Page last updated: 2024-11-02

oxidopamine and Bipolar Disorder

oxidopamine has been researched along with Bipolar Disorder in 2 studies

Oxidopamine: A neurotransmitter analogue that depletes noradrenergic stores in nerve endings and induces a reduction of dopamine levels in the brain. Its mechanism of action is related to the production of cytolytic free-radicals.
oxidopamine : A benzenetriol that is phenethylamine in which the hydrogens at positions 2, 4, and 5 on the phenyl ring are replaced by hydroxy groups. It occurs naturally in human urine, but is also produced as a metabolite of the drug DOPA (used for the treatment of Parkinson's disease).

Bipolar Disorder: A major affective disorder marked by severe mood swings (manic or major depressive episodes) and a tendency to remission and recurrence.

Research Excerpts

ExcerptRelevanceReference
" Chronic administration of lithium was found to prevent the development of hyperreactivity to mild footshock, while chronic electroconvulsive shock effected a return toward normal behavior."1.26A pharmacologically pertinent animal model of mania. ( Petty, F; Sherman, AD, 1981)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Petty, F1
Sherman, AD1
Niculescu, AB1
Kelsoe, JR1

Reviews

1 review available for oxidopamine and Bipolar Disorder

ArticleYear
Convergent functional genomics: application to bipolar disorder.
    Annals of medicine, 2001, Volume: 33, Issue:4

    Topics: Amphetamine; Animals; Bipolar Disorder; Cloning, Molecular; Gene Expression Profiling; Genetic Linka

2001

Other Studies

1 other study available for oxidopamine and Bipolar Disorder

ArticleYear
A pharmacologically pertinent animal model of mania.
    Journal of affective disorders, 1981, Volume: 3, Issue:4

    Topics: Affective Disorders, Psychotic; Animals; Bipolar Disorder; Disease Models, Animal; Electroshock; Hum

1981