oxazepam has been researched along with Alcohol Withdrawal Associated Autonomic Hyperactivity in 14 studies
Oxazepam: A benzodiazepine used in the treatment of anxiety, alcohol withdrawal, and insomnia.
oxazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a hydroxy group at position 3 and phenyl group at position 5.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Seizures and delirium tremens were recorded among 292 randomly selected patients admitted to an in-patient alcoholism program." | 1.27 | Should alcohol withdrawal seizures be treated with anti-epileptic drugs? ( Hillbom, ME; Hjelm-Jäger, M, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (35.71) | 18.7374 |
| 1990's | 5 (35.71) | 18.2507 |
| 2000's | 2 (14.29) | 29.6817 |
| 2010's | 1 (7.14) | 24.3611 |
| 2020's | 1 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Mäkinen, VN | 1 |
| Hansen, KB | 1 |
| Knudsen, ST | 1 |
| Nüstedt, V | 1 |
| Hillbom, ME | 1 |
| Hjelm-Jäger, M | 1 |
| Walters, L | 1 |
| Nel, P | 1 |
| Mayo-Smith, MF | 1 |
| Bernard, D | 1 |
| Prater, CD | 1 |
| Miller, KE | 1 |
| Zylstra, RG | 1 |
| Reoux, JP | 1 |
| Miller, K | 1 |
| Daeppen, JB | 1 |
| Gache, P | 1 |
| Landry, U | 1 |
| Sekera, E | 1 |
| Schweizer, V | 1 |
| Gloor, S | 1 |
| Yersin, B | 1 |
| Woo, E | 1 |
| Greenblatt, DJ | 1 |
| Balldin, J | 1 |
| Berggren, U | 1 |
| Engel, J | 1 |
| Lindstedt, G | 1 |
| Sundkler, A | 1 |
| Wålinder, J | 1 |
| Gallant, DM | 2 |
| Sullivan, JT | 1 |
| Swift, RM | 1 |
| Lewis, DC | 1 |
| Malcolm, R | 1 |
| Ballenger, JC | 1 |
| Sturgis, ET | 1 |
| Anton, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Acamprosate for Central Nervous System Hyperexcitability and Neuroadaptation in Alcohol Withdrawal[NCT00106106] | Phase 2 | 56 participants (Actual) | Interventional | 2005-03-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
The ratio of glutamate to creatine was determined using magnetic resonance spectroscopy (MRS), a technique that complements magnetic resonance imaging (MRI). MRS is used to determine the concentration of brain metabolites, such as glutamate, in brain tissue. MRS utilizes a magnetic field to look at magnetic nuclei, which absorb and re-emit electromagnetic energy in the presence of the magnetic field. By looking at the peaks in the resultant spectra the structure and concentration of metabolites can be determined. (NCT00106106)
Timeframe: Day 25
| Intervention | Ratio of glutamate to creatine (Mean) |
|---|---|
| Placebo | 1.350375 |
| Acamprosate | 1.166667 |
The ratio of glutamate to creatine was determined using magnetic resonance spectroscopy (MRS), a technique that complements magnetic resonance imaging (MRI). MRS is used to determine the concentration of brain metabolites, such as glutamate, in brain tissue. MRS utilizes a magnetic field to look at magnetic nuclei, which absorb and re-emit electromagnetic energy in the presence of the magnetic field. By looking at the peaks in the resultant spectra the structure and concentration of metabolites can be determined. (NCT00106106)
Timeframe: Day 4
| Intervention | Ratio of glutamate to creatine (Mean) |
|---|---|
| Placebo | 1.256772 |
| Acamprosate | 1.294178 |
1 review available for oxazepam and Alcohol Withdrawal Associated Autonomic Hyperactivity
| Article | Year |
|---|---|
Outpatient detoxification of the addicted or alcoholic patient.
Topics: Alcohol Withdrawal Delirium; Alcoholic Intoxication; Ambulatory Care; Anti-Anxiety Agents; Chlordiaz | 1999 |
6 trials available for oxazepam and Alcohol Withdrawal Associated Autonomic Hyperactivity
| Article | Year |
|---|---|
[The addiction potential of benzodiazepines. Application of the results of treatment of alcohol withdrawal syndrome].
Topics: Alcohol Withdrawal Delirium; Benzodiazepines; Chlordiazepoxide; Humans; Oxazepam; Psychoses, Alcohol | 1981 |
Symptom-triggered vs fixed-schedule doses of benzodiazepine for alcohol withdrawal: a randomized treatment trial.
Topics: Alcohol Withdrawal Delirium; Alcohol Withdrawal Seizures; Anti-Anxiety Agents; Double-Blind Method; | 2002 |
Alpha-2-adrenoceptor sensitivity in early alcohol withdrawal.
Topics: Adult; Alcohol Withdrawal Delirium; Blood Pressure; Chlormethiazole; Chlorprothixene; Clonidine; Dos | 1992 |
One more look at carbamazepine in the treatment of alcohol withdrawal.
Topics: Adolescent; Adult; Aged; Alcohol Withdrawal Delirium; Alcoholism; Carbamazepine; Double-Blind Method | 1992 |
Double-blind controlled trial comparing carbamazepine to oxazepam treatment of alcohol withdrawal.
Topics: Adult; Alcohol Withdrawal Delirium; Carbamazepine; Clinical Trials as Topic; Double-Blind Method; Et | 1989 |
Improvements in treatment of alcohol withdrawal syndromes.
Topics: Alcohol Withdrawal Delirium; Carbamazepine; Double-Blind Method; Humans; Oxazepam; Psychoses, Alcoho | 1989 |
7 other studies available for oxazepam and Alcohol Withdrawal Associated Autonomic Hyperactivity
| Article | Year |
|---|---|
[Acute benzodiazepine withdrawal delirium].
Topics: Alcohol Withdrawal Delirium; Benzodiazepines; Delirium; Diazepam; Humans; Male; Middle Aged; Oxazepa | 2022 |
[Ambulant treatment of alcohol withdrawal].
Topics: Alcohol Withdrawal Delirium; Alcoholism; Ambulatory Care; Anticonvulsants; Chlormethiazole; Combined | 2016 |
Should alcohol withdrawal seizures be treated with anti-epileptic drugs?
Topics: Adult; Aged; Alcohol Withdrawal Delirium; Alcoholism; Anticonvulsants; Carbamazepine; Chlormethiazol | 1984 |
Late-onset seizures in alcohol withdrawal.
Topics: Adult; Aged; Alcohol Withdrawal Delirium; Alcoholism; Anti-Anxiety Agents; Diagnosis, Differential; | 1995 |
Routine hospital alcohol detoxification practice compared to symptom triggered management with an Objective Withdrawal Scale (CIWA-Ar).
Topics: Adult; Aged; Alcohol Withdrawal Delirium; Alcoholism; Chlordiazepoxide; Female; Hospitalization; Hos | 2000 |
Massive benzodiazepine requirements during acute alcohol withdrawal.
Topics: Adult; Alcohol Withdrawal Delirium; Alcoholism; Diazepam; Dose-Response Relationship, Drug; Half-Lif | 1979 |
Benzodiazepine requirements during alcohol withdrawal syndrome: clinical implications of using a standardized withdrawal scale.
Topics: Administration, Oral; Adult; Alcohol Withdrawal Delirium; Anti-Anxiety Agents; Chlordiazepoxide; Dia | 1991 |