oxazepam has been researched along with Drug Withdrawal Symptoms in 72 studies
Oxazepam: A benzodiazepine used in the treatment of anxiety, alcohol withdrawal, and insomnia.
oxazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a hydroxy group at position 3 and phenyl group at position 5.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A patient developed severe anxiety, moodswing, depression, and thinking disorder 24 hours after abruptly stopping oxazepam, of which he had taken 30 mg 3 times a day for two months, for anxiety and panic attacks." | 3.66 | Abstinence syndrome from therapeutic doses of oxazepam. ( Kulik, AV; Wilbur, R, 1983) |
| "Although cocaine dependence affects an estimated 1." | 2.77 | Effects of the combination of metyrapone and oxazepam on cocaine craving and cocaine taking: a double-blind, randomized, placebo-controlled pilot study. ( Casso, S; DeMuth, G; Fox, BS; Goeders, NE; Hefti, F; Kablinger, AS; Lindner, MA; McCarthy, BG; McNair, LA, 2012) |
| "The potential use of FLU to treat BZD withdrawal symptoms has also been evaluated tentatively in clinical studies." | 2.70 | Intravenous flumazenil versus oxazepam tapering in the treatment of benzodiazepine withdrawal: a randomized, placebo-controlled study. ( Brewer, C; Gerra, G; Giusti, F; Moi, G; Zaimovic, A, 2002) |
| "The progression in severity of withdrawal symptoms (increase in CIWA-Ar above baseline) was also significantly greater in the placebo group (p < 0." | 2.70 | Divalproex sodium in alcohol withdrawal: a randomized double-blind placebo-controlled clinical trial. ( Baer, JS; Malte, CA; Reoux, JP; Saxon, AJ; Sloan, KL, 2001) |
| "Withdrawal symptoms were the highest during the first assessment of the day, at the time of BUP administration." | 2.68 | A protocol to switch high-dose, methadone-maintained subjects to buprenorphine. ( Connerney, I; Fischman, MW; Foltin, RW; Levin, FR, 1997) |
| "Among patients who had withdrawal symptoms at baseline, vital signs became normal more rapidly in the patients receiving atenolol, and their abnormal behavioral characteristics also resolved more rapidly." | 2.66 | The efficacy of atenolol in the outpatient management of the alcohol withdrawal syndrome. Results of a randomized clinical trial. ( Gottlieb, LD; Horwitz, RI; Kraus, ML, 1989) |
| "Among patients who had withdrawal symptoms at baseline, vital signs became normal more rapidly in the patients receiving atenolol; abnormal behavior and clinical characteristics also resolved more rapidly." | 2.66 | The role of beta blockers in alcohol withdrawal syndrome. ( Gottlieb, LD, 1988) |
| "Some withdrawal symptoms were distinct from those of anxiety (e." | 2.66 | Withdrawal reaction after long-term therapeutic use of benzodiazepines. ( Busto, U; Cappell, H; Naranjo, CA; Sanchez-Craig, M; Sellers, EM; Sykora, K, 1986) |
| "3." | 2.65 | Benzodiazepine withdrawal effects. ( Chang, H; Fleuri, D; McClure, DJ; Pecknold, JC, 1982) |
| "Oxazepam is an anxiolytic with established clinical efficacy." | 2.38 | Oxazepam: update 1989. ( Ayd, FJ, 1990) |
| "However, withdrawal symptoms may occur in patients receiving recommended doses and/or short-term therapy." | 2.36 | Benzodiazepine withdrawal syndrome: a literature review and evaluation. ( MacKinnon, GL; Parker, WA, 1982) |
| " Bases for selection include: (1) availability of other than oral dosage forms; (2) differences in additive effect with alcohol in producing central nervous system depression; (3) differences in anticonvulsant effect; and (4) differences in duration of effect in the body (ie, half-life)." | 2.36 | Selection among benzodiazepines for alcohol withdrawal. ( Keeler, MH; Miller, WC, 1977) |
| "Data were modeled with a 1-compartment pharmacokinetic model." | 1.43 | Population Pharmacokinetics of High-Dose Oxazepam in Alcohol-Dependent Patients: Is There a Risk of Accumulation? ( Imbert, B; Liachenko, N; Marsot, A; Simon, N, 2016) |
| "Corticosterone levels were significantly different at the end of the 15-min session, but not following the 2-h session." | 1.39 | Combinations of oxazepam and metyrapone attenuate cocaine and methamphetamine cue reactivity. ( Cornett, EM; Goeders, NE; Guerin, GF; Keller, CM, 2013) |
| "Oxazepam is a safe, efficient and cheap drug for the treatment of alcohol withdrawal symptoms, but controlled studies are needed to compare its effectiveness with that of clomethiazol." | 1.36 | Oxazepam versus clomethiazol in alcohol withdrawal treatment. ( de Millas, W; Ganzer, F; Haasen, C; Kuhn, S, 2010) |
| "Despite similar intensity of alcohol withdrawal symptoms, ALC/COC subjects received less oxazepam to treat alcohol withdrawal symptoms compared to ALC subjects." | 1.31 | Concurrent cocaine withdrawal alters alcohol withdrawal symptoms. ( Insua, A; Kaempf, G; Kampman, KM; Lipkin, C; O'Brien, CP; Pettinati, H; Sparkman, T; Turk, E; Volpicelli, J, 2002) |
| " ND and parent OX have similar pharmacokinetic profiles." | 1.29 | Pharmacokinetics of nordiazepam in physical dependence and precipitated abstinence in dogs. ( Martin, WR; Sloan, JW; Wala, EP, 1993) |
| " Drug was most often given on a fixed dosing schedule with additional medication "as needed" (52% of the programs)." | 1.29 | Alcohol withdrawal: a nationwide survey of inpatient treatment practices. ( Friedman, LS; Mayo-Smith, MF; Saitz, R, 1995) |
| " We report five cases of high-dose triazolam abuse in which the daily dosage ranged from 5 to 15 mg (100-300 mg diazepam equivalent) and the duration of use ranged from 3 months to 5 years." | 1.28 | Detoxification for triazolam physical dependence. ( Sellers, EM; Sullivan, JT, 1992) |
| "Diazepam and abecarnil were administered at doses which, based on previous experiments on anticonvulsant activity, resulted in about equieffective drug concentrations during treatment." | 1.28 | Withdrawal precipitation by benzodiazepine receptor antagonists in dogs chronically treated with diazepam or the novel anxiolytic and anticonvulsant beta-carboline abecarnil. ( Hönack, D; Löscher, W, 1992) |
| " for 14 days) the corresponding dose-response lines were shifted to the right suggesting tolerance development." | 1.27 | Subacute benzodiazepine treatment: observations on behavioural tolerance and withdrawal. ( Gonzalez, JP; McCulloch, AJ; Nicholls, PJ; Sewell, RD; Tekle, A, 1984) |
| "However, as most alcohol withdrawal seizures occurred immediately before admission, the overall seizure incidence was higher (10%)." | 1.27 | Should alcohol withdrawal seizures be treated with anti-epileptic drugs? ( Hillbom, ME; Hjelm-Jäger, M, 1984) |
| " Flumazenil caused dose-related increases in the NPAS scores of both diazepam- and nordiazepam-dependent dogs; the slopes of the two dose-response lines were not different." | 1.27 | Precipitation of abstinence in nordiazepam- and diazepam-dependent dogs. ( Martin, WR; McNicholas, LF; Sloan, JW; Wala, E, 1988) |
| "A 55 year old man developed an acute confusional state with grossly impaired short-term memory accompanied by a Status Petit Mal epilepsy pattern on EEG, one to two weeks after abruptly discontinuing a large amount of oxazepam and a smaller amount of alcohol." | 1.27 | Acute confusional state with status petit mal as a withdrawal syndrome--and five year follow-up. ( Billings, RF; Hersch, EL, 1988) |
| " The chronic use of benzodiazepines for eight months or longer prior to substitution or withdrawal appears to place the patient at a higher risk of incurring withdrawal phenomena." | 1.27 | Severe withdrawal syndrome after substitution of a short-acting benzodiazepine for a long-acting benzodiazepine. ( Berwish, NJ; Bond, WS; Swift, B, 1985) |
| "Dogs, surgically implanted with a chronic gastric fistula, were chronically dosed with N-desmethyldiazepam (32 mg/kg/day) in four divided doses to attain N-desmethyldiazepam plasma levels comparable to those observed in dogs dependent on diazepam (60 mg/kg/day)." | 1.27 | N-desmethyldiazepam physical dependence in dogs. ( Martin, WR; McNicholas, LF; Pruitt, TA, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 40 (55.56) | 18.7374 |
| 1990's | 15 (20.83) | 18.2507 |
| 2000's | 7 (9.72) | 29.6817 |
| 2010's | 9 (12.50) | 24.3611 |
| 2020's | 1 (1.39) | 2.80 |
| Authors | Studies |
|---|---|
| Mäkinen, VN | 1 |
| Hansen, KB | 1 |
| Knudsen, ST | 1 |
| Verthein, U | 1 |
| Kuhn, S | 2 |
| Gabriel, K | 1 |
| Mautsch, U | 1 |
| Reimer, J | 1 |
| Behrendt, K | 1 |
| Martinez, L | 1 |
| Vorspan, F | 1 |
| Declèves, X | 1 |
| Azuar, J | 1 |
| Fortias, M | 1 |
| Questel, F | 1 |
| Dereux, A | 1 |
| Grichy, L | 1 |
| Barreteau, H | 1 |
| Bellivier, F | 1 |
| Lépine, JP | 1 |
| Bloch, V | 1 |
| Melby, K | 1 |
| Gråwe, RW | 1 |
| Aamo, TO | 1 |
| Salvesen, Ø | 1 |
| Spigset, O | 1 |
| Keller, CM | 1 |
| Cornett, EM | 1 |
| Guerin, GF | 1 |
| Goeders, NE | 2 |
| Caputo, F | 1 |
| Skala, K | 1 |
| Mirijello, A | 1 |
| Ferrulli, A | 1 |
| Walter, H | 1 |
| Lesch, O | 1 |
| Addolorato, G | 1 |
| Imbert, B | 1 |
| Marsot, A | 1 |
| Liachenko, N | 1 |
| Simon, N | 1 |
| Nüstedt, V | 1 |
| de Millas, W | 1 |
| Ganzer, F | 1 |
| Haasen, C | 1 |
| Kablinger, AS | 1 |
| Lindner, MA | 1 |
| Casso, S | 1 |
| Hefti, F | 1 |
| DeMuth, G | 1 |
| Fox, BS | 1 |
| McNair, LA | 1 |
| McCarthy, BG | 1 |
| Kampman, KM | 1 |
| Pettinati, H | 1 |
| Volpicelli, J | 1 |
| Kaempf, G | 1 |
| Turk, E | 1 |
| Insua, A | 1 |
| Lipkin, C | 1 |
| Sparkman, T | 1 |
| O'Brien, CP | 2 |
| Gerra, G | 2 |
| Zaimovic, A | 2 |
| Giusti, F | 1 |
| Moi, G | 1 |
| Brewer, C | 1 |
| Khong, E | 1 |
| Sim, MG | 1 |
| Hulse, G | 1 |
| Linnoila, M | 1 |
| Viukari, M | 1 |
| Lamminsivu, U | 1 |
| Auvinen, J | 1 |
| Lapierre, YD | 1 |
| Pecknold, JC | 1 |
| McClure, DJ | 1 |
| Fleuri, D | 1 |
| Chang, H | 1 |
| MacKinnon, GL | 1 |
| Parker, WA | 1 |
| Shader, RI | 1 |
| Greenblatt, DJ | 2 |
| Conell, LJ | 1 |
| Berlin, RM | 1 |
| Gonzalez, JP | 1 |
| McCulloch, AJ | 1 |
| Nicholls, PJ | 1 |
| Sewell, RD | 1 |
| Tekle, A | 1 |
| Ananth, J | 1 |
| Preston, KL | 2 |
| Bigelow, GE | 2 |
| Liebson, IA | 2 |
| Hillbom, ME | 1 |
| Hjelm-Jäger, M | 1 |
| Dobbie, JA | 1 |
| Wilbur, R | 1 |
| Kulik, AV | 1 |
| Moore, C | 1 |
| Walters, L | 1 |
| Nel, P | 1 |
| Martin, JR | 1 |
| Moreau, JL | 1 |
| Jenck, F | 1 |
| Cohen, SI | 1 |
| Wala, EP | 1 |
| Martin, WR | 3 |
| Sloan, JW | 2 |
| Saitz, R | 1 |
| Friedman, LS | 1 |
| Mayo-Smith, MF | 1 |
| Wartenberg, AA | 1 |
| Demaria, PA | 1 |
| Rodgers, C | 1 |
| Braccia, G | 1 |
| Levin, FR | 1 |
| Fischman, MW | 1 |
| Connerney, I | 1 |
| Foltin, RW | 1 |
| McCann, MJ | 1 |
| Miotto, K | 1 |
| Rawson, RA | 1 |
| Huber, A | 1 |
| Shoptaw, S | 1 |
| Ling, W | 1 |
| Wolter-Henseler, DK | 1 |
| Rustichelli, P | 1 |
| Fontanesi, B | 1 |
| Zambelli, U | 1 |
| Timpano, M | 1 |
| Bocchi, C | 1 |
| Delsignore, R | 1 |
| Paetzold, W | 1 |
| Eronat, V | 1 |
| Seifert, J | 1 |
| Holze, I | 1 |
| Emrich, HM | 1 |
| Schneider, U | 1 |
| Reoux, JP | 1 |
| Saxon, AJ | 1 |
| Malte, CA | 1 |
| Baer, JS | 1 |
| Sloan, KL | 1 |
| Daeppen, JB | 1 |
| Gache, P | 1 |
| Landry, U | 1 |
| Sekera, E | 1 |
| Schweizer, V | 1 |
| Gloor, S | 1 |
| Yersin, B | 1 |
| Mendelson, G | 1 |
| Bliding, A | 1 |
| Keeler, MH | 1 |
| Miller, WC | 1 |
| Woo, E | 1 |
| Rane, A | 1 |
| Sundwall, A | 1 |
| Tomson, G | 1 |
| Herman, ZS | 1 |
| Drybański, A | 1 |
| Trzeciak, HI | 1 |
| Sullivan, JT | 1 |
| Sellers, EM | 2 |
| Löscher, W | 1 |
| Hönack, D | 1 |
| Stuppaeck, CH | 1 |
| Pycha, R | 1 |
| Miller, C | 1 |
| Whitworth, AB | 1 |
| Oberbauer, H | 1 |
| Fleischhacker, WW | 1 |
| Dusci, LJ | 1 |
| Good, SM | 1 |
| Hall, RW | 1 |
| Ilett, KF | 1 |
| Ayd, FJ | 1 |
| Ames, D | 1 |
| Malcolm, R | 1 |
| Ballenger, JC | 1 |
| Sturgis, ET | 1 |
| Anton, R | 1 |
| Horwitz, RI | 1 |
| Gottlieb, LD | 2 |
| Kraus, ML | 1 |
| Borg, S | 1 |
| Kvande, H | 1 |
| Valverius, P | 1 |
| Hayashida, M | 1 |
| Alterman, AI | 1 |
| McLellan, AT | 1 |
| Purtill, JJ | 1 |
| Volpicelli, JR | 1 |
| Raphaelson, AH | 1 |
| Hall, CP | 1 |
| Busto, U | 1 |
| Naranjo, CA | 1 |
| Cappell, H | 1 |
| Sanchez-Craig, M | 1 |
| Sykora, K | 1 |
| McNicholas, LF | 2 |
| Wala, E | 1 |
| Hersch, EL | 1 |
| Billings, RF | 1 |
| Bond, WS | 1 |
| Berwish, NJ | 1 |
| Swift, B | 1 |
| Pruitt, TA | 1 |
| Browne, TR | 1 |
| Penry, JK | 1 |
| Gillmer, RE | 1 |
| Mader, R | 1 |
| Schubert, H | 1 |
| Pernhaupt, G | 1 |
| Hanna, SM | 1 |
| Harry, TV | 1 |
| Selig, JW | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Acute and Long-term Effects of Intranasal Oxytocin in Alcohol Withdrawal and Dependence: A Prospective Randomized Parallel Group Placebo-controlled Trial[NCT02903251] | Phase 3 | 40 participants (Actual) | Interventional | 2016-10-31 | Completed | ||
| The Gamma Hydroxybutyric Acid in Alcohol-dependence Treatment Efficacy (GATE) I Trial: a Comparative Study Versus Oxazepam in the Treatment of Alcohol Withdrawal Syndrome[NCT02090504] | Phase 4 | 127 participants (Actual) | Interventional | 2002-02-28 | Completed | ||
| A Phase 1b, Randomized, Double-Blinded, Multiple-Dose, Placebo Controlled, Crossover Study To Evaluate The Safety, Tolerability And Pharmacokinetic Effects Of A Metyrapone And Oxazepam Combination (EMB-001) When Co-Administered With Cocaine[NCT02856854] | Phase 1 | 18 participants (Actual) | Interventional | 2016-07-31 | Completed | ||
| A Phase 2, Randomized, Double-Blind, Placebo-Controlled, Parallel Group, Study to Evaluate the Safety and Efficacy of EMB 001 in Subjects With Moderate-to-Severe Cocaine Use Disorder[NCT04501874] | Phase 2 | 82 participants (Actual) | Interventional | 2020-07-29 | Completed | ||
| Efficacy and Safety of Combination EMB-001 as a Potential Smoking Cessation Treatment[NCT04933916] | Phase 1/Phase 2 | 16 participants (Actual) | Interventional | 2021-06-10 | Terminated (stopped due to Business decision) | ||
| Phenobarbital Versus Ativan for Refractory Alcohol Withdrawal Treatment in the Intensive Care Unit[NCT04156464] | Phase 4 | 142 participants (Anticipated) | Interventional | 2020-07-06 | Recruiting | ||
| Placebo Controlled Trial of Depakote ER in Alcohol Dependent Patients With Mood and/or Anxiety Symptoms[NCT00202514] | Phase 2/Phase 3 | 40 participants | Interventional | 2004-09-30 | Completed | ||
| Prospective Assessment of Valproate on Ethanol Withdrawal[NCT03235531] | Phase 4 | 210 participants (Anticipated) | Interventional | 2017-07-11 | Recruiting | ||
| Acamprosate for Central Nervous System Hyperexcitability and Neuroadaptation in Alcohol Withdrawal[NCT00106106] | Phase 2 | 56 participants (Actual) | Interventional | 2005-03-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
The ratio of glutamate to creatine was determined using magnetic resonance spectroscopy (MRS), a technique that complements magnetic resonance imaging (MRI). MRS is used to determine the concentration of brain metabolites, such as glutamate, in brain tissue. MRS utilizes a magnetic field to look at magnetic nuclei, which absorb and re-emit electromagnetic energy in the presence of the magnetic field. By looking at the peaks in the resultant spectra the structure and concentration of metabolites can be determined. (NCT00106106)
Timeframe: Day 25
| Intervention | Ratio of glutamate to creatine (Mean) |
|---|---|
| Placebo | 1.350375 |
| Acamprosate | 1.166667 |
The ratio of glutamate to creatine was determined using magnetic resonance spectroscopy (MRS), a technique that complements magnetic resonance imaging (MRI). MRS is used to determine the concentration of brain metabolites, such as glutamate, in brain tissue. MRS utilizes a magnetic field to look at magnetic nuclei, which absorb and re-emit electromagnetic energy in the presence of the magnetic field. By looking at the peaks in the resultant spectra the structure and concentration of metabolites can be determined. (NCT00106106)
Timeframe: Day 4
| Intervention | Ratio of glutamate to creatine (Mean) |
|---|---|
| Placebo | 1.256772 |
| Acamprosate | 1.294178 |
6 reviews available for oxazepam and Drug Withdrawal Symptoms
| Article | Year |
|---|---|
Benzodiazepine dependence.
Topics: Anti-Anxiety Agents; Anxiety Disorders; Benzodiazepines; Clinical Protocols; Drug Tolerance; Family | 2004 |
Benzodiazepine withdrawal syndrome: a literature review and evaluation.
Topics: Anti-Anxiety Agents; Chlordiazepoxide; Diazepam; Dose-Response Relationship, Drug; Humans; Lorazepam | 1982 |
The use of benzodiazepines in clinical practice.
Topics: Anti-Anxiety Agents; Chlordiazepoxide; Clorazepate Dipotassium; Diazepam; Humans; Kinetics; Lorazepa | 1981 |
Selection among benzodiazepines for alcohol withdrawal.
Topics: Administration, Oral; Benzodiazepines; Central Nervous System; Chlordiazepoxide; Clorazepate Dipotas | 1977 |
Oxazepam: update 1989.
Topics: Aged; Alcoholism; Alprazolam; Female; Humans; Oxazepam; Seizures; Substance Withdrawal Syndrome; Sub | 1990 |
Benzodiazepines in the treatment of epilepsy. A review.
Topics: Adult; Animals; Anticonvulsants; Chlordiazepoxide; Diazepam; Disease Models, Animal; Eclampsia; Elec | 1973 |
20 trials available for oxazepam and Drug Withdrawal Symptoms
| Article | Year |
|---|---|
Effect of intranasal oxytocin on alcohol withdrawal syndrome: A randomized placebo-controlled double-blind clinical trial.
Topics: Administration, Intranasal; Adult; Alcoholism; Benzodiazepines; Double-Blind Method; Female; Humans; | 2019 |
Sodium oxybate in the treatment of alcohol withdrawal syndrome: a randomized double-blind comparative study versus oxazepam. The GATE 1 trial.
Topics: Adult; Alcoholism; Anxiety; Craving; Double-Blind Method; Female; Humans; Male; Oxazepam; Severity o | 2014 |
Effects of the combination of metyrapone and oxazepam on cocaine craving and cocaine taking: a double-blind, randomized, placebo-controlled pilot study.
Topics: Adult; Cocaine; Cocaine-Related Disorders; Diagnostic and Statistical Manual of Mental Disorders; Do | 2012 |
Effects of the combination of metyrapone and oxazepam on cocaine craving and cocaine taking: a double-blind, randomized, placebo-controlled pilot study.
Topics: Adult; Cocaine; Cocaine-Related Disorders; Diagnostic and Statistical Manual of Mental Disorders; Do | 2012 |
Effects of the combination of metyrapone and oxazepam on cocaine craving and cocaine taking: a double-blind, randomized, placebo-controlled pilot study.
Topics: Adult; Cocaine; Cocaine-Related Disorders; Diagnostic and Statistical Manual of Mental Disorders; Do | 2012 |
Effects of the combination of metyrapone and oxazepam on cocaine craving and cocaine taking: a double-blind, randomized, placebo-controlled pilot study.
Topics: Adult; Cocaine; Cocaine-Related Disorders; Diagnostic and Statistical Manual of Mental Disorders; Do | 2012 |
Effects of the combination of metyrapone and oxazepam on cocaine craving and cocaine taking: a double-blind, randomized, placebo-controlled pilot study.
Topics: Adult; Cocaine; Cocaine-Related Disorders; Diagnostic and Statistical Manual of Mental Disorders; Do | 2012 |
Effects of the combination of metyrapone and oxazepam on cocaine craving and cocaine taking: a double-blind, randomized, placebo-controlled pilot study.
Topics: Adult; Cocaine; Cocaine-Related Disorders; Diagnostic and Statistical Manual of Mental Disorders; Do | 2012 |
Effects of the combination of metyrapone and oxazepam on cocaine craving and cocaine taking: a double-blind, randomized, placebo-controlled pilot study.
Topics: Adult; Cocaine; Cocaine-Related Disorders; Diagnostic and Statistical Manual of Mental Disorders; Do | 2012 |
Effects of the combination of metyrapone and oxazepam on cocaine craving and cocaine taking: a double-blind, randomized, placebo-controlled pilot study.
Topics: Adult; Cocaine; Cocaine-Related Disorders; Diagnostic and Statistical Manual of Mental Disorders; Do | 2012 |
Effects of the combination of metyrapone and oxazepam on cocaine craving and cocaine taking: a double-blind, randomized, placebo-controlled pilot study.
Topics: Adult; Cocaine; Cocaine-Related Disorders; Diagnostic and Statistical Manual of Mental Disorders; Do | 2012 |
Intravenous flumazenil versus oxazepam tapering in the treatment of benzodiazepine withdrawal: a randomized, placebo-controlled study.
Topics: Adult; Anti-Anxiety Agents; Antidotes; Benzodiazepines; Blood Pressure; Cognition Disorders; Diagnos | 2002 |
Efficacy and side effects of lorazepam, oxazepam, and temazepam as sleeping aids in psychogeriatric inpatients.
Topics: Aged; Anti-Anxiety Agents; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Lorazepam; | 1980 |
Benzodiazepine withdrawal effects.
Topics: Anti-Anxiety Agents; Anxiety Disorders; Benzodiazepines; Benzodiazepinones; Drug Administration Sche | 1982 |
[The addiction potential of benzodiazepines. Application of the results of treatment of alcohol withdrawal syndrome].
Topics: Alcohol Withdrawal Delirium; Benzodiazepines; Chlordiazepoxide; Humans; Oxazepam; Psychoses, Alcohol | 1981 |
A protocol to switch high-dose, methadone-maintained subjects to buprenorphine.
Topics: Adult; Anti-Anxiety Agents; Anxiety; Buprenorphine; Clonidine; Cocaine; Drug Administration Schedule | 1997 |
Rapid opiate detoxication in outpatient treatment: relationship with naltrexone compliance.
Topics: Adolescent; Adrenergic alpha-Agonists; Adult; Anti-Inflammatory Agents, Non-Steroidal; Baclofen; Clo | 2000 |
[Detoxification of poly-substance abusers with buprenorphine. Effects on affect, anxiety, and withdrawal symptoms].
Topics: Adult; Affect; Analgesics, Non-Narcotic; Analysis of Variance; Anti-Anxiety Agents; Anxiety; Bupreno | 2000 |
Divalproex sodium in alcohol withdrawal: a randomized double-blind placebo-controlled clinical trial.
Topics: Adolescent; Adult; Aged; Alcoholism; Anticonvulsants; Anxiety; Depression; Double-Blind Method; Etha | 2001 |
Divalproex sodium in alcohol withdrawal: a randomized double-blind placebo-controlled clinical trial.
Topics: Adolescent; Adult; Aged; Alcoholism; Anticonvulsants; Anxiety; Depression; Double-Blind Method; Etha | 2001 |
Divalproex sodium in alcohol withdrawal: a randomized double-blind placebo-controlled clinical trial.
Topics: Adolescent; Adult; Aged; Alcoholism; Anticonvulsants; Anxiety; Depression; Double-Blind Method; Etha | 2001 |
Divalproex sodium in alcohol withdrawal: a randomized double-blind placebo-controlled clinical trial.
Topics: Adolescent; Adult; Aged; Alcoholism; Anticonvulsants; Anxiety; Depression; Double-Blind Method; Etha | 2001 |
Symptom-triggered vs fixed-schedule doses of benzodiazepine for alcohol withdrawal: a randomized treatment trial.
Topics: Alcohol Withdrawal Delirium; Alcohol Withdrawal Seizures; Anti-Anxiety Agents; Double-Blind Method; | 2002 |
Carbamazepine versus oxazepam in the treatment of alcohol withdrawal: a double-blind study.
Topics: Adult; Alcoholism; Carbamazepine; Double-Blind Method; Humans; Middle Aged; Oxazepam; Randomized Con | 1992 |
Double-blind controlled trial comparing carbamazepine to oxazepam treatment of alcohol withdrawal.
Topics: Adult; Alcohol Withdrawal Delirium; Carbamazepine; Clinical Trials as Topic; Double-Blind Method; Et | 1989 |
The efficacy of atenolol in the outpatient management of the alcohol withdrawal syndrome. Results of a randomized clinical trial.
Topics: Adult; Alcoholism; Atenolol; Double-Blind Method; Female; Humans; Male; Middle Aged; Oxazepam; Progn | 1989 |
Clinical conditions and central dopamine metabolism in alcoholics during acute withdrawal under treatment with different pharmacological agents.
Topics: Adult; Aged; Amobarbital; Antipsychotic Agents; Butyrophenones; Double-Blind Method; Ethanol; Homova | 1986 |
The role of beta blockers in alcohol withdrawal syndrome.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Atenolol; Clinical Trials as Topic; Double-Bli | 1988 |
Comparative effectiveness and costs of inpatient and outpatient detoxification of patients with mild-to-moderate alcohol withdrawal syndrome.
Topics: Adult; Ambulatory Care; Ethanol; Follow-Up Studies; Hospitalization; Humans; Male; Outcome and Proce | 1989 |
Withdrawal reaction after long-term therapeutic use of benzodiazepines.
Topics: Adolescent; Adult; Aged; Anxiety; Benzodiazepines; Diazepam; Double-Blind Method; Female; Flurazepam | 1986 |
Benzoctamine and oxazepam in the management of alcohol withdrawal states. Comparison by double-blind trial.
Topics: Adult; Aggression; Alcoholism; Anger; Anthracenes; Anxiety; Clinical Trials as Topic; Drive; Drug Ev | 1973 |
46 other studies available for oxazepam and Drug Withdrawal Symptoms
| Article | Year |
|---|---|
[Acute benzodiazepine withdrawal delirium].
Topics: Alcohol Withdrawal Delirium; Benzodiazepines; Delirium; Diazepam; Humans; Male; Middle Aged; Oxazepa | 2022 |
[Treatment of Alcohol Withdrawal Syndrome with Oxazepam or Clomethiazole - A Naturalistic Observational Study].
Topics: Alcoholism; Chlormethiazole; Female; Germany; Humans; Male; Middle Aged; Oxazepam; Substance Withdra | 2018 |
An observational study of benzodiazepine prescription during inpatient alcohol detoxification for patients with vs. without chronic pretreatment with high-dosage baclofen.
Topics: Administration, Oral; Adult; Alcohol Drinking; Alcoholism; Baclofen; Diazepam; Female; GABA Modulato | 2018 |
Combinations of oxazepam and metyrapone attenuate cocaine and methamphetamine cue reactivity.
Topics: Amphetamine-Related Disorders; Analysis of Variance; Animals; Central Nervous System Stimulants; Coc | 2013 |
Population Pharmacokinetics of High-Dose Oxazepam in Alcohol-Dependent Patients: Is There a Risk of Accumulation?
Topics: Administration, Oral; Adult; Aged; Alcoholism; Body Weight; Drug Monitoring; Ethanol; Female; Half-L | 2016 |
[Ambulant treatment of alcohol withdrawal].
Topics: Alcohol Withdrawal Delirium; Alcoholism; Ambulatory Care; Anticonvulsants; Chlormethiazole; Combined | 2016 |
Oxazepam versus clomethiazol in alcohol withdrawal treatment.
Topics: Adult; Alcoholism; Analysis of Variance; Chlormethiazole; Ethanol; Female; GABA Modulators; Humans; | 2010 |
Concurrent cocaine withdrawal alters alcohol withdrawal symptoms.
Topics: Adolescent; Adult; Alcoholism; Anti-Anxiety Agents; Cocaine; Cocaine-Related Disorders; Ethanol; Fem | 2002 |
Benzodiazepine withdrawal.
Topics: Anti-Anxiety Agents; Anxiety; Diazepam; Drug Tolerance; Humans; Lorazepam; Oxazepam; Sleep Initiatio | 1981 |
Withdrawal after substitution of a short-acting for a long-acting benzodiazepine.
Topics: Anti-Anxiety Agents; Anxiety; Chronic Disease; Delayed-Action Preparations; Diazepam; Flurazepam; Ha | 1983 |
Subacute benzodiazepine treatment: observations on behavioural tolerance and withdrawal.
Topics: Animals; Anti-Anxiety Agents; Behavior, Animal; Conditioning, Psychological; Diazepam; Drinking Beha | 1984 |
Abstinence syndrome from therapeutic doses of oxazepam.
Topics: Adult; Anxiety Disorders; Epilepsy, Tonic-Clonic; Humans; Male; Oxazepam; Substance Withdrawal Syndr | 1983 |
Self-administration of clonidine and oxazepam by methadone detoxification patients.
Topics: Adult; Clonidine; Humans; Male; Methadone; Opioid-Related Disorders; Oxazepam; Psychomotor Performan | 1984 |
Should alcohol withdrawal seizures be treated with anti-epileptic drugs?
Topics: Adult; Aged; Alcohol Withdrawal Delirium; Alcoholism; Anticonvulsants; Carbamazepine; Chlormethiazol | 1984 |
Oxazepam withdrawal syndrome.
Topics: Adolescent; Adult; Confusion; Epilepsy, Tonic-Clonic; Female; Hallucinations; Humans; Middle Aged; O | 1982 |
Oxazepam withdrawal syndrome.
Topics: Adult; Delirium; Epilepsy, Tonic-Clonic; Female; Humans; Male; Middle Aged; Oxazepam; Substance With | 1982 |
Abstinence syndrome from therapeutic doses of oxazepam.
Topics: Adult; Anxiety; Depression; Depressive Disorder; Diazepam; Fasciculation; Fear; Humans; Male; Oxazep | 1983 |
Oxazepam withdrawal syndrome.
Topics: Aged; Humans; Male; Mental Disorders; Myoclonus; Oxazepam; Substance Withdrawal Syndrome | 1982 |
Systematic review of the benzodiazepines. Guidelines for data sheets on diazepam, chlordiazepoxide, medazepam, clorazepate, lorazepam, oxazepam, temazepam, triazolam, nitrazepam, and flurazepam. Committee on the Review of Medicines.
Topics: Benzodiazepines; Chlordiazepoxide; Clorazepate Dipotassium; Diazepam; Flurazepam; Humans; Lorazepam; | 1980 |
Precipitated withdrawal in squirrel monkeys after repeated daily oral administration of alprazolam, diazepam, flunitrazepam or oxazepam.
Topics: Administration, Oral; Alprazolam; Animals; Behavior, Animal; Diazepam; Dose-Response Relationship, D | 1995 |
Alcohol and benzodiazepines generate anxiety, panic and phobias.
Topics: Adult; Aged; Alcohol Drinking; Alcoholism; Anti-Anxiety Agents; Anxiety Disorders; Diazepam; Female; | 1995 |
Pharmacokinetics of nordiazepam in physical dependence and precipitated abstinence in dogs.
Topics: Administration, Oral; Animals; Blood Proteins; Diazepam; Dogs; Female; Flumazenil; Hydrolysis; Injec | 1993 |
Alcohol withdrawal: a nationwide survey of inpatient treatment practices.
Topics: Adrenergic beta-Antagonists; Alcoholism; Barbiturates; Benzodiazepines; Chlordiazepoxide; Clonidine; | 1995 |
Alcohol withdrawal treatment practices.
Topics: Alcoholism; Anti-Anxiety Agents; Ethanol; Humans; Oxazepam; Substance Withdrawal Syndrome; Treatment | 1996 |
Propofol for sedation during rapid opiate detoxification.
Topics: Adult; Clonidine; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Male; Naloxone; Opioid-Re | 1997 |
Outpatient non-opioid detoxification for opioid withdrawal. Who is likely to benefit?
Topics: Adolescent; Adrenergic alpha-Agonists; Adult; Ambulatory Care Facilities; Clonidine; Female; GABA Mo | 1997 |
[Optical hallucinosis during benzodiazepine withdrawal in low-dose dependence].
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Dose-Response Relationship, Drug; Female; Hallucina | 1997 |
Withdrawal reactions after oxazepam.
Topics: Adult; Humans; Male; Oxazepam; Substance Withdrawal Syndrome | 1978 |
The abuse potential of benzodiazepines with special reference to oxazepam.
Topics: Adult; Alcoholism; Anxiety; Benzodiazepines; Female; Humans; Male; Neurotic Disorders; Oxazepam; Sub | 1978 |
Massive benzodiazepine requirements during acute alcohol withdrawal.
Topics: Adult; Alcohol Withdrawal Delirium; Alcoholism; Diazepam; Dose-Response Relationship, Drug; Half-Lif | 1979 |
[Oxazepam withdrawal in the neonatal period].
Topics: Adult; Female; Humans; Infant, Newborn; Infant, Newborn, Diseases; Male; Maternal-Fetal Exchange; Ox | 1979 |
Increased aggression in rats after withdrawal of long term used oxazepam.
Topics: Aggression; Animals; Humans; Male; Oxazepam; Rats; Substance Withdrawal Syndrome | 1976 |
Detoxification for triazolam physical dependence.
Topics: Adult; Alcoholism; Diazepam; Dose-Response Relationship, Drug; Female; Half-Life; Hospitalization; H | 1992 |
Withdrawal precipitation by benzodiazepine receptor antagonists in dogs chronically treated with diazepam or the novel anxiolytic and anticonvulsant beta-carboline abecarnil.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Behavior, Animal; Carbolines; Diazepam; Dogs; Female; | 1992 |
Excretion of diazepam and its metabolites in human milk during withdrawal from combination high dose diazepam and oxazepam.
Topics: Adult; Diazepam; Drug Combinations; Female; Humans; Infant; Milk, Human; Nordazepam; Oxazepam; Subst | 1990 |
Oxazepam and carbamazepine for alcohol withdrawal.
Topics: Carbamazepine; Ethanol; Humans; Oxazepam; Substance Withdrawal Syndrome | 1990 |
Self-administration of clonidine, oxazepam, and hydromorphone by patients undergoing methadone detoxification.
Topics: Adult; Clonidine; Drug Administration Schedule; Humans; Hydromorphone; Male; Methadone; Opioid-Relat | 1985 |
Precipitation of abstinence in nordiazepam- and diazepam-dependent dogs.
Topics: Analysis of Variance; Animals; Diazepam; Dogs; Flumazenil; Nordazepam; Oxazepam; Pyrazoles; Seizures | 1988 |
Acute confusional state with status petit mal as a withdrawal syndrome--and five year follow-up.
Topics: Acute Disease; Cognition Disorders; Confusion; Diazepam; Follow-Up Studies; Humans; Injections, Intr | 1988 |
Severe withdrawal syndrome after substitution of a short-acting benzodiazepine for a long-acting benzodiazepine.
Topics: Diazepam; Female; Half-Life; Humans; Middle Aged; Nordazepam; Oxazepam; Substance Withdrawal Syndrom | 1985 |
N-desmethyldiazepam physical dependence in dogs.
Topics: Analysis of Variance; Animals; Body Weight; Diazepam; Dogs; Drinking; Energy Intake; Female; Lorazep | 1985 |
[Observation of oxazepam dependence].
Topics: Adult; Anxiety Disorders; Humans; Male; Oxazepam; Psychoses, Substance-Induced; Substance Withdrawal | 1972 |
[Oxazepam in the treatment of neurotic disorders as well as in ambulatory detoxication treatment for alcoholics and polytoxicomaniacs].
Topics: Adult; Alcoholism; Ambulatory Care; Austria; Female; Humans; Male; Methods; Neurotic Disorders; Oxaz | 1972 |
A case of oxazepam (serenid D) dependence.
Topics: Adult; Anxiety; Depression; Humans; Male; Oxazepam; Phenelzine; Substance Withdrawal Syndrome; Subst | 1972 |
Oxazepam (Serenid D) dependence.
Topics: Adult; Depression; Humans; Male; Oxazepam; Substance Withdrawal Syndrome; Substance-Related Disorder | 1972 |
A possible oxazepam abstinence syndrome.
Topics: Adult; Antidepressive Agents; Depression; Female; Humans; Oxazepam; Psychotic Disorders; Substance W | 1966 |