oxazoles has been researched along with B-Cell Chronic Lymphocytic Leukemia in 5 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Arkin, MR; Conroy, A; Fox, JA; Hawtin, RE; Hoch, U; Stockett, DE; Walker, D | 1 |
| Chen, R; Chubb, S; Fox, JA; Gandhi, V; Hawtin, RE; Keating, MJ; Plunkett, W; Wierda, WG | 1 |
| Badros, AZ; Chen, R; Chen, T; Coutre, S; Fox, JA; Harvey, RD; Hoch, U; Kegley, P; Mahadocon, K; Plunkett, W; Popplewell, L; Siegel, D; Sinha, R; Tong, WG; Wierda, WG | 1 |
| Bantscheff, M; Drewes, G; Eberhard, D; Frenzel, L; Ghidelli, S; Kruse, U; Maier, SK; Pallasch, CP; Wendtner, CM; Werner, T | 1 |
| Chen, R; Chen, Y; Guo, L; Jiang, Y; Plunkett, W; Wierda, WG | 1 |
2 trial(s) available for oxazoles and B-Cell Chronic Lymphocytic Leukemia
| Article | Year |
|---|---|
SNS-032 is a potent and selective CDK 2, 7 and 9 inhibitor that drives target modulation in patient samples.
Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cyclin-Dependent Kinases; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Multiple Myeloma; Oxazoles; Protein Kinase Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; Thiazoles | 2009 |
Phase I and pharmacologic study of SNS-032, a potent and selective Cdk2, 7, and 9 inhibitor, in patients with advanced chronic lymphocytic leukemia and multiple myeloma.
Topics: Aged; Aged, 80 and over; Biomarkers, Tumor; Cohort Studies; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase 9; Cyclin-Dependent Kinase-Activating Kinase; Cyclin-Dependent Kinases; Dose-Response Relationship, Drug; Female; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Maximum Tolerated Dose; Middle Aged; Multiple Myeloma; Oxazoles; Survival Rate; Thiazoles; Tissue Distribution; Treatment Outcome | 2010 |
3 other study(ies) available for oxazoles and B-Cell Chronic Lymphocytic Leukemia
| Article | Year |
|---|---|
Mechanism of action of SNS-032, a novel cyclin-dependent kinase inhibitor, in chronic lymphocytic leukemia.
Topics: Adult; Aged; Aged, 80 and over; Apoptosis; Caspases; Cyclin-Dependent Kinases; Female; Flavonoids; Humans; Immunoblotting; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphocytes; Male; Membrane Potential, Mitochondrial; Middle Aged; Myeloid Cell Leukemia Sequence 1 Protein; Oxazoles; Phosphorylation; Piperidines; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-bcl-2; Purines; RNA Polymerase II; RNA, Neoplasm; Roscovitine; Thiazoles; Transcription, Genetic; X-Linked Inhibitor of Apoptosis Protein | 2009 |
Chemoproteomics-based kinome profiling and target deconvolution of clinical multi-kinase inhibitors in primary chronic lymphocytic leukemia cells.
Topics: Apoptosis; Flavonoids; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Oxazoles; Piperidines; Positive Transcriptional Elongation Factor B; Protein Kinase Inhibitors; Proteomics; Thiazoles | 2011 |
Homoharringtonine reduced Mcl-1 expression and induced apoptosis in chronic lymphocytic leukemia.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Cell Proliferation; Drug Synergism; Drug Therapy, Combination; Harringtonines; Homoharringtonine; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphocytes; Middle Aged; Mitochondrial Membranes; Myeloid Cell Leukemia Sequence 1 Protein; Oxazoles; Proto-Oncogene Proteins c-bcl-2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stromal Cells; Thiazoles; Tumor Cells, Cultured | 2011 |