oxidopamine has been researched along with Acute Confusional Senile Dementia in 14 studies
Oxidopamine: A neurotransmitter analogue that depletes noradrenergic stores in nerve endings and induces a reduction of dopamine levels in the brain. Its mechanism of action is related to the production of cytolytic free-radicals.
oxidopamine : A benzenetriol that is phenethylamine in which the hydrogens at positions 2, 4, and 5 on the phenyl ring are replaced by hydroxy groups. It occurs naturally in human urine, but is also produced as a metabolite of the drug DOPA (used for the treatment of Parkinson's disease).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Although alpha-synuclein is the main structural component of the insoluble filaments that form Lewy bodies in Parkinson disease (PD), its physiological function and exact role in neuronal death remain poorly understood." | 3.73 | Proteolytic cleavage of extracellular secreted {alpha}-synuclein via matrix metalloproteinases. ( Chung, KC; Kim, J; Lee, CH; Lee, HJ; Lee, ST; Oh, YJ; Paik, SR; Park, SM; Sung, JY; Um, JW, 2005) |
| "Parkinson's disease (PD) and Alzheimer's disease (AD) are the most common chronic neurodegenerative disorders, characterized by motoric dysfunction or cognitive decline in the early stage, respectively, but often by both symptoms in the advanced stage." | 2.66 | Shared cerebral metabolic pathology in non-transgenic animal models of Alzheimer's and Parkinson's disease. ( Barilar, JO; Homolak, J; Knezovic, A; Perhoc, AB; Riederer, P; Salkovic-Petrisic, M, 2020) |
| "Alzheimer's disease (AD) and Parkinson's disease (PD) are the two most common neurodegenerative diseases that are presently incurable." | 1.91 | Small-Molecule Cdc25A Inhibitors Protect Neuronal Cells from Death Evoked by NGF Deprivation and 6-Hydroxydopamine. ( Banerji, B; Biswas, SC; Das, AK; Pramanik, SK; Sanphui, P, 2023) |
| "Parkinson's disease and Alzheimer's disease (AD) are recognized to coexist on a spectrum of neurodegeneration, and it has been proposed that molecular interactions among pathogenic proteins are a basis for the overlap between these two diseases." | 1.42 | Partial depletion of striatal dopamine enhances penetrance of cognitive deficits in a transgenic mouse model of Alzheimer's disease. ( Cudaback, E; Darvas, M; Jorstad, NL; Keene, CD; Melief, EJ; Montine, KS; Montine, TJ; Postupna, N; Sherfield, E; Wilson, A, 2015) |
| "[3H]Vesamicol binding was characterized in human brain post mortem." | 1.28 | Choline acetyltransferase activity and [3H]vesamicol binding in the temporal cortex of patients with Alzheimer's disease, Parkinson's disease, and rats with basal forebrain lesions. ( Agid, Y; Brice, A; Duyckaerts, C; Hauw, JJ; LeMoal, M; Mayo, W; Ruberg, M; Simon, H, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (28.57) | 18.2507 |
| 2000's | 2 (14.29) | 29.6817 |
| 2010's | 2 (14.29) | 24.3611 |
| 2020's | 6 (42.86) | 2.80 |
| Authors | Studies |
|---|---|
| Fan, Y | 1 |
| Li, M | 1 |
| Wu, C | 1 |
| Wu, Y | 1 |
| Han, J | 1 |
| Wu, P | 1 |
| Huang, Z | 1 |
| Wang, Q | 1 |
| Zhao, L | 1 |
| Chen, D | 1 |
| Zhu, M | 1 |
| Pramanik, SK | 1 |
| Sanphui, P | 1 |
| Das, AK | 1 |
| Banerji, B | 1 |
| Biswas, SC | 1 |
| Sun, L | 1 |
| Zhang, T | 1 |
| Xiu, W | 1 |
| Cao, W | 1 |
| He, M | 1 |
| Sun, W | 1 |
| Zhao, W | 1 |
| Al Mamun, A | 1 |
| Uddin, MS | 1 |
| Barilar, JO | 1 |
| Knezovic, A | 1 |
| Perhoc, AB | 1 |
| Homolak, J | 1 |
| Riederer, P | 1 |
| Salkovic-Petrisic, M | 1 |
| Lepelletier, FX | 1 |
| Vandesquille, M | 1 |
| Asselin, MC | 1 |
| Prenant, C | 1 |
| Robinson, AC | 1 |
| Mann, DMA | 1 |
| Green, M | 1 |
| Barnett, E | 1 |
| Banister, SD | 1 |
| Mottinelli, M | 1 |
| Mesangeau, C | 1 |
| McCurdy, CR | 1 |
| Fricke, IB | 1 |
| Jacobs, AH | 1 |
| Kassiou, M | 1 |
| Boutin, H | 1 |
| Xu, Y | 1 |
| Wei, H | 1 |
| Wang, J | 1 |
| Wang, W | 1 |
| Gao, J | 1 |
| Melief, EJ | 1 |
| Cudaback, E | 1 |
| Jorstad, NL | 1 |
| Sherfield, E | 1 |
| Postupna, N | 1 |
| Wilson, A | 1 |
| Darvas, M | 1 |
| Montine, KS | 1 |
| Keene, CD | 1 |
| Montine, TJ | 1 |
| Ji, B | 1 |
| Maeda, J | 1 |
| Sawada, M | 1 |
| Ono, M | 1 |
| Okauchi, T | 1 |
| Inaji, M | 1 |
| Zhang, MR | 1 |
| Suzuki, K | 1 |
| Ando, K | 1 |
| Staufenbiel, M | 1 |
| Trojanowski, JQ | 1 |
| Lee, VM | 1 |
| Higuchi, M | 1 |
| Suhara, T | 1 |
| Sung, JY | 1 |
| Park, SM | 1 |
| Lee, CH | 1 |
| Um, JW | 1 |
| Lee, HJ | 1 |
| Kim, J | 1 |
| Oh, YJ | 1 |
| Lee, ST | 1 |
| Paik, SR | 1 |
| Chung, KC | 1 |
| Arenas, E | 1 |
| Persson, H | 1 |
| Mazziotti, M | 1 |
| Perlmutter, DH | 1 |
| Haroutunian, V | 1 |
| Santucci, AC | 1 |
| Davis, KL | 1 |
| Ruberg, M | 1 |
| Mayo, W | 1 |
| Brice, A | 1 |
| Duyckaerts, C | 1 |
| Hauw, JJ | 1 |
| Simon, H | 1 |
| LeMoal, M | 1 |
| Agid, Y | 1 |
1 review available for oxidopamine and Acute Confusional Senile Dementia
| Article | Year |
|---|---|
Shared cerebral metabolic pathology in non-transgenic animal models of Alzheimer's and Parkinson's disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Alzheimer Disease; Animals; Disease Models, Animal; Do | 2020 |
13 other studies available for oxidopamine and Acute Confusional Senile Dementia
| Article | Year |
|---|---|
Chronic Cerebral Hypoperfusion Aggravates Parkinson's Disease Dementia-Like Symptoms and Pathology in 6-OHDA-Lesioned Rat through Interfering with Sphingolipid Metabolism.
Topics: Alzheimer Disease; Animals; Brain Ischemia; Dementia; Disease Models, Animal; Lipid Metabolism; Male | 2022 |
Small-Molecule Cdc25A Inhibitors Protect Neuronal Cells from Death Evoked by NGF Deprivation and 6-Hydroxydopamine.
Topics: Alzheimer Disease; cdc25 Phosphatases; Dopamine; Humans; Nerve Growth Factor; Neurodegenerative Dise | 2023 |
MiR-107 overexpression attenuates neurotoxicity induced by 6-hydroxydopamine both in vitro and in vivo.
Topics: Alzheimer Disease; Animals; Apoptosis Regulatory Proteins; Brain; Cell Death; Cell Line, Tumor; Dise | 2020 |
KDS2010: A Potent Highly Selective and Reversible MAO-B Inhibitor for Alzheimer's Disease.
Topics: alpha-Synuclein; Alzheimer Disease; Animals; Biological Transport; Blood-Brain Barrier; Drug Design; | 2020 |
Evaluation of
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Animals; Autoradiography; Brain; Disease Models, Animal; | 2020 |
Synthesis of andrographolide analogues and their neuroprotection and neurite outgrowth-promoting activities.
Topics: Alzheimer Disease; Animals; Anti-Inflammatory Agents; Cell Line, Transformed; Diterpenes; Gene Expre | 2019 |
Partial depletion of striatal dopamine enhances penetrance of cognitive deficits in a transgenic mouse model of Alzheimer's disease.
Topics: Adrenergic Agents; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Analysi | 2015 |
Imaging of peripheral benzodiazepine receptor expression as biomarkers of detrimental versus beneficial glial responses in mouse models of Alzheimer's and other CNS pathologies.
Topics: Acetamides; Alzheimer Disease; Amyloid beta-Protein Precursor; Analysis of Variance; Animals; Cell L | 2008 |
Proteolytic cleavage of extracellular secreted {alpha}-synuclein via matrix metalloproteinases.
Topics: alpha-Synuclein; Alzheimer Disease; Amyloid beta-Peptides; Animals; Blotting, Western; Catalytic Dom | 2005 |
Neurotrophin-3 prevents the death of adult central noradrenergic neurons in vivo.
Topics: Alzheimer Disease; Animals; Cell Death; Cell Line; Cell Survival; Cell Transplantation; Culture Medi | 1994 |
Resistance to the apoptotic effect of aggregated amyloid-beta peptide in several different cell types including neuronal- and hepatoma-derived cell lines.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Antimycin A; Apoptosis; Cell Line; Cytotoxins; DN | 1998 |
Implications of multiple transmitter system lesions for cholinomimetic therapy in Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Avoidance Learning; Cerebral Cortex; Choline O-Ace | 1990 |
Choline acetyltransferase activity and [3H]vesamicol binding in the temporal cortex of patients with Alzheimer's disease, Parkinson's disease, and rats with basal forebrain lesions.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Animals; Brain Injuries; Choline O-Acetyltransferase; Fe | 1990 |