oxidopamine has been researched along with Age-Related Memory Disorders in 26 studies
Oxidopamine: A neurotransmitter analogue that depletes noradrenergic stores in nerve endings and induces a reduction of dopamine levels in the brain. Its mechanism of action is related to the production of cytolytic free-radicals.
oxidopamine : A benzenetriol that is phenethylamine in which the hydrogens at positions 2, 4, and 5 on the phenyl ring are replaced by hydroxy groups. It occurs naturally in human urine, but is also produced as a metabolite of the drug DOPA (used for the treatment of Parkinson's disease).
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of this study was to evaluate etazolate against depression-like behavior and, learning and memory impairment induced by 6- hydroxydopamine (6-OHDA) rat model of Parkinson's disease (PD)." | 7.88 | Beneficial effect of etazolate on depression-like behavior and, learning, and memory impairment in a model of Parkinson's disease. ( Abuirmeileh, AN; Alzoubi, KH; Mokhemer, E, 2018) |
| " In this study, we investigated the effects of aging-associated formaldehyde (FA) on the inactivation of NE in vitro and in vivo, and on memory behaviors in rodents." | 7.81 | Aging-associated formaldehyde-induced norepinephrine deficiency contributes to age-related memory decline. ( Jia, J; Jiang, C; Lv, J; Mei, Y; Tong, Z; Wan, Y; Wang, X; Yang, X, 2015) |
| "The aim of this study was to evaluate etazolate against depression-like behavior and, learning and memory impairment induced by 6- hydroxydopamine (6-OHDA) rat model of Parkinson's disease (PD)." | 3.88 | Beneficial effect of etazolate on depression-like behavior and, learning, and memory impairment in a model of Parkinson's disease. ( Abuirmeileh, AN; Alzoubi, KH; Mokhemer, E, 2018) |
| " In this study, we investigated the effects of aging-associated formaldehyde (FA) on the inactivation of NE in vitro and in vivo, and on memory behaviors in rodents." | 3.81 | Aging-associated formaldehyde-induced norepinephrine deficiency contributes to age-related memory decline. ( Jia, J; Jiang, C; Lv, J; Mei, Y; Tong, Z; Wan, Y; Wang, X; Yang, X, 2015) |
| "Parkinson's disease is characterized by neurodegeneration and learning deficiency." | 1.51 | The effect of preventive exercise on the neuroprotection in 6-hydroxydopamine-lesioned rat brain. ( Alaei, H; Esfarjani, F; Marandi, SM; Rezaee, Z, 2019) |
| "Manganese (Mn) is an essential nutrient especially during development, but Mn overexposure (MnOE) produces long-term cognitive deficits." | 1.51 | Effects of Preweaning Manganese in Combination with Adult Striatal Dopamine Lesions on Monoamines, BDNF, TrkB, and Cognitive Function in Sprague-Dawley Rats. ( Bailey, RA; Gutierrez, A; Hemmerle, AM; Hufgard, JR; Kyser, TL; Seroogy, KB; Vorhees, CV; Williams, MT, 2019) |
| "Although patients with Parkinson's disease show impairments in cognitive performance even at the early stage of the disease, the synaptic mechanisms underlying cognitive impairment in this pathology are unknown." | 1.38 | Mechanisms underlying the impairment of hippocampal long-term potentiation and memory in experimental Parkinson's disease. ( Calabresi, P; Costa, C; de Iure, A; Di Filippo, M; Di Luca, M; Gardoni, F; Ghiglieri, V; Latagliata, EC; Marti, M; Morari, M; Pascucci, T; Pendolino, V; Picconi, B; Puglisi-Allegra, S; Sgobio, C; Siliquini, S; Spillantini, MG; Tantucci, M; Tozzi, A, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (7.69) | 18.2507 |
| 2000's | 4 (15.38) | 29.6817 |
| 2010's | 18 (69.23) | 24.3611 |
| 2020's | 2 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Haghparast, E | 1 |
| Sheibani, V | 1 |
| Komeili, G | 1 |
| Chahkandi, M | 1 |
| Rad, NS | 1 |
| Rezaee, Z | 1 |
| Marandi, SM | 1 |
| Alaei, H | 3 |
| Esfarjani, F | 1 |
| Barón-Quiroz, K | 1 |
| García-Ramirez, M | 1 |
| Chuc-Meza, E | 1 |
| Dallé, E | 1 |
| Daniels, WMU | 1 |
| Mabandla, MV | 1 |
| Haddadi, H | 1 |
| Rajaei, Z | 2 |
| Shahidani, S | 1 |
| Alzoubi, KH | 1 |
| Mokhemer, E | 1 |
| Abuirmeileh, AN | 1 |
| Loiodice, S | 1 |
| Wing Young, H | 1 |
| Rion, B | 1 |
| Méot, B | 1 |
| Montagne, P | 1 |
| Denibaud, AS | 1 |
| Viel, R | 1 |
| Drieu La Rochelle, C | 1 |
| Bailey, RA | 1 |
| Gutierrez, A | 2 |
| Kyser, TL | 1 |
| Hemmerle, AM | 1 |
| Hufgard, JR | 1 |
| Seroogy, KB | 2 |
| Vorhees, CV | 2 |
| Williams, MT | 2 |
| Kadowaki Horita, T | 1 |
| Kobayashi, M | 1 |
| Mori, A | 1 |
| Jenner, P | 1 |
| Kanda, T | 1 |
| Carmo, MR | 1 |
| Menezes, AP | 1 |
| Nunes, AC | 1 |
| Pliássova, A | 1 |
| Rolo, AP | 1 |
| Palmeira, CM | 1 |
| Cunha, RA | 2 |
| Canas, PM | 1 |
| Andrade, GM | 1 |
| Ramírez-García, G | 1 |
| Palafox-Sánchez, V | 1 |
| Limón, ID | 1 |
| Mei, Y | 1 |
| Jiang, C | 1 |
| Wan, Y | 1 |
| Lv, J | 1 |
| Jia, J | 1 |
| Wang, X | 1 |
| Yang, X | 1 |
| Tong, Z | 1 |
| Matheus, FC | 1 |
| Rial, D | 1 |
| Real, JI | 1 |
| Lemos, C | 1 |
| Ben, J | 1 |
| Guaita, GO | 1 |
| Pita, IR | 1 |
| Sequeira, AC | 1 |
| Pereira, FC | 1 |
| Walz, R | 1 |
| Takahashi, RN | 1 |
| Bertoglio, LJ | 1 |
| Da Cunha, C | 1 |
| Prediger, RD | 1 |
| Braun, AA | 1 |
| Amos-Kroohs, RM | 1 |
| Lundgren, KH | 1 |
| Hosseini, M | 1 |
| De Leonibus, E | 1 |
| Managò, F | 1 |
| Giordani, F | 1 |
| Petrosino, F | 1 |
| Lopez, S | 1 |
| Oliverio, A | 1 |
| Amalric, M | 1 |
| Mele, A | 1 |
| Lex, B | 1 |
| Sommer, S | 1 |
| Hauber, W | 1 |
| Foyet, HS | 1 |
| Hritcu, L | 2 |
| Ciobica, A | 2 |
| Stefan, M | 2 |
| Kamtchouing, P | 1 |
| Cojocaru, D | 1 |
| Mihasan, M | 1 |
| Palamiuc, L | 1 |
| Nabeshima, T | 1 |
| Matsumoto, Y | 1 |
| Murakami, H | 1 |
| Hattori, N | 1 |
| Yoshimoto, K | 1 |
| Asano, S | 1 |
| Inden, M | 1 |
| Costa, C | 1 |
| Sgobio, C | 1 |
| Siliquini, S | 1 |
| Tozzi, A | 1 |
| Tantucci, M | 1 |
| Ghiglieri, V | 1 |
| Di Filippo, M | 1 |
| Pendolino, V | 1 |
| de Iure, A | 1 |
| Marti, M | 1 |
| Morari, M | 1 |
| Spillantini, MG | 1 |
| Latagliata, EC | 1 |
| Pascucci, T | 1 |
| Puglisi-Allegra, S | 1 |
| Gardoni, F | 1 |
| Di Luca, M | 1 |
| Picconi, B | 1 |
| Calabresi, P | 1 |
| Ridley, RM | 1 |
| Cummings, RM | 1 |
| Leow-Dyke, A | 1 |
| Baker, HF | 1 |
| Clinton, SM | 1 |
| Sucharski, IL | 1 |
| Finlay, JM | 1 |
| Fang, X | 1 |
| Sugiyama, K | 1 |
| Akamine, S | 1 |
| Namba, H | 1 |
| Genkova-Papazova, MG | 1 |
| Stancheva, SL | 1 |
| Alova, LG | 1 |
| Lazarova-Bakarova, MB | 1 |
| Grigoryan, G | 1 |
| Hodges, H | 1 |
| Mitchell, S | 1 |
| Sinden, JD | 1 |
| Gray, JA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Role of Saffron and Chamomile and Their Active Compounds in the Management of Parkinson Disease in the Context of Psychometric and Biochemical Measures[NCT05696665] | 120 participants (Anticipated) | Interventional | 2022-07-05 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for oxidopamine and Age-Related Memory Disorders
| Article | Year |
|---|---|
6-OHDA lesions of the nucleus accumbens accentuate memory deficits in animals with lesions to the forebrain cholinergic projection system: effects of nicotine administration on learning and memory in the water maze.
Topics: Animals; Choline O-Acetyltransferase; Dopamine; Hippocampus; Learning; Male; Memory; Memory Disorder | 1996 |
25 other studies available for oxidopamine and Age-Related Memory Disorders
| Article | Year |
|---|---|
The Effects of Chronic Marijuana Administration on 6-OHDA-Induced Learning & Memory Impairment and Hippocampal Dopamine and Cannabinoid Receptors Interaction in Male Rats.
Topics: Animals; Cannabis; Cognition; Dopamine; Hippocampus; Male; Memory Disorders; Oxidopamine; Rats; Rece | 2023 |
The effect of preventive exercise on the neuroprotection in 6-hydroxydopamine-lesioned rat brain.
Topics: Animals; Brain; Brain-Derived Neurotrophic Factor; Fibronectins; Male; Maze Learning; Memory Disorde | 2019 |
Dopaminergic denervation of the globus pallidus produces short-memory impairment in rats.
Topics: Animals; Denervation; Dopamine; Globus Pallidus; Male; Memory Disorders; Memory, Short-Term; Oxidopa | 2021 |
Fluvoxamine maleate effects on dopamine signaling in the prefrontal cortex of stressed Parkinsonian rats: Implications for learning and memory.
Topics: Animals; Corticosterone; Dopamine; Fluvoxamine; Learning; Learning Disabilities; Lipid Peroxidation; | 2017 |
Chronic treatment with carvacrol improves passive avoidance memory in a rat model of Parkinson's disease.
Topics: Animals; Antioxidants; Antiparkinson Agents; Cymenes; Disease Models, Animal; Lipid Peroxidation; Ma | 2018 |
Beneficial effect of etazolate on depression-like behavior and, learning, and memory impairment in a model of Parkinson's disease.
Topics: Animals; Antiparkinson Agents; Depression; Etazolate; Hippocampus; Learning Disabilities; Male; Memo | 2018 |
Implication of nigral dopaminergic lesion and repeated L-dopa exposure in neuropsychiatric symptoms of Parkinson's disease.
Topics: Amphetamine; Animals; Antiparkinson Agents; Anxiety; Benserazide; Disease Models, Animal; Dopamine; | 2019 |
Effects of Preweaning Manganese in Combination with Adult Striatal Dopamine Lesions on Monoamines, BDNF, TrkB, and Cognitive Function in Sprague-Dawley Rats.
Topics: Animals; Brain; Brain-Derived Neurotrophic Factor; Cognition; Cognitive Dysfunction; Dopamine; Femal | 2019 |
Effects of the adenosine A2A antagonist istradefylline on cognitive performance in rats with a 6-OHDA lesion in prefrontal cortex.
Topics: Adenosine A2 Receptor Antagonists; Animals; Cognition; Cognition Disorders; Disease Models, Animal; | 2013 |
The P2X7 receptor antagonist Brilliant Blue G attenuates contralateral rotations in a rat model of Parkinsonism through a combined control of synaptotoxicity, neurotoxicity and gliosis.
Topics: Animals; Avoidance Learning; Brain; Cell Line, Tumor; Disease Models, Animal; Exploratory Behavior; | 2014 |
Nitrosative and cognitive effects of chronic L-DOPA administration in rats with intra-nigral 6-OHDA lesion.
Topics: Animals; Antiparkinson Agents; Astrocytes; Carbidopa; Corpus Striatum; Gliosis; Levodopa; Male; Maze | 2015 |
Aging-associated formaldehyde-induced norepinephrine deficiency contributes to age-related memory decline.
Topics: Aging; Animals; Autonomic Nervous System Diseases; Dopamine beta-Hydroxylase; Formaldehyde; Hippocam | 2015 |
Decreased synaptic plasticity in the medial prefrontal cortex underlies short-term memory deficits in 6-OHDA-lesioned rats.
Topics: Animals; Discrimination, Psychological; Double-Blind Method; Long-Term Potentiation; Male; Maze Lear | 2016 |
6-Hydroxydopamine-Induced Dopamine Reductions in the Nucleus Accumbens, but not the Medial Prefrontal Cortex, Impair Cincinnati Water Maze Egocentric and Morris Water Maze Allocentric Navigation in Male Sprague-Dawley Rats.
Topics: Animals; Cohort Studies; Dopamine; Learning Disabilities; Male; Maze Learning; Memory Disorders; Mod | 2016 |
Effects of crocin on brain oxidative damage and aversive memory in a 6-OHDA model of Parkinson's disease.
Topics: Animals; Antioxidants; Carotenoids; Cerebral Cortex; Disease Models, Animal; Glutathione Peroxidase; | 2016 |
Metabotropic glutamate receptors 5 blockade reverses spatial memory deficits in a mouse model of Parkinson's disease.
Topics: Animals; Association Learning; Corpus Striatum; Disease Models, Animal; Dose-Response Relationship, | 2009 |
The role of dopamine in the dorsomedial striatum in place and response learning.
Topics: Animals; Dopamine; Learning; Learning Disabilities; Male; Maze Learning; Memory; Memory Disorders; N | 2011 |
Methanolic extract of Hibiscus asper leaves improves spatial memory deficits in the 6-hydroxydopamine-lesion rodent model of Parkinson's disease.
Topics: Animals; Antioxidants; Ethnopharmacology; Hibiscus; Male; Maze Learning; Medicine, African Tradition | 2011 |
Spatial memory deficits and oxidative stress damage following exposure to lipopolysaccharide in a rodent model of Parkinson's disease.
Topics: Animals; Disease Models, Animal; Lipopolysaccharides; Male; Memory Disorders; Neurotoxins; Oxidative | 2011 |
Excessive expression of hippocampal ezrin is induced by intrastriatal injection of 6-hydroxydopamine.
Topics: Adrenergic Agents; Animals; Cytoskeletal Proteins; Dopamine; Hippocampus; Male; Memory Disorders; Mi | 2011 |
Mechanisms underlying the impairment of hippocampal long-term potentiation and memory in experimental Parkinson's disease.
Topics: alpha-Synuclein; Analysis of Variance; Animals; Antiparkinson Agents; Benserazide; Biophysical Pheno | 2012 |
Neglect of memory after dopaminergic lesions in monkeys.
Topics: Analysis of Variance; Animals; Behavior, Animal; Brain Injuries; Callithrix; Catheter Ablation; Disc | 2006 |
Desipramine attenuates working memory impairments induced by partial loss of catecholamines in the rat medial prefrontal cortex.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antidepressive Agents; Catecholamines; Desipramine; Dopamin | 2006 |
The stepping test and its learning process in different degrees of unilateral striatal lesions by 6-hydroxydopamine in rats.
Topics: Animals; Corpus Striatum; Denervation; Disease Models, Animal; Dopamine; Dose-Response Relationship, | 2006 |
Adafenoxate abolishes the amnesia induced by neonatal 6-hydroxydopamine treatment in rats.
Topics: Amnesia; Animals; Animals, Newborn; Avoidance Learning; Biogenic Amines; Brain; Cognition; Male; Mec | 1993 |