Page last updated: 2024-11-02

oxidopamine and Atrophy

oxidopamine has been researched along with Atrophy in 8 studies

Oxidopamine: A neurotransmitter analogue that depletes noradrenergic stores in nerve endings and induces a reduction of dopamine levels in the brain. Its mechanism of action is related to the production of cytolytic free-radicals.
oxidopamine : A benzenetriol that is phenethylamine in which the hydrogens at positions 2, 4, and 5 on the phenyl ring are replaced by hydroxy groups. It occurs naturally in human urine, but is also produced as a metabolite of the drug DOPA (used for the treatment of Parkinson's disease).

Atrophy: Decrease in the size of a cell, tissue, organ, or multiple organs, associated with a variety of pathological conditions such as abnormal cellular changes, ischemia, malnutrition, or hormonal changes.

Research Excerpts

ExcerptRelevanceReference
"The influence of embryonic mesencephalic, striatal and mesencephalic/striatal co-grafts on amphetamine- and apomorphine-induced rotation behaviour was assessed in a rat model of multiple system atrophy/striatonigral degeneration type using dopamine D1 ([3H]SCH23390) and D2 ([3H]spiperone) receptor and dopamine re-uptake ([3H]mazindol) autoradiography."7.70Autoradiographic study of striatal dopamine re-uptake sites and dopamine D1 and D2 receptors in a 6-hydroxydopamine and quinolinic acid double-lesion rat model of striatonigral degeneration (multiple system atrophy) and effects of embryonic ventral mesenc ( Granata, R; Jenner, P; Laboyrie, P; Poewe, W; Puschban, Z; Quinn, NP; Scherfler, C; Wenning, GK, 2000)
"The influence of embryonic mesencephalic, striatal and mesencephalic/striatal co-grafts on amphetamine- and apomorphine-induced rotation behaviour was assessed in a rat model of multiple system atrophy/striatonigral degeneration type using dopamine D1 ([3H]SCH23390) and D2 ([3H]spiperone) receptor and dopamine re-uptake ([3H]mazindol) autoradiography."3.70Autoradiographic study of striatal dopamine re-uptake sites and dopamine D1 and D2 receptors in a 6-hydroxydopamine and quinolinic acid double-lesion rat model of striatonigral degeneration (multiple system atrophy) and effects of embryonic ventral mesenc ( Granata, R; Jenner, P; Laboyrie, P; Poewe, W; Puschban, Z; Quinn, NP; Scherfler, C; Wenning, GK, 2000)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (37.50)18.2507
2000's3 (37.50)29.6817
2010's2 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Westphal, R1
Sumiyoshi, A1
Simmons, C1
Mesquita, M1
Wood, TC1
Williams, SC1
Vernon, AC1
Cash, D1
Kim, TW1
Moon, Y1
Kim, K1
Lee, JE1
Koh, HC1
Rhyu, IJ1
Kim, H1
Sun, W1
Sherren, N1
Pappas, BA1
Karagüzel, G1
Gedikoğlu, G1
Tanyel, FC1
Büyükpamukçu, N1
Hiçsönmez, A1
Rosenblad, C1
Kirik, D1
Devaux, B1
Moffat, B1
Phillips, HS1
Björklund, A1
Puschban, Z1
Scherfler, C1
Granata, R1
Laboyrie, P1
Quinn, NP1
Jenner, P1
Poewe, W1
Wenning, GK1
Roghani, M1
Behzadi, G1
Finch, CE1
Kohama, SG1
Pasinetti, GM1

Reviews

1 review available for oxidopamine and Atrophy

ArticleYear
Ovarian steroid and neurotoxin models of brain aging in rodents.
    Annals of the New York Academy of Sciences, 1992, May-11, Volume: 648

    Topics: Aging; Animals; Atrophy; Brain; Estrogens; Female; Mice; Mice, Inbred C57BL; Neurons; Neurotoxins; O

1992

Other Studies

7 other studies available for oxidopamine and Atrophy

ArticleYear
Characterization of gray matter atrophy following 6-hydroxydopamine lesion of the nigrostriatal system.
    Neuroscience, 2016, Oct-15, Volume: 334

    Topics: Animals; Apomorphine; Atrophy; Brain; Dopamine Agonists; Dopaminergic Neurons; Functional Laterality

2016
Dissociation of progressive dopaminergic neuronal death and behavioral impairments by Bax deletion in a mouse model of Parkinson's diseases.
    PloS one, 2011, Volume: 6, Issue:10

    Topics: Animals; Apoptosis; Apoptosis Inducing Factor; Atrophy; bcl-2-Associated X Protein; Disease Models,

2011
Selective acetylcholine and dopamine lesions in neonatal rats produce distinct patterns of cortical dendritic atrophy in adulthood.
    Neuroscience, 2005, Volume: 136, Issue:2

    Topics: Acetylcholine; Animals; Animals, Newborn; Antibodies, Monoclonal; Atrophy; Body Weight; Brain Chemis

2005
Subsequent biological effects of chemical sympathectomy in rats undergoing unilateral testicular torsion.
    European urology, 1995, Volume: 28, Issue:2

    Topics: Animals; Atrophy; Female; Fertility; Male; Necrosis; Oxidopamine; Pregnancy; Random Allocation; Rats

1995
Protection and regeneration of nigral dopaminergic neurons by neurturin or GDNF in a partial lesion model of Parkinson's disease after administration into the striatum or the lateral ventricle.
    The European journal of neuroscience, 1999, Volume: 11, Issue:5

    Topics: Amphetamine; Animals; Antibodies; Apomorphine; Atrophy; Body Weight; Cerebral Ventricles; Corpus Str

1999
Autoradiographic study of striatal dopamine re-uptake sites and dopamine D1 and D2 receptors in a 6-hydroxydopamine and quinolinic acid double-lesion rat model of striatonigral degeneration (multiple system atrophy) and effects of embryonic ventral mesenc
    Neuroscience, 2000, Volume: 95, Issue:2

    Topics: Amphetamine; Animals; Apomorphine; Atrophy; Autoradiography; Behavior, Animal; Brain Tissue Transpla

2000
Neuroprotective effect of vitamin E on the early model of Parkinson's disease in rat: behavioral and histochemical evidence.
    Brain research, 2001, Feb-16, Volume: 892, Issue:1

    Topics: Amphetamine; Animals; Apomorphine; Atrophy; Axonal Transport; Corpus Striatum; Disease Models, Anima

2001