oxazepam and Uremia
oxazepam has been researched along with Uremia in 2 studies
Oxazepam: A benzodiazepine used in the treatment of anxiety, alcohol withdrawal, and insomnia.
oxazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a hydroxy group at position 3 and phenyl group at position 5.
Uremia: A clinical syndrome associated with the retention of renal waste products or uremic toxins in the blood. It is usually the result of RENAL INSUFFICIENCY. Most uremic toxins are end products of protein or nitrogen CATABOLISM, such as UREA or CREATININE. Severe uremia can lead to multiple organ dysfunctions with a constellation of symptoms.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "Oxazepam has the shortest half life of the benzodiazepines and does not form any active metabolites." | 1.26 | The pharmacokinetic profile of oxazepam. ( Alván, G; Odar-Cederlöf, I, 1978) |
| " During multiple dosing the accumulation of conjugates was even more pronounced, with plasma concentrations amounting to 14-61 times those of oxazepam." | 1.26 | Oxazepam disposition in uremic patients. ( Alván, G; Odar-Cederlöf, I; Sjöqvist, F; Vessman, J, 1977) |
Research
Studies (2)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Alván, G | 2 |
| Odar-Cederlöf, I | 2 |
| Vessman, J | 1 |
| Sjöqvist, F | 1 |
Other Studies
2 other studies available for oxazepam and Uremia
| Article | Year |
|---|---|
The pharmacokinetic profile of oxazepam.
Topics: Administration, Oral; Animals; Biological Availability; Dogs; Half-Life; Humans; Infusions, Parenter | 1978 |
Oxazepam disposition in uremic patients.
Topics: Administration, Oral; Half-Life; Humans; Oxazepam; Uremia | 1977 |