Disorders; Disease Susceptibility; Do | 1991 |
Enhanced norepinephrine release in hypothalamus from locus coeruleus in SHR.
Topics: Animals; Blood Pressure; Glutamates; Glutamic Acid; Hydroxydopamines; Hypertension; Hypothalamus; Lo | 1991 |
[Central norepinephrine and angiotensin II contents in the brain regions of spontaneously hypertensive rats (SHR) and the interaction between them].
Topics: Angiotensin II; Animals; Blood Pressure; Brain; Captopril; Hypertension; Norepinephrine; Oxidopamine | 1991 |
Chemical sympathectomy alters the development of hypertension in miniature swine.
Topics: Animals; Blood Pressure; Body Weight; Catecholamines; Desoxycorticosterone; Female; Hydroxydopamines | 1991 |
Acute renal function in chronically sympathectomized deoxycorticosterone acetate-treated miniature swine.
Topics: Animals; Blood Pressure; Desoxycorticosterone; Female; Hydroxydopamines; Hypertension; Kidney; Male; | 1991 |
Effect of chemical sympathectomy on cerebral blood flow in rats.
Topics: Animals; Brain Edema; Cerebral Arteries; Cerebrovascular Circulation; Homeostasis; Hypertension; Mal | 1991 |
Effects of 6-hydroxydopamine in hypertensive adult miniature swine.
Topics: Animals; Behavior, Animal; Blood Pressure; Desoxycorticosterone; Female; Hydroxydopamines; Hypertens | 1990 |
Lesions of the ventral noradrenergic bundle prevent the rise in blood pressure induced by social deprivation stress in the rat.
Topics: Animals; Dopamine; Epinephrine; Hydroxydopamines; Hypertension; Hypothalamus; Male; Norepinephrine; | 1990 |
Autoradiography of dopamine receptors and dopamine uptake sites in the spontaneously hypertensive rat.
Topics: Animals; Autoradiography; Benzazepines; Brain; Dopamine; Hydroxydopamines; Hypertension; Mazindol; O | 1990 |
Transmission of hypertension in rats by cross circulation.
Topics: Animals; Antibodies; Cross Circulation; Digoxin; Hydroxydopamines; Hypertension; Male; Oxidopamine; | 1989 |
Angiotensin converting enzyme activity in the amygdaloid complex in a neurogenic hypertensive model.
Topics: Amygdala; Animals; Hydroxydopamines; Hypertension; Male; Neural Pathways; Norepinephrine; Oxidopamin | 1988 |
Mechanism of action of vasoconstrictor responses to atriopeptin II in conscious SHR.
Topics: Animals; Atrial Natriuretic Factor; Blood Pressure; Heart Rate; Hydroxydopamines; Hypertension; Kidn | 1985 |
Effect of captopril on converting enzyme activity in chemically sympathectomized, spontaneously hypertensive rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Hydroxydopamines; Hype | 1985 |
Brain dopamine depletion by lesions in the substantia nigra attenuates the development of hypertension in the spontaneously hypertensive rat.
Topics: Animals; Brain; Dopamine; Hydroxydopamines; Hypertension; Injections, Intraventricular; Male; Norepi | 1986 |
Diminished beta-adrenoceptor-mediated relaxation of arteries from spontaneously hypertensive rats before and during development of hypertension.
Topics: Albuterol; Animals; Arteries; Dinoprost; Hydroxydopamines; Hypertension; Isoproterenol; Male; Nitrop | 1987 |
Increased beta 2-adrenoreceptor density in heart, kidney and lung of spontaneously hypertensive rats.
Topics: Animals; Hydroxydopamines; Hypertension; In Vitro Techniques; Iodocyanopindolol; Kidney; Kinetics; L | 1987 |
Central 6-OHDA affects both open-field exploratory behaviour and the development of hypertension in SHR.
Topics: Animals; Blood Pressure; Brain Chemistry; Catecholamines; Exploratory Behavior; Heart Rate; Hydroxyd | 1986 |
Relative importance of sympathetic nerves and of circulating adrenaline and vasopressin in mediating hypertension after lesions of the caudal ventrolateral medulla in the rat.
Topics: Adrenalectomy; Analysis of Variance; Animals; Blood Pressure; Brain; Epinephrine; Heart Rate; Hydrox | 1986 |
Brain noradrenaline and the development of hypertension: the effect of treatment with central 6-hydroxydopamine or DSP-4.
Topics: Animals; Benzylamines; Brain Chemistry; Catecholamines; Hydroxydopamines; Hypertension; Male; Neurot | 1986 |
Neonatal sympathectomy of normotensive Wistar-Kyoto and spontaneously hypertensive rats with 6-hydroxydopamine: effects on resistance vessel structure and sensitivity to calcium.
Topics: Animals; Calcium; Hydroxydopamines; Hypertension; Oxidopamine; Rats; Rats, Inbred SHR; Rats, Inbred | 1986 |
Increased non-collagen protein synthesis in the posterior cerebral artery in spontaneously hypertensive rats.
Topics: Animals; Cerebral Arteries; Clonidine; Hydroxydopamines; Hypertension; Male; Oxidopamine; Proline; P | 1986 |
Central 6-hydroxydopamine and renal sodium retention in mineralocorticoid-treated rats.
Topics: Animals; Desoxycorticosterone; Hydroxydopamines; Hypertension; Injections, Intraventricular; Kidney; | 1986 |
Effects of 6-hydroxydopamine and the PNMT inhibitor LY134046 on pressor responses to stimulation of the subretrofacial nucleus in anaesthetized stroke-prone spontaneously hypertensive rats.
Topics: Anesthesia; Animals; Benzazepines; Blood Pressure; Cerebrovascular Disorders; Disease Susceptibility | 1987 |
Cerebrovascular permeability to horseradish peroxidase in hypertensive rats: effects of unilateral locus ceruleus lesion.
Topics: Animals; Arterioles; Blood Pressure; Blood-Brain Barrier; Brain; Capillary Permeability; Horseradish | 1987 |
Abnormalities in hypothalamic and neurohypophysial vasopressin content are not a consequence of hypertension in the spontaneously hypertensive rat.
Topics: Animals; Blood Pressure; Brain; Captopril; Catecholamines; Hydroxydopamines; Hypertension; Hypothala | 1988 |
Receptor adaptive responsiveness in disease models: 6-OHDA lesioned and spontaneously hypertensive rats.
Topics: Animals; Brain Chemistry; Disease Models, Animal; Dopamine; Hydroxydopamines; Hypertension; Male; No | 1988 |
Central noradrenergic neurons and the hypertensive effects of intracerebroventricularly administered prostaglandin E2 in anaesthetized rabbits.
Topics: Animals; Blood Pressure; Cerebral Ventricles; Dinoprostone; Female; Heart Rate; Hydroxydopamines; Hy | 1985 |
Cerebral intraventricular 6-hydroxydopamine prevents vascular changes in the mineralocorticoid hypertensive rat.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Blood Pressure; Cerebral Ventricles; Desoxycorticoster | 1985 |