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oxidopamine and Astrocytoma

oxidopamine has been researched along with Astrocytoma in 3 studies

Oxidopamine: A neurotransmitter analogue that depletes noradrenergic stores in nerve endings and induces a reduction of dopamine levels in the brain. Its mechanism of action is related to the production of cytolytic free-radicals.
oxidopamine : A benzenetriol that is phenethylamine in which the hydrogens at positions 2, 4, and 5 on the phenyl ring are replaced by hydroxy groups. It occurs naturally in human urine, but is also produced as a metabolite of the drug DOPA (used for the treatment of Parkinson's disease).

Astrocytoma: Neoplasms of the brain and spinal cord derived from glial cells which vary from histologically benign forms to highly anaplastic and malignant tumors. Fibrillary astrocytomas are the most common type and may be classified in order of increasing malignancy (grades I through IV). In the first two decades of life, astrocytomas tend to originate in the cerebellar hemispheres; in adults, they most frequently arise in the cerebrum and frequently undergo malignant transformation. (From Devita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2013-7; Holland et al., Cancer Medicine, 3d ed, p1082)

Research Excerpts

ExcerptRelevanceReference
"As a model of reactive gliosis secondary to degenerative disorders, 6-hydroxydopamine (6-OHDA) lesion of the substantia nigra in the rat was performed."1.27Identification of a human glial fibrillary acidic protein cDNA: a tool for the molecular analysis of reactive gliosis in the mammalian central nervous system. ( Boularand, S; De Vitry, F; Faucon Biguet, N; Mallet, J; Privat, A; Rataboul, P; Vernier, P, 1988)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (33.33)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Eskandarian Boroujeni, M1
Aliaghaei, A1
Maghsoudi, N2
Gardaneh, M2
Safi, R1
Panahi, Y1
Zaefizadeh, M1
Gharib, E1
Rataboul, P1
Faucon Biguet, N1
Vernier, P1
De Vitry, F1
Boularand, S1
Privat, A1
Mallet, J1

Other Studies

3 other studies available for oxidopamine and Astrocytoma

ArticleYear
Complementation of dopaminergic signaling by Pitx3-GDNF synergy induces dopamine secretion by multipotent Ntera2 cells.
    Journal of cellular biochemistry, 2020, Volume: 121, Issue:1

    Topics: Animals; Astrocytoma; Behavior, Animal; Cell Differentiation; Cell Line, Tumor; Culture Media, Condi

2020
Optimized quantities of GDNF overexpressed by engineered astrocytes are critical for protection of neuroblastoma cells against 6-OHDA toxicity.
    Journal of molecular neuroscience : MN, 2012, Volume: 46, Issue:3

    Topics: Animals; Apoptosis; Astrocytes; Astrocytoma; Cell Death; Cell Line, Tumor; Cytoprotection; Feasibili

2012
Identification of a human glial fibrillary acidic protein cDNA: a tool for the molecular analysis of reactive gliosis in the mammalian central nervous system.
    Journal of neuroscience research, 1988, Volume: 20, Issue:2

    Topics: Amino Acid Sequence; Animals; Astrocytoma; Base Sequence; DNA; Glial Fibrillary Acidic Protein; Glio

1988