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oxidopamine and Behavior Disorders

oxidopamine has been researched along with Behavior Disorders in 9 studies

Oxidopamine: A neurotransmitter analogue that depletes noradrenergic stores in nerve endings and induces a reduction of dopamine levels in the brain. Its mechanism of action is related to the production of cytolytic free-radicals.
oxidopamine : A benzenetriol that is phenethylamine in which the hydrogens at positions 2, 4, and 5 on the phenyl ring are replaced by hydroxy groups. It occurs naturally in human urine, but is also produced as a metabolite of the drug DOPA (used for the treatment of Parkinson's disease).

Research Excerpts

ExcerptRelevanceReference
"5% potassium oxonate (an uricase inhibitor) to induce hyperuricemia."3.91Feeding-produced subchronic high plasma levels of uric acid improve behavioral dysfunction in 6-hydroxydopamine-induced mouse model of Parkinson's disease. ( Dohgu, S; Fukae, J; Kataoka, Y; Koga, M; Matsumoto, J; Nakashima, A; Takata, F; Tsuboi, Y; Yamauchi, A, 2019)
"Severity of 6-OHDA-induced Parkinsonism was assessed by conventional behavioural tests."1.43Pretreatment with potassium channel blockers of 4-aminopyridine and tetraethylammonium attenuates behavioural symptoms of Parkinsonism induced by intrastriatal injection of 6-hydroxydopamine; the role of lipid peroxidation. ( Alipour Heidari, M; Dargahi, T; Faraji, A; Fraidouni, N; Haghdoost-Yazdi, H; Mahmudi, M; Piri, H, 2016)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (33.33)29.6817
2010's6 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nakashima, A1
Yamauchi, A1
Matsumoto, J1
Dohgu, S1
Takata, F1
Koga, M1
Fukae, J1
Tsuboi, Y1
Kataoka, Y1
Petri, D1
Pum, M1
Vesper, J1
Huston, JP1
Schnitzler, A1
Haghdoost-Yazdi, H1
Piri, H1
Faraji, A1
Fraidouni, N1
Dargahi, T1
Mahmudi, M1
Alipour Heidari, M1
Kim, TW1
Moon, Y1
Kim, K1
Lee, JE1
Koh, HC1
Rhyu, IJ1
Kim, H1
Sun, W1
Sheline, CT1
Zhu, J1
Zhang, W1
Shi, C1
Cai, AL1
Inden, M1
Kitamura, Y1
Takata, K1
Yasui, H1
Yoshimoto, K1
Ashihara, E1
Breese, GR1
Knapp, DJ1
Criswell, HE1
Moy, SS1
Papadeas, ST1
Blake, BL1
Cunningham, MG1
Connor, CM1
Zhang, K1
Benes, FM1
Pienaar, IS1
Schallert, T1
Russell, VA1
Kellaway, LA1
Carr, JA1
Daniels, WM1

Reviews

1 review available for oxidopamine and Behavior Disorders

ArticleYear
The neonate-6-hydroxydopamine-lesioned rat: a model for clinical neuroscience and neurobiological principles.
    Brain research. Brain research reviews, 2005, Volume: 48, Issue:1

    Topics: Age Factors; Animals; Animals, Newborn; Brain; Brain Chemistry; Disease Models, Animal; Dopamine; Ex

2005

Other Studies

8 other studies available for oxidopamine and Behavior Disorders

ArticleYear
Feeding-produced subchronic high plasma levels of uric acid improve behavioral dysfunction in 6-hydroxydopamine-induced mouse model of Parkinson's disease.
    Behavioural pharmacology, 2019, Volume: 30, Issue:1

    Topics: Adrenergic Agents; Animals; Apomorphine; Disease Models, Animal; Hyperuricemia; Male; Mental Disorde

2019
GABAA-receptor activation in the subthalamic nucleus compensates behavioral asymmetries in the hemiparkinsonian rat.
    Behavioural brain research, 2013, Sep-01, Volume: 252

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Agents; Amphetamine; Animals; Disease Models, Animal; Diz

2013
Pretreatment with potassium channel blockers of 4-aminopyridine and tetraethylammonium attenuates behavioural symptoms of Parkinsonism induced by intrastriatal injection of 6-hydroxydopamine; the role of lipid peroxidation.
    Neurological research, 2016, Volume: 38, Issue:4

    Topics: 4-Aminopyridine; Adrenergic Agents; Animals; Apomorphine; Corpus Striatum; Disease Models, Animal; D

2016
Dissociation of progressive dopaminergic neuronal death and behavioral impairments by Bax deletion in a mouse model of Parkinson's diseases.
    PloS one, 2011, Volume: 6, Issue:10

    Topics: Animals; Apoptosis; Apoptosis Inducing Factor; Atrophy; bcl-2-Associated X Protein; Disease Models,

2011
Mitochondrial inhibitor models of Huntington's disease and Parkinson's disease induce zinc accumulation and are attenuated by inhibition of zinc neurotoxicity in vitro or in vivo.
    Neuro-degenerative diseases, 2013, Volume: 11, Issue:1

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Carrier Proteins; Cation Transport Proteins;

2013
Detoxification of 6-hydroxydopamine-induced dopaminergic neurodegeneration by 5,5-dimethyl-1-pyrroline N-oxide, a radical trapper, in hemiparkinsonian rats.
    Biological & pharmaceutical bulletin, 2012, Volume: 35, Issue:9

    Topics: Animals; Antioxidants; Behavior, Animal; Cyclic N-Oxides; Disease Models, Animal; Dose-Response Rela

2012
Diminished serotonergic innervation of adult medial prefrontal cortex after 6-OHDA lesions in the newborn rat.
    Brain research. Developmental brain research, 2005, Jun-30, Volume: 157, Issue:2

    Topics: Animals; Animals, Newborn; Cell Communication; Cell Differentiation; Denervation; Disease Models, An

2005
Early pubertal female rats are more resistant than males to 6-hydroxydopamine neurotoxicity and behavioural deficits: a possible role for trophic factors.
    Restorative neurology and neuroscience, 2007, Volume: 25, Issue:5-6

    Topics: Analysis of Variance; Animals; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship,

2007