Page last updated: 2024-08-21

oxazoles and Akinetic-Rigid Variant of Huntington Disease

oxazoles has been researched along with Akinetic-Rigid Variant of Huntington Disease in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19907 (58.33)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (41.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barker, RA; Green-Thompson, ZW; Griffin, J; Jones, PS; Lazic, SE; Mason, SL; Pugh, PJ; Rowe, JB; Rubinsztein, DC; Underwood, BR1
Alves-Silva, J; Carvalho, TG; Conn, PJ; de Souza, JM; Doria, JG; Ferreira-Vieira, TH; Maciel, EMA; Olmo, IG; Ribeiro, FM; Santos, JT; Silva, FR; Silva, NC; Xavier, CQS1
Lin, F; Qin, ZH1
Acevedo-Arozena, A; Brown, SD; Corrochano, S; Menzies, FM; Renna, M; Rose, C; Rubinsztein, DC; Sadiq, O1
Eckenhoff, MF; Liang, G; Wang, Q; Wang, S; Wei, H; Yang, H1
Chase, TN; Denaro, A; Foster, NL; Hare, TA; Tamminga, CA1
Chase, TN; Denaro, A; Durso, R; Ruggeri, S; Tamminga, CA1
Cross, AJ; Waddington, JL1
Goetz, IE; Hamel, E; Roberts, E1
Charlton, M; Goldblatt, D; Joynt, RJ; Shoulson, I2
Chase, TN; Frohman, LA; Neophytides, A; Tamminga, CA1

Reviews

1 review(s) available for oxazoles and Akinetic-Rigid Variant of Huntington Disease

ArticleYear
Degradation of misfolded proteins by autophagy: is it a strategy for Huntington's disease treatment?
    Journal of Huntington's disease, 2013, Volume: 2, Issue:2

    Topics: Autophagy; Carbamazepine; Humans; Huntingtin Protein; Huntington Disease; Lithium; Mutant Proteins; Nerve Tissue Proteins; Oxazoles; Peptides; Rilmenidine; Sirolimus; Trehalose; Trinucleotide Repeat Expansion; Valproic Acid

2013

Trials

3 trial(s) available for oxazoles and Akinetic-Rigid Variant of Huntington Disease

ArticleYear
THIP treatment of Huntington's disease.
    Neurology, 1983, Volume: 33, Issue:5

    Topics: Adult; Clinical Trials as Topic; Disability Evaluation; Double-Blind Method; Female; Homovanillic Acid; Humans; Huntington Disease; Isoxazoles; Male; Middle Aged; Oxazoles

1983
Huntington's disease: treatment with muscimol, a GABA-mimetic drug.
    Transactions of the American Neurological Association, 1977, Volume: 102

    Topics: Amanita; Betaine; Clinical Trials as Topic; Double-Blind Method; Humans; Huntington Disease; Isoxazoles; Oxazoles

1977
Huntington's disease: treatment with muscimol, a GABA-mimetic drug.
    Annals of neurology, 1978, Volume: 4, Issue:3

    Topics: Activities of Daily Living; Adolescent; Adult; Clinical Trials as Topic; Cognition; Double-Blind Method; Female; gamma-Aminobutyric Acid; Humans; Huntington Disease; Male; Middle Aged; Muscimol; Oxazoles; Placebos

1978

Other Studies

8 other study(ies) available for oxazoles and Akinetic-Rigid Variant of Huntington Disease

ArticleYear
An open-label study to assess the feasibility and tolerability of rilmenidine for the treatment of Huntington's disease.
    Journal of neurology, 2017, Volume: 264, Issue:12

    Topics: Adolescent; Adrenergic alpha-Agonists; Adult; Aged; Brain; Female; Humans; Huntington Disease; Longitudinal Studies; Magnetic Resonance Imaging; Male; Metabolomics; Middle Aged; Neuropsychological Tests; Oxazoles; Retrospective Studies; Rilmenidine; Time Factors; Treatment Outcome; Young Adult

2017
The mGluR5 positive allosteric modulator VU0409551 improves synaptic plasticity and memory of a mouse model of Huntington's disease.
    Journal of neurochemistry, 2018, Volume: 147, Issue:2

    Topics: Animals; Conditioning, Classical; Dendritic Spines; Gene Expression Regulation; Huntington Disease; Memory Disorders; Mice; Mice, Inbred C57BL; Motor Activity; Neuronal Plasticity; Oxazoles; Pyridines; Receptor, Metabotropic Glutamate 5; Recognition, Psychology; Signal Transduction; Synapses

2018
Rilmenidine attenuates toxicity of polyglutamine expansions in a mouse model of Huntington's disease.
    Human molecular genetics, 2010, Jun-01, Volume: 19, Issue:11

    Topics: Animals; Autophagy; Cells, Cultured; Huntingtin Protein; Huntington Disease; Mice; Mice, Transgenic; Nerve Tissue Proteins; Neurons; Nuclear Proteins; Oxazoles; Peptides; Rilmenidine; Rotarod Performance Test

2010
The common inhaled anesthetic isoflurane increases aggregation of huntingtin and alters calcium homeostasis in a cell model of Huntington's disease.
    Toxicology and applied pharmacology, 2011, Feb-01, Volume: 250, Issue:3

    Topics: Anesthetics, Inhalation; Animals; Calcium; Cell Survival; Cells, Cultured; Corpus Striatum; Desflurane; Endoplasmic Reticulum; Gene Knock-In Techniques; Homeostasis; Huntingtin Protein; Huntington Disease; Isoflurane; Macrocyclic Compounds; Methyl Ethers; Mice; Nerve Tissue Proteins; Neurons; Nuclear Proteins; Oxazoles; Sevoflurane

2011
Plasma growth hormone and prolactin response to dopaminergic GABAmimetic and cholinergic stimulation in Huntington's disease.
    Neurology, 1983, Volume: 33, Issue:9

    Topics: Adult; Apomorphine; Arecoline; Dopamine; Female; gamma-Aminobutyric Acid; Growth Hormone; Humans; Huntington Disease; Male; Muscimol; Oxazoles; Prolactin

1983
Therapeutic failure of GABA agonist treatment in Huntington's disease.
    Neurology, 1984, Volume: 34, Issue:5

    Topics: gamma-Aminobutyric Acid; Humans; Huntington Disease; Isoxazoles; Oxazoles

1984
Glutamic acid decarboxylase and gamma-aminobutyric acid in Huntington's disease fibroblasts and other cultured cells, determined by a [3H]muscimol radioreceptor assay.
    Journal of neurochemistry, 1981, Volume: 37, Issue:4

    Topics: Carboxy-Lyases; Cells, Cultured; Fibroblasts; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Humans; Huntington Disease; Kinetics; Muscimol; Oxazoles; Radioligand Assay; Receptors, Cell Surface; Receptors, GABA-A; Skin

1981
Stimulation of prolactin and growth hormone secretion by muscimol, a gamma-aminobutyric acid agonist.
    The Journal of clinical endocrinology and metabolism, 1978, Volume: 47, Issue:6

    Topics: Adult; Aged; Chronic Disease; Female; gamma-Aminobutyric Acid; Growth Hormone; Humans; Huntington Disease; Kinetics; Male; Middle Aged; Muscimol; Oxazoles; Prolactin; Schizophrenia

1978