Page last updated: 2024-08-21

oxazoles and Colonic Neoplasms

oxazoles has been researched along with Colonic Neoplasms in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19907 (29.17)18.7374
1990's3 (12.50)18.2507
2000's7 (29.17)29.6817
2010's6 (25.00)24.3611
2020's1 (4.17)2.80

Authors

AuthorsStudies
Jiang, X; Li, C; Wu, W; Zhang, P; Zhang, X; Zhou, S1
Cai, WY; Chen, YJ; De, GJ; Hao, DL; Liu, L; Ma, H; Sui, F; Xie, R; Yang, MY; Yi, H; Zang, C; Zhao, QH1
Chu, E; Guo, Z; Hopkins, CD; Schmitz, JC; Wei, N; Wipf, P; Wu, S1
Bessa, C; Bisio, A; Fernandes, J; Gomes, C; Gomes, S; Gonçalves, J; Inga, A; Monteiro, Â; Pereira, C; Pereira, NA; Queiroz, G; Raimundo, L; Reis, F; Santos, MM; Saraiva, L; Soares, J1
Han, H; Stephens, B; Von Hoff, DD; Wang, H1
Brown, AM; Cardozo, T; Carson, BB; DasGupta, R; Ekas, LA; Evans, S; Gonsalves, FC; Katz, S; Klein, K; Nagourney, R1
Al-Abed, Y; Donia, M; Fagone, P; Maksimovic-Ivanic, D; Mangano, K; McCubrey, JA; Mijatovic, S; Miljkovic, D; Mojic, M; Nicoletti, F; Stankovic, M; Stosic-Grujicic, S; Travali, S; Zocca, MB1
Fujii, G; Komiya, M; Mutoh, M; Noma, N; Shimura, M; Takahashi, M; Tanuma, S; Yamamoto, M; Yanaka, A1
Hirakawa, K; Nagatsuka, I; Nishino, H; Ohira, M; Seki, S; Shimizu, S; Yamada, N1
Doi, K; Fukushima, S; Mitsuhashi, M; Moku, M; Morimura, K; Salim, EI; Shen, J; Wanibuchi, H; Wei, M1
Fukushima, S; Hakoi, K; Moku, M; Morimura, K; Salim, EI; Shen, J; Wanibuchi, H; Wei, M1
Asakage, M; Hori, N; Kaisaki, S; Kawai, K; Kitayama, J; Nagawa, H; Okaji, Y; Sunami, E; Takahashi, K; Tsuno, NH; Watanabe, T; Yazawa, K1
Esumi, H; Ikeda, D; Kawada, M; Kunimoto, S; Masuda, T; Ohba, S; Osono, M1
Feng, Y; Hörling, J; Hu, X; Leng, Y; Liu, X; Sydow-Bäckman, M; Yang, YS; Yu, JH; Zhao, XF; Zierath, JR1
Cripps, C; Eisenhauer, E; Fields, AL; Maroun, JA; Pater, JL; Stewart, DJ1
Bittner, G; Fischer, PH; Pamukcu, R; Willson, JK1
Crews, P; Nieto, RM; Rodríguez, J1
Hatano, K; Ishihara, S; Kitayama, J; Muto, T; Nagawa, H; Nita, ME; Osada, T; Shibata, Y; Sunami, E; Tomozawa, S; Tsuno, N; Tsuruo, T; Yano, H1
Acosta, AL; Rodríguez, AD1
Huber, KR; Roberts, J; Rosenfeld, H1
Eisenhauer, EA; Fields, AL; Maroun, JA; Walde, PL1
Huber, KR; Mayer, EP; Mitchell, DF; Roberts, J1
Adolphson, CC; Ajani, JA; Barlogie, B; Bedikian, AY; Bodey, GP; Korinek, J; Stroehlein, JR1
Aoki, T; Eble, JN; Glover, JL; Sebolt, JS; Weber, G1

Other Studies

24 other study(ies) available for oxazoles and Colonic Neoplasms

ArticleYear
Target-Amplified Drug Delivery of Polymer Micelles Bearing Staudinger Ligation.
    ACS applied materials & interfaces, 2019, Sep-11, Volume: 11, Issue:36

    Topics: Animals; Antineoplastic Agents; Cell Death; Cell Line, Tumor; Colonic Neoplasms; Doxorubicin; Drug Delivery Systems; Male; Mice, Inbred ICR; Micelles; Nanomedicine; Oxazoles; Polyesters; Polymers; Tissue Distribution

2019
pH-Responsive Artesunate Polymer Prodrugs with Enhanced Ablation Effect on Rodent Xenograft Colon Cancer.
    International journal of nanomedicine, 2020, Volume: 15

    Topics: Animals; Artesunate; Colonic Neoplasms; Drug Delivery Systems; Drug Liberation; Female; Humans; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Mice, Inbred BALB C; Micelles; Oxazoles; Polymers; Prodrugs; Xenograft Model Antitumor Assays

2020
Bis-cyclopropane analog of disorazole C1 is a microtubule-destabilizing agent active in ABCB1-overexpressing human colon cancer cells.
    Oncotarget, 2015, Dec-01, Volume: 6, Issue:38

    Topics: Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B; Blotting, Western; Cell Cycle; Cell Movement; Cell Proliferation; Colonic Neoplasms; Drug Resistance, Multiple; Fluorescent Antibody Technique; Humans; Immunoenzyme Techniques; Macrolides; Microtubules; Oxazoles; Tubulin Modulators; Tumor Cells, Cultured

2015
Reactivation of wild-type and mutant p53 by tryptophanolderived oxazoloisoindolinone SLMP53-1, a novel anticancer small-molecule.
    Oncotarget, 2016, Jan-26, Volume: 7, Issue:4

    Topics: Animals; Antineoplastic Agents; Apoptosis; Blotting, Western; Cell Movement; Cell Proliferation; Colonic Neoplasms; High-Throughput Screening Assays; Humans; Immunoenzyme Techniques; Isoindoles; Mice; Mice, Inbred BALB C; Mice, Nude; Mutation; Oxazoles; Piperidones; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Small Molecule Libraries; Tryptophan; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays

2016
Identification and characterization of a novel anticancer agent with selectivity against deleted in pancreatic cancer locus 4 (DPC4)-deficient pancreatic and colon cancer cells.
    Pancreas, 2009, Volume: 38, Issue:5

    Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; CDC2 Protein Kinase; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Colonic Neoplasms; Cyclin B; Cyclin-Dependent Kinases; Dose-Response Relationship, Drug; Flow Cytometry; Genotype; HCT116 Cells; Humans; Inhibitory Concentration 50; Molecular Structure; Oxazoles; Pancreatic Neoplasms; Phosphorylation; Smad4 Protein; Tumor Stem Cell Assay; Xanthones

2009
An RNAi-based chemical genetic screen identifies three small-molecule inhibitors of the Wnt/wingless signaling pathway.
    Proceedings of the National Academy of Sciences of the United States of America, 2011, Apr-12, Volume: 108, Issue:15

    Topics: Animals; Antineoplastic Agents; beta Catenin; Cell Line, Tumor; Colonic Neoplasms; Drosophila melanogaster; Drosophila Proteins; Drug Discovery; Drug Screening Assays, Antitumor; Genes, Reporter; High-Throughput Screening Assays; Humans; Mice; Oxazoles; RNA Interference; Small Molecule Libraries; Transcription, Genetic; Wnt Proteins; Wnt1 Protein; Xenograft Model Antitumor Assays

2011
Therapeutic potential of nitric oxide-modified drugs in colon cancer cells.
    Molecular pharmacology, 2012, Volume: 82, Issue:4

    Topics: Acetates; Animals; Antineoplastic Agents; Apoptosis; Caspases; Cell Adhesion; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Colonic Neoplasms; Drug Screening Assays, Antitumor; Humans; Male; Mice; Mice, Inbred BALB C; Neoplasm Metastasis; Neoplasm Transplantation; Nitric Oxide; Oxazoles; Saquinavir

2012
Novel compound SK-1009 suppresses interleukin-6 expression through modulation of activation of nuclear factor-kappaB pathway.
    Biological & pharmaceutical bulletin, 2012, Volume: 35, Issue:12

    Topics: Anti-Inflammatory Agents; Cell Line, Tumor; Colonic Neoplasms; Humans; I-kappa B Proteins; Inflammation; Inflammation Mediators; Interleukin-6; Isoindoles; Macrophages; NF-kappa B; Oxazoles; RNA, Messenger; Signal Transduction

2012
Inhibitory effect of a selective cyclooxygenase-2 inhibitor on liver metastasis of colon cancer.
    International journal of cancer, 2002, Aug-10, Volume: 100, Issue:5

    Topics: Animals; Benzenesulfonates; Cell Division; Colonic Neoplasms; Cyclooxygenase 2; Dinoprostone; Dose-Response Relationship, Drug; Endothelial Growth Factors; Enzyme-Linked Immunosorbent Assay; Humans; Isoenzymes; Liver Neoplasms; Lymphokines; Matrix Metalloproteinases; Membrane Proteins; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Invasiveness; Neoplasm Transplantation; Oxazoles; Platelet-Derived Growth Factor; Prostaglandin-Endoperoxide Synthases; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors

2002
Chemopreventive effect of JTE-522, a selective cyclooxygenase-2 inhibitor, on 1, 2-dimethylhydrazine-induced rat colon carcinogenesis.
    Cancer letters, 2003, Dec-08, Volume: 202, Issue:1

    Topics: 1,2-Dimethylhydrazine; Animals; Benzenesulfonates; Bromodeoxyuridine; Carcinogens; Cell Division; Colon; Colonic Neoplasms; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Disease Progression; Isoenzymes; Male; Oxazoles; Precancerous Conditions; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred F344

2003
JTE-522, a selective cyclooxygenase-2 inhibitor, inhibits induction but not growth and invasion of 1,2-dimethylhydrazine-induced tubular adenocarcinomas of colon in rats.
    International journal of cancer, 2005, Jan-20, Volume: 113, Issue:3

    Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma; Animals; Benzenesulfonates; Biomarkers, Tumor; Carcinogens; Colonic Neoplasms; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Disease Progression; Gene Expression Profiling; Isoenzymes; Male; Oligonucleotide Array Sequence Analysis; Oxazoles; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred F344

2005
Selective inhibition of cyclooxygenase-2 inhibits colon cancer cell adhesion to extracellular matrix by decreased expression of beta1 integrin.
    Cancer science, 2005, Volume: 96, Issue:2

    Topics: Benzenesulfonates; Cell Adhesion; Cell Division; Cell Movement; Colonic Neoplasms; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Down-Regulation; Extracellular Matrix; HT29 Cells; Humans; Integrin beta1; Membrane Proteins; Oxazoles; Prostaglandin-Endoperoxide Synthases; Tumor Cells, Cultured

2005
Antitumor effect of kigamicin D on mouse tumor models.
    The Journal of antibiotics, 2006, Volume: 59, Issue:4

    Topics: Animals; Antibiotics, Antineoplastic; Cell Line, Tumor; Colonic Neoplasms; Disease Models, Animal; Doxorubicin; Female; Humans; Lung Neoplasms; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Neoplasms; Neovascularization, Pathologic; Oxazoles; Pancreatic Neoplasms; Xenograft Model Antitumor Assays

2006
Effect of a novel non-thiazolidinedione peroxisome proliferator-activated receptor alpha/gamma agonist on glucose uptake.
    Diabetologia, 2007, Volume: 50, Issue:5

    Topics: 3T3 Cells; Adenocarcinoma; Animals; Biological Transport; Cell Line, Tumor; Colonic Neoplasms; Coumarins; Genes, Reporter; Glucose; Humans; Mice; Muscle, Skeletal; Oxazoles; PPAR alpha; PPAR gamma; Rosiglitazone; Thiazolidinediones

2007
Phase II study of acivicin in colorectal carcinoma: a National Cancer Institute of Canada study.
    Cancer treatment reports, 1984, Volume: 68, Issue:9

    Topics: Adenocarcinoma; Adult; Aged; Antibiotics, Antineoplastic; Central Nervous System Diseases; Colonic Neoplasms; Drug Administration Schedule; Drug Evaluation; Female; Hematologic Diseases; Humans; Infusions, Parenteral; Isoxazoles; Male; Middle Aged; Oxazoles; Rectal Neoplasms

1984
Enhancement of the sensitivity of human colon cancer cells to growth inhibition by acivicin achieved through inhibition of nucleic acid precursor salvage by dipyridamole.
    Cancer research, 1984, Volume: 44, Issue:8

    Topics: Antibiotics, Antineoplastic; Cell Cycle; Cell Line; Cell Survival; Colonic Neoplasms; Dipyridamole; Humans; Isoxazoles; Kinetics; Oxazoles; Ribonucleosides; Ribonucleotides

1984
New structures and bioactivity patterns of bengazole alkaloids from a choristid marine sponge.
    Journal of natural products, 1993, Volume: 56, Issue:12

    Topics: Alkaloids; Animals; Antineoplastic Agents; Colonic Neoplasms; Drug Screening Assays, Antitumor; Humans; Hydrolysis; Melanoma; Oxazoles; Porifera; Tumor Cells, Cultured

1993
Inhibition of haematogenous metastasis of colon cancer in mice by a selective COX-2 inhibitor, JTE-522.
    British journal of cancer, 1999, Volume: 81, Issue:8

    Topics: Animals; Benzenesulfonates; Cell Division; Colonic Neoplasms; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Disease Models, Animal; Isoenzymes; Lung Neoplasms; Matrix Metalloproteinase Inhibitors; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Oxazoles; Prostaglandin-Endoperoxide Synthases

1999
11-oxoaerothionin: a cytotoxic antitumor bromotyrosine-derived alkaloid from the Caribbean marine sponge Aplysina lacunosa.
    Journal of natural products, 1992, Volume: 55, Issue:7

    Topics: Animals; Antineoplastic Agents; Cell Survival; Colonic Neoplasms; Drug Screening Assays, Antitumor; Humans; Magnetic Resonance Spectroscopy; Molecular Conformation; Molecular Structure; Oxazoles; Porifera; Spiro Compounds

1992
Uptake of glutamine antimetabolites 6-diazo-5-oxo-L-norleucine (DON) and acivicin in sensitive and resistant tumor cell lines.
    International journal of cancer, 1988, May-15, Volume: 41, Issue:5

    Topics: Animals; Antibiotics, Antineoplastic; Antimetabolites; Azo Compounds; Biological Transport; Colonic Neoplasms; Diazooxonorleucine; Drug Resistance; Glutamine; Humans; Isoxazoles; Kinetics; Leukemia P388; Lung Neoplasms; Mice; Neoplasms, Experimental; Oxazoles; Tumor Cells, Cultured

1988
Phase II study of acivicin as a 72-hr continuous infusion in patients with untreated colorectal cancer. A National Cancer Institute of Canada Clinical Trials Group Study.
    Investigational new drugs, 1987, Volume: 5, Issue:4

    Topics: Adult; Aged; Antibiotics, Antineoplastic; Canada; Colonic Neoplasms; Drug Evaluation; Female; Humans; Infusions, Intravenous; Isoxazoles; Male; Middle Aged; Oxazoles; Rectal Neoplasms

1987
Cell cycle phase perturbations by 6-diazo-5-oxo-L-norleucine and acivicin in normal and neoplastic human cell lines.
    British journal of cancer, 1987, Volume: 55, Issue:6

    Topics: Antimetabolites; Azo Compounds; Cell Cycle; Cell Line; Colonic Neoplasms; Diazooxonorleucine; Drug Evaluation, Preclinical; Glutaminase; Glutamine; Humans; Isoxazoles; Lung Neoplasms; Neoplasms, Experimental; Oxazoles

1987
Phase II trial of acivicin in patients with advanced colorectal carcinoma.
    American journal of clinical oncology, 1986, Volume: 9, Issue:3

    Topics: Adult; Aged; Antibiotics, Antineoplastic; Colonic Neoplasms; Drug Evaluation; Female; Humans; Isoxazoles; Leukopenia; Male; Middle Aged; Nausea; Neoplasm Metastasis; Oxazoles; Rectal Neoplasms; Vomiting

1986
Inactivation by acivicin of carbamoyl-phosphate synthetase II of human colon carcinoma.
    Biochemical pharmacology, 1985, Jan-01, Volume: 34, Issue:1

    Topics: Antibiotics, Antineoplastic; Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing); Colon; Colonic Neoplasms; Glutamine; Humans; Isoxazoles; Kinetics; Ligases; Oxazoles

1985