Page last updated: 2024-08-21

oxazoles and Neoplasms

oxazoles has been researched along with Neoplasms in 56 studies

Research

Studies (56)

Timeframe	Studies, this research(%)	All Research%
pre-1990	10 (17.86)	18.7374
1990's	1 (1.79)	18.2507
2000's	14 (25.00)	29.6817
2010's	25 (44.64)	24.3611
2020's	6 (10.71)	2.80

Authors

Authors	Studies
Jaitak, V; Kaur, K; Kulkarni, S	1
Barcherini, V; Bastos, M; Carvalho, A; Carvalho, AL; Domingues, L; Dourado, DFAR; Fronza, G; Gomes, AS; Gomes, S; Loureiro, JB; Marcelo, F; Monti, P; Oliveira, C; Pinheiro, B; Ramos, H; Romão, MJ; Santos, MMM; Saraiva, L; Soares, J	1
de Vries, P; Forero-Torres, A; Kulukian, A; Lee, P; Peterson, S; Rosler, R; Taylor, J; Watson, D	1
Ameratunga, M; Aspegren, J; Bono, P; Braña, I; de Bono, JS; Korjamo, T; Plummer, R; Postel-Vinay, S; Snapir, A	1
Gao, J; Gao, S; Xu, M; Yao, C; Zhang, W; Zou, H	1
Ardizzone, A; Campolo, M; Casili, G; Cuzzocrea, S; Esposito, E; Filippone, A; Lanza, M; Mare, M; Memeo, L; Paterniti, I; Puglisi, C; Scuderi, SA	1
Geng, J; Li, Y; Najafov, A; Ofengeim, D; Ouchida, AT; Sun, X; Yu, Q; Yuan, J	1
Chen, S; Qi, C; Shen, Z; Wang, G; Wang, X; Williams, N; Yu, H	1
Connelly, MC; Guy, RK; Hobrath, JV; Mathew, B; Reynolds, RC	1
Cheng, C; Jia, Y; Jin, X; Liu, Y; Wang, G; Yao, L; Zhang, J; Zhou, F	1
Chan, HN; Li, HW; Li, Y; Poon, CY; Wong, MS; Xu, D	1
Gajek, A; Marczak, A; Oszczapowicz, I; Rogalska, A; Łukawska, M	1
Tang, YJ; Zhang, QY; Zhao, W	1
Jian, XH; Jiang, W; Li, D; Li, L; Lu, Y; Pan, HX; Pei, ZF; Tang, GL; Yang, MJ; Yin, Y	1
Chen, K; Li, JR; Li, X; Zhu, HL	1
Markle, MM; Murphy, KM; Nguyen, V; Wilkinson, W	1
Bowers, AA; Bradner, JE; Estiu, G; Guerra-Bubb, JM; Paranal, R; Smith, WB; Wiest, O; Williams, RM	1
Dargaville, TR; Hollier, BG; Hoogenboom, R; Shokoohmand, A	1
Doi, T	1
D'Orazi, G; Garufi, A	1
Eisenstein, M	1
Giordano, A; Morales, F	1
Abankwa, D; Aittokallio, T; Guzmán, C; Jaiswal, A; Lacey, E; Lectez, B; Najumudeen, AK; Oetken-Lindholm, C; Posada, IM; Siljamäki, E	1
Bultynck, G	1
Dong, L; Fennell, K; Franzblau, S; Hu, J; Kurt Dolence, E; Malouin, F; McKee-Dolence, J; Miller, MJ; Minnick, AA; Möllmann, U; Moraski, G; Roosenberg, JM; Vergne, A; Walz, AJ; Wu, C; Xu, Y; Zhu, H	1
Fujiki, H; Suganuma, M	1
Barthel, BL; Chan, DC; Coldren, CD; Koch, GG; Koch, TH; Polinkovsky, M; Rudnicki, DL; Sun, H; Zhang, Z	1
Johnson, EO; Kumar, D; Kumar, NM; Shah, K; Sundaree, S	1
Batrakova, EV; Bronich, TK; Jordan, R; Kabanov, AV; Li, S; Luxenhofer, R; Roques, C; Schulz, A	1
Fuller, RW; Gustafson, KR; McMahon, JB; Oku, N; Pannell, LK; Peach, ML; Takada, K; Wilson, JA	1
Liptrot, CH; Motti, CA; Nielson, JL; Ovenden, SPB; Tapiolas, DM; Willis, RH; Wright, AD	1
Crews, P; Jiang, HL; Luo, XH; Valeriote, FA; Wang, XZ; Wu, QX; Yang, JL	1
Bogomolova, A; Filippov, SK; Hrubý, M; Kučka, J; Pánek, J; Rabyk, M; Stěpánek, P	1
Barraja, P; Caracausi, L; Carbone, A; Cirrincione, G; Diana, P; Montalbano, A; Parrino, B; Spanò, V	1
Chagnac, A; Gafter, U; Herman, M; Korzets, A; Malachi, T; Ori, Y; Weinstein, T; Zevin, D	1
Blagden, S; de Bono, J	1
Esumi, H; Ikeda, D; Kawada, M; Kunimoto, S; Masuda, T; Ohba, S; Osono, M	1
Anway, MD; Leathers, C; Skinner, MK	1
Arnold, LL; Cohen, SM; Dominick, MA; Minnema, D; Sanderson, TP; Schilling, BE; Tannehill-Gregg, SH; Ulland, B; Voelker, R; Waites, CR	1
Cloonan, ME; DiNapoli, M; Mousa, SA	1
Autexier, C; Fakhoury, J; Nimmo, GA	1
Adelman, DC; Bible, K; Heath, EI; Lorusso, PM; Martell, RE	1
Kazuo, SY	1
Glenn, M; Gunning, PT; Hamilton, AD; Jove, R; Katt, WP; Schrock, C; Schroeck, C; Sebti, SM; Siddiquee, KA; Turkson, J; Zhang, S	1
Ohyashiki, JH; Ohyashiki, K; Tauchi, T	1
Alonso, MT; Leyland-Jones, B; O'Dwyer, PJ	1
Belt, RJ; Haas, CD; Hoogstraten, B; Joseph, U; Taylor, S	1
Kjaer, M; Nielsen, H	1
Jeljaszewicz, J; Pulverer, G; Roszkowski, K; Roszkowski, W; Szmigielski, S; Wrembel, K	1
Bruno, S; McGovren, JP; Neil, GL; Penta, J; Poster, DS	1
Kufe, DW; McGovren, JP; Schade, D; Weiss, GR	1
De Bruijn, EA; Momerency, G; Slee, PH; Van Cauwenberghe, K; Van Oosterom, AT	1
Davies, AJ; Kerbel, RS	1
Tettenborn, D	1
Bone, JM; Lambie, AT; Robson, JS	1
Kramer, KP; Norpoth, K; Rauen, HM	1

Reviews

12 review(s) available for oxazoles and Neoplasms

Article	Year
Recent Developments in Oxazole Derivatives as Anticancer Agents: Review on Synthetic Strategies, Mechanism of Action and SAR Studies. Anti-cancer agents in medicinal chemistry, 2022, Volume: 22, Issue:10 Topics: Antineoplastic Agents; Humans; Neoplasms; Oxazoles; Protein Kinases; Structure-Activity Relationship	2022
A functional scaffold in marine alkaloid: an anticancer moiety for human. Current medicinal chemistry, 2013, Volume: 20, Issue:31 Topics: Alkaloids; Animals; Antineoplastic Agents; Humans; Indoles; Neoplasms; Oxazoles; Pyridines; Pyrroles; Quinolines	2013
Addressing the employment-related needs of cancer survivors. Work (Reading, Mass.), 2013, Volume: 46, Issue:4 Topics: Adult; Aged; Data Collection; Disabled Persons; Employment; Female; Humans; Information Seeking Behavior; Male; Middle Aged; Needs Assessment; Neoplasms; Oxazoles; Pilot Projects; Pyridines; Social Support; Survivors; Workplace	2013
Overview of CDK9 as a target in cancer research. Cell cycle (Georgetown, Tex.), 2016, Volume: 15, Issue:4 Topics: Bridged Bicyclo Compounds, Heterocyclic; Cell Cycle; Cyclic N-Oxides; Cyclin-Dependent Kinase 9; Flavonoids; Humans; Indolizines; Molecular Targeted Therapy; Neoplasms; Oxazoles; Piperidines; Protein Kinase Inhibitors; Purines; Pyrazoles; Pyridinium Compounds; Roscovitine; Thiazoles; Urea	2016
Utilization of microbial iron assimilation processes for the development of new antibiotics and inspiration for the design of new anticancer agents. Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine, 2009, Volume: 22, Issue:1 Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents; Antitubercular Agents; Bacteria; Drug Delivery Systems; Drug Design; Drug Resistance, Microbial; Humans; Iron; Microbial Sensitivity Tests; Molecular Structure; Neoplasms; Oxazoles; Siderophores	2009
Carcinogenic aspects of protein phosphatase 1 and 2A inhibitors. Progress in molecular and subcellular biology, 2009, Volume: 46 Topics: Animals; Carcinogens; Disease Progression; Enzyme Inhibitors; Humans; Marine Toxins; Mice; Models, Molecular; Neoplasms; Neoplasms, Experimental; Okadaic Acid; Oxazoles; Protein Phosphatase 1; Protein Phosphatase 2; Rats; Skin Neoplasms; Stomach Neoplasms; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha	2009
Drugging cell cycle kinases in cancer therapy. Current drug targets, 2005, Volume: 6, Issue:3 Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents; Binding Sites; Cyclin-Dependent Kinases; Flavonoids; Humans; Neoplasms; Oxazoles; Piperidines; Protein Kinase Inhibitors; Purines; Roscovitine; Staurosporine; Sulfonamides; Thiazoles	2005
Harnessing telomerase in cancer therapeutics. Anti-cancer agents in medicinal chemistry, 2007, Volume: 7, Issue:4 Topics: Animals; Antineoplastic Agents; Genetic Therapy; Humans; Immunotherapy; Models, Chemical; Models, Genetic; Neoplasms; Oligonucleotides, Antisense; Oxazoles; Promoter Regions, Genetic; RNA; Telomerase	2007
[Studies on bioactive substances of microbial origin that were screened based on molecular targets]. The Japanese journal of antibiotics, 2007, Volume: 60, Issue:4 Topics: Animals; Antineoplastic Agents; Drug Screening Assays, Antitumor; Endoplasmic Reticulum Chaperone BiP; Heat-Shock Proteins; Humans; Macrolides; Molecular Chaperones; Neoplasms; Oligosaccharides; Oxazoles; Telomerase	2007
Acivicin. An antitumor antibiotic. Cancer clinical trials, 1981,Fall, Volume: 4, Issue:3 Topics: Animals; Antibiotics, Antineoplastic; Glycine; Humans; Isoxazoles; Neoplasms; Neoplasms, Experimental; Oxazoles	1981
The possible biological significance of Fc receptors on mammalian lymphocytes and tumor cells. Cell, 1974, Volume: 3, Issue:2 Topics: Animals; Antibodies, Neoplasm; Antibody Formation; Antibody-Producing Cells; Antigen-Antibody Complex; Antigens, Neoplasm; B-Lymphocytes; Binding Sites, Antibody; Cell Membrane; Cell Migration Inhibition; Cell Transformation, Neoplastic; Complement System Proteins; Guinea Pigs; Haplorhini; Immune Adherence Reaction; Immune Tolerance; Immunoglobulin Fc Fragments; Immunosuppression Therapy; Lymphocytes; Macrophages; Mice; Mitosis; Neoplasms; Oxazoles; Rats; T-Lymphocytes; Time Factors	1974
Intracellular pH. Advances in clinical chemistry, 1968, Volume: 11 Topics: Acid-Base Equilibrium; Animals; Anticonvulsants; Blood; Body Fluids; Brain Chemistry; Cell Membrane Permeability; Chemical Phenomena; Chemistry; Electrodes; Humans; Hydrogen-Ion Concentration; Kidney Tubules; Liver; Muscles; Neoplasms; Oxazoles	1968

Trials

2 trial(s) available for oxazoles and Neoplasms

Article	Year
First-in-human Phase 1 open label study of the BET inhibitor ODM-207 in patients with selected solid tumours. British journal of cancer, 2020, Volume: 123, Issue:12 Topics: Administration, Oral; Adolescent; Adult; Aged; Antineoplastic Agents; Biological Availability; Blood Platelets; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Drug Administration Schedule; Fatigue; Female; Humans; Lung Neoplasms; Lymphoma, Non-Hodgkin; Male; Maximum Tolerated Dose; Melanoma; Middle Aged; Neoplasms; Ovarian Neoplasms; Oxazoles; Prostatic Neoplasms, Castration-Resistant; Proteins; Pyridines; Quinolines; Sarcoma; Small Cell Lung Carcinoma; Young Adult	2020
A phase 1 study of SNS-032 (formerly BMS-387032), a potent inhibitor of cyclin-dependent kinases 2, 7 and 9 administered as a single oral dose and weekly infusion in patients with metastatic refractory solid tumors. Investigational new drugs, 2008, Volume: 26, Issue:1 Topics: Administration, Oral; Adult; Aged; Anemia; Angiogenesis Inhibitors; Area Under Curve; Biological Availability; CDC2-CDC28 Kinases; Dose-Response Relationship, Drug; Female; Half-Life; Humans; Infusions, Intravenous; Male; Middle Aged; Neoplasm Metastasis; Neoplasms; Neutropenia; Oxazoles; Radiotherapy, Adjuvant; Thiazoles; Time Factors; Treatment Outcome	2008

Article

Year

First-in-human Phase 1 open label study of the BET inhibitor ODM-207 in patients with selected solid tumours.

British journal of cancer, 2020, Volume: 123, Issue:12

Topics: Administration, Oral; Adolescent; Adult; Aged; Antineoplastic Agents; Biological Availability; Blood Platelets; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Drug Administration Schedule; Fatigue; Female; Humans; Lung Neoplasms; Lymphoma, Non-Hodgkin; Male; Maximum Tolerated Dose; Melanoma; Middle Aged; Neoplasms; Ovarian Neoplasms; Oxazoles; Prostatic Neoplasms, Castration-Resistant; Proteins; Pyridines; Quinolines; Sarcoma; Small Cell Lung Carcinoma; Young Adult

2020

A phase 1 study of SNS-032 (formerly BMS-387032), a potent inhibitor of cyclin-dependent kinases 2, 7 and 9 administered as a single oral dose and weekly infusion in patients with metastatic refractory solid tumors.

Investigational new drugs, 2008, Volume: 26, Issue:1

Topics: Administration, Oral; Adult; Aged; Anemia; Angiogenesis Inhibitors; Area Under Curve; Biological Availability; CDC2-CDC28 Kinases; Dose-Response Relationship, Drug; Female; Half-Life; Humans; Infusions, Intravenous; Male; Middle Aged; Neoplasm Metastasis; Neoplasms; Neutropenia; Oxazoles; Radiotherapy, Adjuvant; Thiazoles; Time Factors; Treatment Outcome

2008

Other Studies

42 other study(ies) available for oxazoles and Neoplasms

Article	Year
SLMP53-1 interacts with wild-type and mutant p53 DNA-binding domain and reactivates multiple hotspot mutations. Biochimica et biophysica acta. General subjects, 2020, Volume: 1864, Issue:1 Topics: Apoptosis; Cell Line, Tumor; Cell Proliferation; DNA-Binding Proteins; Gene Expression Regulation, Neoplastic; Humans; Isoindoles; Mutation; Neoplasms; Oxazoles; Protein Domains; Tumor Suppressor Protein p53	2020
Preclinical Activity of HER2-Selective Tyrosine Kinase Inhibitor Tucatinib as a Single Agent or in Combination with Trastuzumab or Docetaxel in Solid Tumor Models. Molecular cancer therapeutics, 2020, Volume: 19, Issue:4 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Proliferation; Docetaxel; Drug Evaluation, Preclinical; Female; Humans; Mice; Mice, Nude; Neoplasms; Oxazoles; Pyridines; Quinazolines; Receptor, ErbB-2; Trastuzumab; Tumor Cells, Cultured; Xenograft Model Antitumor Assays	2020
Anti-Cancer Activity Based on the High Docetaxel Loaded Poly(2-Oxazoline)s Micelles. International journal of nanomedicine, 2021, Volume: 16 Topics: A549 Cells; Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Survival; Docetaxel; Drug Carriers; Drug Liberation; Endocytosis; Humans; Hydrophobic and Hydrophilic Interactions; Male; Maximum Tolerated Dose; MCF-7 Cells; Mice, Inbred BALB C; Mice, Nude; Micelles; Neoplasms; Oxazoles; Particle Size; Surface-Active Agents; Tissue Distribution	2021
PEA-OXA Mitigates Oxaliplatin-Induced Painful Neuropathy through NF-κB/Nrf-2 Axis. International journal of molecular sciences, 2021, Apr-10, Volume: 22, Issue:8 Topics: Animals; Disease Models, Animal; Ganglia, Spinal; Humans; Mice; Neoplasms; NF-E2-Related Factor 2; NF-kappa B; Oxaliplatin; Oxazoles; Pain; Peripheral Nervous System Diseases; Rats; Signal Transduction	2021
Synergistic effect of a novel autophagy inhibitor and Quizartinib enhances cancer cell death. Cell death & disease, 2018, 01-26, Volume: 9, Issue:2 Topics: Apoptosis; Autophagy; Benzothiazoles; Cell Line, Tumor; Cell Proliferation; Drug Synergism; Humans; Neoplasms; Oxazoles; Phenylurea Compounds; Receptor, ErbB-2; Signal Transduction; Triazoles	2018
Anti-mitotic chemotherapeutics promote apoptosis through TL1A-activated death receptor 3 in cancer cells. Cell research, 2018, Volume: 28, Issue:5 Topics: Animals; Antimitotic Agents; Antineoplastic Agents; Apoptosis; Autocrine Communication; Caspase 8; Cell Cycle Checkpoints; Cell Line, Tumor; Ligands; M Phase Cell Cycle Checkpoints; Mice, Nude; Neoplasms; Oxazoles; Paclitaxel; Receptors, Tumor Necrosis Factor, Member 25; Recombinant Proteins; Tumor Necrosis Factor Ligand Superfamily Member 15	2018
Oxazole and thiazole analogs of sulindac for cancer prevention. Future medicinal chemistry, 2018, 04-01, Volume: 10, Issue:7 Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Cell Line, Tumor; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Drug Design; Drug Screening Assays, Antitumor; Female; Heterografts; Humans; Male; Neoplasms; Oxazoles; Proton Magnetic Resonance Spectroscopy; Spectrometry, Mass, Electrospray Ionization; Sulindac; Thiazoles	2018
Simultaneous determination of parecoxib and its main metabolites valdecoxib and hydroxylated valdecoxib in mouse plasma with a sensitive LC-MS/MS method to elucidate the decreased drug metabolism of tumor bearing mice. Journal of pharmaceutical and biomedical analysis, 2018, Sep-05, Volume: 158 Topics: Animals; Cell Line, Tumor; Chromatography, High Pressure Liquid; Cyclooxygenase 2 Inhibitors; Cytochrome P-450 Enzyme System; Drug Monitoring; Female; Humans; Isoxazoles; Mice; Mice, Inbred BALB C; Neoplasms; Oxazoles; Prodrugs; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Sulfonamides; Tandem Mass Spectrometry; Xenograft Model Antitumor Assays	2018
A Zero Cross-Talk Ratiometric Two-Photon Probe for Imaging of Acid pH in Living Cells and Tissues and Early Detection of Tumor in Mouse Model. Analytical chemistry, 2018, 08-07, Volume: 90, Issue:15 Topics: Acids; Animals; Carbazoles; Early Detection of Cancer; Fluorescent Dyes; HeLa Cells; Humans; Hydrogen-Ion Concentration; Mice; Mice, Inbred BALB C; Mice, Nude; Microscopy, Fluorescence; Neoplasms; Optical Imaging; Oxazoles; Photons	2018
Novel oxazolinoanthracyclines as tumor cell growth inhibitors-Contribution of autophagy and apoptosis in solid tumor cells death. PloS one, 2018, Volume: 13, Issue:7 Topics: Antineoplastic Agents; Apoptosis; Autophagy; Cell Line, Tumor; Daunorubicin; Doxorubicin; Growth Inhibitors; Humans; Membrane Potential, Mitochondrial; Neoplasms; Oxazoles; Reactive Oxygen Species	2018
Discover the leading compound of 4β-S-(5-fluorobenzoxazole)-4-deoxy-4'-demethylepipodophyllotoxin with millimolar-potency toxicity by modifying the molecule structure of 4'-demethylepipodophyllotoxin. European journal of medicinal chemistry, 2018, Oct-05, Volume: 158 Topics: Antineoplastic Agents; Apoptosis; Cell Line; Cell Line, Tumor; Drug Design; Halogenation; Hep G2 Cells; Humans; Models, Molecular; Neoplasms; Oxazoles; Podophyllotoxin	2018
Directed production of aurantizolicin and new members based on a YM-216391 biosynthetic system. Organic & biomolecular chemistry, 2018, 12-12, Volume: 16, Issue:48 Topics: Amino Acid Sequence; Antineoplastic Agents; Biosynthetic Pathways; Cell Line, Tumor; Cell Survival; Genes, Bacterial; Genetic Engineering; Humans; Multigene Family; Neoplasms; Oxazoles; Peptides, Cyclic; Streptomyces; Streptomyces coelicolor	2018
Synthesis and HDAC inhibitory activity of isosteric thiazoline-oxazole largazole analogs. Bioorganic & medicinal chemistry letters, 2013, Nov-01, Volume: 23, Issue:21 Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Depsipeptides; Histone Deacetylase Inhibitors; Humans; Molecular Docking Simulation; Neoplasms; Oxazoles; Thiazoles	2013
Poly(2-oxazoline) hydrogels as next generation three-dimensional cell supports. Cell adhesion & migration, 2014, Volume: 8, Issue:2 Topics: Cell Adhesion; Cell Culture Techniques; Fibroblasts; Humans; Hydrogels; Neoplasms; Oxazoles; Polyethylene Glycols	2014
Synthesis of the biologically active natural product cyclodepsipeptides apratoxin A and its analogues. Chemical & pharmaceutical bulletin, 2014, Volume: 62, Issue:8 Topics: Antineoplastic Agents; Biological Products; Depsipeptides; HeLa Cells; Humans; Neoplasms; Oxazoles; Solid-Phase Synthesis Techniques	2014
High glucose dephosphorylates serine 46 and inhibits p53 apoptotic activity. Journal of experimental & clinical cancer research : CR, 2014, Sep-27, Volume: 33 Topics: Apoptosis; Cell Line, Tumor; Cell Nucleus; Cisplatin; Doxorubicin; Drug Interactions; Glucose; HCT116 Cells; Humans; Marine Toxins; Neoplasms; Oxazoles; Phosphoprotein Phosphatases; Phosphorylation; Serine; Transcriptional Activation; Transfection; Tumor Suppressor Protein p53	2014
Molecular biology: Remove, reuse, recycle. Nature, 2014, Oct-16, Volume: 514, Issue:7522 Topics: Aging; Alzheimer Disease; Autophagy; Biomedical Research; Caloric Restriction; HIV; Humans; Longevity; Neoplasms; Oxazoles; Parkinson Disease; Phagosomes; Rilmenidine	2014
Cancer stem cell drugs target K-ras signaling in a stemness context. Oncogene, 2016, 10-06, Volume: 35, Issue:40 Topics: Calmodulin; Caveolae; Gene Expression Regulation, Neoplastic; Humans; MCF-7 Cells; Neoplasms; Neoplastic Stem Cells; Oxazoles; Proto-Oncogene Proteins p21(ras); Pyrans; ras Proteins; Sesterterpenes	2016
Onco-IP3Rs Feed Cancerous Cravings for Mitochondrial Ca(2.). Trends in biochemical sciences, 2016, Volume: 41, Issue:5 Topics: AMP-Activated Protein Kinases; Calcium; Calcium Channels; Cell Death; Cell Proliferation; Endoplasmic Reticulum; Enzyme Activation; G1 Phase Cell Cycle Checkpoints; Gene Expression; Humans; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Ion Transport; Macrocyclic Compounds; Mitochondria; Neoplasms; Organ Specificity; Oxazoles; Pyruvic Acid; RNA, Small Interfering; Tumor Cells, Cultured; Voltage-Dependent Anion Channels	2016
Preclinical efficacy of a carboxylesterase 2-activated prodrug of doxazolidine. Journal of medicinal chemistry, 2009, Dec-10, Volume: 52, Issue:23 Topics: Animals; Antineoplastic Agents; Blotting, Western; Carbamates; Carboxylesterase; Cell Line, Tumor; Cell Proliferation; Doxorubicin; Drug Evaluation, Preclinical; Female; Gene Expression Regulation, Enzymologic; Humans; Mice; Myocytes, Cardiac; Neoplasms; Oxazoles; Prodrugs; Rats; Regression Analysis	2009
An expeditious synthesis and anticancer activity of novel 4-(3'-indolyl)oxazoles. European journal of medicinal chemistry, 2010, Volume: 45, Issue:3 Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Humans; Indoles; Molecular Structure; Neoplasms; Oxazoles	2010
Doubly amphiphilic poly(2-oxazoline)s as high-capacity delivery systems for hydrophobic drugs. Biomaterials, 2010, Volume: 31, Issue:18 Topics: Animals; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Carcinoma, Lewis Lung; Cell Line, Tumor; Cell Survival; Complement Activation; Female; Humans; Hydrophobic and Hydrophilic Interactions; Mice; Mice, Inbred C57BL; Micelles; Neoplasms; Oxazoles; Paclitaxel; Polymers; Solubility	2010
Isolation, structural elucidation, and absolute stereochemistry of enigmazole A, a cytotoxic phosphomacrolide from the Papua New Guinea marine sponge Cinachyrella enigmatica. Journal of the American Chemical Society, 2010, Aug-04, Volume: 132, Issue:30 Topics: Animals; Antineoplastic Agents; Drug Screening Assays, Antitumor; Humans; Macrolides; Models, Molecular; Molecular Structure; Neoplasms; Organophosphorus Compounds; Oxazoles; Papua New Guinea; Porifera	2010
A new diketopiperazine, cyclo-(4-S-hydroxy-R-proline-R-isoleucine), from an Australian specimen of the sponge Stelletta sp. Marine drugs, 2011, Volume: 9, Issue:11 Topics: Animals; Antineoplastic Agents; Australia; Azepines; Cell Line; Cell Line, Tumor; Diketopiperazines; Humans; Neoplasms; Oxazoles; Peptides, Cyclic; Porifera	2011
The biosynthetic products of Chinese insect medicine, Aspongopus chinensis. Fitoterapia, 2012, Volume: 83, Issue:4 Topics: Animals; Biological Products; Biosynthetic Pathways; Cell Line, Tumor; Dopamine; Hemiptera; Humans; Molecular Structure; Neoplasms; Oxazoles	2012
Thermoresponsive nanoparticles based on poly(2-alkyl-2-oxazolines) and Pluronic F127. Macromolecular rapid communications, 2012, Oct-15, Volume: 33, Issue:19 Topics: Calorimetry; Iodine Radioisotopes; Isotope Labeling; Micelles; Nanoparticles; Neoplasms; Oxazoles; Poloxamer; Radionuclide Imaging; Transition Temperature	2012
Synthesis and antiproliferative activity of the ring system [1,2]oxazolo[4,5-g]indole. ChemMedChem, 2012, Volume: 7, Issue:11 Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Humans; Indoles; Neoplasms; Oxazoles; Structure-Activity Relationship	2012
DNA repair in mononuclear cells: role of serine/threonine phosphatases. The Journal of laboratory and clinical medicine, 2002, Volume: 140, Issue:4 Topics: Calcineurin; Calcineurin Inhibitors; Cyclosporine; DNA Repair; Enzyme Inhibitors; Humans; Immunosuppressive Agents; In Vitro Techniques; Kidney Transplantation; Leukocytes, Mononuclear; Marine Toxins; Neoplasms; Oxazoles; Phosphates; Phosphoprotein Phosphatases; Signal Transduction; Tacrolimus; Ultraviolet Rays	2002
Antitumor effect of kigamicin D on mouse tumor models. The Journal of antibiotics, 2006, Volume: 59, Issue:4 Topics: Animals; Antibiotics, Antineoplastic; Cell Line, Tumor; Colonic Neoplasms; Disease Models, Animal; Doxorubicin; Female; Humans; Lung Neoplasms; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Neoplasms; Neovascularization, Pathologic; Oxazoles; Pancreatic Neoplasms; Xenograft Model Antitumor Assays	2006
Endocrine disruptor vinclozolin induced epigenetic transgenerational adult-onset disease. Endocrinology, 2006, Volume: 147, Issue:12 Topics: Animals; Crosses, Genetic; Endocrine Disruptors; Epigenesis, Genetic; Female; Fetal Development; Genetic Diseases, Inborn; Humans; Male; Maternal Exposure; Neoplasms; Oxazoles; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley	2006
Rodent carcinogenicity profile of the antidiabetic dual PPAR alpha and gamma agonist muraglitazar. Toxicological sciences : an official journal of the Society of Toxicology, 2007, Volume: 98, Issue:1 Topics: Animals; Carcinogenicity Tests; Carcinogens; Dose-Response Relationship, Drug; Female; Glycine; Hypoglycemic Agents; Male; Mice; Mice, Inbred ICR; Neoplasms; Oxazoles; PPAR alpha; PPAR gamma; Rats; Rats, Sprague-Dawley; Survival Analysis; Urinalysis	2007
Efficacy of anticoagulants and platelet inhibitors in cancer-induced thrombosis. Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2007, Volume: 18, Issue:4 Topics: Alanine; Cell Line, Tumor; Drug Therapy, Combination; Enoxaparin; Heparin, Low-Molecular-Weight; Humans; Neoplasms; Oxazoles; Platelet Glycoprotein GPIIb-IIIa Complex; Thrombelastography; Thromboplastin; Thrombosis; Tinzaparin	2007
An oxazole-based small-molecule Stat3 inhibitor modulates Stat3 stability and processing and induces antitumor cell effects. ACS chemical biology, 2007, Dec-21, Volume: 2, Issue:12 Topics: Neoplasms; Oxazoles; STAT3 Transcription Factor	2007
Telomerase inhibition combined with other chemotherapeutic reagents to enhance anti-cancer effect. Methods in molecular biology (Clifton, N.J.), 2007, Volume: 405 Topics: Animals; Antineoplastic Agents; Benzamides; Drug Synergism; Humans; Imatinib Mesylate; K562 Cells; Neoplasms; Oxazoles; Piperazines; Pyrimidines; Telomerase	2007
Acivicin: a new glutamine antagonist in clinical trials. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1984, Volume: 2, Issue:9 Topics: Animals; Antibiotics, Antineoplastic; Antimetabolites; Dose-Response Relationship, Drug; Drug Evaluation; Female; Glutamine; Half-Life; Humans; Isoxazoles; Kinetics; Leukemia, Experimental; Liver Neoplasms, Experimental; Macaca mulatta; Male; Mice; Neoplasms; Oxazoles; Purines; Pyrimidines; Sarcoma, Experimental	1984
Phase I evaluation of AT-125 single dose every three weeks. Investigational new drugs, 1984, Volume: 2, Issue:3 Topics: Adult; Aged; Antibiotics, Antineoplastic; Central Nervous System; Drug Administration Schedule; Drug Evaluation; Glutamine; Humans; Isoxazoles; Middle Aged; Neoplasms; Oxazoles	1984
The analgesic effect of the GABA-agonist THIP in patients with chronic pain of malignant origin. A phase-1-2 study. British journal of clinical pharmacology, 1983, Volume: 16, Issue:5 Topics: Adult; Aged; Analgesics; Analysis of Variance; Chronic Disease; Drug Evaluation; Female; Humans; Isoxazoles; Male; Middle Aged; Neoplasms; Oxazoles; Pain	1983
Effect of whole-body hyperthermia on delayed cutaneous hypersensitivity to oxazolone in mice. Journal of clinical & laboratory immunology, 1981, Volume: 6, Issue:3 Topics: Animals; Hot Temperature; Hypersensitivity, Delayed; Hyperthermia, Induced; Immunosuppression Therapy; Lymph Nodes; Lymphocyte Activation; Male; Mice; Mice, Inbred BALB C; Neoplasms; Oxazoles; Oxazolone; Skin; T-Lymphocytes	1981
Phase I and pharmacological study of acivicin by 24-hour continuous infusion. Cancer research, 1982, Volume: 42, Issue:9 Topics: Antimetabolites; Digestive System; Drug Evaluation; Humans; Infusions, Parenteral; Isoxazoles; Kinetics; Neoplasms; Nervous System; Oxazoles	1982
The determination of cyclophosphamide and its metabolites in blood plasma as stable trifluoroacetyl derivatives by electron capture chemical ionization gas chromatography/mass spectrometry. Biological mass spectrometry, 1994, Volume: 23, Issue:3 Topics: Antineoplastic Agents; Cyclophosphamide; Gas Chromatography-Mass Spectrometry; Humans; Neoplasms; Nitrogen Mustard Compounds; Oxazoles; Oxazolidinones; Phosphoramide Mustards	1994
[The toxicology of glisoxepide, a new oral antidiabetic. Results of animal studies]. Arzneimittel-Forschung, 1974, Volume: 24, Issue:0 Topics: Abnormalities, Drug-Induced; Administration, Oral; Animals; Azepines; Blood Glucose; Body Weight; Cats; Depression, Chemical; Dogs; Drug Evaluation, Preclinical; Female; Fertility; Glucose Tolerance Test; Hypoglycemia; Hypoglycemic Agents; Injections, Intravenous; Lethal Dose 50; Mice; Neoplasms; Oxazoles; Pregnancy; Rabbits; Rats; Seizures; Sulfonylurea Compounds; Time Factors	1974
[Fate of free bis(beta-chloroethyl)-amine in blood serum]. Arzneimittel-Forschung, 1965, Volume: 15, Issue:9 Topics: Animals; Antineoplastic Agents; Azirines; Bicarbonates; Blood; Chlorides; Ethylamines; Humans; In Vitro Techniques; Neoplasms; Oxazoles; Rats	1965