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oxidopamine and Alloxan Diabetes

oxidopamine has been researched along with Alloxan Diabetes in 15 studies

Oxidopamine: A neurotransmitter analogue that depletes noradrenergic stores in nerve endings and induces a reduction of dopamine levels in the brain. Its mechanism of action is related to the production of cytolytic free-radicals.
oxidopamine : A benzenetriol that is phenethylamine in which the hydrogens at positions 2, 4, and 5 on the phenyl ring are replaced by hydroxy groups. It occurs naturally in human urine, but is also produced as a metabolite of the drug DOPA (used for the treatment of Parkinson's disease).

Research Excerpts

ExcerptRelevanceReference
"During the early phase of scar formation/healing, the density of GAP43/nestin(+) fibres innervating the peri-infarct/infarct region was significantly increased, whereas neurofilament-M/nestin(+) fibres were absent."1.39The neurogenic response of cardiac resident nestin(+) cells was associated with GAP43 upregulation and abrogated in a setting of type I diabetes. ( Calderone, A; Chabot, A; Duquette, N; Hertig, V; Meus, MA, 2013)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19904 (26.67)18.7374
1990's6 (40.00)18.2507
2000's3 (20.00)29.6817
2010's2 (13.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sharma, S1
Taliyan, R1
Chabot, A1
Meus, MA1
Hertig, V1
Duquette, N1
Calderone, A1
Omiya, Y1
Suzuki, Y1
Yuzurihara, M1
Murata, M1
Aburada, M1
Kase, Y1
Takeda, S1
Cohen, G1
Heikkila, RE1
Pelleymounter, MA1
Lorden, JF1
Mayer, JH1
Clarke, SA1
Wilson, HF1
Tomlinson, DR3
Ahlgren, SC1
Levine, JD1
Wallace, W1
Ahlers, ST1
Gotlib, J1
Bragin, V1
Sugar, J1
Gluck, R1
Shea, PA1
Davis, KL1
Haroutunian, V1
Liu, J1
Wang, KM1
He, LZ1
Cao, DY1
Saitoh, A1
Morita, K1
Sodeyama, M1
Kamei, J1
Vo, PA2
Kvist-Reimer, M1
Sundler, F1
Ahrén, B1
Van der Zee, CE1
Van den Buuse, M1
Gispen, WH1
Fedorak, RN1
Chang, EB1
Madara, JL1
Field, M1

Other Studies

15 other studies available for oxidopamine and Alloxan Diabetes

ArticleYear
High fat diet feeding induced insulin resistance exacerbates 6-OHDA mediated neurotoxicity and behavioral abnormalities in rats.
    Behavioural brain research, 2018, 10-01, Volume: 351

    Topics: Animals; Corpus Striatum; Diabetes Mellitus, Experimental; Diet, High-Fat; Inflammation; Insulin Res

2018
The neurogenic response of cardiac resident nestin(+) cells was associated with GAP43 upregulation and abrogated in a setting of type I diabetes.
    Cardiovascular diabetology, 2013, Aug-12, Volume: 12

    Topics: Animals; Cicatrix; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Fibrosis; GAP-43 Prot

2013
Antinociceptive effect of shakuyakukanzoto, a Kampo medicine, in diabetic mice.
    Journal of pharmacological sciences, 2005, Volume: 99, Issue:4

    Topics: Adrenergic alpha-Antagonists; Analgesics; Animals; Diabetes Mellitus, Experimental; Dose-Response Re

2005
Alloxan and 6-hydroxydopamine: cellular toxins.
    Methods in enzymology, 1984, Volume: 105

    Topics: Alloxan; Animals; Blood Glucose; Brain; Diabetes Mellitus, Experimental; Free Radicals; Heart Atria;

1984
Feeding, activity, and body temperature following 6-hydroxydopamine lesions in diabetes (db/db) mice.
    Behavioral neuroscience, 1983, Volume: 97, Issue:5

    Topics: Animals; Body Composition; Body Temperature; Body Weight; Brain; Catecholamines; Diabetes Mellitus,

1983
The regrowth of right atrial noradrenergic nerves after 6-hydroxydopamine in genetically diabetic mice; effects of insulin treatment.
    Journal of autonomic pharmacology, 1982, Volume: 2, Issue:3

    Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Heart; Heart Atria; Heart Rate; Hyd

1982
Mechanical hyperalgesia in streptozotocin-diabetic rats is not sympathetically maintained.
    Brain research, 1993, Jul-09, Volume: 616, Issue:1-2

    Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Ganglia, Sympathetic; Hyperalgesia;

1993
Amyloid precursor protein in the cerebral cortex is rapidly and persistently induced by loss of subcortical innervation.
    Proceedings of the National Academy of Sciences of the United States of America, 1993, Sep-15, Volume: 90, Issue:18

    Topics: 5,7-Dihydroxytryptamine; Acetylcholine; Actins; Afferent Pathways; Amyloid beta-Protein Precursor; A

1993
[Effects of sympathetic efferent in diabetic hyperalgesia in rat].
    Sheng li xue bao : [Acta physiologica Sinica], 1996, Volume: 48, Issue:6

    Topics: Alprostadil; Animals; Diabetes Mellitus, Experimental; Dinoprostone; Efferent Pathways; Ganglia, Sym

1996
Effects of the experimental diabetes on dopamine D1 receptor-mediated locomotor-enhancing activity in mice.
    Pharmacology, biochemistry, and behavior, 1998, Volume: 60, Issue:1

    Topics: Animals; Benzazepines; Brain; Cocaine; Diabetes Mellitus, Experimental; Dopamine Agonists; Dopamine

1998
The regeneration of peripheral noradrenergic nerves after chemical sympathectomy in diabetic rats: effects of nerve growth factor.
    Experimental neurology, 1999, Volume: 157, Issue:1

    Topics: Animals; Atrial Function, Right; Diabetes Mellitus, Experimental; Electric Stimulation; Heart Atria;

1999
Effects of nerve growth factor on expression of GAP-43 in right atria after sympathectomy in diabetic rats.
    Diabetes, obesity & metabolism, 2001, Volume: 3, Issue:5

    Topics: Administration, Oral; Animals; Diabetes Mellitus, Experimental; GAP-43 Protein; Heart Atria; Immunoh

2001
Effects of chemical sympathectomy by means of 6-hydroxydopamine on insulin secretion and islet morphology in alloxan-diabetic mice.
    Cell and tissue research, 2002, Volume: 307, Issue:2

    Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Female; Gene Expression; Insul

2002
Beneficial effect of an ACTH-(4-9) analog on peripheral neuropathy and blood pressure response to tyramine in streptozocin diabetic rats.
    European journal of pharmacology, 1990, Feb-27, Volume: 177, Issue:3

    Topics: Adrenocorticotropic Hormone; Animals; Blood Pressure; Diabetes Mellitus, Experimental; Diabetic Neur

1990
Intestinal adaptation to diabetes. Altered Na-dependent nutrient absorption in streptozocin-treated chronically diabetic rats.
    The Journal of clinical investigation, 1987, Volume: 79, Issue:6

    Topics: 3-O-Methylglucose; Alanine; Animals; Carrier Proteins; Diabetes Mellitus, Experimental; Hydroxydopam

1987