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oxidopamine and Arrhythmias, Cardiac

oxidopamine has been researched along with Arrhythmias, Cardiac in 10 studies

Oxidopamine: A neurotransmitter analogue that depletes noradrenergic stores in nerve endings and induces a reduction of dopamine levels in the brain. Its mechanism of action is related to the production of cytolytic free-radicals.
oxidopamine : A benzenetriol that is phenethylamine in which the hydrogens at positions 2, 4, and 5 on the phenyl ring are replaced by hydroxy groups. It occurs naturally in human urine, but is also produced as a metabolite of the drug DOPA (used for the treatment of Parkinson's disease).

Arrhythmias, Cardiac: Any disturbances of the normal rhythmic beating of the heart or MYOCARDIAL CONTRACTION. Cardiac arrhythmias can be classified by the abnormalities in HEART RATE, disorders of electrical impulse generation, or impulse conduction.

Research Excerpts

ExcerptRelevanceReference
"No protection against drug-induced arrhythmia or death was afforded by this procedure."5.27Does chlorpromazine produce cardiac arrhythmia via the central nervous system? ( Lathers, CM; Lipka, LJ; Roberts, J, 1988)
"1 micrograms kg-1 min-1) or chronic (50-60 mg kg-1 daily for 12 days) propranolol treatment had little effect on arrhythmias, or other responses to ligation."3.66The effect of modification of sympathetic activity on responses to ligation of a coronary artery in the conscious rat. ( Botting, JH; Johnston, KM; Macleod, BA; Walker, MJ, 1983)
"This study determined whether the protective effect of reserpine against ouabain-induced ventricular arrhythmias in the cat is due to an action of the drug on the adrenergic nerve terminal."3.66The action of reserpine, 6-hydroxydopamine, and bretylium on digitalis-induced cardiotoxicity. ( Baskin, SI; Gerard-Ciminera, JL; Kelliher, GJ; Krusz, JC; Lathers, CM; Roberts, J, 1981)
"Yohimbine was antiarrhythmic in the presence and absence of platelets, suggesting direct myocardial effects, but BN 52021 had no antiarrhythmic effects."1.29Myocardial ischaemia induces platelet activation with adverse electrophysiological and arrhythmogenic effects. ( Flores, NA; Goulielmos, NV; Seghatchian, MJ; Sheridan, DJ, 1994)
"Arrhythmias were significantly more frequent during low flow (10% of control) than zero flow ischaemia and were most frequent during reperfusion following 30 minute ischaemia."1.27The deleterious effects of myocardial catecholamines on cellular electrophysiology and arrhythmias during ischaemia and reperfusion. ( Penny, WJ, 1984)
"No protection against drug-induced arrhythmia or death was afforded by this procedure."1.27Does chlorpromazine produce cardiac arrhythmia via the central nervous system? ( Lathers, CM; Lipka, LJ; Roberts, J, 1988)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19907 (70.00)18.7374
1990's1 (10.00)18.2507
2000's1 (10.00)29.6817
2010's0 (0.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Menezes-Rodrigues, FS1
de Oliveira, MP1
Araújo, EA1
Ferraz, HB1
Finsterer, J1
Olszewer, E1
Taha, MO1
Scorza, CA1
Caricati-Neto, A1
Scorza, FA1
Wakita, Y1
Botting, JH1
Johnston, KM1
Macleod, BA1
Walker, MJ1
Culling, W2
Penny, WJ3
Lewis, MJ2
Middleton, K1
Sheridan, DJ3
Shavit, S1
Gassner, S1
Korczyn, AD1
Lathers, CM2
Gerard-Ciminera, JL1
Baskin, SI1
Krusz, JC1
Kelliher, GJ1
Roberts, J2
Flores, NA1
Goulielmos, NV1
Seghatchian, MJ1
Lipka, LJ1

Other Studies

10 other studies available for oxidopamine and Arrhythmias, Cardiac

ArticleYear
Role of cardiac β
    Clinics (Sao Paulo, Brazil), 2023, Volume: 78

    Topics: Adrenergic Agents; Animals; Arrhythmias, Cardiac; Oxidopamine; Parkinson Disease; Rats; Receptors, P

2023
Inotropic, chronotropic, and arrhythmogenic effects of dopamine on the isolated working heart of rabbit.
    The journal of physiological sciences : JPS, 2007, Volume: 57, Issue:3

    Topics: Animals; Arrhythmias, Cardiac; Blood Pressure; Cardiotonic Agents; Dopamine; Dose-Response Relations

2007
The effect of modification of sympathetic activity on responses to ligation of a coronary artery in the conscious rat.
    British journal of pharmacology, 1983, Volume: 79, Issue:1

    Topics: Adrenalectomy; Adrenergic beta-Antagonists; Animals; Arrhythmias, Cardiac; Blood Pressure; Coronary

1983
Effects of myocardial catecholamine depletion on cellular electrophysiology and arrhythmias during ischaemia and reperfusion.
    Cardiovascular research, 1984, Volume: 18, Issue:11

    Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Catecholamines; Coronary Disease; Glycogen; Guinea

1984
Cardiac denervation supersensitivity produced in guinea pigs by 6-hydroxy-dopamine.
    Pharmacological research communications, 1984, Volume: 16, Issue:2

    Topics: Animals; Arrhythmias, Cardiac; Catecholamines; Dose-Response Relationship, Drug; Epinephrine; Guinea

1984
The deleterious effects of myocardial catecholamines on cellular electrophysiology and arrhythmias during ischaemia and reperfusion.
    European heart journal, 1984, Volume: 5, Issue:12

    Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Catecholamines; Coronary Disease; Electrophysiolog

1984
The action of reserpine, 6-hydroxydopamine, and bretylium on digitalis-induced cardiotoxicity.
    European journal of pharmacology, 1981, Dec-17, Volume: 76, Issue:4

    Topics: Animals; Arrhythmias, Cardiac; Blood Pressure; Bretylium Compounds; Bretylium Tosylate; Cats; Digita

1981
Myocardial ischaemia induces platelet activation with adverse electrophysiological and arrhythmogenic effects.
    Cardiovascular research, 1994, Volume: 28, Issue:11

    Topics: Animals; Arrhythmias, Cardiac; Aspirin; Biphenyl Compounds; Blood Platelets; Colforsin; Diterpenes;

1994
Antiarrhythmic and electrophysiological effects of alpha adrenoceptor blockade during myocardial ischaemia and reperfusion in isolated guinea-pig heart.
    Journal of molecular and cellular cardiology, 1985, Volume: 17, Issue:4

    Topics: Adrenergic alpha-Antagonists; Animals; Arrhythmias, Cardiac; Catecholamines; Coronary Disease; Elect

1985
Does chlorpromazine produce cardiac arrhythmia via the central nervous system?
    Journal of clinical pharmacology, 1988, Volume: 28, Issue:11

    Topics: Animals; Arrhythmias, Cardiac; Blood Pressure; Cats; Central Nervous System; Chlorpromazine; Decereb

1988