oxazoles has been researched along with Cardiovascular Diseases in 21 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (9.52) | 18.2507 |
| 2000's | 8 (38.10) | 29.6817 |
| 2010's | 7 (33.33) | 24.3611 |
| 2020's | 4 (19.05) | 2.80 |
| Authors | Studies |
|---|---|
| Grobbee, DE; Heerspink, HJL; Koomen, JV; Lincoff, AM; Nicholls, SJ; Schrieks, IC; Schwartz, GG; Stevens, J; Svensson, A; Wedel, H; Weichert, A | 1 |
| Han, CL; Qu, CZ | 1 |
| Califf, RM; Demets, D; George, JT; Gerstein, HC; Granger, C; Green, JB; Hobbs, T; Holman, RR; Lawson, FC; Leiter, LA; McGuire, DK; McMurray, J; Pagidipati, NJ; Pfeffer, MA; Reusch, J; Riesmeyer, JS; Roe, MT; Rosenberg, Y; Sharma, A; Temple, R; Wiviott, S | 1 |
| Drosatos, K; Kalliora, C | 1 |
| Amoroso, R; Maccallini, C; Mollica, A | 1 |
| Bengus, M; Califf, R; Ditmarsch, M; Erdmann, E; Gerstein, HC; Malmberg, K; Ruilope, L; Schwartz, GG; Svensson, A; Volz, D; Wedel, H | 1 |
| Acri, JB; Appel, NM; Holmes, TH; Li, SH | 1 |
| Chognot, C; Henry, RR; Herz, M; Lincoff, AM; Mudaliar, S; Rabbia, M | 1 |
| Cavender, MA; Lincoff, AM | 1 |
| Davis, SN; Uhl, L; Younk, LM | 1 |
| Wilding, JP | 1 |
| Imaizumi, S; Miura, S; Saku, K; Uehara, Y; Yahiro, E | 1 |
| Nissen, SE; Topol, EJ; Wolski, K | 1 |
| Brophy, JM | 1 |
| Doux, JD; Lee, PY; Yun, AJ | 1 |
| Finkelstein, JB | 1 |
| Beckey, C; Parra, D; Thomas, T | 1 |
| Najman, DM | 1 |
| Doggrell, SA | 1 |
| Jacob, R; Rupp, H | 1 |
| Ducher, M; Fauvel, JP; Laville, M; Najem, R; Ryon, B | 1 |
6 review(s) available for oxazoles and Cardiovascular Diseases
| Article | Year |
|---|---|
Cardiovascular Risk and Safety Evaluation of a Dual Peroxisome Proliferator-Activated Receptor-Alpha/Gamma Agonist, Aleglitazar, in Patients With Type 2 Diabetes: A Meta-analysis.
Topics: Biomarkers; Blood Glucose; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Female; Glomerular Filtration Rate; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Incidence; Lipids; Male; Middle Aged; Oxazoles; PPAR alpha; PPAR gamma; Risk Assessment; Risk Factors; Thiophenes; Treatment Outcome; Weight Gain | 2020 |
The Glitazars Paradox: Cardiotoxicity of the Metabolically Beneficial Dual PPARα and PPARγ Activation.
Topics: Alkanesulfonates; Animals; Cardiotoxicity; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Energy Metabolism; Glycine; Humans; Hypoglycemic Agents; Oxazoles; Phenylpropionates; PPAR alpha; PPAR gamma; Risk Assessment; Risk Factors; Signal Transduction; Thiophenes | 2020 |
The Positive Regulation of eNOS Signaling by PPAR Agonists in Cardiovascular Diseases.
Topics: Animals; Cardiovascular Diseases; Glycine; Humans; Nitric Oxide Synthase Type III; Oxazoles; Peroxisome Proliferator-Activated Receptors; Rosiglitazone; Signal Transduction; Thiazolidinediones | 2017 |
Pharmacokinetics, efficacy and safety of aleglitazar for the treatment of type 2 diabetes with high cardiovascular risk.
Topics: Apolipoproteins B; Blood Pressure; Cardiovascular Diseases; Cholesterol, HDL; Cholesterol, LDL; Clinical Trials as Topic; Diabetes Mellitus, Type 2; Drug Interactions; Fibric Acids; Humans; Hypoglycemic Agents; Oxazoles; PPAR alpha; PPAR gamma; Thiazolidinediones; Thiophenes; Triglycerides | 2011 |
PPAR agonists for the treatment of cardiovascular disease in patients with diabetes.
Topics: Blood Glucose; Cardiovascular Diseases; Clinical Trials, Phase II as Topic; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Dyslipidemias; Humans; Hypoglycemic Agents; Oxazoles; Peroxisome Proliferator-Activated Receptors; PPAR alpha; PPAR gamma; Rosiglitazone; Thiazolidinediones; Thiophenes; Treatment Outcome | 2012 |
Chymase inhibitors.
Topics: Acetamides; Animals; Atrial Fibrillation; Azetidines; Benzoates; Cardiovascular Diseases; Chymases; Heart Failure; Humans; Hypertension; Mast Cells; Oxazoles; Pyrimidines; Quinazolines; Sulfonamides | 2013 |
4 trial(s) available for oxazoles and Cardiovascular Diseases
| Article | Year |
|---|---|
Exposure and response analysis of aleglitazar on cardiovascular risk markers and safety outcomes: An analysis of the AleCardio trial.
Topics: Aged; Cardiovascular Diseases; Clopidogrel; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Interactions; Female; Heart Disease Risk Factors; Humans; Male; Middle Aged; Oxazoles; PPAR alpha; PPAR gamma; Risk Factors; Thiophenes | 2020 |
Effects of the dual peroxisome proliferator-activated receptor activator aleglitazar in patients with Type 2 Diabetes mellitus or prediabetes.
Topics: Aged; Cardiovascular Diseases; Cerebrovascular Disorders; Coronary Disease; Diabetes Mellitus, Type 2; Double-Blind Method; Early Termination of Clinical Trials; Female; Glycated Hemoglobin; Humans; Hypoglycemia; Hypoglycemic Agents; Male; Middle Aged; Myalgia; Myocardial Infarction; Myositis; Oxazoles; Peripheral Arterial Disease; PPAR alpha; PPAR gamma; Prediabetic State; Stroke; Thiophenes; Treatment Outcome | 2015 |
Effect of the dual peroxisome proliferator-activated receptor-alpha/gamma agonist aleglitazar on risk of cardiovascular disease in patients with type 2 diabetes (SYNCHRONY): a phase II, randomised, dose-ranging study.
Topics: Analysis of Variance; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Double-Blind Method; Female; Follow-Up Studies; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Least-Squares Analysis; Male; Middle Aged; Oxazoles; Pioglitazone; PPAR alpha; PPAR gamma; Safety; Single-Blind Method; Thiazolidinediones; Thiophenes; Treatment Outcome | 2009 |
Effects of rilmenidine on stress-induced peak blood pressure and renal function.
Topics: Adrenergic alpha-Agonists; Adult; Blood Pressure; Cardiovascular Diseases; Cross-Over Studies; Double-Blind Method; Exercise Test; Humans; Kidney; Kidney Function Tests; Lithium; Male; Oxazoles; Placebos; Rilmenidine; Sodium; Stress, Psychological; Time Factors | 1999 |
11 other study(ies) available for oxazoles and Cardiovascular Diseases
| Article | Year |
|---|---|
Impact of Regulatory Guidance on Evaluating Cardiovascular Risk of New Glucose-Lowering Therapies to Treat Type 2 Diabetes Mellitus: Lessons Learned and Future Directions.
Topics: Cardiovascular Diseases; Diabetes Mellitus, Type 2; Drug-Related Side Effects and Adverse Reactions; Glucose; Glycated Hemoglobin; Glycine; Government Regulation; Humans; Hypoglycemic Agents; Oxazoles; Phenylbutazone; Practice Guidelines as Topic; Risk; Rosiglitazone; Tolbutamide; United States; United States Food and Drug Administration | 2020 |
Dopamine D3 Receptor Antagonist (GSK598809) Potentiates the Hypertensive Effects of Cocaine in Conscious, Freely-Moving Dogs.
Topics: Animals; Azabicyclo Compounds; Behavior, Addictive; Blood Pressure; Cardiovascular Diseases; Cocaine; Cocaine-Related Disorders; Dogs; Dopamine Antagonists; Male; Oxazoles; Receptors, Dopamine D3 | 2015 |
Therapeutic potential of aleglitazar, a new dual PPAR-α/γ agonist: implications for cardiovascular disease in patients with diabetes mellitus.
Topics: Cardiovascular Diseases; Diabetes Mellitus, Type 2; Humans; Hypoglycemic Agents; Oxazoles; PPAR alpha; PPAR gamma; Risk Factors; Thiophenes | 2010 |
Effect of muraglitazar on death and major adverse cardiovascular events in patients with type 2 diabetes mellitus.
Topics: Cardiovascular Diseases; Clinical Trials as Topic; Data Interpretation, Statistical; Diabetes Mellitus, Type 2; Drug Approval; Glycine; Humans; Hypoglycemic Agents; Oxazoles; PPAR alpha; PPAR gamma; Risk; Treatment Outcome; United States; United States Food and Drug Administration | 2005 |
Selling safety--lessons from muraglitazar.
Topics: Cardiovascular Diseases; Diabetes Mellitus, Type 2; Drug Approval; Glycine; Humans; Hypoglycemic Agents; Oxazoles; PPAR alpha; PPAR gamma; Risk; United States; United States Food and Drug Administration | 2005 |
Paradoxical inflammation revisited: muraglitazar and cardiovascular risk.
Topics: Cardiovascular Diseases; Glycine; Humans; Hypoglycemic Agents; Oxazoles; Risk | 2006 |
Drug safety system needs overhaul, experts say.
Topics: Cardiovascular Diseases; Conflict of Interest; Drug Approval; Drug-Related Side Effects and Adverse Reactions; Glycine; Heart; Humans; Journalism, Medical; Oxazoles; Peroxisome Proliferator-Activated Receptors; Publication Bias; United States; United States Food and Drug Administration | 2006 |
Adverse events related to muraglitazar use in diabetes.
Topics: Cardiovascular Diseases; Diabetes Mellitus, Type 2; Drug Interactions; Glycine; Humans; Hypoglycemic Agents; Oxazoles; Pioglitazone; PPAR alpha; PPAR gamma; Thiazolidinediones | 2006 |
Adverse events related to muraglitazar use in diabetes.
Topics: Cardiovascular Diseases; Diabetes Mellitus, Type 2; Drug Interactions; Glycine; Humans; Hypoglycemic Agents; Hypolipidemic Agents; Oxazoles; PPAR alpha; PPAR gamma | 2006 |
Muraglitazar: beneficial or detrimental in the treatment of Type 2 diabetes?
Topics: Adolescent; Adult; Aged; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Glycine; Humans; Hypoglycemic Agents; Middle Aged; Oxazoles; Randomized Controlled Trials as Topic; Research Design; Weight Gain | 2006 |
Excess catecholamines and the metabolic syndrome: should central imidazoline receptors be a therapeutic target?
Topics: Animals; Antihypertensive Agents; Cardiovascular Diseases; Catecholamines; Energy Intake; Energy Metabolism; Humans; Imidazoles; Imidazoline Receptors; Medulla Oblongata; Models, Biological; Neurons; Obesity; Oxazoles; Receptors, Drug; Rilmenidine; Social Conditions; Stress, Psychological; Sympathetic Nervous System | 1995 |