Page last updated: 2024-11-02

oxazepam and Uremia

oxazepam has been researched along with Uremia in 2 studies

Oxazepam: A benzodiazepine used in the treatment of anxiety, alcohol withdrawal, and insomnia.
oxazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a hydroxy group at position 3 and phenyl group at position 5.

Uremia: A clinical syndrome associated with the retention of renal waste products or uremic toxins in the blood. It is usually the result of RENAL INSUFFICIENCY. Most uremic toxins are end products of protein or nitrogen CATABOLISM, such as UREA or CREATININE. Severe uremia can lead to multiple organ dysfunctions with a constellation of symptoms.

Research Excerpts

ExcerptRelevanceReference
"Oxazepam has the shortest half life of the benzodiazepines and does not form any active metabolites."1.26The pharmacokinetic profile of oxazepam. ( Alván, G; Odar-Cederlöf, I, 1978)
" During multiple dosing the accumulation of conjugates was even more pronounced, with plasma concentrations amounting to 14-61 times those of oxazepam."1.26Oxazepam disposition in uremic patients. ( Alván, G; Odar-Cederlöf, I; Sjöqvist, F; Vessman, J, 1977)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19902 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Alván, G2
Odar-Cederlöf, I2
Vessman, J1
Sjöqvist, F1

Other Studies

2 other studies available for oxazepam and Uremia

ArticleYear
The pharmacokinetic profile of oxazepam.
    Acta psychiatrica Scandinavica. Supplementum, 1978, Issue:274

    Topics: Administration, Oral; Animals; Biological Availability; Dogs; Half-Life; Humans; Infusions, Parenter

1978
Oxazepam disposition in uremic patients.
    Acta pharmacologica et toxicologica, 1977, Volume: 40 Suppl 1, Issue:1

    Topics: Administration, Oral; Half-Life; Humans; Oxazepam; Uremia

1977
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