oxazepam has been researched along with Substance-Related Disorders in 49 studies
Oxazepam: A benzodiazepine used in the treatment of anxiety, alcohol withdrawal, and insomnia.
oxazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a hydroxy group at position 3 and phenyl group at position 5.
Substance-Related Disorders: Disorders related to substance use or abuse.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Oxazepam has a short half-life and inactive metabolites and therefore differs from most other benzodiazepines." | 3.74 | The clinical pharmacology of oxazepam. ( Lader, MH, 1978) |
| "Diazepam was categorized as producing barbiturate-like subjective effects (38." | 2.65 | Relative abuse liability of diazepam and oxazepam: behavioral and subjective dose effects. ( Bigelow, GE; Griffiths, RR; Liebson, IA; McLeod, DR; Roache, JD, 1984) |
| "Oxazepam is an anxiolytic with established clinical efficacy." | 2.38 | Oxazepam: update 1989. ( Ayd, FJ, 1990) |
| "However, withdrawal symptoms may occur in patients receiving recommended doses and/or short-term therapy." | 2.36 | Benzodiazepine withdrawal syndrome: a literature review and evaluation. ( MacKinnon, GL; Parker, WA, 1982) |
| " ND and parent OX have similar pharmacokinetic profiles." | 1.29 | Pharmacokinetics of nordiazepam in physical dependence and precipitated abstinence in dogs. ( Martin, WR; Sloan, JW; Wala, EP, 1993) |
| " We report five cases of high-dose triazolam abuse in which the daily dosage ranged from 5 to 15 mg (100-300 mg diazepam equivalent) and the duration of use ranged from 3 months to 5 years." | 1.28 | Detoxification for triazolam physical dependence. ( Sellers, EM; Sullivan, JT, 1992) |
| " 10%) and its bioavailability following oral administration is about 22%." | 1.28 | The effects of flumazenil-precipitated abstinence on the pharmacokinetics of chronic oxazepam in dogs. ( Martin, WR; Pruitt, TA; Sloan, JW; Wala, EP, 1990) |
| "Diazepam was categorized as producing barbiturate-like subjective effects more frequently than was oxazepam (54 vs." | 1.27 | Comparison of diazepam and oxazepam: preference, liking and extent of abuse. ( Bigelow, GE; Griffiths, RR; Liebson, IA; McLeod, DR; Nowowieski, P; Roache, JD, 1984) |
| " Flumazenil caused dose-related increases in the NPAS scores of both diazepam- and nordiazepam-dependent dogs; the slopes of the two dose-response lines were not different." | 1.27 | Precipitation of abstinence in nordiazepam- and diazepam-dependent dogs. ( Martin, WR; McNicholas, LF; Sloan, JW; Wala, E, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 27 (55.10) | 18.7374 |
| 1990's | 10 (20.41) | 18.2507 |
| 2000's | 5 (10.20) | 29.6817 |
| 2010's | 7 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Goeders, NE | 1 |
| Guerin, GF | 1 |
| Schmoutz, CD | 1 |
| Bertol, E | 1 |
| Mari, F | 1 |
| Boscolo Berto, R | 1 |
| Mannaioni, G | 1 |
| Vaiano, F | 1 |
| Favretto, D | 1 |
| Tvete, IF | 1 |
| Bjørner, T | 1 |
| Skomedal, T | 1 |
| Howland, RH | 2 |
| Salvatore, S | 1 |
| Røislien, J | 1 |
| Baz-Lomba, JA | 1 |
| Bramness, JG | 1 |
| El Balkhi, S | 1 |
| Chaslot, M | 1 |
| Picard, N | 1 |
| Dulaurent, S | 1 |
| Delage, M | 1 |
| Mathieu, O | 1 |
| Saint-Marcoux, F | 1 |
| Marin, SJ | 1 |
| Keith, L | 1 |
| Merrell, M | 1 |
| McMillin, GA | 1 |
| Khong, E | 1 |
| Sim, MG | 1 |
| Hulse, G | 1 |
| Cohen, ES | 1 |
| Holman, RC | 1 |
| Rosser, WW | 1 |
| MacKinnon, GL | 1 |
| Parker, WA | 1 |
| Griffiths, RR | 3 |
| McLeod, DR | 2 |
| Bigelow, GE | 3 |
| Liebson, IA | 3 |
| Roache, JD | 2 |
| Nowowieski, P | 1 |
| Walters, L | 1 |
| Nel, P | 1 |
| Martin, JR | 1 |
| Moreau, JL | 1 |
| Jenck, F | 1 |
| Simonsson, P | 1 |
| Lidén, A | 1 |
| Lindberg, S | 1 |
| Wala, EP | 3 |
| Martin, WR | 4 |
| Sloan, JW | 4 |
| McCann, MJ | 1 |
| Miotto, K | 1 |
| Rawson, RA | 1 |
| Huber, A | 1 |
| Shoptaw, S | 1 |
| Ling, W | 1 |
| Prater, CD | 1 |
| Miller, KE | 1 |
| Zylstra, RG | 1 |
| Paetzold, W | 1 |
| Eronat, V | 1 |
| Seifert, J | 1 |
| Holze, I | 1 |
| Emrich, HM | 1 |
| Schneider, U | 1 |
| Smith-Kielland, A | 1 |
| Skuterud, B | 1 |
| Olsen, KM | 1 |
| Mørland, J | 1 |
| Birmes, P | 1 |
| Chounet, V | 1 |
| Mazerolles, M | 1 |
| Cathala, B | 1 |
| Schmitt, L | 1 |
| Lauque, D | 1 |
| Solomon, D | 1 |
| Bliding, A | 2 |
| Imlah, NW | 1 |
| Lader, MH | 1 |
| Kaistha, KK | 1 |
| Tadrus, R | 1 |
| Ayd, FJ | 2 |
| Sullivan, JT | 1 |
| Sellers, EM | 1 |
| Dusci, LJ | 1 |
| Good, SM | 1 |
| Hall, RW | 1 |
| Ilett, KF | 1 |
| Pruitt, TA | 1 |
| Preston, KL | 1 |
| McNicholas, LF | 1 |
| Wala, E | 1 |
| Bergman, U | 1 |
| Kanto, J | 1 |
| Iisalo, E | 1 |
| Lehtinen, V | 1 |
| Salminen, J | 1 |
| Katz, RL | 1 |
| Blackwell, B | 1 |
| Retterstol, N | 1 |
| Mader, R | 1 |
| Schubert, H | 1 |
| Pernhaupt, G | 1 |
| Hanna, SM | 1 |
| Harry, TV | 1 |
| Greenblatt, DJ | 1 |
| Shader, RI | 1 |
8 reviews available for oxazepam and Substance-Related Disorders
| Article | Year |
|---|---|
The combination of metyrapone and oxazepam for the treatment of cocaine and other drug addictions.
Topics: Animals; Anti-Anxiety Agents; Cocaine-Related Disorders; Humans; Metyrapone; Oxazepam; Stress, Psych | 2014 |
Benzodiazepine dependence.
Topics: Anti-Anxiety Agents; Anxiety Disorders; Benzodiazepines; Clinical Protocols; Drug Tolerance; Family | 2004 |
Benzodiazepine withdrawal syndrome: a literature review and evaluation.
Topics: Anti-Anxiety Agents; Chlordiazepoxide; Diazepam; Dose-Response Relationship, Drug; Humans; Lorazepam | 1982 |
Outpatient detoxification of the addicted or alcoholic patient.
Topics: Alcohol Withdrawal Delirium; Alcoholic Intoxication; Ambulatory Care; Anti-Anxiety Agents; Chlordiaz | 1999 |
The clinical pharmacology of oxazepam.
Topics: Aggression; Anxiety; Chlordiazepoxide; Clinical Trials as Topic; Drug Evaluation; Humans; Oxazepam; | 1978 |
Oxazepam: update 1989.
Topics: Aged; Alcoholism; Alprazolam; Female; Humans; Oxazepam; Seizures; Substance Withdrawal Syndrome; Sub | 1990 |
Sedatives and tranquilizers.
Topics: Anxiety; Barbiturates; Chlordiazepoxide; Clinical Trials as Topic; Diazepam; Humans; Hypnotics and S | 1972 |
[Misuse of benzodiazepine derivatives. A review, with special reference to Norwegian data].
Topics: Chlordiazepoxide; Diazepam; Humans; Norway; Oxazepam; Substance-Related Disorders; Tranquilizing Age | 1971 |
8 trials available for oxazepam and Substance-Related Disorders
| Article | Year |
|---|---|
Relative abuse liability of diazepam and oxazepam: behavioral and subjective dose effects.
Topics: Adult; Behavior; Cognition; Diazepam; Dose-Response Relationship, Drug; Drug Tolerance; Emotions; Hu | 1984 |
[The addiction potential of benzodiazepines. Application of the results of treatment of alcohol withdrawal syndrome].
Topics: Alcohol Withdrawal Delirium; Benzodiazepines; Chlordiazepoxide; Humans; Oxazepam; Psychoses, Alcohol | 1981 |
[Detoxification of poly-substance abusers with buprenorphine. Effects on affect, anxiety, and withdrawal symptoms].
Topics: Adult; Affect; Analgesics, Non-Narcotic; Analysis of Variance; Anti-Anxiety Agents; Anxiety; Bupreno | 2000 |
Urinary excretion of diazepam metabolites in healthy volunteers and drug users.
Topics: Adult; Anti-Anxiety Agents; Chromatography, Gas; Chromatography, High Pressure Liquid; Creatinine; D | 2001 |
The clinical pharmacology of oxazepam.
Topics: Aggression; Anxiety; Chlordiazepoxide; Clinical Trials as Topic; Drug Evaluation; Humans; Oxazepam; | 1978 |
Sedatives and tranquilizers.
Topics: Anxiety; Barbiturates; Chlordiazepoxide; Clinical Trials as Topic; Diazepam; Humans; Hypnotics and S | 1972 |
Effects of different rates of absorption of two benzodiazepins on subjective and objective parameters. Significance for clinical use and risk of abuse.
Topics: Absorption; Anxiety; Diazepam; Female; Hand; Humans; Male; Oxazepam; Placebos; Pulse; Reaction Time; | 1974 |
Meprobamate: a study of irrational drug use.
Topics: Agranulocytosis; Anemia, Aplastic; Anxiety; Chlordiazepoxide; Diazepam; Humans; Meprobamate; Neuroti | 1971 |
35 other studies available for oxazepam and Substance-Related Disorders
| Article | Year |
|---|---|
A mixed MDPV and benzodiazepine intoxication in a chronic drug abuser: determination of MDPV metabolites by LC-HRMS and discussion of the case.
Topics: Adult; Alprazolam; Benzodiazepines; Benzodioxoles; Chlordiazepoxide; Chromatography, Liquid; Diazepa | 2014 |
A 5-year follow-up study of users of benzodiazepine: starting with diazepam versus oxazepam.
Topics: Adult; Anti-Anxiety Agents; Anxiety; Depression; Diazepam; Dose-Response Relationship, Drug; Drug Pr | 2016 |
Safety and Abuse Liability of Oxazepam: Is This Benzodiazepine Drug Underutilized?
Topics: Benzodiazepines; GABA Modulators; Humans; Oxazepam; Safety; Substance-Related Disorders | 2016 |
Oxazepam for the Treatment of Substance Abuse and Depression: Is it Appropriate?
Topics: Depression; Humans; Hypnotics and Sedatives; Oxazepam; Substance-Related Disorders | 2016 |
Assessing prescription drug abuse using functional principal component analysis (FPCA) of wastewater data.
Topics: Environmental Monitoring; Humans; Methadone; Methylphenidate; Models, Theoretical; Norway; Oxazepam; | 2017 |
Characterization and identification of eight designer benzodiazepine metabolites by incubation with human liver microsomes and analysis by a triple quadrupole mass spectrometer.
Topics: Adult; Benzodiazepines; Chromatography, Liquid; Designer Drugs; Humans; Lorazepam; Male; Microsomes, | 2017 |
Evaluation of a new ELISA kit for the detection of benzodiazepines in meconium.
Topics: Benzodiazepines; Calibration; Clonazepam; Enzyme-Linked Immunosorbent Assay; Female; Humans; Hypnoti | 2009 |
An integrated approach to iatrogenic drug abuse in a closed delivery system.
Topics: Adult; Aged; Anti-Anxiety Agents; Chlordiazepoxide; Diazepam; Doxepin; Drug and Narcotic Control; Dr | 1980 |
Benzodiazepine prescription to middle-aged women: it is done indiscriminately by family physicians?
Topics: Age Factors; Anti-Anxiety Agents; Canada; Diazepam; Female; Humans; Life Change Events; Marriage; Mi | 1982 |
Comparison of diazepam and oxazepam: preference, liking and extent of abuse.
Topics: Adult; Diazepam; Humans; Male; Middle Aged; Oxazepam; Reinforcement, Psychology; Substance-Related D | 1984 |
Systematic review of the benzodiazepines. Guidelines for data sheets on diazepam, chlordiazepoxide, medazepam, clorazepate, lorazepam, oxazepam, temazepam, triazolam, nitrazepam, and flurazepam. Committee on the Review of Medicines.
Topics: Benzodiazepines; Chlordiazepoxide; Clorazepate Dipotassium; Diazepam; Flurazepam; Humans; Lorazepam; | 1980 |
Precipitated withdrawal in squirrel monkeys after repeated daily oral administration of alprazolam, diazepam, flunitrazepam or oxazepam.
Topics: Administration, Oral; Alprazolam; Animals; Behavior, Animal; Diazepam; Dose-Response Relationship, D | 1995 |
Effect of beta-glucuronidase on urinary benzodiazepine concentrations determined by fluorescence polarization immunoassay.
Topics: Benzodiazepines; Chromatography, High Pressure Liquid; Fluorescence Polarization Immunoassay; Glucur | 1995 |
Pharmacokinetics of nordiazepam in physical dependence and precipitated abstinence in dogs.
Topics: Administration, Oral; Animals; Blood Proteins; Diazepam; Dogs; Female; Flumazenil; Hydrolysis; Injec | 1993 |
Outpatient non-opioid detoxification for opioid withdrawal. Who is likely to benefit?
Topics: Adolescent; Adrenergic alpha-Agonists; Adult; Ambulatory Care Facilities; Clonidine; Female; GABA Mo | 1997 |
[Self-poisoning with Datura stramonium. 3 case reports].
Topics: Adult; Anti-Anxiety Agents; Antipsychotic Agents; Datura stramonium; Dopamine Antagonists; Female; F | 2002 |
High-dose benzodiazepines in the treatment of severe neurotic anxiety.
Topics: Adult; Aged; Anti-Anxiety Agents; Anxiety Disorders; Diazepam; Female; Flurazepam; Humans; Male; Oxa | 1978 |
The abuse potential of benzodiazepines with special reference to oxazepam.
Topics: Adult; Alcoholism; Anxiety; Benzodiazepines; Female; Humans; Male; Neurotic Disorders; Oxazepam; Sub | 1978 |
The episodic nature of anxiety and its treatment with oxazepam.
Topics: Anxiety; Half-Life; Humans; Oxazepam; Substance-Related Disorders | 1978 |
Thin-layer detection of diazepam and/or chilordiazepoxide alone or in combination with major drugs of abuse in drug abuse urine screening programs.
Topics: Chlordiazepoxide; Chromatography, Thin Layer; Clorazepate Dipotassium; Diazepam; Humans; Indicators | 1978 |
Oxazepam: An overview.
Topics: Age Factors; Child, Preschool; Drug Interactions; Humans; Male; Middle Aged; Oxazepam; Substance-Rel | 1975 |
[Warning about careless prescription of ataractics and hypnotics].
Topics: Adult; Drug Prescriptions; Drug Synergism; Humans; Hypnotics and Sedatives; Male; Medication Errors; | 1976 |
Detoxification for triazolam physical dependence.
Topics: Adult; Alcoholism; Diazepam; Dose-Response Relationship, Drug; Female; Half-Life; Hospitalization; H | 1992 |
Distribution of diazepam, nordiazepam, and oxazepam between brain extraneuronal space, brain tissue, plasma, and cerebrospinal fluid in diazepam and nordiazepam dependent dogs.
Topics: Animals; Brain; Diazepam; Dogs; Extracellular Space; Female; Nordazepam; Oxazepam; Substance-Related | 1991 |
Excretion of diazepam and its metabolites in human milk during withdrawal from combination high dose diazepam and oxazepam.
Topics: Adult; Diazepam; Drug Combinations; Female; Humans; Infant; Milk, Human; Nordazepam; Oxazepam; Subst | 1990 |
The effects of flumazenil-precipitated abstinence on the pharmacokinetics of chronic oxazepam in dogs.
Topics: Administration, Oral; Animals; Biological Availability; Dogs; Drug Interactions; Female; Flumazenil; | 1990 |
Self-administration of clonidine, oxazepam, and hydromorphone by patients undergoing methadone detoxification.
Topics: Adult; Clonidine; Drug Administration Schedule; Humans; Hydromorphone; Male; Methadone; Opioid-Relat | 1985 |
Precipitation of abstinence in nordiazepam- and diazepam-dependent dogs.
Topics: Analysis of Variance; Animals; Diazepam; Dogs; Flumazenil; Nordazepam; Oxazepam; Pyrazoles; Seizures | 1988 |
Relative abuse of diazepam and oxazepam: prescription forgeries and theft/loss reports in Sweden.
Topics: Cross-Sectional Studies; Depressive Disorder; Diazepam; Drug and Narcotic Control; Drug Prescription | 1986 |
The concentrations of diazepam and its metabolites in the plasma after an acute and chronic administration.
Topics: Anxiety Disorders; Chromatography, Gas; Diazepam; Humans; Methylation; Microsomes, Liver; Oxazepam; | 1974 |
Psychotropic drugs in use today. The role of diazepam in medical practice.
Topics: Anxiety Disorders; Chlordiazepoxide; Depression; Diazepam; Drug Interactions; Drug Utilization; Fami | 1973 |
[Observation of oxazepam dependence].
Topics: Adult; Anxiety Disorders; Humans; Male; Oxazepam; Psychoses, Substance-Induced; Substance Withdrawal | 1972 |
[Oxazepam in the treatment of neurotic disorders as well as in ambulatory detoxication treatment for alcoholics and polytoxicomaniacs].
Topics: Adult; Alcoholism; Ambulatory Care; Austria; Female; Humans; Male; Methods; Neurotic Disorders; Oxaz | 1972 |
A case of oxazepam (serenid D) dependence.
Topics: Adult; Anxiety; Depression; Humans; Male; Oxazepam; Phenelzine; Substance Withdrawal Syndrome; Subst | 1972 |
Oxazepam (Serenid D) dependence.
Topics: Adult; Depression; Humans; Male; Oxazepam; Substance Withdrawal Syndrome; Substance-Related Disorder | 1972 |