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oxazepam and Obesity

oxazepam has been researched along with Obesity in 2 studies

Oxazepam: A benzodiazepine used in the treatment of anxiety, alcohol withdrawal, and insomnia.
oxazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a hydroxy group at position 3 and phenyl group at position 5.

Obesity: A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).

Research Excerpts

ExcerptRelevanceReference
"The influence of obesity on the distribution or clearance of lorazepam and oxazepam, two benzodiazepines biotransformed by glucuronide conjugation, was studied in a series of obese subjects (mean weight 113 kg; mean percent IBW 179%) and healthy controls of normal body habitus matched for age and sex."7.66Enhanced glucuronide conjugation of drugs in obesity: studies of lorazepam, oxazepam, and acetaminophen. ( Abernethy, DR; Divoll, M; Greenblatt, DJ; Shader, RI, 1983)
" The elimination half-life increased to 1."1.28Influence of a very low calorie diet on the clearance of oxazepam and antipyrine in man. ( Andreasen, F; Dragsted, J; Døssing, M; Loft, S; Sonne, J, 1989)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19902 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Abernethy, DR1
Greenblatt, DJ1
Divoll, M1
Shader, RI1
Sonne, J1
Dragsted, J1
Loft, S1
Døssing, M1
Andreasen, F1

Other Studies

2 other studies available for oxazepam and Obesity

ArticleYear
Enhanced glucuronide conjugation of drugs in obesity: studies of lorazepam, oxazepam, and acetaminophen.
    The Journal of laboratory and clinical medicine, 1983, Volume: 101, Issue:6

    Topics: Acetaminophen; Adult; Aged; Anti-Anxiety Agents; Female; Glucuronates; Humans; Lorazepam; Male; Midd

1983
Influence of a very low calorie diet on the clearance of oxazepam and antipyrine in man.
    European journal of clinical pharmacology, 1989, Volume: 36, Issue:4

    Topics: Adult; Antipyrine; Body Weight; Chromatography, High Pressure Liquid; Diet, Reducing; Energy Intake;

1989