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oxazepam and Kidney Diseases

oxazepam has been researched along with Kidney Diseases in 5 studies

Oxazepam: A benzodiazepine used in the treatment of anxiety, alcohol withdrawal, and insomnia.
oxazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a hydroxy group at position 3 and phenyl group at position 5.

Kidney Diseases: Pathological processes of the KIDNEY or its component tissues.

Research Excerpts

ExcerptRelevanceReference
" The pharmacodynamic parameters from these models were not altered in renal dysfunction."1.30Single dose pharmacokinetics and pharmacodynamics of oxazepam in normal and renal dysfunction rats. ( Aiba, T; Hatanaka, T; Katayama, K; Koizumi, T; Srivastava, K, 1999)
"Oxazepam binding was unaffected by the presence of its glucuronide conjugates but was inhibited by fatty acids."1.27Protein binding of oxazepam and its glucuronide conjugates to human albumin. ( Boudinot, FD; Homon, CA; Jusko, WJ; Ruelius, HW, 1985)
"Oxazepam was undialyzable; since unbound oxazepam disposition kinetics are not altered, no dosage adjustment for patients is necessary."1.26Renal disease, age, and oxazepam kinetics. ( Chiang, ST; Koepke, HH; Murray, TG; Walker, BR, 1981)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19904 (80.00)18.7374
1990's1 (20.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Vree, TB1
Hekster, CA1
van der Kleijn, E1
Murray, TG1
Chiang, ST1
Koepke, HH1
Walker, BR1
Srivastava, K1
Hatanaka, T1
Aiba, T1
Katayama, K1
Koizumi, T1
Kangas, L1
Kanto, J1
Forsström, J1
Iisalo, E1
Boudinot, FD1
Homon, CA1
Jusko, WJ1
Ruelius, HW1

Other Studies

5 other studies available for oxazepam and Kidney Diseases

ArticleYear
Significance of apparent half-lives of a metabolite with a higher elimination rate than its parent drug.
    Drug intelligence & clinical pharmacy, 1982, Volume: 16, Issue:2

    Topics: Diazepam; Glucuronates; Half-Life; Humans; Kidney Diseases; Metabolic Clearance Rate; Oxazepam; Phar

1982
Renal disease, age, and oxazepam kinetics.
    Clinical pharmacology and therapeutics, 1981, Volume: 30, Issue:6

    Topics: Adult; Age Factors; Aged; Humans; Kidney; Kidney Diseases; Kinetics; Middle Aged; Oxazepam; Renal Di

1981
Single dose pharmacokinetics and pharmacodynamics of oxazepam in normal and renal dysfunction rats.
    Biological & pharmaceutical bulletin, 1999, Volume: 22, Issue:6

    Topics: Animals; Anti-Anxiety Agents; Kidney Diseases; Male; Oxazepam; Rats; Rats, Wistar; Receptors, GABA-A

1999
The protein binding of diazepam and N-demethyldiazepam in patients with poor renal function.
    Clinical nephrology, 1976, Volume: 5, Issue:3

    Topics: Adolescent; Adult; Aged; Creatinine; Diazepam; Female; Humans; Kidney Diseases; Male; Middle Aged; O

1976
Protein binding of oxazepam and its glucuronide conjugates to human albumin.
    Biochemical pharmacology, 1985, Jun-15, Volume: 34, Issue:12

    Topics: Glucuronates; Humans; In Vitro Techniques; Kidney Diseases; Nitrophenols; Oxazepam; Protein Binding;

1985