oxidopamine has been researched along with Attention Deficit Disorder with Hyperactivity in 27 studies
Oxidopamine: A neurotransmitter analogue that depletes noradrenergic stores in nerve endings and induces a reduction of dopamine levels in the brain. Its mechanism of action is related to the production of cytolytic free-radicals.
oxidopamine : A benzenetriol that is phenethylamine in which the hydrogens at positions 2, 4, and 5 on the phenyl ring are replaced by hydroxy groups. It occurs naturally in human urine, but is also produced as a metabolite of the drug DOPA (used for the treatment of Parkinson's disease).
Attention Deficit Disorder with Hyperactivity: A behavior disorder originating in childhood in which the essential features are signs of developmentally inappropriate inattention, impulsivity, and hyperactivity. Although most individuals have symptoms of both inattention and hyperactivity-impulsivity, one or the other pattern may be predominant. The disorder is more frequent in males than females. Onset is in childhood. Symptoms often attenuate during late adolescence although a minority experience the full complement of symptoms into mid-adulthood. (From DSM-V)
| Excerpt | Relevance | Reference |
|---|---|---|
| " Moreover, in this case a classical pharmacokinetic-pharmacodynamic relationship based on free brain concentrations seems to be less appropriate than target engagement pharmacodynamic readouts." | 1.42 | Effects of sarizotan in animal models of ADHD: challenging pharmacokinetic-pharmacodynamic relationships. ( Bizot, JC; Brown, RW; Danysz, W; Dimpfel, W; Flik, G; Greco, S; Jatzke, CC; Jenssen, AK; Kostrzewa, R; McCreary, A; Parsons, CG; Tober, C, 2015) |
| "Nowadays the pharmacological treatment of the attention deficit hyperactivity disorder (ADHD) is based on amphetamine derivatives (i." | 1.37 | Caffeine improves attention deficit in neonatal 6-OHDA lesioned rats, an animal model of attention deficit hyperactivity disorder (ADHD). ( Ahern, S; Caballero, M; Carbonell, L; Ciruela, F; Cuffí, ML; Fernández-Dueñas, V; Núñez, F; Sánchez, S, 2011) |
| "Atomoxetine greatly reduced motor hyperactivity in 6-OHDA-lesioned rats while exhibiting transient sedative effects in sham controls." | 1.33 | Atomoxetine blocks motor hyperactivity in neonatal 6-hydroxydopamine-lesioned rats: implications for treatment of attention-deficit hyperactivity disorder. ( Baldessarini, RJ; Moran-Gates, T; Tarazi, FI; Zhang, K, 2005) |
| "A model of minimal brain dysfunction (MBD) in rats based on injection of 6-OH-dopamine (DA) intracisternally on the 5th day of life has been described previously." | 1.26 | Dopamine receptors in a rat model of minimal brain dysfunction. ( Belmaker, RH; Brecher-Fride, E; Ebstein, RP; Eisenberg, J; Weizman, R, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (7.41) | 18.7374 |
| 1990's | 2 (7.41) | 18.2507 |
| 2000's | 11 (40.74) | 29.6817 |
| 2010's | 9 (33.33) | 24.3611 |
| 2020's | 3 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Stanford, SC | 1 |
| Bouchatta, O | 2 |
| Aby, F | 1 |
| Sifeddine, W | 2 |
| Bouali-Benazzouz, R | 2 |
| Brochoire, L | 1 |
| Manouze, H | 2 |
| Fossat, P | 2 |
| Ba M'Hamed, S | 1 |
| Bennis, M | 3 |
| Landry, M | 3 |
| Ba-M'hamed, S | 2 |
| Suzuki, M | 1 |
| Nakayama, M | 1 |
| Ando, KB | 1 |
| Arima, S | 1 |
| Nakamura, Y | 1 |
| Yokota, M | 1 |
| Murakami, S | 1 |
| Kerekes, N | 1 |
| Freund, N | 2 |
| MacGillivilray, HT | 1 |
| Thompson, BS | 2 |
| Lukkes, JL | 2 |
| Stanis, JJ | 1 |
| Brenhouse, HC | 1 |
| Andersen, SL | 2 |
| Banerjee, E | 1 |
| Nandagopal, K | 1 |
| Danysz, W | 1 |
| Flik, G | 1 |
| McCreary, A | 1 |
| Tober, C | 1 |
| Dimpfel, W | 1 |
| Bizot, JC | 1 |
| Kostrzewa, R | 1 |
| Brown, RW | 1 |
| Jatzke, CC | 1 |
| Greco, S | 1 |
| Jenssen, AK | 1 |
| Parsons, CG | 1 |
| Meda, S | 1 |
| Pålsson, E | 1 |
| Söderlund, G | 1 |
| Klamer, D | 1 |
| Bergquist, F | 1 |
| Caballero, M | 1 |
| Núñez, F | 1 |
| Ahern, S | 1 |
| Cuffí, ML | 1 |
| Carbonell, L | 1 |
| Sánchez, S | 1 |
| Fernández-Dueñas, V | 1 |
| Ciruela, F | 1 |
| Masuo, Y | 3 |
| Shibato, J | 1 |
| Rakwal, R | 1 |
| Zhang, K | 4 |
| Davids, E | 3 |
| Tarazi, FI | 4 |
| Baldessarini, RJ | 4 |
| Ohno, M | 1 |
| Avale, ME | 1 |
| Falzone, TL | 1 |
| Gelman, DM | 1 |
| Low, MJ | 1 |
| Grandy, DK | 1 |
| Rubinstein, M | 1 |
| Ikegami, M | 1 |
| Iwasaki, T | 2 |
| Ishido, M | 2 |
| Morita, M | 2 |
| Oka, S | 2 |
| Moran-Gates, T | 1 |
| van der Kooij, MA | 1 |
| Glennon, JC | 1 |
| Nowak, P | 1 |
| Bortel, A | 1 |
| Dabrowska, J | 1 |
| Oswiecimska, J | 1 |
| Drosik, M | 1 |
| Kwiecinski, A | 1 |
| Opara, J | 1 |
| Kostrzewa, RM | 2 |
| Brus, R | 2 |
| Eisenberg, J | 1 |
| Brecher-Fride, E | 1 |
| Weizman, R | 1 |
| Ebstein, RP | 1 |
| Belmaker, RH | 1 |
| Kalbfleisch, JH | 1 |
| Perry, KW | 1 |
| Fuller, RW | 1 |
| Fahlke, C | 1 |
| Hansen, S | 1 |
| Takasuna, M | 1 |
4 reviews available for oxidopamine and Attention Deficit Disorder with Hyperactivity
| Article | Year |
|---|---|
Does serotonin deficit mediate susceptibility to ADHD?
Topics: Adolescent; Animals; Animals, Newborn; Attention Deficit Disorder with Hyperactivity; Central Nervou | 2015 |
Animal models of attention-deficit hyperactivity disorder.
Topics: Animals; Attention Deficit Disorder with Hyperactivity; Disease Models, Animal; Dopamine; Genetic Va | 2003 |
The dopaminergic system in attention deficit/hyperactivity disorder.
Topics: Animals; Attention Deficit Disorder with Hyperactivity; Brain; Disease Models, Animal; Dopamine; Dop | 2003 |
Animal models concerning the role of dopamine in attention-deficit hyperactivity disorder.
Topics: Animals; Attention Deficit Disorder with Hyperactivity; Brain; Disease Models, Animal; Dopamine; Dop | 2007 |
23 other studies available for oxidopamine and Attention Deficit Disorder with Hyperactivity
| Article | Year |
|---|---|
Animal Models of ADHD?
Topics: Animals; Attention Deficit Disorder with Hyperactivity; Behavior, Animal; Disease Models, Animal; Im | 2022 |
Pain hypersensitivity in a pharmacological mouse model of attention-deficit/hyperactivity disorder.
Topics: Animals; Attention Deficit Disorder with Hyperactivity; Disease Models, Animal; Gyrus Cinguli; Hyper | 2022 |
Effect of atomoxetine on ADHD-pain hypersensitization comorbidity in 6-OHDA lesioned mice.
Topics: Adrenergic Uptake Inhibitors; Animals; Atomoxetine Hydrochloride; Attention Deficit Disorder with Hy | 2023 |
Sleep Disturbance and Hyperactivity Detected by Actigraphy in Rats with Allergic Rhinitis or Attention-Deficit Hyperactivity Disorder.
Topics: Actigraphy; Animals; Attention Deficit Disorder with Hyperactivity; Behavior, Animal; Eosinophilia; | 2018 |
Neonatal 6-OHDA lesion model in mouse induces Attention-Deficit/ Hyperactivity Disorder (ADHD)-like behaviour.
Topics: Animals; Animals, Newborn; Attention Deficit Disorder with Hyperactivity; Behavior, Animal; Disease | 2018 |
Sex-dependent changes in ADHD-like behaviors in juvenile rats following cortical dopamine depletion.
Topics: Adrenergic Agents; Animals; Attention Deficit Disorder with Hyperactivity; Cocaine; Cues; Dopamine; | 2014 |
Effects of sarizotan in animal models of ADHD: challenging pharmacokinetic-pharmacodynamic relationships.
Topics: Action Potentials; Animals; Attention Deficit Disorder with Hyperactivity; Brain; Cross-Over Studies | 2015 |
Preventative treatment in an animal model of ADHD: Behavioral and biochemical effects of methylphenidate and its interactions with ovarian hormones in female rats.
Topics: Animals; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Cocaine; | 2016 |
Noise benefit in prepulse inhibition of the acoustic startle reflex.
Topics: Acoustic Stimulation; Analysis of Variance; Animals; Attention Deficit Disorder with Hyperactivity; | 2011 |
Caffeine improves attention deficit in neonatal 6-OHDA lesioned rats, an animal model of attention deficit hyperactivity disorder (ADHD).
Topics: Animals; Attention; Attention Deficit Disorder with Hyperactivity; Caffeine; Central Nervous System | 2011 |
ADHD animal model characterization: transcriptomics and proteomics analyses.
Topics: Animals; Animals, Newborn; Attention Deficit Disorder with Hyperactivity; Behavior, Animal; Brain; D | 2012 |
Serotonin transporter binding increases in caudate-putamen and nucleus accumbens after neonatal 6-hydroxydopamine lesions in rats: implications for motor hyperactivity.
Topics: Aging; Animals; Animals, Newborn; Attention Deficit Disorder with Hyperactivity; Carrier Proteins; D | 2002 |
The dopamine D4 receptor is essential for hyperactivity and impaired behavioral inhibition in a mouse model of attention deficit/hyperactivity disorder.
Topics: Amphetamine; Animals; Animals, Outbred Strains; Attention Deficit Disorder with Hyperactivity; Behav | 2004 |
[Effects of neurotensin microinjected into ventral tegmental area on spontaneous motor activity in neonatal 6-hydroxydopamine-treated rats].
Topics: Animals; Animals, Newborn; Attention Deficit Disorder with Hyperactivity; Disease Models, Animal; Do | 2004 |
Effects of neonatal treatment with 6-hydroxydopamine and endocrine disruptors on motor activity and gene expression in rats.
Topics: Animals; Animals, Newborn; Attention Deficit Disorder with Hyperactivity; Benzhydryl Compounds; Brai | 2004 |
Motor hyperactivity caused by a deficit in dopaminergic neurons and the effects of endocrine disruptors: a study inspired by the physiological roles of PACAP in the brain.
Topics: Animals; Animals, Newborn; Attention Deficit Disorder with Hyperactivity; Autistic Disorder; Benzhyd | 2004 |
Atomoxetine blocks motor hyperactivity in neonatal 6-hydroxydopamine-lesioned rats: implications for treatment of attention-deficit hyperactivity disorder.
Topics: Adrenergic Agents; Adrenergic Uptake Inhibitors; Analysis of Variance; Animals; Animals, Newborn; At | 2005 |
Amphetamine and mCPP effects on dopamine and serotonin striatal in vivo microdialysates in an animal model of hyperactivity.
Topics: 3,4-Dihydroxyphenylacetic Acid; 5,6-Dihydroxytryptamine; Age Factors; Amphetamine; Animals; Attentio | 2007 |
Dopamine receptors in a rat model of minimal brain dysfunction.
Topics: Aging; Animals; Animals, Newborn; Attention Deficit Disorder with Hyperactivity; Caudate Nucleus; Di | 1982 |
Proposed animal model of attention deficit hyperactivity disorder.
Topics: 5,7-Dihydroxytryptamine; Animals; Animals, Newborn; Attention Deficit Disorder with Hyperactivity; C | 1994 |
Alcohol responsiveness, hyperreactivity, and motor restlessness in an animal model for attention-deficit hyperactivity disorder.
Topics: Alcohol Drinking; Animals; Attention Deficit Disorder with Hyperactivity; Brain Chemistry; Diazepam; | 1999 |
Effects of dopamine D4 receptor-selective antagonists on motor hyperactivity in rats with neonatal 6-hydroxydopamine lesions.
Topics: Animals; Animals, Newborn; Attention Deficit Disorder with Hyperactivity; Dopamine Antagonists; Dopa | 2002 |
[Spontaneous motor activity and radial-maze learning in rats neonatally treated with 6-hydroxydopamine].
Topics: Animals; Animals, Newborn; Attention Deficit Disorder with Hyperactivity; Desipramine; Female; Hydro | 1986 |