Page last updated: 2024-08-25

oxazolidin-2-one and Body Weight

oxazolidin-2-one has been researched along with Body Weight in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19903 (15.79)18.7374
1990's2 (10.53)18.2507
2000's1 (5.26)29.6817
2010's11 (57.89)24.3611
2020's2 (10.53)2.80

Authors

AuthorsStudies
Al Jalali, V; Bauer, M; Dorn, C; Jilma, B; Jorda, A; Lackner, E; Matzneller, P; Schörgenhofer, C; Wölf-Duchek, M; Wulkersdorfer, B; Zeitlinger, M1
Cao, G; Chen, Y; Guo, B; Li, L; Wu, H; Wu, J; Wu, X; Yuan, H; Zhang, J; Zhang, Y; Zhao, M1
Al-Huniti, N; Birmingham, B; Li, J; Lillieborg, S; Xu, H; Zhou, D; Zhou, W1
Hiraki, Y; Kamimura, H; Karube, Y; Matsumoto, K; Mizoguchi, A; Morita, K; To, H; Tsuji, Y; Yukawa, E1
Barreto, JN; Huang, DB; Morrow, LE; Puzniak, LA1
Itoh, Y; Murakami, N; Niwa, T; Ohmori, T; Ohta, H; Suzuki, A; Suzuki, T; Tsuchiya, M; Watanabe, T1
Furukawa, K; Natsumoto, B; Omata, F; Yokota, K1
Abe, S; Chiba, K; Cirincione, B; Grasela, TH; Ito, K; Suwa, T1
Cojutti, P; Cristini, F; Franceschi, L; Furlanut, M; Pea, F; Viale, P; Zamparini, E1
Bai, N; Cai, Y; Chai, D; Falagas, ME; Guo, D; Liang, B; Liu, Y; Vouloumanou, EK; Wang, R1
Antonelli, M; De Pascale, G; Fortuna, S; Navarra, P1
Bhalodi, AA; Kuti, JL; Nicolau, DP; Papasavas, PK; Tishler, DS1
Alegre, F; Banales, JM; Barbero, R; Carreño, N; Chang, HC; García, M; Herrero, I; Morán, A; Pérez-Vizcaíno, F; Prieto, J; Quiroga, J; Reboredo, M; Rodríguez-Ortigosa, CM; Sangro, B1
Bai, N; Cai, Y; Chai, D; Falagas, ME; Karageorgopoulos, DE; Liang, B; Wang, R1
Bodor, N; Burkett, HD; Faison, JH; Kohl, HH; Mora, EC; Wheatley, WB; Worley, SD1
Aoki, T; Chimoto, T; Hosokawa, S; Sagami, F; Sato, G; Sumigama, S; Tsukidate, K1
Bleyl, DW; Lewerenz, HJ; Schnaak, W1
Bleyl, DW; Lewerenz, HJ; Plass, R; Przybilski, H; Schnaak, W1
Bjeldanes, LF; Chang, Y1

Trials

4 trial(s) available for oxazolidin-2-one and Body Weight

ArticleYear
Population Pharmacokinetics Study of Contezolid (MRX-I), a Novel Oxazolidinone Antibacterial Agent, in Chinese Patients.
    Clinical therapeutics, 2020, Volume: 42, Issue:5

    Topics: Administration, Oral; Adolescent; Adult; Aged; Anti-Bacterial Agents; Body Weight; Female; Food-Drug Interactions; Healthy Volunteers; Humans; Male; Methicillin-Resistant Staphylococcus aureus; Middle Aged; Models, Biological; Monte Carlo Method; Oxazolidinones; Pyridones; Skin Diseases; Staphylococcal Infections; Young Adult

2020
Impact of weight on treatment efficacy and safety in complicated skin and skin structure infections and nosocomial pneumonia caused by methicillin-resistant Staphylococcus aureus.
    Clinical therapeutics, 2013, Volume: 35, Issue:10

    Topics: Acetamides; Adult; Aged; Anti-Bacterial Agents; Body Weight; Cross Infection; Dose-Response Relationship, Drug; Humans; Linezolid; Male; Methicillin-Resistant Staphylococcus aureus; Middle Aged; Oxazolidinones; Pneumonia, Staphylococcal; Staphylococcal Skin Infections; Treatment Outcome; Vancomycin

2013
Immediate hematological toxicity of linezolid in healthy volunteers with different body weight: a phase I clinical trial.
    The Journal of antibiotics, 2012, Volume: 65, Issue:4

    Topics: Acetamides; Adolescent; Adult; Anti-Infective Agents; Body Weight; Erythrocyte Count; Hemoglobins; Humans; Leukocyte Count; Linezolid; Male; Oxazolidinones; Platelet Count; Young Adult

2012
Weight-adjusted versus fixed dose of linezolid for Chinese healthy volunteers of higher and lower body weight: a Phase I pharmacokinetic and pharmacodynamic study.
    Expert opinion on investigational drugs, 2013, Volume: 22, Issue:3

    Topics: Acetamides; Administration, Intravenous; Adult; Anti-Infective Agents; Asian People; Body Weight; Dose-Response Relationship, Drug; Humans; Linezolid; Male; Monte Carlo Method; Oxazolidinones

2013

Other Studies

15 other study(ies) available for oxazolidin-2-one and Body Weight

ArticleYear
Influence of tedizolid on the cytokine response to the endotoxin challenge in healthy volunteers: a cross-over trial.
    The Journal of antimicrobial chemotherapy, 2022, 04-27, Volume: 77, Issue:5

    Topics: Anti-Bacterial Agents; Body Weight; Cross-Over Studies; Cytokines; Endotoxemia; Endotoxins; Female; Healthy Volunteers; Humans; Lipopolysaccharides; Male; Oxazolidinones; Tetrazoles

2022
Population Pharmacokinetic Analysis of Zolmitriptan and Its Metabolite in Adults and Adolescents to Support Dose Selection in Children With Migraine.
    Journal of clinical pharmacology, 2017, Volume: 57, Issue:10

    Topics: Administration, Intranasal; Adolescent; Adult; Body Weight; Child; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Migraine Disorders; Models, Biological; Oxazoles; Oxazolidinones; Serotonin 5-HT1 Receptor Agonists; Tryptamines; Young Adult

2017
Population pharmacokinetic analysis of linezolid in low body weight patients with renal dysfunction.
    Journal of clinical pharmacology, 2013, Volume: 53, Issue:9

    Topics: Acetamides; Adult; Aged; Aged, 80 and over; Alanine Transaminase; Anti-Bacterial Agents; Body Weight; Creatinine; Female; Glomerular Filtration Rate; Hemoglobins; Humans; Linezolid; Male; Methicillin-Resistant Staphylococcus aureus; Middle Aged; Models, Biological; Oxazolidinones; Renal Insufficiency; Staphylococcal Infections

2013
Reduction of linezolid-associated thrombocytopenia by the dose adjustment based on the risk factors such as basal platelet count and body weight.
    Diagnostic microbiology and infectious disease, 2014, Volume: 79, Issue:1

    Topics: Acetamides; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Body Weight; Female; Humans; Linezolid; Male; Middle Aged; Oxazolidinones; Platelet Count; Regression Analysis; Risk Factors; Thrombocytopenia

2014
Risk factors for linezolid-associated thrombocytopenia in adult patients.
    Infection, 2014, Volume: 42, Issue:6

    Topics: Acetamides; Aged; Aged, 80 and over; Analysis of Variance; Body Weight; Female; Humans; Japan; Linezolid; Male; Middle Aged; Oxazolidinones; Retrospective Studies; Thrombocytopenia

2014
Population pharmacokinetic analysis of linezolid in patients with infectious disease: application to lower body weight and elderly patients.
    Journal of clinical pharmacology, 2009, Volume: 49, Issue:9

    Topics: Acetamides; Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Anti-Bacterial Agents; Asian People; Body Weight; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Communicable Diseases; Female; Humans; Japan; Linezolid; Male; Middle Aged; Models, Biological; Nonlinear Dynamics; Oxazolidinones; Sex Factors; White People; Young Adult

2009
Therapeutic drug monitoring of linezolid: a retrospective monocentric analysis.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:11

    Topics: Acetamides; Adult; Aged; Anti-Bacterial Agents; Body Weight; Drug Monitoring; Female; Humans; Linezolid; Male; Middle Aged; Oxazolidinones; Retrospective Studies

2010
Linezolid use in ventilator-associated pneumonia: look at the body weight of your patient!
    Minerva anestesiologica, 2012, Volume: 78, Issue:12

    Topics: Acetamides; Anti-Infective Agents; Area Under Curve; Body Weight; Humans; Linezolid; Methicillin-Resistant Staphylococcus aureus; Obesity; Oxazolidinones; Pneumonia, Ventilator-Associated; Staphylococcal Infections

2012
Pharmacokinetics of intravenous linezolid in moderately to morbidly obese adults.
    Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:3

    Topics: Acetamides; Adult; Area Under Curve; Body Mass Index; Body Weight; Drug Dosage Calculations; Female; Humans; Injections, Intravenous; Linezolid; Male; Middle Aged; Obesity, Morbid; Oxazolidinones; Prospective Studies; Protein Synthesis Inhibitors; Severity of Illness Index

2013
Zolmitriptan: a novel portal hypotensive agent which synergizes with propranolol in lowering portal pressure.
    PloS one, 2013, Volume: 8, Issue:1

    Topics: Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Body Weight; Carbon Tetrachloride; Catecholamines; Common Bile Duct; Cyclic AMP; Drug Synergism; Drug Therapy, Combination; Hypertension, Portal; Infusions, Intravenous; Ligation; Liver Cirrhosis, Experimental; Lypressin; Mesenteric Artery, Superior; Oxazolidinones; Perfusion; Portal Pressure; Propranolol; Rats; Regional Blood Flow; Renal Artery; Splanchnic Circulation; Sympathectomy; Terlipressin; Tryptamines; Vasodilation

2013
Properties of a new chloramine disinfectant and detoxicant.
    Poultry science, 1982, Volume: 61, Issue:10

    Topics: Aflatoxin B1; Aflatoxins; Animals; Body Weight; Chickens; Disinfectants; Hydrogen-Ion Concentration; Oxazoles; Oxazolidinones; Water

1982
Toxicological response of rats to a novel monoamine oxidase type-A inhibitor, (5R)-3-[2-((1S)-3-cyano-1-hydroxypropyl)benzothiazol-6-yl]-5- methoxymethyl-2-oxazolidinone (E2011), orally administered for 13 weeks.
    The Journal of toxicological sciences, 1999, Volume: 24, Issue:3

    Topics: Administration, Oral; Animals; Benzothiazoles; Body Weight; Eating; Female; Glutathione S-Transferase pi; Glutathione Transferase; Harderian Gland; Hematologic Tests; Isoenzymes; Liver; Liver Neoplasms, Experimental; Male; Monoamine Oxidase Inhibitors; Organ Size; Oxazoles; Oxazolidinones; Precancerous Conditions; Rats; Rats, Sprague-Dawley; Salivation; Thiazoles

1999
Effects of 5-vinyloxazolidine-2-thione on lactating rats and their sucklings.
    Die Nahrung, 1992, Volume: 36, Issue:4

    Topics: Animals; Animals, Suckling; Antithyroid Agents; Body Weight; Female; Lactation; Leukocyte Count; Male; Organ Size; Oxazoles; Oxazolidinones; Rats; Rats, Wistar; Thyroid Gland

1992
[The subchronic toxicity of 5-vinyloxazolidine-2-thione in rats].
    Die Nahrung, 1989, Volume: 33, Issue:10

    Topics: Animals; Body Weight; Dose-Response Relationship, Drug; Drinking; Eating; Erythrocyte Count; Female; Leukocyte Count; Liver; Male; Organ Size; Oxazoles; Oxazolidinones; Plant Extracts; Rats; Sex Characteristics; Thymus Gland; Thyroid Gland

1989
Effects of dietary R-goitrin on hepatic and intestinal glutathione S-transferase, microsomal epoxide hydratase and ethoxycoumarin O-deethylase activities in the rat.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1985, Volume: 23, Issue:10

    Topics: 7-Alkoxycoumarin O-Dealkylase; Animals; Body Weight; Diet; Epoxide Hydrolases; Feeding Behavior; Glutathione Transferase; Intestine, Small; Liver; Male; Organ Size; Oxazoles; Oxazolidinones; Oxygenases; Rats; Rats, Inbred Strains

1985