oxazepam has been researched along with Pregnancy in 53 studies
Oxazepam: A benzodiazepine used in the treatment of anxiety, alcohol withdrawal, and insomnia.
oxazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a hydroxy group at position 3 and phenyl group at position 5.
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
Excerpt | Relevance | Reference |
---|---|---|
" Prenatal oxazepam (15 mg/kg, given per os twice daily on days 12-16 of pregnancy) did not influence hot-plate responding and morphine analgesia at any of the test ages." | 7.67 | Morphine effects on activity and pain reactivity of developing mice with or without late prenatal oxazepam exposure. ( Alleva, E; Bignami, G; Laviola, G, 1987) |
" In 66 first-trimester pregnant women, who had applied for legal termination of the pregnancy, we have calculated different pharmacokinetic parameters of two benzodiazepine derivatives, diazepam and oxazepam, after administration of a single oral dose of 10 or 25 mg to the mother." | 5.27 | Pharmacokinetics and distribution of diazepam and oxazepam in early pregnancy. ( Jørgensen, NP; Thurmann-Nielsen, E; Walstad, RA, 1988) |
" Outbred CD-1 mouse pups, prenatally exposed to either the vehicle (VEH) or oxazepam (OX, 15 mg/kg twice/day on pregnancy days 12-16) and fostered to untreated dams at birth, were offered as a stimulus on postnatal days 4, 6, and 8 to four groups of females that differed in maternal experience: virgin, experienced virgin females, primiparae, and biparae." | 3.69 | Induction of maternal behavior by mouse neonates: influence of dam parity and prenatal oxazepam exposure. ( Alleva, E; Laviola, G; Petruzzi, S; Rankin, J, 1994) |
" Prenatal oxazepam (15 mg/kg, given per os twice daily on days 12-16 of pregnancy) did not influence hot-plate responding and morphine analgesia at any of the test ages." | 3.67 | Morphine effects on activity and pain reactivity of developing mice with or without late prenatal oxazepam exposure. ( Alleva, E; Bignami, G; Laviola, G, 1987) |
"Oxazepam treatment of primiparous mouse dams on days 12-16 of pregnancy (15 mg/kg p." | 3.67 | Prenatal benzodiazepine effects in mice: postnatal behavioral development, response to drug challenges, and adult discrimination learning. ( Alleva, E; Bignami, G, 1986) |
"A benzodiazepine (oxazepam) was given to nulliparous mice on days 12-16 of pregnancy, and the development and young adult behaviour of the offspring were studied." | 3.67 | Short-, medium-, and long-term effects of prenatal oxazepam on neurobehavioural development of mice. ( Alleva, E; Bignami, G; Laviola, G; Tirelli, E, 1985) |
"Knowledge of the pharmacokinetic properties of the benzodiazepines is playing an increasingly important role in their use during pregnancy, labour and lactation." | 2.36 | Use of benzodiazepines during pregnancy, labour and lactation, with particular reference to pharmacokinetic considerations. ( Kanto, JH, 1982) |
"The main recommendations for treatment of pruritus during pregnancy are to begin with topical treatment; emollient bath additives, moisturizing cream, talc." | 1.29 | Strategy of treatment of pruritus during pregnancy. The Drugs and Pregnancy Study Group. ( , 1994) |
"Oxazepam was readily absorbed and peak plasma concentrations were similar to those in healthy non-pregnant volunteers." | 1.26 | Pharmacokinetics of oxazepam given during labour. ( Lunell, NO; Rane, A; Sundwall, A; Tomson, G, 1978) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 41 (77.36) | 18.7374 |
1990's | 10 (18.87) | 18.2507 |
2000's | 2 (3.77) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Marin, SJ | 1 |
Keith, L | 1 |
Merrell, M | 1 |
McMillin, GA | 1 |
Swortfiguer, D | 1 |
Cissoko, H | 1 |
Giraudeau, B | 1 |
Jonville-Béra, AP | 1 |
Bensouda, L | 1 |
Autret-Leca, E | 1 |
Hokari, S | 4 |
Manzo, L | 8 |
De Bernardi, M | 7 |
Bertè, F | 7 |
Kanto, JH | 1 |
Olive, G | 1 |
Rey, E | 1 |
Saito, H | 1 |
Kobayashi, H | 1 |
Takeno, S | 1 |
Sakai, T | 1 |
Pacifici, GM | 1 |
Rane, A | 5 |
Kangas, L | 3 |
Erkkola, R | 4 |
Kanto, J | 6 |
Eronen, M | 1 |
Tomson, G | 4 |
Dell'Omo, G | 2 |
Wolfer, D | 1 |
Alleva, E | 10 |
Lipp, HP | 2 |
Laviola, G | 7 |
Petruzzi, S | 2 |
Rankin, J | 1 |
Ricceri, L | 1 |
Calamandrei, G | 1 |
Chiarotti, F | 1 |
Fiore, M | 1 |
Piiroinen, O | 1 |
Drury, KA | 1 |
Spalding, E | 1 |
Donaldson, D | 1 |
Rutherford, D | 1 |
Scrollini, F | 1 |
Caliari, S | 1 |
Romano, A | 1 |
Torchio, P | 1 |
Lunell, NO | 2 |
Sundwall, A | 3 |
Mansikka, M | 1 |
Allonen, H | 1 |
Laegreid, L | 1 |
Hagberg, G | 1 |
Lundberg, A | 1 |
Pick, CG | 1 |
Yanai, J | 1 |
Bignami, G | 4 |
Scheinin, M | 1 |
Jørgensen, NP | 1 |
Thurmann-Nielsen, E | 1 |
Walstad, RA | 1 |
Waldenström, U | 1 |
Sundelin, C | 1 |
Lindmark, G | 1 |
Tirelli, E | 1 |
Browne, TR | 1 |
Penry, JK | 1 |
Sellman, R | 2 |
Dundee, JW | 1 |
Haslett, WH | 1 |
Mascherpa, P | 3 |
Berte', F | 1 |
Benzi, G | 3 |
Owen, G | 1 |
Smith, TH | 1 |
Agersborg, HP | 1 |
Schwarz, HJ | 1 |
Beretić, T | 1 |
Schleith, K | 1 |
Lehmann, M | 1 |
Gerlach, W | 1 |
6 reviews available for oxazepam and Pregnancy
Article | Year |
---|---|
Use of benzodiazepines during pregnancy, labour and lactation, with particular reference to pharmacokinetic considerations.
Topics: Anti-Anxiety Agents; Chlordiazepoxide; Clorazepate Dipotassium; Diazepam; Female; Flunitrazepam; Hum | 1982 |
[Benzodiazepines and pregnancy. Transplacental passage, labor and lactation].
Topics: Anti-Anxiety Agents; Biotransformation; Chlordiazepoxide; Clorazepate Dipotassium; Diazepam; Female; | 1983 |
On mouse pups and their lactating dams: behavioral consequences of early exposure to oxazepam and interacting factors.
Topics: Animals; Animals, Suckling; Behavior, Animal; Female; GABA Modulators; Lactation; Maternal Behavior; | 1996 |
Early and late discharge after hospital birth. Health of mother and infant in the postpartum period.
Topics: Analgesics; Female; Hospitalization; Humans; Hypnotics and Sedatives; Infant Mortality; Infant, Newb | 1987 |
Benzodiazepines in the treatment of epilepsy. A review.
Topics: Adult; Animals; Anticonvulsants; Chlordiazepoxide; Diazepam; Disease Models, Animal; Eclampsia; Elec | 1973 |
The benzodiazepines. A review of their actions and uses relative to anaesthetic practice.
Topics: Amnesia; Anesthesia; Anesthesia, Intravenous; Anesthesia, Obstetrical; Anticonvulsants; Benzazepines | 1970 |
2 trials available for oxazepam and Pregnancy
Article | Year |
---|---|
Oral oxazepam as a premedicant in minor surgery.
Topics: Abortion, Spontaneous; Administration, Oral; Adult; Double-Blind Method; Female; Humans; Middle Aged | 1979 |
Early and late discharge after hospital birth. Health of mother and infant in the postpartum period.
Topics: Analgesics; Female; Hospitalization; Humans; Hypnotics and Sedatives; Infant Mortality; Infant, Newb | 1987 |
46 other studies available for oxazepam and Pregnancy
Article | Year |
---|---|
Evaluation of a new ELISA kit for the detection of benzodiazepines in meconium.
Topics: Benzodiazepines; Calibration; Clonazepam; Enzyme-Linked Immunosorbent Assay; Female; Humans; Hypnoti | 2009 |
[Neonatal consequences of benzodiazepines used during the last month of pregnancy].
Topics: Adult; Benzodiazepines; Drug Monitoring; Female; GABA Modulators; Hospitalization; Humans; Hypoventi | 2005 |
[Organotropism of oxazepam (7-chloro-1,3-dihydro-3-hydroxy-5-phenyl-2H-1,4-benzodiazepin-2-one) and of its glycurono-derivative in the guinea-pig at the maternal and fetal level].
Topics: Animals; Brain; Female; Fetus; Glucuronates; Guinea Pigs; Kidney; Liver; Lung; Muscles; Organ Specif | 1967 |
Fetal toxicity of benzodiazepines in rats.
Topics: Abnormalities, Drug-Induced; Animals; Anti-Anxiety Agents; Chlordiazepoxide; Clonazepam; Diazepam; F | 1984 |
Renal glucuronidation of morphine in the human foetus.
Topics: Female; Fetus; Glucuronates; Humans; Kidney; Morphine; Oxazepam; Pregnancy; Salicylamides | 1982 |
Transfer of free and conjugated oxazepam across the human placenta.
Topics: Adult; Amniotic Fluid; Female; Fetal Blood; Humans; Maternal-Fetal Exchange; Oxazepam; Pregnancy; Um | 1980 |
Prenatal and neonatal drug metabolism in man.
Topics: Adult; Biotransformation; Female; Fetus; Gestational Age; Half-Life; Humans; Infant, Newborn; Kineti | 1980 |
Impaired acquisition of swimming navigation in adult mice exposed prenatally to oxazepam.
Topics: Animals; Female; Male; Maze Learning; Mice; Oxazepam; Pregnancy; Prenatal Exposure Delayed Effects; | 1993 |
Induction of maternal behavior by mouse neonates: influence of dam parity and prenatal oxazepam exposure.
Topics: Animals; Animals, Newborn; Female; Grooming; Maternal Behavior; Mice; Motor Activity; Nesting Behavi | 1994 |
Strategy of treatment of pruritus during pregnancy. The Drugs and Pregnancy Study Group.
Topics: Administration, Topical; Female; France; Histamine H1 Antagonists; Humans; Ointments; Oxazepam; Preg | 1994 |
Prenatal oxazepam affects passive avoidance performance of preweaning mice.
Topics: Animals; Animals, Suckling; Avoidance Learning; Female; Male; Mice; Mice, Inbred Strains; Oxazepam; | 1994 |
Limited changes of mouse maternal care after prenatal oxazepam: dissociation from pup-related stimulus perception.
Topics: Animals; Female; Male; Mice; Nesting Behavior; Oxazepam; Perception; Pregnancy; Prenatal Exposure De | 1995 |
A comparison of behavioural effects of prenatally administered oxazepam in mice exposed to open-fields in the laboratory and the real world.
Topics: Animals; Behavior, Animal; Exploratory Behavior; Female; GABA Modulators; Male; Mice; Oxazepam; Preg | 1995 |
Feto-maternal concentrations of diazepam and W-demethyldiazepam after intra-amniotic diazepam injection.
Topics: Adolescent; Adult; Amniotic Fluid; Brain Chemistry; Diazepam; Female; Fetal Blood; Humans; Injection | 1976 |
IARC monographs on the evaluation of the carcinogenic risk of chemicals to man: some miscellaneous pharmaceutical substances.
Topics: Acriflavine; Animals; Anthralin; Aurothioglucose; Carcinogens; Chloroquine; Diazepam; Ethanolamines; | 1977 |
Floppy-infant syndrome: Is oxazepam the answer?
Topics: Diazepam; Female; Humans; Infant, Newborn; Infant, Newborn, Diseases; Maternal-Fetal Exchange; Muscl | 1977 |
Toxicological and pharmacological investigations of pinazepam (7-chloro-1-propargyl-5-phenyl-3H-1,4-benzodiazepin-2-one): a new psychotherapeutic agent.
Topics: Abnormalities, Drug-Induced; Aggression; Analgesia; Animals; Anti-Anxiety Agents; Blood Pressure; Ca | 1975 |
Pharmacokinetics of oxazepam given during labour.
Topics: Administration, Oral; Female; Half-Life; Humans; Infant, Newborn; Labor, Obstetric; Maternal-Fetal E | 1978 |
[Oxazepam withdrawal in the neonatal period].
Topics: Adult; Female; Humans; Infant, Newborn; Infant, Newborn, Diseases; Male; Maternal-Fetal Exchange; Ox | 1979 |
Placental passage of oxazepam and its metabolism in mother and newborn.
Topics: Adult; Female; Fetal Blood; Half-Life; Humans; Infant, Newborn; Kinetics; Maternal-Fetal Exchange; O | 1979 |
Drug metabolism in the rabbit lung during pregnancy and in the perinatal period.
Topics: Aminopyrine; Animals; Female; Liver; Lung; Oxazepam; Phenobarbital; Pregnancy; Pregnancy, Animal; Ra | 1975 |
Neurodevelopment in late infancy after prenatal exposure to benzodiazepines--a prospective study.
Topics: Abnormalities, Drug-Induced; Anti-Anxiety Agents; Arousal; Body Height; Body Weight; Cephalometry; D | 1992 |
Eight-arm maze performance, neophobia, and hippocampal cholinergic alterations after prenatal oxazepam in mice.
Topics: Amphetamine; Animals; Anxiety; Behavior, Animal; Dose-Response Relationship, Drug; Exploratory Behav | 1992 |
Interacting effects of oxazepam in late pregnancy and fostering procedure on mouse maternal behavior.
Topics: Animals; Cues; Exploratory Behavior; Female; Maternal Behavior; Mice; Motor Activity; Nesting Behavi | 1991 |
Placental and blood-CSF transfer of orally administered diazepam in the same person.
Topics: Adult; Biotransformation; Diazepam; Female; Fetal Blood; Humans; Maternal-Fetal Exchange; Nordazepam | 1987 |
Morphine effects on activity and pain reactivity of developing mice with or without late prenatal oxazepam exposure.
Topics: Aging; Animals; Female; Male; Mice; Mice, Inbred Strains; Models, Psychological; Morphine; Oxazepam; | 1987 |
Pharmacokinetics and distribution of diazepam and oxazepam in early pregnancy.
Topics: Adolescent; Adult; Diazepam; Female; Humans; Oxazepam; Pregnancy; Pregnancy Trimester, First | 1988 |
Prenatal benzodiazepine effects in mice: postnatal behavioral development, response to drug challenges, and adult discrimination learning.
Topics: Amphetamine; Animals; Avoidance Learning; Behavior, Animal; Benzodiazepines; Discrimination Learning | 1986 |
Short-, medium-, and long-term effects of prenatal oxazepam on neurobehavioural development of mice.
Topics: Amphetamine; Animals; Avoidance Learning; Behavior, Animal; Female; Growth Disorders; Learning Disab | 1985 |
Letter: Perinatal metabolism of diazepam.
Topics: Diazepam; Female; Humans; Injections, Intravenous; Maternal-Fetal Exchange; Oxazepam; Pregnancy | 1974 |
Letter: Perinatal metabolism of diazepam.
Topics: Diazepam; Female; Humans; Infant, Newborn; Maternal-Fetal Exchange; Milk, Human; Oxazepam; Pregnancy | 1974 |
Studies on drug organotropism and drug-metabolizing activity in the fetus and the newborn.
Topics: Amitriptyline; Animals; Anti-Bacterial Agents; Brain; Enzymes; Extracorporeal Circulation; Female; F | 1968 |
Ability of the placenta to metabolize oxazepam and aminopyrine before and after drug stimulation.
Topics: Aminopyrine; Animals; Female; Glucuronates; In Vitro Techniques; Oxazepam; Phenobarbital; Placenta; | 1969 |
[Aspects of iatrogenic pharmacology and toxicology at the fetal level].
Topics: Aminopyrine; Amitriptyline; Animals; Anti-Bacterial Agents; Antipyrine; Diazepam; Dogs; Female; Feta | 1969 |
Toxicity of some benzodiazepine compounds with CNS activity.
Topics: Alkaline Phosphatase; Animals; Benzazepines; Blood Chemical Analysis; Blood Glucose; Breeding; Centr | 1970 |
Developmental patterns of drug metabolism in liver and in some non-hepatic tissues of fetal and newborn rabbits.
Topics: Aminopyrine; Animals; Biotransformation; Female; Fetus; Humans; Infant, Newborn; Liver; Maternal-Fet | 1970 |
[Sedation and spasmolysis in the puerperium].
Topics: Adult; Female; Humans; Oxazepam; Pregnancy; Puerperal Disorders; Scopolamine | 1970 |
[Teratogenesis and drug control].
Topics: Abnormalities, Drug-Induced; Aminosalicylic Acids; Androgens; Animals; Chlordiazepoxide; Drug and Na | 1967 |
[Remarks on therapy of psychosomatic diseases in gynecology and obstetrics].
Topics: Adolescent; Adult; Aged; Female; Genital Diseases, Female; Humans; Middle Aged; Oxazepam; Pregnancy; | 1967 |
Investigation on tissue distribution and metabolism of oxazepam in pregnant guinea-pig and rat.
Topics: Animals; Brain Chemistry; Female; Fetus; Glucuronates; Guinea Pigs; Liver; Lung; Oxazepam; Pregnancy | 1968 |
[Studies of fetal pharmacology. 3. Possibilities of using the technic of "organs isolated in situ" in the fetus and newborn infant].
Topics: Aminopyrine; Female; Fetus; Humans; Infant, Newborn; Organ Specificity; Oxazepam; Pregnancy | 1968 |
[Metabolic transformation of oxazepam and of aminopyrine in the rabbit placenta at various periods of pregnancy].
Topics: Aminopyrine; Animals; Female; Oxazepam; Placenta; Pregnancy; Pregnancy, Animal; Rabbits | 1968 |
[Effects of luminal and oxazepam on drug-metabolizing processes of the rabbit placenta in various periods of pregnancy].
Topics: Aminopyrine; Animals; Female; Oxazepam; Phenobarbital; Placenta; Pregnancy; Pregnancy, Animal; Rabbi | 1968 |
Oxazepam glucuronidation "in vitro" in some maternal and fetal tissues of the rat. Effects of pretreatment with oxazepam and phenobarbital.
Topics: Animals; Female; Fetus; Glucuronates; Guinea Pigs; Liver; Oxazepam; Phenobarbital; Pregnancy; Pregna | 1969 |
[Oxazepam, current medication for anxiety in general medicine].
Topics: Adult; Antidepressive Agents; Anxiety; Female; Humans; Male; Middle Aged; Oxazepam; Pregnancy | 1966 |
[The control of functional disorders of female organs by Tranquo-Buscopan].
Topics: Adolescent; Adult; Antidepressive Agents; Female; Genital Diseases, Female; Humans; Middle Aged; Mus | 1966 |