oxidopamine has been researched along with Bipolar Disorder in 2 studies
Oxidopamine: A neurotransmitter analogue that depletes noradrenergic stores in nerve endings and induces a reduction of dopamine levels in the brain. Its mechanism of action is related to the production of cytolytic free-radicals.
oxidopamine : A benzenetriol that is phenethylamine in which the hydrogens at positions 2, 4, and 5 on the phenyl ring are replaced by hydroxy groups. It occurs naturally in human urine, but is also produced as a metabolite of the drug DOPA (used for the treatment of Parkinson's disease).
Bipolar Disorder: A major affective disorder marked by severe mood swings (manic or major depressive episodes) and a tendency to remission and recurrence.
Excerpt | Relevance | Reference |
---|---|---|
" Chronic administration of lithium was found to prevent the development of hyperreactivity to mild footshock, while chronic electroconvulsive shock effected a return toward normal behavior." | 1.26 | A pharmacologically pertinent animal model of mania. ( Petty, F; Sherman, AD, 1981) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (50.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 1 (50.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Petty, F | 1 |
Sherman, AD | 1 |
Niculescu, AB | 1 |
Kelsoe, JR | 1 |
1 review available for oxidopamine and Bipolar Disorder
Article | Year |
---|---|
Convergent functional genomics: application to bipolar disorder.
Topics: Amphetamine; Animals; Bipolar Disorder; Cloning, Molecular; Gene Expression Profiling; Genetic Linka | 2001 |
1 other study available for oxidopamine and Bipolar Disorder
Article | Year |
---|---|
A pharmacologically pertinent animal model of mania.
Topics: Affective Disorders, Psychotic; Animals; Bipolar Disorder; Disease Models, Animal; Electroshock; Hum | 1981 |