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oxazepam and Sleep Initiation and Maintenance Disorders

oxazepam has been researched along with Sleep Initiation and Maintenance Disorders in 27 studies

Oxazepam: A benzodiazepine used in the treatment of anxiety, alcohol withdrawal, and insomnia.
oxazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a hydroxy group at position 3 and phenyl group at position 5.

Sleep Initiation and Maintenance Disorders: Disorders characterized by impairment of the ability to initiate or maintain sleep. This may occur as a primary disorder or in association with another medical or psychiatric condition.

Research Excerpts

ExcerptRelevanceReference
" Oxazepam and flurazepam were effective in improving some polysomnographically defined measures of nocturnal sleep in 14 patients with chronic insomnia; flurazepam produced substantial daytime sleepiness and oxazepam did not."9.05Nighttime and daytime efficacy of flurazepam and oxazepam in chronic insomnia. ( Bliwise, D; Dement, W; Greenblatt, DJ; Seidel, W, 1984)
" Oxazepam and flurazepam were effective in improving some polysomnographically defined measures of nocturnal sleep in 14 patients with chronic insomnia; flurazepam produced substantial daytime sleepiness and oxazepam did not."5.05Nighttime and daytime efficacy of flurazepam and oxazepam in chronic insomnia. ( Bliwise, D; Dement, W; Greenblatt, DJ; Seidel, W, 1984)
"Non-organic and non-psychiatric insomniacs aged between 18 and 70 years were included into the trial."2.69[Efficacy and tolerability of Baldrian versus oxazepam in non-organic and non-psychiatric insomniacs: a randomised, double-blind, clinical, comparative study]. ( Dorn, M, 2000)
"Both nitrazepam and oxazepam were found to be effective in inducing sleep and increasing sleep quality."2.67Treatment of insomnia with two benzodiazepines: a double-blind crossover study. ( Berntzen, D; Götestam, KG; Oppöyen, F, 1991)
"Three different dosage studies were carried out with midazolam in 47 institutionalized geriatric patients (17 males: mean age 82."2.65Midazolam dosage studies in institutionalized geriatric patients. ( Beck, H; Holzer, J; Salom, M, 1983)
" Recent research suggests that this is due to metabolic and pharmacokinetic differences rather than an intrinsically more favourable toxic-to-therapeutic dosage ratio."2.64The clinical activity of oxazepam. ( Cardon, A; Fouks, L; Pinalie, B; Porcheron, JB, 1978)

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-199021 (77.78)18.7374
1990's2 (7.41)18.2507
2000's4 (14.81)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ziegler, G1
Ploch, M1
Miettinen-Baumann, A1
Collet, W1
Khong, E1
Sim, MG1
Hulse, G1
Cotroneo, A1
Gareri, P1
Nicoletti, N1
Lacava, R1
Grassone, D1
Maina, E1
De Sarro, G1
Cabodi, S1
Linnoila, M1
Viukari, M1
Lamminsivu, U1
Auvinen, J1
Lapierre, YD1
Helcl, I1
Lupolover, R2
Buch, JP1
Amrein, R1
Dement, W2
Seidel, W2
Carskadon, M1
Dordain, G1
Puech, AJ1
Simon, P1
Beck, H1
Salom, M1
Holzer, J1
Ballmer, U1
Helcl, J1
Escher, J1
Pavletic, B1
Gallais, H1
Casanova, P1
Fabregat, H1
Feldmeier, C1
Kapp, W1
Conell, LJ1
Berlin, RM1
Bliwise, D1
Greenblatt, DJ1
Dorn, M1
Geiselmann, B1
Müting, D1
Fouks, L1
Pinalie, B1
Porcheron, JB1
Cardon, A1
Lescovelli, M1
Castellani, A1
Perbellini, D1
Götestam, KG1
Oppöyen, F1
Berntzen, D1
Beauchair, L1
Fontaine, R1
Baker, MI1
Oleen, MA1
Bergman, U1
Griffiths, RR1
Gillmer, RE1
Bedoret, JM1
Beaussart-Boulengé, L1
Fontan, M1
Lima, PR1
de Miranda, AP1
Vieira, CL1

Reviews

2 reviews available for oxazepam and Sleep Initiation and Maintenance Disorders

ArticleYear
Benzodiazepine dependence.
    Australian family physician, 2004, Volume: 33, Issue:11

    Topics: Anti-Anxiety Agents; Anxiety Disorders; Benzodiazepines; Clinical Protocols; Drug Tolerance; Family

2004
[Pathophysiology and therapy of altitude sickness].
    Medizinische Klinik, 1978, Dec-22, Volume: 73, Issue:51-52

    Topics: Adolescent; Adult; Altitude Sickness; Cell Membrane Permeability; Dietary Carbohydrates; Diphosphogl

1978

Trials

13 trials available for oxazepam and Sleep Initiation and Maintenance Disorders

ArticleYear
Efficacy and tolerability of valerian extract LI 156 compared with oxazepam in the treatment of non-organic insomnia--a randomized, double-blind, comparative clinical study.
    European journal of medical research, 2002, Nov-25, Volume: 7, Issue:11

    Topics: Adolescent; Adult; Aged; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Male; Middle

2002
Efficacy and side effects of lorazepam, oxazepam, and temazepam as sleeping aids in psychogeriatric inpatients.
    International pharmacopsychiatry, 1980, Volume: 15, Issue:2

    Topics: Aged; Anti-Anxiety Agents; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Lorazepam;

1980
Evaluation of the efficacy and tolerance of orally administered midazolam as hypnotic agent compared with oxazepam in the treatment of insomnia of mild to moderate severity.
    Arzneimittel-Forschung, 1981, Volume: 31, Issue:12a

    Topics: Anti-Anxiety Agents; Benzodiazepines; Clinical Trials as Topic; Double-Blind Method; Female; Humans;

1981
Midazolam dosage studies in institutionalized geriatric patients.
    British journal of clinical pharmacology, 1983, Volume: 16 Suppl 1

    Topics: Aged; Anti-Anxiety Agents; Benzodiazepines; Drug Interactions; Female; Humans; Hypnotics and Sedativ

1983
Efficacy and safety of midazolam and oxazepam in insomniacs.
    British journal of clinical pharmacology, 1983, Volume: 16 Suppl 1

    Topics: Anti-Anxiety Agents; Benzodiazepines; Clinical Trials as Topic; Double-Blind Method; Female; Humans;

1983
Midazolam and oxazepam in the treatment of insomnia in hospitalized patients.
    British journal of clinical pharmacology, 1983, Volume: 16 Suppl 1

    Topics: Anti-Anxiety Agents; Benzodiazepines; Clinical Trials as Topic; Double-Blind Method; Hospitalization

1983
Comparative clinical studies with midazolam, oxazepam and placebo.
    British journal of clinical pharmacology, 1983, Volume: 16 Suppl 1

    Topics: Adult; Aged; Anti-Anxiety Agents; Benzodiazepines; Clinical Trials as Topic; Double-Blind Method; Dr

1983
Nighttime and daytime efficacy of flurazepam and oxazepam in chronic insomnia.
    The American journal of psychiatry, 1984, Volume: 141, Issue:2

    Topics: Chronic Disease; Circadian Rhythm; Electroencephalography; Electromyography; Electrooculography; Flu

1984
[Efficacy and tolerability of Baldrian versus oxazepam in non-organic and non-psychiatric insomniacs: a randomised, double-blind, clinical, comparative study].
    Forschende Komplementarmedizin und klassische Naturheilkunde = Research in complementary and natural classical medicine, 2000, Volume: 7, Issue:2

    Topics: Adult; Aged; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Male; Middle Aged; Oxazep

2000
The clinical activity of oxazepam.
    Acta psychiatrica Scandinavica. Supplementum, 1978, Issue:274

    Topics: Alcoholism; Anxiety Disorders; Clinical Trials as Topic; Depression; Drug Evaluation; Humans; Mental

1978
A double-blind cross-over evaluation of the activity of d-oxazepam hemisuccinate sodium salt (D-7-chloro-1,3-dihydro-3-hemisuccinyloxy-5-phenyl-2H-1,4-benzodiazepine-2-one) compared to its racemic form.
    Arzneimittel-Forschung, 1976, Volume: 26, Issue:8

    Topics: Adult; Aged; Anxiety; Clinical Trials as Topic; Female; Humans; Male; Middle Aged; Oxazepam; Psychop

1976
Treatment of insomnia with two benzodiazepines: a double-blind crossover study.
    European journal of clinical pharmacology, 1991, Volume: 41, Issue:2

    Topics: Adult; Aged; Double-Blind Method; Female; Humans; Male; Middle Aged; Nitrazepam; Oxazepam; Sleep; Sl

1991
Benzoctamine and oxazepam in the management of alcohol withdrawal states. Comparison by double-blind trial.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1973, Dec-01, Volume: 47, Issue:47

    Topics: Adult; Aggression; Alcoholism; Anger; Anthracenes; Anxiety; Clinical Trials as Topic; Drive; Drug Ev

1973

Other Studies

12 other studies available for oxazepam and Sleep Initiation and Maintenance Disorders

ArticleYear
Effectiveness and safety of hypnotic drugs in the treatment of insomnia in over 70-year old people.
    Archives of gerontology and geriatrics, 2007, Volume: 44 Suppl 1

    Topics: Aged; Cognition Disorders; Dementia; Depression; Drug Administration Schedule; Female; Health Status

2007
Benzodiazepine withdrawal.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1981, Volume: 26, Issue:2

    Topics: Anti-Anxiety Agents; Anxiety; Diazepam; Drug Tolerance; Humans; Lorazepam; Oxazepam; Sleep Initiatio

1981
Daytime alertness, insomnia, and benzodiazepines.
    Sleep, 1982, Volume: 5 Suppl 1

    Topics: Adult; Anti-Anxiety Agents; Arousal; Benzodiazepines; Double-Blind Method; Flurazepam; Humans; Loraz

1982
Triazolam compared with nitrazepam and with oxazepam in insomnia: two double-blind, crossover studies analyzed sequentially.
    British journal of clinical pharmacology, 1981, Volume: 11 Suppl 1

    Topics: Adolescent; Adult; Aged; Anti-Anxiety Agents; Double-Blind Method; Female; Humans; Male; Middle Aged

1981
Withdrawal after substitution of a short-acting for a long-acting benzodiazepine.
    JAMA, 1983, Nov-25, Volume: 250, Issue:20

    Topics: Anti-Anxiety Agents; Anxiety; Chronic Disease; Delayed-Action Preparations; Diazepam; Flurazepam; Ha

1983
Informed refusal: the patient's influence on long-term treatment.
    Pharmacopsychiatry, 1994, Volume: 27, Issue:Suppl. 1

    Topics: Altruism; Antipsychotic Agents; Beneficence; Chronic Disease; Decision Making; Disclosure; Ethics, M

1994
Choice of a benzodiazepine for treatment of anxiety or insomnia.
    The Medical letter on drugs and therapeutics, 1977, Jun-17, Volume: 19, Issue:12

    Topics: Anxiety; Benzodiazepines; Chlordiazepoxide; Diazepam; Humans; Oxazepam; Sleep Initiation and Mainten

1977
Benzodiazepines: half-life and daytime sleepiness.
    The American journal of psychiatry, 1985, Volume: 142, Issue:6

    Topics: Anti-Anxiety Agents; Circadian Rhythm; Flurazepam; Half-Life; Humans; Oxazepam; Sleep; Sleep Initiat

1985
The use of benzodiazepine hypnotics in the elderly.
    Pharmacotherapy, 1988, Volume: 8, Issue:4

    Topics: Adolescent; Age Factors; Aged; Aged, 80 and over; Canada; Drug Interactions; Drug Prescriptions; Dru

1988
Relative abuse of diazepam and oxazepam: prescription forgeries and theft/loss reports in Sweden.
    Drug and alcohol dependence, 1986, Volume: 16, Issue:4

    Topics: Cross-Sectional Studies; Depressive Disorder; Diazepam; Drug and Narcotic Control; Drug Prescription

1986
[Polygraphic study of night sleep under oxazepam].
    Lille medical : journal de la Faculte de medecine et de pharmacie de l'Universite de Lille, 1972, Volume: 17

    Topics: Adult; Electroencephalography; Humans; Male; Oxazepam; Sleep; Sleep Initiation and Maintenance Disor

1972
[Results of clinical findings on the use of a sympatholytic in cases of anxiety neuroses].
    Hospital (Rio de Janeiro, Brazil), 1968, Volume: 74, Issue:6

    Topics: Anxiety Disorders; Criminal Psychology; Humans; Hysteria; Male; Oxazepam; Paranoid Disorders; Psycho

1968