oxazepam has been researched along with Body Weight in 18 studies
Oxazepam: A benzodiazepine used in the treatment of anxiety, alcohol withdrawal, and insomnia.
oxazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a hydroxy group at position 3 and phenyl group at position 5.
Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Changes in body weight (BW) in female rats treated for 5 weeks (wk) with weekly subcutaneous implantation of silastic capsules containing different benzodiazepines (BZs): diazepam (DZ) 90, 180, 360 and 540 mg wk-1; nordiazepam (ND) 600 mg wk-1; oxazepam (OX) 600 mg wk-1 and flunitrazepam (FN) 540 mg wk-1 and in male rats exposed to DZ (540 mg wk-1) were evaluated herein." | 3.70 | The effect of chronic benzodiazepines exposure on body weight in rats. ( Jing, X; Sloan, JW; Wala, EP, 1998) |
| "According to the guidelines, benzodiazepines with a short half-life are the reference medication to treat alcohol withdrawal syndrome." | 1.43 | Population Pharmacokinetics of High-Dose Oxazepam in Alcohol-Dependent Patients: Is There a Risk of Accumulation? ( Imbert, B; Liachenko, N; Marsot, A; Simon, N, 2016) |
| "Oxazepam (Serax) is a widely used benzodiazepine anxiolytic agent and a metabolite of other benzodiazepines such as Valium and Librium." | 1.30 | Pharmacodynamic responses of F344 rats to the mouse hepatocarcinogen oxazepam in a 90-day feed study. ( Bucher, JR; Cunningham, ML, 1998) |
| "Oxazepam has been determined to be a potent hepatocarcinogen in mice." | 1.29 | Activity of hepatic drug metabolizing enzymes following oxazepam-dosed feed treatment in B6C3F1 mice. ( Burka, LT; Cunningham, ML; Griffin, RJ, 1995) |
| "A computer model for predicting blood/plasma concentrations of test chemicals in dosed feed and dosed drinking water toxicology studies was developed." | 1.29 | Modeling blood/plasma concentrations in dosed feed and dosed drinking water toxicology studies. ( Yuan, J, 1993) |
| " The elimination half-life increased to 1." | 1.28 | Influence of a very low calorie diet on the clearance of oxazepam and antipyrine in man. ( Andreasen, F; Dragsted, J; Døssing, M; Loft, S; Sonne, J, 1989) |
| "Diazepam was more effective than oxazepam and its effect was proportionate to dose." | 1.27 | Tumor-promoting activity of benzodiazepine tranquilizers, diazepam and oxazepam, in mouse liver. ( Diwan, BA; Rice, JM; Ward, JM, 1986) |
| "Dogs, surgically implanted with a chronic gastric fistula, were chronically dosed with N-desmethyldiazepam (32 mg/kg/day) in four divided doses to attain N-desmethyldiazepam plasma levels comparable to those observed in dogs dependent on diazepam (60 mg/kg/day)." | 1.27 | N-desmethyldiazepam physical dependence in dogs. ( Martin, WR; McNicholas, LF; Pruitt, TA, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (50.00) | 18.7374 |
| 1990's | 7 (38.89) | 18.2507 |
| 2000's | 1 (5.56) | 29.6817 |
| 2010's | 1 (5.56) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Imbert, B | 1 |
| Marsot, A | 1 |
| Liachenko, N | 1 |
| Simon, N | 1 |
| Parkinson, A | 1 |
| Leonard, N | 1 |
| Draper, A | 1 |
| Ogilvie, BW | 1 |
| Koczkas, S | 1 |
| Holmberg, G | 1 |
| Wedin, L | 1 |
| Griffin, RJ | 1 |
| Burka, LT | 1 |
| Cunningham, ML | 2 |
| Yuan, J | 1 |
| Bucher, JR | 2 |
| Haseman, JK | 1 |
| Herbert, RA | 1 |
| Hejtmancik, M | 1 |
| Ryan, MJ | 1 |
| Jing, X | 1 |
| Wala, EP | 1 |
| Sloan, JW | 1 |
| Laegreid, L | 1 |
| Hagberg, G | 1 |
| Lundberg, A | 1 |
| Hamberg, O | 1 |
| Ovesen, L | 1 |
| Dorfeldt, A | 1 |
| Loft, S | 2 |
| Sonne, J | 2 |
| Dragsted, J | 1 |
| Døssing, M | 1 |
| Andreasen, F | 1 |
| Loew, F | 1 |
| Pawlak, C | 1 |
| Benaroyo, L | 1 |
| Junod, JP | 1 |
| Wissel, PS | 1 |
| Denke, M | 1 |
| Inturrisi, CE | 1 |
| Diwan, BA | 1 |
| Rice, JM | 1 |
| Ward, JM | 1 |
| McNicholas, LF | 1 |
| Martin, WR | 1 |
| Pruitt, TA | 1 |
| Opitz, K | 1 |
| Akinlaja, A | 1 |
| Schwartz, MA | 1 |
| Carbone, JJ | 1 |
| Murray, WJ | 1 |
| Bechtoldt, AA | 1 |
| Berman, L | 1 |
3 trials available for oxazepam and Body Weight
| Article | Year |
|---|---|
The effect of dietary energy and protein deficiency on drug metabolism.
Topics: Adult; Antipyrine; Biotransformation; Body Weight; Diet; Energy Metabolism; Glucuronates; Humans; Ma | 1990 |
Comparison of midazolam and oxazepam as hypnotics in elderly hospitalized patients. A double-blind clinical trial.
Topics: Aged; Aged, 80 and over; Aging; Body Weight; Clinical Trials as Topic; Double-Blind Method; Dreams; | 1988 |
Efficacy of oral psychosedative drugs for preanesthetic medication.
Topics: Adult; Age Factors; Anxiety; Body Weight; Diazepam; Ethchlorvynol; Female; Humans; Hydroxyzine; Hypn | 1968 |
15 other studies available for oxazepam and Body Weight
| Article | Year |
|---|---|
Population Pharmacokinetics of High-Dose Oxazepam in Alcohol-Dependent Patients: Is There a Risk of Accumulation?
Topics: Administration, Oral; Adult; Aged; Alcoholism; Body Weight; Drug Monitoring; Ethanol; Female; Half-L | 2016 |
On the mechanism of hepatocarcinogenesis of benzodiazepines: evidence that diazepam and oxazepam are CYP2B inducers in rats, and both CYP2B and CYP4A inducers in mice.
Topics: Animals; Benzodiazepines; Blotting, Western; Body Weight; Carcinogens; Cytochrome P-450 CYP1A1; Cyto | 2006 |
A pilot study of the effect of the 5-HT-uptake inhibitor, zimelidine, on phobic anxiety.
Topics: Adolescent; Adult; Anxiety; Body Weight; Brompheniramine; Electrocardiography; Humans; Middle Aged; | 1981 |
Activity of hepatic drug metabolizing enzymes following oxazepam-dosed feed treatment in B6C3F1 mice.
Topics: Aminopyrine N-Demethylase; Analysis of Variance; Aniline Hydroxylase; Animals; Body Weight; Cytochro | 1995 |
Modeling blood/plasma concentrations in dosed feed and dosed drinking water toxicology studies.
Topics: Animals; Body Weight; Computer Simulation; Eating; Female; Half-Life; Male; Mice; Oxazepam; Pentachl | 1993 |
Pharmacodynamic responses of F344 rats to the mouse hepatocarcinogen oxazepam in a 90-day feed study.
Topics: Animals; Body Weight; Carcinogens; Cell Division; Dose-Response Relationship, Drug; Liver; Male; Org | 1998 |
Toxicity and carcinogenicity studies of oxazepam in the Fischer 344 rat.
Topics: Adenoma; Animals; Anti-Anxiety Agents; Body Weight; Carcinogenicity Tests; Digestive System; Female; | 1998 |
The effect of chronic benzodiazepines exposure on body weight in rats.
Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Body Weight; Diazepam; Dose-Response Relationshi | 1998 |
Neurodevelopment in late infancy after prenatal exposure to benzodiazepines--a prospective study.
Topics: Abnormalities, Drug-Induced; Anti-Anxiety Agents; Arousal; Body Height; Body Weight; Cephalometry; D | 1992 |
Influence of a very low calorie diet on the clearance of oxazepam and antipyrine in man.
Topics: Adult; Antipyrine; Body Weight; Chromatography, High Pressure Liquid; Diet, Reducing; Energy Intake; | 1989 |
A comparison of the effects of a macrobiotic diet and a Western diet on drug metabolism and plasma lipids in man.
Topics: Adult; Antipyrine; Body Weight; Cholesterol; Diet; Humans; Lipids; Lipoproteins, HDL; Lipoproteins, | 1987 |
Tumor-promoting activity of benzodiazepine tranquilizers, diazepam and oxazepam, in mouse liver.
Topics: Aminopyrine N-Demethylase; Animals; Body Weight; Cocarcinogenesis; Cytochrome P-450 Enzyme System; D | 1986 |
N-desmethyldiazepam physical dependence in dogs.
Topics: Analysis of Variance; Animals; Body Weight; Diazepam; Dogs; Drinking; Energy Intake; Female; Lorazep | 1985 |
[On the influencing of food intake by psychotropic drugs].
Topics: Amitriptyline; Animals; Behavior, Animal; Body Weight; Central Nervous System; Central Nervous Syste | 1966 |
Metabolism of 14C-medazepam hydrochloride in dog, rat and man.
Topics: Adipose Tissue; Administration, Oral; Animals; Benzazepines; Biotransformation; Body Weight; Brain C | 1970 |