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oxidopamine and Basal Ganglia Diseases

oxidopamine has been researched along with Basal Ganglia Diseases in 7 studies

Oxidopamine: A neurotransmitter analogue that depletes noradrenergic stores in nerve endings and induces a reduction of dopamine levels in the brain. Its mechanism of action is related to the production of cytolytic free-radicals.
oxidopamine : A benzenetriol that is phenethylamine in which the hydrogens at positions 2, 4, and 5 on the phenyl ring are replaced by hydroxy groups. It occurs naturally in human urine, but is also produced as a metabolite of the drug DOPA (used for the treatment of Parkinson's disease).

Basal Ganglia Diseases: Diseases of the BASAL GANGLIA including the PUTAMEN; GLOBUS PALLIDUS; claustrum; AMYGDALA; and CAUDATE NUCLEUS. DYSKINESIAS (most notably involuntary movements and alterations of the rate of movement) represent the primary clinical manifestations of these disorders. Common etiologies include CEREBROVASCULAR DISORDERS; NEURODEGENERATIVE DISEASES; and CRANIOCEREBRAL TRAUMA.

Research Excerpts

ExcerptRelevanceReference
"The frequency of the induction of parkinsonism-like signs was minimal in the first 2 weeks and reached a maximum point 4 weeks after the 6-OHDA injection."1.32"Hydrocephalus-parkinsonism complex": progressive hydrocephalus as a factor affecting extrapyramidal tract disorder-an experimental study. ( Hidaka, M; Kim, DS; Oi, S, 2004)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19903 (42.86)18.7374
1990's2 (28.57)18.2507
2000's2 (28.57)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Oi, S1
Kim, DS1
Hidaka, M1
Muñoz, AM1
Rey, P1
Parga, J1
Guerra, MJ1
Labandeira-Garcia, JL1
Shimoyama, M1
Kito, S1
Itoga, E1
Kishida, T1
Nanba, K1
Bourson, A1
Boess, FG1
Bös, M1
Sleight, AJ1
Carlson, JD1
Pearlstein, RD1
Buchholz, J1
Iacono, RP1
Maeda, G1
Strömberg, I1
Johnson, S1
Hoffer, B1
Olson, L1
Brundin, P1
Isacson, O1
Gage, FH1
Prochiantz, A1
Björklund, A1

Other Studies

7 other studies available for oxidopamine and Basal Ganglia Diseases

ArticleYear
"Hydrocephalus-parkinsonism complex": progressive hydrocephalus as a factor affecting extrapyramidal tract disorder-an experimental study.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2004, Volume: 20, Issue:1

    Topics: Animals; Antiparkinson Agents; Apomorphine; Basal Ganglia Diseases; Behavior, Animal; Disease Models

2004
Glial overexpression of heme oxygenase-1: a histochemical marker for early stages of striatal damage.
    Journal of chemical neuroanatomy, 2005, Volume: 29, Issue:2

    Topics: 5,7-Dihydroxytryptamine; Afferent Pathways; Animals; Astrocytes; Basal Ganglia Diseases; Biomarkers;

2005
Binding experiments of muscarinic acetylcholine and dopamine receptors in human brains with emphasis on a case of striatonigral degeneration.
    Japanese journal of pharmacology, 1982, Volume: 32, Issue:6

    Topics: Animals; Basal Ganglia Diseases; Brain; Caudate Nucleus; Corpus Striatum; Humans; Hydroxydopamines;

1982
Involvement of 5-HT6 receptors in nigro-striatal function in rodents.
    British journal of pharmacology, 1998, Volume: 125, Issue:7

    Topics: Adrenergic Agents; Animals; Basal Ganglia Diseases; Benzazepines; Catalepsy; Clozapine; Corpus Stria

1998
Regional metabolic changes in the pedunculopontine nucleus of unilateral 6-hydroxydopamine Parkinson's model rats.
    Brain research, 1999, May-15, Volume: 828, Issue:1-2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antimetabolites; Basal Ganglia Diseases; Cerebral Cortex; D

1999
Reinnervation of dopamine-denervated striatum by substantia nigra transplants: immunohistochemical and electrophysiological correlates.
    Neuroscience, 1985, Volume: 14, Issue:4

    Topics: Animals; Basal Ganglia Diseases; Corpus Striatum; Electrophysiology; Female; Hydroxydopamines; Oxido

1985
The rotating 6-hydroxydopamine-lesioned mouse as a model for assessing functional effects of neuronal grafting.
    Brain research, 1986, Feb-26, Volume: 366, Issue:1-2

    Topics: Amphetamine; Animals; Basal Ganglia Diseases; Corpus Striatum; Disease Models, Animal; Dopamine; Hyd

1986