Page last updated: 2024-08-21

oxazoles and Dementia Praecox

oxazoles has been researched along with Dementia Praecox in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19906 (31.58)18.7374
1990's5 (26.32)18.2507
2000's0 (0.00)29.6817
2010's7 (36.84)24.3611
2020's1 (5.26)2.80

Authors

AuthorsStudies
Brown, J; Di Cicco, G; Fletcher, J; Grayson, B; Harte, M; Iacovelli, L; Neill, JC; Ngomba, RT; Rimmer, L; Wall, MJ1
Aleksandrov, AA; Dmitrieva, ES; Gainetdinov, RR; Knyazeva, VM; Polyakova, NV; Volnova, AB1
Chaki, S; Hikichi, H; Hiyoshi, T; Iida, I; Kaku, A; Karasawa, J; Marumo, T; Tamita, T; Tomishima, Y; Urabe, H; Yasuhara, A1
Chen, B; Huang, L; Song, J; Yin, L; Zhang, W; Zhang, X1
Balu, DT; Bolshakov, VY; Conn, PJ; Coyle, JT; Jones, CK; Li, Y; Lindsley, CW; Presti, KT; Ramikie, TS; Rook, JM; Takagi, S1
Bergis, OE; Black, MD; Boulay, D; Defex, H; Desvignes, C; Featherstone, R; Griebel, G; Kongsamut, S; Kosley, R; Naimoli, V; Pichat, P; Potestio, L; Sahni, S; Sher, R; Slowinski, F; Varty, GB; Vigé, X1
Bronk, BS; Bryce, DK; Coe, JW; Cook, KK; Duplantier, AJ; Evrard, E; Hajós, M; Hoffmann, WE; Hurst, RS; Maklad, N; Mather, RJ; McLean, S; Nedza, FM; O'Donnell, CJ; O'Neill, BT; Peng, L; Qian, W; Rogers, BN; Rottas, MM; Sands, SB; Schmidt, AW; Shrikhande, AV; Spracklin, DK; Wong, DF; Zhang, A; Zhang, L1
Bradaia, A; Bruns, A; Buchy, D; Chaboz, S; Galley, G; Groebke Zbinden, K; Hoener, MC; Kilduff, TS; Metzler, V; Morairty, SR; Moreau, JL; Mory, R; Norcross, RD; Pouzet, B; Revel, FG; Risterucci, C; Tuerck, D; Wallace, TL; Wettstein, JG1
Altmann, H; Dose, M; Emrich, HM; von Zerssen, D1
Hanada, S; Hosomi, T; Isoda, K; Kasai, T; Kuno, T; Kuyama, T; Mita, T; Nakai, H; Nishino, N; Uchida, S1
Frieboes, RM; Holsboer, F; Murck, H; Steiger, A; Wiedemann, K1
Antonijevic, I; Frieboes, RM; Hinze-Selch, D; Kraus, T; Murck, H; Pollmächer, T; Steiger, A1
Gotthardt, U; Huber, MT; Krieg, JC; Schreiber, W1
Andreas, J; Benkert, O; Eissner, D; Gründer, G; Heydari, N; Müller, MJ; Nickel, O; Schlegel, S; Schlösser, R; Wetzel, H1
Benkert, O; Gründer, G; Marx-Dannigkeit, P; Müller, MJ; Müller-Siecheneder, F; Wetzel, H1
Chase, TN; Crayton, JW; Tamminga, CA1
Chase, TN; Frohman, LA; Neophytides, A; Tamminga, CA1
McDonald, A1
Sharpley, P; Small, IF; Small, JG1

Trials

5 trial(s) available for oxazoles and Dementia Praecox

ArticleYear
Therapeutic effects of GABA-ergic drugs in affective disorders. A preliminary report.
    Pharmacology, biochemistry, and behavior, 1983, Volume: 19, Issue:2

    Topics: Adolescent; Adult; Analgesics; Anticonvulsants; Bipolar Disorder; Carbamazepine; Clinical Trials as Topic; Diazepam; Double-Blind Method; Female; gamma-Aminobutyric Acid; Humans; Isoxazoles; Male; Middle Aged; Mood Disorders; Oxazoles; Oxcarbazepine; Schizophrenia; Valproic Acid

1983
Open clinical trial on the sigma ligand panamesine in patients with schizophrenia.
    Psychopharmacology, 1997, Volume: 132, Issue:1

    Topics: Acute Disease; Adolescent; Adult; Antipsychotic Agents; Brief Psychiatric Rating Scale; Female; Humans; Male; Oxazoles; Piperidines; Prolactin; Receptors, sigma; Schizophrenia; Sleep

1997
Characterization of the sigma ligand panamesine, a potential antipsychotic, by immune response in patients with schizophrenia and by sleep-EEG changes in normal controls.
    Psychopharmacology, 1999, Volume: 141, Issue:1

    Topics: Adjuvants, Immunologic; Adolescent; Adult; Antipsychotic Agents; Blood Cell Count; Double-Blind Method; Electroencephalography; Female; Humans; Locus Coeruleus; Male; Oxazoles; Piperidines; Receptors, sigma; Schizophrenia; Sleep; Tumor Necrosis Factor-alpha

1999
Efficacy and safety of the sigma receptor ligand EMD 57445 (panamesine) in patients with schizophrenia: an open clinical trial.
    Pharmacopsychiatry, 1999, Volume: 32, Issue:2

    Topics: Adult; Antipsychotic Agents; Female; Humans; Ligands; Male; Middle Aged; Oxazoles; Piperidines; Psychiatric Status Rating Scales; Receptors, sigma; Schizophrenia; Schizophrenic Psychology

1999
Antipsychotic effects and tolerability of the sigma ligand EMD 57445 (panamesine) and its metabolites in acute schizophrenia: an open clinical trial.
    Psychiatry research, 1999, Dec-27, Volume: 89, Issue:3

    Topics: Acute Disease; Adult; Aged; Antipsychotic Agents; Basal Ganglia Diseases; Biotransformation; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Oxazoles; Piperidines; Psychiatric Status Rating Scales; Receptors, sigma; Schizophrenia; Schizophrenic Psychology; Treatment Outcome

1999

Other Studies

14 other study(ies) available for oxazoles and Dementia Praecox

ArticleYear
The comparative effects of mGlu5 receptor positive allosteric modulators VU0409551 and VU0360172 on cognitive deficits and signalling in the sub-chronic PCP rat model for schizophrenia.
    Neuropharmacology, 2022, 05-01, Volume: 208

    Topics: Allosteric Regulation; Animals; Cognition; Niacinamide; Oxazoles; Phencyclidine; Proto-Oncogene Proteins c-akt; Pyridines; Rats; Receptor, Metabotropic Glutamate 5; Schizophrenia

2022
Effect of trace amine-associated receptor 1 agonist RO5263397 on sensory gating in mice.
    Neuroreport, 2019, 10-16, Volume: 30, Issue:15

    Topics: Amines; Animals; Antipsychotic Agents; Cognition; Evoked Potentials; Evoked Potentials, Auditory; Male; Mice; Mice, Inbred C57BL; Oxazoles; Receptors, G-Protein-Coupled; Schizophrenia; Schizophrenic Psychology; Sensory Gating

2019
Antipsychotic profiles of TASP0443294, a novel and orally active positive allosteric modulator of metabotropic glutamate 2 receptor.
    Journal of pharmacological sciences, 2015, Volume: 127, Issue:3

    Topics: Administration, Oral; Allosteric Regulation; Animals; Antipsychotic Agents; Cells, Cultured; Disease Models, Animal; Electroencephalography; Humans; Imidazoles; Male; Motor Activity; Oxazoles; Prefrontal Cortex; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Metabotropic Glutamate; Schizophrenia; Sleep, REM; Stimulation, Chemical

2015
Synthesis and pharmacological evaluation of piperidine (piperazine)-substituted benzoxazole derivatives as multi-target antipsychotics.
    Bioorganic & medicinal chemistry letters, 2015, Nov-15, Volume: 25, Issue:22

    Topics: Animals; Antipsychotic Agents; Ether-A-Go-Go Potassium Channels; Humans; Mice; Oxazoles; Patch-Clamp Techniques; Piperazines; Piperidines; Potassium Channel Blockers; Rats; Receptors, Dopamine D2; Schizophrenia; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT2 Receptor Agonists; Structure-Activity Relationship; Swine

2015
An mGlu5-Positive Allosteric Modulator Rescues the Neuroplasticity Deficits in a Genetic Model of NMDA Receptor Hypofunction in Schizophrenia.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2016, Volume: 41, Issue:8

    Topics: Allosteric Regulation; Animals; Disease Models, Animal; Hippocampus; Male; Mice, Inbred C57BL; Mice, Knockout; Neuronal Plasticity; Oxazoles; Proto-Oncogene Proteins c-akt; Pyridines; Racemases and Epimerases; Receptor, Metabotropic Glutamate 5; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Signal Transduction

2016
The mGluR2 positive allosteric modulator, SAR218645, improves memory and attention deficits in translational models of cognitive symptoms associated with schizophrenia.
    Scientific reports, 2016, 10-13, Volume: 6

    Topics: Allosteric Site; Amphetamines; Animals; Attention; Calcium; Cerebral Cortex; Cognition; Cognition Disorders; Cyclic AMP; Dizocilpine Maleate; Electroconvulsive Therapy; HEK293 Cells; Humans; Indans; Male; Maze Learning; Memory; Memory, Short-Term; Mice; Mice, Inbred C57BL; Mice, Transgenic; Oxazoles; Phenotype; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Schizophrenia

2016
Discovery of 4-(5-methyloxazolo[4,5-b]pyridin-2-yl)-1,4-diazabicyclo[3.2.2]nonane (CP-810,123), a novel alpha 7 nicotinic acetylcholine receptor agonist for the treatment of cognitive disorders in schizophrenia: synthesis, SAR development, and in vivo eff
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Azabicyclo Compounds; Biological Availability; Cells, Cultured; Cognition Disorders; Epithelial Cells; Female; Hippocampus; Humans; Kidney; Microsomes, Liver; Nicotinic Agonists; Nootropic Agents; Oocytes; Oxazoles; Rats; Receptors, Nicotinic; Schizophrenia; Skin; Structure-Activity Relationship; Xenopus laevis

2010
A new perspective for schizophrenia: TAAR1 agonists reveal antipsychotic- and antidepressant-like activity, improve cognition and control body weight.
    Molecular psychiatry, 2013, Volume: 18, Issue:5

    Topics: Analysis of Variance; Animals; Antipsychotic Agents; Attention; Benzodiazepines; Body Weight; Cocaine; Conditioning, Operant; Depression; Disease Models, Animal; Dopamine Uptake Inhibitors; Electroencephalography; Hallucinogens; Haloperidol; Humans; Macaca fascicularis; Magnetic Resonance Imaging; Male; Mental Recall; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microinjections; Motor Activity; Mutation; Olanzapine; Oocytes; Oxazoles; Phencyclidine; Phenethylamines; Protein Binding; Pyrrolidinones; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Reinforcement, Psychology; Schizophrenia; Swimming; Telemetry; Tritium; Xenopus

2013
[Increased 3H-muscimol binding in post-mortem brains of chronic schizophrenics].
    Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica, 1984, Volume: 86, Issue:3

    Topics: Adult; Aged; Binding Sites; Chronic Disease; Female; Frontal Lobe; Glutamate Decarboxylase; Humans; Male; Middle Aged; Muscimol; Oxazoles; Putamen; Schizophrenia

1984
Occupancy of striatal D(2)-like dopamine receptors after treatment with the sigma ligand EMD 57445, a putative atypical antipsychotic.
    Psychopharmacology, 1999, Sep-01, Volume: 146, Issue:1

    Topics: Adult; Antipsychotic Agents; Benzamides; Blood-Brain Barrier; Corpus Striatum; Female; Humans; Male; Middle Aged; Oxazoles; Piperidines; Pyrimidines; Pyrrolidines; Receptors, Dopamine D2; Receptors, sigma; Schizophrenia; Tomography, Emission-Computed, Single-Photon

1999
Improvement in tardive dyskinesia after muscimol therapy.
    Archives of general psychiatry, 1979, Volume: 36, Issue:5

    Topics: Adult; Aged; Antipsychotic Agents; Dopamine; Drug Evaluation; Dyskinesia, Drug-Induced; Extrapyramidal Tracts; Female; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Muscimol; Oxazoles; Receptors, Dopamine; Schizophrenia; Stimulation, Chemical; Synaptic Transmission

1979
Stimulation of prolactin and growth hormone secretion by muscimol, a gamma-aminobutyric acid agonist.
    The Journal of clinical endocrinology and metabolism, 1978, Volume: 47, Issue:6

    Topics: Adult; Aged; Chronic Disease; Female; gamma-Aminobutyric Acid; Growth Hormone; Humans; Huntington Disease; Kinetics; Male; Middle Aged; Muscimol; Oxazoles; Prolactin; Schizophrenia

1978
Unpleasant side effects of muscimol.
    The American journal of psychiatry, 1979, Volume: 136, Issue:10

    Topics: Humans; Muscimol; Oxazoles; Schizophrenia

1979
Influences of cylert upon memory changes with ECT.
    The American journal of psychiatry, 1968, Volume: 125, Issue:6

    Topics: Adult; Affective Symptoms; Central Nervous System Stimulants; Electroconvulsive Therapy; Electroencephalography; Female; Humans; Intelligence Tests; Magnesium; Male; Memory; Oxazoles; Pemoline; Psychiatric Status Rating Scales; Psychological Tests; Schizophrenia

1968