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oxidopamine and Anhedonia

oxidopamine has been researched along with Anhedonia in 5 studies

Oxidopamine: A neurotransmitter analogue that depletes noradrenergic stores in nerve endings and induces a reduction of dopamine levels in the brain. Its mechanism of action is related to the production of cytolytic free-radicals.
oxidopamine : A benzenetriol that is phenethylamine in which the hydrogens at positions 2, 4, and 5 on the phenyl ring are replaced by hydroxy groups. It occurs naturally in human urine, but is also produced as a metabolite of the drug DOPA (used for the treatment of Parkinson's disease).

Anhedonia: Inability to experience pleasure due to impairment or dysfunction of normal psychological and neurobiological mechanisms. It is a symptom of many PSYCHOTIC DISORDERS (e.g., DEPRESSIVE DISORDER, MAJOR; and SCHIZOPHRENIA).

Research Excerpts

ExcerptRelevanceReference
"Parkinson's disease is a chronic neurodegenerative disorder characterized by cardinal motor features, such as bradykinesia, but also vocal deficits (e."5.48Effects of ketamine on vocal impairment, gait changes, and anhedonia induced by bilateral 6-OHDA infusion into the substantia nigra pars compacta in rats: Therapeutic implications for Parkinson's disease. ( Andreatini, R; Bruginski, E; Campos, FR; de Almeida Soares Hocayen, P; Kanazawa, LKS; Miyoshi, E; Schwarting, RKW; Stern, CAJ; Vecchia, DD; Vital, MABF; Wendler, E; Wöhr, M, 2018)
"Parkinson's disease is a neurodegenerative disorder partly caused by the loss of the dopamine neurons of the nigrostriatal pathway."1.56Ablation of the tail of the ventral tegmental area compensates symptoms in an experimental model of Parkinson's disease. ( Barrot, M; Bezard, E; Bido, S; Dovero, S; Faivre, F; Joshi, A; Sánchez-Catalán, MJ, 2020)
"Parkinson's disease is a chronic neurodegenerative disorder characterized by cardinal motor features, such as bradykinesia, but also vocal deficits (e."1.48Effects of ketamine on vocal impairment, gait changes, and anhedonia induced by bilateral 6-OHDA infusion into the substantia nigra pars compacta in rats: Therapeutic implications for Parkinson's disease. ( Andreatini, R; Bruginski, E; Campos, FR; de Almeida Soares Hocayen, P; Kanazawa, LKS; Miyoshi, E; Schwarting, RKW; Stern, CAJ; Vecchia, DD; Vital, MABF; Wendler, E; Wöhr, M, 2018)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (80.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Faivre, F1
Sánchez-Catalán, MJ1
Dovero, S1
Bido, S1
Joshi, A1
Bezard, E1
Barrot, M1
Vecchia, DD1
Kanazawa, LKS1
Wendler, E1
de Almeida Soares Hocayen, P1
Bruginski, E1
Campos, FR1
Stern, CAJ1
Vital, MABF1
Miyoshi, E1
Wöhr, M1
Schwarting, RKW1
Andreatini, R2
Marques, NF1
Binder, LB1
Roversi, K1
Sampaio, TB1
Constantino, LC1
Prediger, RD2
Tasca, CI1
Santiago, RM1
Tonin, FS1
Barbiero, J1
Zaminelli, T1
Boschen, SL1
Da Cunha, C1
Lima, MM1
Vital, MA1
Matheus, FC1
Rial, D1
Real, JI1
Lemos, C1
Takahashi, RN1
Bertoglio, LJ1
Cunha, RA1

Other Studies

5 other studies available for oxidopamine and Anhedonia

ArticleYear
Ablation of the tail of the ventral tegmental area compensates symptoms in an experimental model of Parkinson's disease.
    Neurobiology of disease, 2020, Volume: 139

    Topics: Anhedonia; Animals; Dopamine; Dopaminergic Neurons; Male; Models, Theoretical; Neural Pathways; Oxid

2020
Effects of ketamine on vocal impairment, gait changes, and anhedonia induced by bilateral 6-OHDA infusion into the substantia nigra pars compacta in rats: Therapeutic implications for Parkinson's disease.
    Behavioural brain research, 2018, 04-16, Volume: 342

    Topics: Anhedonia; Animals; Depression; Disease Models, Animal; Gait; Imipramine; Ketamine; Male; Nerve Dege

2018
Guanosine prevents depressive-like behaviors in rats following bilateral dorsolateral striatum lesion induced by 6-hydroxydopamine.
    Behavioural brain research, 2019, 10-17, Volume: 372

    Topics: Anhedonia; Animals; Brain; Corpus Striatum; Depression; Disease Models, Animal; Dopamine; Guanosine;

2019
The nonsteroidal antiinflammatory drug piroxicam reverses the onset of depressive-like behavior in 6-OHDA animal model of Parkinson's disease.
    Neuroscience, 2015, Aug-06, Volume: 300

    Topics: Anhedonia; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents; Depressive Disor

2015
Temporal Dissociation of Striatum and Prefrontal Cortex Uncouples Anhedonia and Defense Behaviors Relevant to Depression in 6-OHDA-Lesioned Rats.
    Molecular neurobiology, 2016, Volume: 53, Issue:6

    Topics: Anhedonia; Animals; Behavior, Animal; Corpus Striatum; Depression; Dopamine Plasma Membrane Transpor

2016