oxazoles has been researched along with Ache in 30 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (23.33) | 18.7374 |
| 1990's | 6 (20.00) | 18.2507 |
| 2000's | 9 (30.00) | 29.6817 |
| 2010's | 6 (20.00) | 24.3611 |
| 2020's | 2 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Kumar, G; Singh, NP | 1 |
| Ardizzone, A; Campolo, M; Casili, G; Cuzzocrea, S; Esposito, E; Filippone, A; Lanza, M; Mare, M; Memeo, L; Paterniti, I; Puglisi, C; Scuderi, SA | 1 |
| Cook, J; Golani, LK; Li, G; Moerke, MJ; Negus, SS | 1 |
| Cornet, M; De Ron, P; Dedoncker, P; Delaunois, A; Depelchin, BO; Guyaux, M; Hanon, E; Jnoff, E; Rosseels, ML | 1 |
| Das, AF; De Anda, C; Powers, JH; Prokocimer, P | 1 |
| Arnold, LA; Cerne, R; Cook, JM; Cramer, JW; Ernst, M; Jambrina, E; Jones, TM; Krambis, MJ; Li, G; Methuku, KR; Poe, MM; Rehman, S; Schkeryantz, JM; Stafford, DC; Teske, KA; Verma, AR; Witkin, JM | 1 |
| Chapman, V; Kendall, DA; Sagar, DR | 1 |
| Dolezal, T; Krsiak, M; Soukupová, M | 2 |
| Chen, TH; Hsieh, LL; Lee, LH; Liou, HH; Yen, AM | 1 |
| Ji, G; Li, Z; Neugebauer, V | 1 |
| Baeyens, JM; Cendán, CM; Del Pozo, E; Moncada, A | 1 |
| METRICK, S; RENTZ, L | 1 |
| Gulcan, HO; Kupeli, E; Sahin, MF; Unlu, S; Yesilada, E | 1 |
| MARINACCE, P; MERCIER, J | 1 |
| Fujita, R; Mizota, K; Uchida, H; Ueda, H; Yoshida, A | 1 |
| Khansefid, N; Ladgevardi, MA; Sabetkasaie, M | 1 |
| Brandt, MR; Cummons, TA; Harris, HA; Leventhal, L; Piesla, MJ; Rogers, KE | 1 |
| Apodaca, R; Breitenbucher, JG; Brown, S; Chang, L; Chaplan, SR; Epperson, M; Pippel, D; Scott, B; Seierstad, M; Timmons, A; Webb, M | 1 |
| Kjaer, M; Nielsen, H | 1 |
| Følsgård, S; Jacobsen, E; Kehlet, H; Lindeburg, T; Sillesen, H | 1 |
| Fernández, A; Fuentes, J; Garcia Fernández, JM; Ortiz, MC; Pradera, MA; Sánchez-Carrasco, JM; Serrano, JS; Serrano, MI | 1 |
| Crain, GM; Gelber, DA; Jung, S; Markwell, SJ; Pfeifer, MA; Ross, DR; Schrage, JP; Schumer, MP | 1 |
| Cesare, P; McNaughton, P | 1 |
| Chen, JG; Cheng, G; Randić, M; Sandkühler, J | 1 |
| Goadsby, PJ; Hoskin, KL | 1 |
| Bizot-Espiard, JG; Caignard, DH; Guillaumet, G; Pfeiffer, B; Renard, P; Savelon, L; Viaud, MC | 1 |
| Dent, RW; Ervin, DK | 1 |
| Enna, SJ; Zorn, SH | 1 |
| Drower, EJ; Hammond, DL | 1 |
4 trial(s) available for oxazoles and Ache
| Article | Year |
|---|---|
Clinician-reported lesion measurements in skin infection trials: Definitions, reliability, and association with patient-reported pain.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Double-Blind Method; Female; Humans; Male; Middle Aged; Organophosphates; Oxazoles; Pain; Reproducibility of Results; Research Design; Skin Diseases, Bacterial; Wounds and Injuries; Young Adult | 2016 |
Effect of acupressure and trigger points in treating headache: a randomized controlled trial.
Topics: Acupressure; Acupuncture Points; Adult; Aged; Aged, 80 and over; Female; Headache Disorders; Humans; Male; Middle Aged; Muscle Relaxation; Neuromuscular Agents; Oxazoles; Pain; Pain Management; Pain Measurement; Quality of Life; Relaxation Therapy; Taiwan; Treatment Outcome; Young Adult | 2010 |
A highly successful and novel model for treatment of chronic painful diabetic peripheral neuropathy.
Topics: Analgesics; Capsaicin; Diabetic Neuropathies; Exercise Therapy; Female; Glycated Hemoglobin; Humans; Imipramine; Male; Mexiletine; Middle Aged; Models, Neurological; Muscles; Oxazoles; Oxazolidinones; Pain; Pain Management; Pain Measurement; Piroxicam | 1993 |
A study of metaxalone (Skelaxin) vs. placebo in acute musculoskeletal disorders: a cooperative study.
Topics: Anthropometry; Clinical Trials as Topic; Drug Evaluation; Humans; Inflammation; Muscular Diseases; Oxazoles; Oxazolidinones; Pain; Placebos; Spasm; Wounds and Injuries | 1975 |
26 other study(ies) available for oxazoles and Ache
| Article | Year |
|---|---|
Synthesis, anti-inflammatory and analgesic evaluation of thiazole/oxazole substituted benzothiazole derivatives.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Antioxidants; Benzothiazoles; Edema; Mice; Molecular Conformation; Oxazoles; Pain; Rats; Structure-Activity Relationship; Thiazoles | 2021 |
PEA-OXA Mitigates Oxaliplatin-Induced Painful Neuropathy through NF-κB/Nrf-2 Axis.
Topics: Animals; Disease Models, Animal; Ganglia, Spinal; Humans; Mice; Neoplasms; NF-E2-Related Factor 2; NF-kappa B; Oxaliplatin; Oxazoles; Pain; Peripheral Nervous System Diseases; Rats; Signal Transduction | 2021 |
Effects of the α2/α3-subtype-selective GABAA receptor positive allosteric modulator KRM-II-81 on pain-depressed behavior in rats: comparison with ketorolac and diazepam.
Topics: Analgesics; Animals; Behavior, Animal; Conditioning, Operant; Diazepam; Electric Stimulation; Ketorolac; Male; Oxazoles; Pain; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Self Stimulation | 2019 |
Advantageous safety profile of a dual selective alpha(2C) agonist/alpha(2A) antagonist antinociceptive agent.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Analgesics; Animals; Clonidine; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Male; Mice; Oxazoles; Pain; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley | 2014 |
Synthesis and Characterization of a Novel γ-Aminobutyric Acid Type A (GABA
Topics: Animals; Anti-Anxiety Agents; Anxiety; Benzodiazepines; Dose-Response Relationship, Drug; Epilepsy; GABA-A Receptor Antagonists; HEK293 Cells; Humans; Imidazoles; Ligands; Male; Mice; Mice, Inbred Strains; Molecular Structure; Oxazoles; Pain; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Structure-Activity Relationship | 2016 |
Inhibition of fatty acid amide hydrolase produces PPAR-alpha-mediated analgesia in a rat model of inflammatory pain.
Topics: Amidohydrolases; Analgesia; Animals; Benzamides; Carbamates; Carrageenan; Disease Models, Animal; Inflammation; Oxazoles; Pain; Piperidines; PPAR gamma; Pyrazoles; Rats; Receptor, Cannabinoid, CB1; Tyrosine | 2008 |
The synergistic interaction between rilmenidine and paracetamol in the writhing test in mice.
Topics: Acetaminophen; Animals; Dose-Response Relationship, Drug; Drug Interactions; Drug Synergism; Drug Therapy, Combination; Male; Mice; Oxazoles; Pain; Pain Measurement; Rilmenidine; Rotarod Performance Test | 2009 |
Synergistic interaction between rilmenidine and ibuprofen in the writhing test in mice.
Topics: Acetic Acid; Adrenergic alpha-Agonists; Analgesics, Non-Narcotic; Analysis of Variance; Animals; Dose-Response Relationship, Drug; Drug Synergism; Ibuprofen; Male; Mice; Motor Activity; Oxazoles; Pain; Pain Measurement; Rilmenidine; Rotarod Performance Test | 2009 |
Mitochondrial reactive oxygen species are activated by mGluR5 through IP3 and activate ERK and PKA to increase excitability of amygdala neurons and pain behavior.
Topics: Amygdala; Analysis of Variance; Animals; Antioxidants; Benzoates; Cyclic AMP-Dependent Protein Kinases; Cyclic N-Oxides; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Extracellular Signal-Regulated MAP Kinases; Glycine; Inositol 1,4,5-Trisphosphate; Macrocyclic Compounds; Mitochondria; Neurons; NG-Nitroarginine Methyl Ester; Oxazoles; Pain; Pain Measurement; Pain Perception; Patch-Clamp Techniques; Pyridines; Reactive Oxygen Species; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Signal Transduction; Spin Labels; Superoxides; Thiazoles; Vocalization, Animal | 2011 |
Effects of serine/threonine protein phosphatase inhibitors on morphine-induced antinociception in the tail flick test in mice.
Topics: Analgesics, Opioid; Animals; Binding, Competitive; Cantharidin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Injections, Intraventricular; Marine Toxins; Mice; Morphine; Naloxone; Nociceptors; Okadaic Acid; Oxazoles; Pain; Pain Measurement; Phosphoprotein Phosphatases; Prosencephalon; Synaptosomes; Tritium | 2003 |
MEPHENOXALONE AS A PSYCHOTHERAPEUTIC AGENT IN CHILDREN WITH CEREBRAL DYSRHYTHMIAS: A PRELIMINARY REPORT.
Topics: Abdomen; Adolescent; Aggression; Child; Child Behavior Disorders; Drug Therapy; Electroencephalography; Epilepsy; Epilepsy, Temporal Lobe; Headache; Humans; Learning Disabilities; Nausea; Oxazoles; Pain; Temporal Lobe; Tranquilizing Agents; Vertigo; Vomiting | 1965 |
4-(5-chloro-2(3H)-benzoxazolon-3-yl) butanoic acid derivatives: synthesis, antinociceptive and anti-inflammatory properties.
Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Butyrates; Disease Models, Animal; Edema; Magnetic Resonance Spectroscopy; Male; Mice; Molecular Structure; Oxazoles; Pain; Structure-Activity Relationship | 2003 |
[Experimental analgesia action of some derivatives of oxazolidine-dione].
Topics: Analgesia; Oxazoles; Pain; Pain Management | 1952 |
Novel type of Gq/11 protein-coupled neurosteroid receptor sensitive to endocrine disrupting chemicals in mast cell line (RBL-2H3).
Topics: Animals; Behavior, Animal; beta-N-Acetylhexosaminidases; Binding, Competitive; Cattle; Cell Line, Tumor; Cell Membrane; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dose-Response Relationship, Drug; Estradiol; Estrenes; Fluorescein-5-isothiocyanate; GTP-Binding Protein alpha Subunits, Gi-Go; Leukemia, Basophilic, Acute; Macrocyclic Compounds; Male; Mast Cells; Mice; Nociceptors; Oligonucleotides, Antisense; Oxazoles; Pain; Pertussis Toxin; Phenols; Phosphodiesterase Inhibitors; Pregnenolone; Pyrrolidinones; Receptors, Steroid; Serum Albumin, Bovine; Type C Phospholipases | 2005 |
Possible role of NMDA receptors in antinociception induced by rilmenidine in mice in the formalin test.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analgesics; Animals; Benzofurans; Binding Sites; Binding, Competitive; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Synergism; Excitatory Amino Acid Antagonists; Imidazoles; Imidazoline Receptors; Male; Mice; Nervous System; Neurons, Afferent; Nociceptors; Oxazoles; Pain; Pain Measurement; Receptors, Drug; Receptors, N-Methyl-D-Aspartate; Rilmenidine; Yohimbine | 2007 |
An estrogen receptor-beta agonist is active in models of inflammatory and chemical-induced pain.
Topics: Animals; Dose-Response Relationship, Drug; Estradiol; Estrogen Receptor beta; Fulvestrant; Hot Temperature; Hyperalgesia; Inflammation; Male; Oxazoles; Pain; Rats; Rats, Sprague-Dawley | 2006 |
Novel ketooxazole based inhibitors of fatty acid amide hydrolase (FAAH).
Topics: Amidohydrolases; Animals; Binding Sites; Humans; Oxazoles; Pain; Pain Measurement; Pyridines; Rats; Spinal Nerves; Structure-Activity Relationship | 2008 |
The analgesic effect of the GABA-agonist THIP in patients with chronic pain of malignant origin. A phase-1-2 study.
Topics: Adult; Aged; Analgesics; Analysis of Variance; Chronic Disease; Drug Evaluation; Female; Humans; Isoxazoles; Male; Middle Aged; Neoplasms; Oxazoles; Pain | 1983 |
Analgesic, respiratory and endocrine responses in normal man to THIP, a GABA-agonist.
Topics: Adult; Analgesics; Dental Pulp Test; Double-Blind Method; Hormones; Humans; Hydrocortisone; Isoxazoles; Male; Oxazoles; Pain; Prolactin; Random Allocation; Respiration; Sensory Thresholds | 1983 |
Synthesis and analgesic activity of 2-amino-5-tert-butyl-2-oxazoline.
Topics: Acetates; Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Dose-Response Relationship, Drug; Male; Methimazole; Mice; Morphine; Motor Activity; Naloxone; Oxazoles; Pain; Pain Measurement; Postural Balance; Rats; Rats, Wistar | 1995 |
A novel heat-activated current in nociceptive neurons and its sensitization by bradykinin.
Topics: Animals; Animals, Newborn; Bradykinin; Cells, Cultured; Enzyme Activation; Enzyme Inhibitors; Ganglia, Spinal; Hot Temperature; Kinetics; Marine Toxins; Membrane Potentials; Neurons; Neurons, Afferent; Nociceptors; Oxazoles; Pain; Protein Kinase C; Protein Tyrosine Phosphatases; Rats; Rats, Wistar; Staurosporine; Tetradecanoylphorbol Acetate; Time Factors | 1996 |
Low-frequency stimulation of afferent Adelta-fibers induces long-term depression at primary afferent synapses with substantia gelatinosa neurons in the rat.
Topics: 2-Amino-5-phosphonovalerate; Animals; Calcium; Chelating Agents; Egtazic Acid; Electric Stimulation; Electrophysiology; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Female; Long-Term Potentiation; Male; Marine Toxins; Nerve Fibers; Neurons, Afferent; Oxazoles; Pain; Phosphoric Monoester Hydrolases; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Substantia Gelatinosa; Synaptic Transmission | 1997 |
Comparison of more and less lipophilic serotonin (5HT1B/1D) agonists in a model of trigeminovascular nociception in cat.
Topics: Animals; Cats; Cerebrovascular Circulation; Cranial Sinuses; Electric Stimulation; Gene Expression Regulation; Genes, fos; Migraine Disorders; Neurons, Afferent; Nociceptors; Oxazoles; Oxazolidinones; Pain; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Serotonin Receptor Agonists; Sumatriptan; Synaptic Transmission; Trigeminal Caudal Nucleus; Trigeminal Nerve; Trigeminal Nucleus, Spinal; Tryptamines; Vasoconstrictor Agents | 1998 |
6-aminoalkyloxazolo[4,5-b]pyridin-2(3H)-ones: synthesis and evaluation of antinoceptive activity.
Topics: Analgesics; Animals; Arachidonate 5-Lipoxygenase; Brain; Calcimycin; Cell Membrane; Cyclooxygenase Inhibitors; Drug Design; Granulocytes; Guinea Pigs; Lipoxygenase Inhibitors; Male; Mice; Molecular Structure; Oxazoles; Pain; Prostaglandin-Endoperoxide Synthases; Pyridones; Rabbits; Rats; Rats, Wistar; Receptors, Cell Surface; Structure-Activity Relationship | 1998 |
The GABA agonist THIP, attenuates antinociception in the mouse by modifying central cholinergic transmission.
Topics: Afferent Pathways; Analgesics; Animals; Central Nervous System; Cholinergic Fibers; GABA Antagonists; Isoxazoles; Male; Mice; Oxazoles; Pain; Physostigmine; Synaptic Transmission | 1987 |
GABAergic modulation of nociceptive threshold: effects of THIP and bicuculline microinjected in the ventral medulla of the rat.
Topics: Animals; Bicuculline; gamma-Aminobutyric Acid; Isoxazoles; Male; Medulla Oblongata; Microinjections; Oxazoles; Pain; Raphe Nuclei; Rats; Rats, Inbred Strains; Reaction Time; Sensory Thresholds | 1988 |