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oxidopamine and Blood Pressure, High

oxidopamine has been researched along with Blood Pressure, High in 58 studies

Oxidopamine: A neurotransmitter analogue that depletes noradrenergic stores in nerve endings and induces a reduction of dopamine levels in the brain. Its mechanism of action is related to the production of cytolytic free-radicals.
oxidopamine : A benzenetriol that is phenethylamine in which the hydrogens at positions 2, 4, and 5 on the phenyl ring are replaced by hydroxy groups. It occurs naturally in human urine, but is also produced as a metabolite of the drug DOPA (used for the treatment of Parkinson's disease).

Research Excerpts

ExcerptRelevanceReference
"Cocaine causes hypertension at least in part by stimulating the sympathetic nervous system, but it is not clear if this effect is centrally or peripherally mediated."7.70Cocaine-induced hypertension: role of the peripheral sympathetic system. ( Arruda, JA; Dunea, G; Mo, W; Singh, AK, 1999)
" To assess whether these differential structural effects do translate into different effects on LV function and on heart failure mortality, Bd or sham Bd 8-week-old rats were randomized to vehicle treatment (Vh), chemical sympathectomy ([Sx] 6-hydroxydopamine, 150 mg/kg IP twice a week), beta-adrenoceptor blockade (propranolol [Pro], 40 mg/kg per day PO), or alpha-adrenoceptor blockade (doxazosin [Dox], 5 mg/kg per day PO)."3.73Survival benefits of different antiadrenergic interventions in pressure overload left ventricular hypertrophy/failure. ( Busca, G; Cesana, F; Clari, F; Ferrari, AU; Ferrero, I; Gatti, C; Janetti, MB; Mancia, G; Palladini, G; Perlini, S; Tozzi, R; Vezzoli, M, 2006)
"Cocaine causes hypertension at least in part by stimulating the sympathetic nervous system, but it is not clear if this effect is centrally or peripherally mediated."3.70Cocaine-induced hypertension: role of the peripheral sympathetic system. ( Arruda, JA; Dunea, G; Mo, W; Singh, AK, 1999)
" The effects of isoproterenol (ISP) and chemical sympathectomy (6-hydroxydopamine treatment) on myocardial beta-receptors were also investigated in 10 and 24 week-old SHRS and WKY to examine the effects of hypertension and aging on receptor regulation."3.68Effects of aging and drugs on myocardial beta-adrenergic receptors in M-SHRSP and SHRSP. ( Ikawa, H; Suzuki, A, 1991)
" The potency and efficacy of isoproterenol (ISO) in these arteries were decreased in SHR before and during the development of hypertension as compared with age-matched Wistar Kyoto rats (WKY)."3.67Diminished beta-adrenoceptor-mediated relaxation of arteries from spontaneously hypertensive rats before and during development of hypertension. ( Aoki, K; Asano, M; Dohi, Y; Fujimoto, S; Matsuda, T, 1987)
"To study the possible influence of sympathetic adrenergic tone on the blood-brain barrier function during acute hypertension in conscious unrestrained rats with indwelling catheters in the aorta and a jugular vein the blood pressure was increase by noradrenaline, 6-hydroxydopamine (6-OHDA) or baclofen."3.66Neurogenic modification of the vulnerability of the blood-brain barrier during acute hypertension in conscious rats. ( Auer, LM; Johansson, BB, 1983)
" However, it is also known to accumulate in various tissues up to several times higher after standard oral dosing and we now have evidence from both in vivo and in vitro experiments with spontaneously hypertensive rats (SHR) that millimolar levels stimulate release of norepinephrine (NE) from vascular sympathetic nerve endings (SNEs)."1.31A possible indirect sympathomimetic action of metformin in the arterial vessel wall of spontanously hypertensive rats. ( Lee, JM; Peuler, JD, 2001)
"Captopril was given (30 or 100 mg kg(-l) day(-l); p."1.31Angiotensin converting enzyme inhibition prevents trophic and hypertensive effects of an antagonist of adenosine receptors. ( Albino-Teixeira, A; Morato, M; Sousa, T, 2002)
"Our data imply that repetitive hypoxemia in SAS is probably the cause of the high prevalence of systemic hypertension in this population and that peripheral chemoreceptors and the sympathetic nervous system play important roles in this pathophysiologic process."1.30Hypertension caused by chronic intermittent hypoxia--influence of chemoreceptors and sympathetic nervous system. ( Bao, G; Fletcher, EC; Lesske, J; Unger, T, 1997)
"In control group (WKY rat + NaCl), gastric cancers were found in 2 (11%) of 18 rats examined in week 52."1.28Inhibition by 6-hydroxydopamine of enhanced gastric carcinogenesis induced by N-methyl-N'-nitro-N-nitrosoguanidine in spontaneously hypertensive rats. ( Baba, M; Iishi, H; Taniguchi, H; Tatsuta, M, 1992)
"In fetal sheep, hypoxemia causes arterial hypertension, bradycardia, a redistribution of blood flow, and an increase in plasma vasopressin and catecholamine concentrations."1.27Circulatory and humoral responses of sympathectomized fetal sheep to hypoxemia. ( Iwamoto, HS; Keil, LC; Mirkin, BL; Rudolph, AM, 1983)
"We suggest that A1 hypertension is predominantly mediated through increased activity of sympathetic vasoconstrictor nerves, and that circulating adrenaline and vasopressin only make a minor contribution to the increase in pressure."1.27Hypertension after brainstem (A1) lesions in normal rats and in rats with adrenalectomy, sympathectomy or diabetes insipidus. ( Cain, M; Chalmers, J; Kapoor, V; Minson, J, 1984)
" The mesenteric arteries from all three types of hypertensive rats showed an increased reactivity to noradrenaline as characterized by a steeper dose-response curve and elevated maximal vasoconstriction when compared with normotensive controls."1.27Vascular reactivity of rats after prevention of hypertension by central administration of 6-hydroxydopamine. ( Haeusler, G, 1984)
"The captopril-treated rats had a significant elevation in serum renin activity at 12 weeks of age indicating the presence of chronic converting enzyme inhibition, and the 6-OHDA-treatment resulted in a depletion of hypothalamic (86%) and brainstem (76%) norepinephrine content."1.27Abnormalities in hypothalamic and neurohypophysial vasopressin content are not a consequence of hypertension in the spontaneously hypertensive rat. ( Aravich, PF; Blair, ML; Devine, MA; Felten, SY; Sladek, CD, 1988)
" Dose-response curves to serotonin were shifted to the left in femoral arteries from DOCA-treated rats compared to both control and 6-OHDA-DOCA-treated rats (ED50: DOCA = 6."1.27Cerebral intraventricular 6-hydroxydopamine prevents vascular changes in the mineralocorticoid hypertensive rat. ( Hall, JL; Lamb, FS; Mecca, TE; Webb, RC, 1985)
" 6-OH-DA in the dosage applied, induces during its time of action in NR a smaller, in SHR a larger decrease of blood pressure and, presumably induced by intense NA-depletion of the myocardium, myocardial alterations."1.26[Functional and structural behavior of the cardiovascular system of normotonic and spontaneously hypertensive rats following chemical sympathectomy and angiotensin administration]. ( Becker, CH; Engler, E; Matthias, D; Moritz, V; Schmidt, R; Will-Shahab, L, 1981)

Research

Studies (58)

TimeframeStudies, this research(%)All Research%
pre-199036 (62.07)18.7374
1990's16 (27.59)18.2507
2000's4 (6.90)29.6817
2010's2 (3.45)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Banegas, I2
Prieto, I2
Vives, F2
Alba, F2
de Gasparo, M2
Duran, R2
Luna, Jde D1
Segarra, AB2
Hermoso, F1
Ramírez, M1
Luna, JD1
Wangesteen, R1
Ruiz-Bailén, M1
Ramírez-Sánchez, M1
Chaswal, M1
Das, S1
Prasad, J1
Katyal, A1
Fahim, M1
Perlini, S1
Ferrero, I1
Palladini, G1
Tozzi, R1
Gatti, C1
Vezzoli, M1
Cesana, F1
Janetti, MB1
Clari, F1
Busca, G1
Mancia, G1
Ferrari, AU1
Takahashi, H1
Inoue, A1
Takeda, K2
Okajima, H1
Sasaki, S2
Yoshimura, M1
Nakagawa, M2
Ijichi, H1
U'Prichard, DC1
Dadkar, NK1
Aroskar, VA1
Gupte, RD1
Dohadwalla, AN1
Howes, LG1
Kubo, T1
Misu, Y1
Chatelain, P2
Robberecht, P2
Camus, JC1
De Neef, P1
Waelbroeck, M2
Roba, J2
Christophe, J2
Bloom, FE1
Baetge, G1
Deyo, S1
Ettenberg, A1
Koda, L1
Magistretti, PJ1
Shoemaker, WJ1
Staunton, DA1
Huu, AN1
Johansson, BB2
Auer, LM1
Iwamoto, HS1
Rudolph, AM1
Mirkin, BL1
Keil, LC1
van den Buuse, M4
de Kloet, ER1
Versteeg, DH3
de Jong, W4
Rodionov, IM1
Markov, KhM1
Pinelis, VG1
Kozlov, AV1
Koshelev, VB1
Chalmers, J2
Minson, J2
Kapoor, V2
Cain, M2
Haeusler, G1
Ben-Menachem, E1
Svensson, TH1
Matthias, D1
Moritz, V1
Engler, E1
Will-Shahab, L1
Schmidt, R1
Becker, CH1
Lin, MT2
Yang, JJ1
Chu, TF1
Leont'eva, GR1
Zicha, J1
Kunes, J1
Lesske, J1
Fletcher, EC1
Bao, G1
Unger, T1
Mo, W1
Arruda, JA1
Dunea, G1
Singh, AK1
Lee, JM1
Peuler, JD1
Sousa, T1
Morato, M1
Albino-Teixeira, A1
Tatsuta, M1
Iishi, H1
Baba, M1
Taniguchi, H1
Li, M1
Whitworth, JA1
Ikawa, H1
Suzuki, A1
Kawasaki, S1
Tanaka, M1
Itoh, H1
Hirata, M1
Nakata, T1
Hayashi, J1
Oguro, M1
Yang, K1
Ding, H1
Zhou, Q1
Luo, HY1
Wu, ZY1
Thomas, GD3
O'Hagan, KP2
Zambraski, EJ3
Kobayashi, H1
Hayashi, M1
Kawano, H1
Handa, Y1
Kabuto, M1
Ide, H1
Montero, S1
Fuentes, JA1
Fernandez-Tome, P1
Kujirai, K1
Przedborski, S1
Kostic, V1
Jackson-Lewis, V1
Fahn, S1
Cadet, JL1
Zidek, W1
Ottens, E1
Heckmann, U1
Dabsys, SM1
Balda, MS1
Pirola, CJ1
Finkielman, S1
Nahmod, VE1
Lappe, RW1
Todt, JA1
Wendt, RL1
Schwartz, D1
Katsube, NC1
Needleman, P1
Sattar, MA1
Latiff, A1
Gan, EK1
Fujimoto, S1
Dohi, Y1
Aoki, K1
Asano, M1
Matsuda, T1
Michel, MC1
Wang, XL1
Schlicker, E1
Göthert, M1
Beckeringh, JJ1
Brodde, OE1
Veldhuis, HD1
de Boer, S1
Caon, A1
Versteeq, DH1
Nyborg, NC1
Korsgaard, N1
Mulvany, MJ1
Nakada, T1
Kimura, M1
Watanabe, H1
Yamori, Y1
Lovenberg, W1
Hall, JL2
Mecca, TE2
Malvin, RL1
Webb, RC2
Head, GA1
Howe, PR1
Nag, S1
Harik, SI1
Sladek, CD1
Devine, MA1
Felten, SY1
Aravich, PF1
Blair, ML1
Caccia, C1
Achilli, G1
Buonamici, M1
Carpentieri, M1
Cervini, MA1
Maj, R1
Pegrassi, L1
Rossi, AC1
Otorii, T1
Ohkubo, K1
Suzuki, K1
Lamb, FS1

Reviews

4 reviews available for oxidopamine and Blood Pressure, High

ArticleYear
Biochemical characteristics and regulation of brain alpha 2-adrenoceptors.
    Annals of the New York Academy of Sciences, 1984, Volume: 430

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brain; Clonidine; Epinephrine; Hum

1984
Central catecholaminergic neurones and spontaneously hypertensive rats.
    Journal of autonomic pharmacology, 1984, Volume: 4, Issue:3

    Topics: Animals; Blood Pressure; Brain; Brain Chemistry; Catecholamines; Dopamine beta-Hydroxylase; Hydroxyd

1984
Chemical and physiological aspects of the actions of lithium and antidepressant drugs.
    Neuropharmacology, 1983, Volume: 22, Issue:3 Spec No

    Topics: Animals; Antidepressive Agents; Apomorphine; Blood Pressure; Brain Chemistry; Diet; Endorphins; Halo

1983
Atriopeptins in fluid and electrolyte homeostasis.
    Federation proceedings, 1986, Volume: 45, Issue:9

    Topics: Animals; Atrial Natriuretic Factor; Blood Volume; Deamino Arginine Vasopressin; Dogs; Hydroxydopamin

1986

Other Studies

54 other studies available for oxidopamine and Blood Pressure, High

ArticleYear
Asymmetrical response of aminopeptidase A and nitric oxide in plasma of normotensive and hypertensive rats with experimental hemiparkinsonism.
    Neuropharmacology, 2009, Volume: 56, Issue:3

    Topics: Animals; Blood Pressure; Corpus Striatum; Functional Laterality; Glutamyl Aminopeptidase; Hypertensi

2009
Blood pressure increased dramatically in hypertensive rats after left hemisphere lesions with 6-hydroxydopamine.
    Neuroscience letters, 2011, Aug-15, Volume: 500, Issue:2

    Topics: Animals; Blood Pressure; Corpus Striatum; Functional Laterality; Heart Rate; Hypertension; Male; Oxi

2011
Cardiac autonomic function in acutely nitric oxide deficient hypertensive rats: role of the sympathetic nervous system and oxidative stress.
    Canadian journal of physiology and pharmacology, 2011, Volume: 89, Issue:12

    Topics: Animals; Baroreflex; Heart; Heart Rate; Hypertension; Male; NG-Nitroarginine Methyl Ester; Nitric Ox

2011
Survival benefits of different antiadrenergic interventions in pressure overload left ventricular hypertrophy/failure.
    Hypertension (Dallas, Tex. : 1979), 2006, Volume: 48, Issue:1

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Aorta, Abdominal; Blood Pressure

2006
Augmented central cholinergic mechanisms in spontaneously hypertensive rats. Involvement of deranged noradrenergic mechanisms in the brain.
    Japanese heart journal, 1984, Volume: 25, Issue:3

    Topics: Animals; Blood Pressure; Brain; Carbachol; Heart Rate; Hemodynamics; Hydroxydopamines; Hypertension;

1984
Central pressor activity of cimetidine in spontaneously hypertensive rats.
    The Journal of pharmacy and pharmacology, 1984, Volume: 36, Issue:7

    Topics: Animals; Blood Pressure; Brain; Cimetidine; Hydroxydopamines; Hypertension; Male; Norepinephrine; Ox

1984
Anti-hypertensive effects of propranolol unaltered by 6-hydroxydopamine given intraventricularly to SHR.
    Japanese journal of pharmacology, 1981, Volume: 31, Issue:2

    Topics: Animals; Blood Pressure; Brain; Female; Heart Rate; Hydroxydopamines; Hypertension; Injections, Intr

1981
The adenylate cyclase activity in heart membranes from normotensive and spontaneously hypertensive rats, after chemical sympathectomy, suggests the presence of presynaptic secretin receptors.
    European journal of pharmacology, 1983, Sep-30, Volume: 93, Issue:3-4

    Topics: Adenylyl Cyclases; Animals; Blood Pressure; Body Weight; Heart; Heart Rate; Hydroxydopamines; Hypert

1983
Effects of a chemical sympathectomy on cardiac muscarinic receptors in normotensive (WKY) and spontaneously hypertensive (SHR) rats.
    Biochemical pharmacology, 1983, Jun-01, Volume: 32, Issue:11

    Topics: Animals; Heart Rate; Hydroxydopamines; Hypertension; Male; Muscarinic Antagonists; Oxidopamine; Rats

1983
Neurogenic modification of the vulnerability of the blood-brain barrier during acute hypertension in conscious rats.
    Acta physiologica Scandinavica, 1983, Volume: 117, Issue:4

    Topics: Adrenergic Fibers; Animals; Baclofen; Blood-Brain Barrier; Carbon Dioxide; Clonidine; Hydroxydopamin

1983
Circulatory and humoral responses of sympathectomized fetal sheep to hypoxemia.
    The American journal of physiology, 1983, Volume: 245, Issue:5 Pt 1

    Topics: Animals; Blood Pressure; Dopamine; Female; Fetus; Heart; Heart Rate; Hemoglobins; Hydroxydopamines;

1983
Regional brain catecholamine levels and the development of hypertension in the spontaneously hypertensive rat: the effect of 6-hydroxydopamine.
    Brain research, 1984, Jun-03, Volume: 301, Issue:2

    Topics: Animals; Blood Pressure; Brain; Brain Mapping; Catecholamines; Caudate Nucleus; Dopamine; Epinephrin

1984
[Role of sympathetic nervous system in the pathogenesis of spontaneous hypertension in rats].
    Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova, 1984, Volume: 70, Issue:6

    Topics: Animals; Arteries; Blood Pressure; Cardiac Output; Guanethidine; Hindlimb; Hydroxydopamines; Hyperte

1984
Hypertension after brainstem (A1) lesions in normal rats and in rats with adrenalectomy, sympathectomy or diabetes insipidus.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1984, Volume: 2, Issue:3

    Topics: Adrenal Glands; Adrenalectomy; Animals; Arginine Vasopressin; Brain Stem; Diabetes Insipidus; Epinep

1984
Vascular reactivity of rats after prevention of hypertension by central administration of 6-hydroxydopamine.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1984, Volume: 2, Issue:3

    Topics: Animals; Desoxycorticosterone; Hydroxydopamines; Hypertension; In Vitro Techniques; Injections, Intr

1984
Increased vulnerability of the blood-brain barrier to acute hypertension following depletion of brain noradrenaline.
    Journal of neural transmission, 1982, Volume: 53, Issue:2-3

    Topics: Acute Disease; Animals; Blood-Brain Barrier; Brain Chemistry; Hydroxydopamines; Hypertension; Male;

1982
[Functional and structural behavior of the cardiovascular system of normotonic and spontaneously hypertensive rats following chemical sympathectomy and angiotensin administration].
    Acta biologica et medica Germanica, 1981, Volume: 40, Issue:12

    Topics: Angiotensin II; Animals; Blood Circulation; Coronary Circulation; Hydroxydopamines; Hypertension; Ma

1981
Stimulation of the nigrostriatal dopamine system produces hypertension and tachycardia in rats.
    The American journal of physiology, 1994, Volume: 266, Issue:6 Pt 2

    Topics: Animals; Cardiovascular Physiological Phenomena; Cardiovascular System; Corpus Striatum; Dopamine; D

1994
Picrotoxin induces both hypertension and dopamine release in the rat amygdala.
    Neuroscience letters, 1996, Nov-08, Volume: 218, Issue:3

    Topics: Amygdala; Animals; Anticonvulsants; Cardiovascular System; Convulsants; Diazepam; Dopamine; Dopamine

1996
[The effect of chemical sympathectomy on the adrenergic innervation of the blood vessels belonging to different organs in salt-sensitive and salt-resistant Dahl-strain rats].
    Morfologiia (Saint Petersburg, Russia), 1996, Volume: 110, Issue:4

    Topics: Adrenergic Fibers; Animals; Blood Vessels; Hypertension; Male; Oxidopamine; Rats; Rats, Inbred Strai

1996
Hypertension caused by chronic intermittent hypoxia--influence of chemoreceptors and sympathetic nervous system.
    Journal of hypertension, 1997, Volume: 15, Issue:12 Pt 2

    Topics: Adrenal Medulla; Animals; Blood Pressure; Carotid Body; Catecholamines; Chemoreceptor Cells; Chronic

1997
Cocaine-induced hypertension: role of the peripheral sympathetic system.
    Pharmacological research, 1999, Volume: 40, Issue:2

    Topics: Adrenergic Agents; Adrenergic alpha-Antagonists; Animals; Blood Pressure; Carotid Arteries; Cocaine;

1999
A possible indirect sympathomimetic action of metformin in the arterial vessel wall of spontanously hypertensive rats.
    Life sciences, 2001, Jul-20, Volume: 69, Issue:9

    Topics: Animals; Antidepressive Agents; Arteries; Autonomic Fibers, Postganglionic; Desipramine; Drug Intera

2001
Angiotensin converting enzyme inhibition prevents trophic and hypertensive effects of an antagonist of adenosine receptors.
    European journal of pharmacology, 2002, Apr-19, Volume: 441, Issue:1-2

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Arteries; Blood Pressure; Body Weight; Captopril;

2002
Inhibition by 6-hydroxydopamine of enhanced gastric carcinogenesis induced by N-methyl-N'-nitro-N-nitrosoguanidine in spontaneously hypertensive rats.
    International journal of cancer, 1992, Nov-11, Volume: 52, Issue:5

    Topics: Animals; DNA; Gastric Mucosa; Hydrogen-Ion Concentration; Hypertension; Methylnitronitrosoguanidine;

1992
Role of the sympathetic nervous system in the onset of hypertension in the rat: the effect of 6-OH-dopamine.
    Clinical and experimental pharmacology & physiology, 1991, Volume: 18, Issue:4

    Topics: Adrenocorticotropic Hormone; Animals; Blood Pressure; Hydroxydopamines; Hypertension; Male; Oxidopam

1991
Effects of aging and drugs on myocardial beta-adrenergic receptors in M-SHRSP and SHRSP.
    Clinical and experimental hypertension. Part A, Theory and practice, 1991, Volume: 13, Issue:5

    Topics: 5'-Nucleotidase; Aging; Animals; Cardiomegaly; Cerebrovascular Disorders; Disease Susceptibility; Do

1991
Enhanced norepinephrine release in hypothalamus from locus coeruleus in SHR.
    Japanese heart journal, 1991, Volume: 32, Issue:2

    Topics: Animals; Blood Pressure; Glutamates; Glutamic Acid; Hydroxydopamines; Hypertension; Hypothalamus; Lo

1991
[Central norepinephrine and angiotensin II contents in the brain regions of spontaneously hypertensive rats (SHR) and the interaction between them].
    Sheng li xue bao : [Acta physiologica Sinica], 1991, Volume: 43, Issue:4

    Topics: Angiotensin II; Animals; Blood Pressure; Brain; Captopril; Hypertension; Norepinephrine; Oxidopamine

1991
Chemical sympathectomy alters the development of hypertension in miniature swine.
    Hypertension (Dallas, Tex. : 1979), 1991, Volume: 17, Issue:3

    Topics: Animals; Blood Pressure; Body Weight; Catecholamines; Desoxycorticosterone; Female; Hydroxydopamines

1991
Acute renal function in chronically sympathectomized deoxycorticosterone acetate-treated miniature swine.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1991, Volume: 197, Issue:3

    Topics: Animals; Blood Pressure; Desoxycorticosterone; Female; Hydroxydopamines; Hypertension; Kidney; Male;

1991
Effect of chemical sympathectomy on cerebral blood flow in rats.
    Journal of neurosurgery, 1991, Volume: 75, Issue:6

    Topics: Animals; Brain Edema; Cerebral Arteries; Cerebrovascular Circulation; Homeostasis; Hypertension; Mal

1991
Effects of 6-hydroxydopamine in hypertensive adult miniature swine.
    Clinical and experimental hypertension. Part A, Theory and practice, 1990, Volume: 12, Issue:4

    Topics: Animals; Behavior, Animal; Blood Pressure; Desoxycorticosterone; Female; Hydroxydopamines; Hypertens

1990
Lesions of the ventral noradrenergic bundle prevent the rise in blood pressure induced by social deprivation stress in the rat.
    Cellular and molecular neurobiology, 1990, Volume: 10, Issue:4

    Topics: Animals; Dopamine; Epinephrine; Hydroxydopamines; Hypertension; Hypothalamus; Male; Norepinephrine;

1990
Autoradiography of dopamine receptors and dopamine uptake sites in the spontaneously hypertensive rat.
    Brain research bulletin, 1990, Volume: 25, Issue:5

    Topics: Animals; Autoradiography; Benzazepines; Brain; Dopamine; Hydroxydopamines; Hypertension; Mazindol; O

1990
Transmission of hypertension in rats by cross circulation.
    Hypertension (Dallas, Tex. : 1979), 1989, Volume: 14, Issue:1

    Topics: Animals; Antibodies; Cross Circulation; Digoxin; Hydroxydopamines; Hypertension; Male; Oxidopamine;

1989
Angiotensin converting enzyme activity in the amygdaloid complex in a neurogenic hypertensive model.
    Clinical and experimental hypertension. Part A, Theory and practice, 1988, Volume: 10, Issue:4

    Topics: Amygdala; Animals; Hydroxydopamines; Hypertension; Male; Neural Pathways; Norepinephrine; Oxidopamin

1988
Mechanism of action of vasoconstrictor responses to atriopeptin II in conscious SHR.
    The American journal of physiology, 1985, Volume: 249, Issue:6 Pt 2

    Topics: Animals; Atrial Natriuretic Factor; Blood Pressure; Heart Rate; Hydroxydopamines; Hypertension; Kidn

1985
Effect of captopril on converting enzyme activity in chemically sympathectomized, spontaneously hypertensive rats.
    Japanese journal of pharmacology, 1985, Volume: 39, Issue:3

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Hydroxydopamines; Hype

1985
Brain dopamine depletion by lesions in the substantia nigra attenuates the development of hypertension in the spontaneously hypertensive rat.
    Brain research, 1986, Mar-12, Volume: 368, Issue:1

    Topics: Animals; Brain; Dopamine; Hydroxydopamines; Hypertension; Injections, Intraventricular; Male; Norepi

1986
Diminished beta-adrenoceptor-mediated relaxation of arteries from spontaneously hypertensive rats before and during development of hypertension.
    European journal of pharmacology, 1987, Apr-14, Volume: 136, Issue:2

    Topics: Albuterol; Animals; Arteries; Dinoprost; Hydroxydopamines; Hypertension; Isoproterenol; Male; Nitrop

1987
Increased beta 2-adrenoreceptor density in heart, kidney and lung of spontaneously hypertensive rats.
    Journal of autonomic pharmacology, 1987, Volume: 7, Issue:1

    Topics: Animals; Hydroxydopamines; Hypertension; In Vitro Techniques; Iodocyanopindolol; Kidney; Kinetics; L

1987
Central 6-OHDA affects both open-field exploratory behaviour and the development of hypertension in SHR.
    Pharmacology, biochemistry, and behavior, 1986, Volume: 24, Issue:1

    Topics: Animals; Blood Pressure; Brain Chemistry; Catecholamines; Exploratory Behavior; Heart Rate; Hydroxyd

1986
Relative importance of sympathetic nerves and of circulating adrenaline and vasopressin in mediating hypertension after lesions of the caudal ventrolateral medulla in the rat.
    Journal of hypertension, 1986, Volume: 4, Issue:3

    Topics: Adrenalectomy; Analysis of Variance; Animals; Blood Pressure; Brain; Epinephrine; Heart Rate; Hydrox

1986
Brain noradrenaline and the development of hypertension: the effect of treatment with central 6-hydroxydopamine or DSP-4.
    Clinical and experimental pharmacology & physiology, 1986, Volume: 13, Issue:6

    Topics: Animals; Benzylamines; Brain Chemistry; Catecholamines; Hydroxydopamines; Hypertension; Male; Neurot

1986
Neonatal sympathectomy of normotensive Wistar-Kyoto and spontaneously hypertensive rats with 6-hydroxydopamine: effects on resistance vessel structure and sensitivity to calcium.
    Journal of hypertension, 1986, Volume: 4, Issue:4

    Topics: Animals; Calcium; Hydroxydopamines; Hypertension; Oxidopamine; Rats; Rats, Inbred SHR; Rats, Inbred

1986
Increased non-collagen protein synthesis in the posterior cerebral artery in spontaneously hypertensive rats.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1986, Volume: 4, Issue:3

    Topics: Animals; Cerebral Arteries; Clonidine; Hydroxydopamines; Hypertension; Male; Oxidopamine; Proline; P

1986
Central 6-hydroxydopamine and renal sodium retention in mineralocorticoid-treated rats.
    Canadian journal of physiology and pharmacology, 1986, Volume: 64, Issue:12

    Topics: Animals; Desoxycorticosterone; Hydroxydopamines; Hypertension; Injections, Intraventricular; Kidney;

1986
Effects of 6-hydroxydopamine and the PNMT inhibitor LY134046 on pressor responses to stimulation of the subretrofacial nucleus in anaesthetized stroke-prone spontaneously hypertensive rats.
    Journal of the autonomic nervous system, 1987, Volume: 18, Issue:3

    Topics: Anesthesia; Animals; Benzazepines; Blood Pressure; Cerebrovascular Disorders; Disease Susceptibility

1987
Cerebrovascular permeability to horseradish peroxidase in hypertensive rats: effects of unilateral locus ceruleus lesion.
    Acta neuropathologica, 1987, Volume: 73, Issue:3

    Topics: Animals; Arterioles; Blood Pressure; Blood-Brain Barrier; Brain; Capillary Permeability; Horseradish

1987
Abnormalities in hypothalamic and neurohypophysial vasopressin content are not a consequence of hypertension in the spontaneously hypertensive rat.
    Brain research, 1988, Mar-29, Volume: 445, Issue:1

    Topics: Animals; Blood Pressure; Brain; Captopril; Catecholamines; Hydroxydopamines; Hypertension; Hypothala

1988
Receptor adaptive responsiveness in disease models: 6-OHDA lesioned and spontaneously hypertensive rats.
    Journal of receptor research, 1988, Volume: 8, Issue:1-4

    Topics: Animals; Brain Chemistry; Disease Models, Animal; Dopamine; Hydroxydopamines; Hypertension; Male; No

1988
Central noradrenergic neurons and the hypertensive effects of intracerebroventricularly administered prostaglandin E2 in anaesthetized rabbits.
    Prostaglandins, 1985, Volume: 29, Issue:1

    Topics: Animals; Blood Pressure; Cerebral Ventricles; Dinoprostone; Female; Heart Rate; Hydroxydopamines; Hy

1985
Cerebral intraventricular 6-hydroxydopamine prevents vascular changes in the mineralocorticoid hypertensive rat.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1985, Volume: 179, Issue:2

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Blood Pressure; Cerebral Ventricles; Desoxycorticoster

1985