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oxazepam and Aggression

oxazepam has been researched along with Aggression in 25 studies

Oxazepam: A benzodiazepine used in the treatment of anxiety, alcohol withdrawal, and insomnia.
oxazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a hydroxy group at position 3 and phenyl group at position 5.

Aggression: Behavior which may be manifested by destructive and attacking action which is verbal or physical, by covert attitudes of hostility or by obstructionism.

Research Excerpts

ExcerptRelevanceReference
"Two doses of two very similar benzodiazepines (oxazepam 15 and 30 mg: lorazepam 1 and 2 mg) and placebo were compared 4 h post-administration on a competitive reaction time task designed to measure behavioural aggression."5.06Differential effects of oxazepam and lorazepam on aggressive responding. ( Bond, A; Lader, M, 1988)
"Oxazepam has a short half-life and inactive metabolites and therefore differs from most other benzodiazepines."3.74The clinical pharmacology of oxazepam. ( Lader, MH, 1978)
" Despite its lesser tendency to induce aggression in humans, Oxazepam is as potent as Chlordiazepoxide for inducing killing by rats."3.67Oxazepam induced mouse killing by rats. ( Lamon, S; Leaf, RC; Wnek, DJ, 1984)
"Oxazepam was also superior to the latter on 1 subscale of tests used to measure hostility."2.65Benzodiazepines in the treatment of aggressive patients. ( Lion, JR, 1979)

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-199023 (92.00)18.7374
1990's2 (8.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Leaf, RC1
Wnek, DJ1
Lamon, S1
Harry, TV1
Weisman, AM1
Berman, ME1
Taylor, SP1
Solomon, K1
Azcarate, CL2
Scrollini, F1
Caliari, S1
Romano, A1
Torchio, P1
Lader, MH1
Garattini, S2
Lion, JR2
Herman, ZS1
Drybański, A1
Trzeciak, HI1
Koepke, HH1
Krsiak, M1
Sulcova, A1
Bond, A1
Lader, M1
Pellis, SM1
O'Brien, DP1
Pellis, VC1
Teitelbaum, P1
Wolgin, DL1
Kennedy, S1
Podvalová, I1
Dlabac, A1
Valzelli, L1
Fox, KA1
Guerriero, FJ1
Zanghi, DC1
Prokudin, VN1
Gillmer, RE1
Guaitani, A1
Marcucci, F1
Christmas, AJ1
Maxwell, DR1
Bauen, A1
Possanza, GJ1
Yen, HC1
Katz, MH1
Krop, S1
Nievoll, A1
Danielczyk, W1

Reviews

5 reviews available for oxazepam and Aggression

ArticleYear
Benzodiazepines and neurotic anxiety. Critique.
    New York state journal of medicine, 1976, Volume: 76, Issue:13

    Topics: Aggression; Animals; Anti-Anxiety Agents; Anxiety; Behavior; Behavior, Animal; Chemical Phenomena; C

1976
Minor tranquilizers in the treatment of aggression.
    The Journal of nervous and mental disease, 1975, Volume: 160, Issue:2-1

    Topics: Aggression; Animals; Anti-Anxiety Agents; Anxiety; Chlordiazepoxide; Depression; Diazepam; Epilepsy;

1975
The clinical pharmacology of oxazepam.
    Acta psychiatrica Scandinavica. Supplementum, 1978, Issue:274

    Topics: Aggression; Anxiety; Chlordiazepoxide; Clinical Trials as Topic; Drug Evaluation; Humans; Oxazepam;

1978
Biochemical and pharmacological properties of oxazepam.
    Acta psychiatrica Scandinavica. Supplementum, 1978, Issue:274

    Topics: Acetylcholine; Aggression; Animals; Anticonvulsants; Behavior, Animal; Brain; Chemical Phenomena; Ch

1978
[Features of the clinical effect of benzodiazepine derivatives (according to the findings of comparative studies). Review of the literature].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1973, Volume: 73, Issue:2

    Topics: Adjustment Disorders; Aggression; Animals; Antisocial Personality Disorder; Barbiturates; Benzazepin

1973

Trials

6 trials available for oxazepam and Aggression

ArticleYear
Effects of clorazepate, diazepam, and oxazepam on a laboratory measurement of aggression in men.
    International clinical psychopharmacology, 1998, Volume: 13, Issue:4

    Topics: Adult; Aggression; Anti-Anxiety Agents; Clorazepate Dipotassium; Diazepam; Double-Blind Method; Huma

1998
Benzodiazepines and neurotic anxiety. Critique.
    New York state journal of medicine, 1976, Volume: 76, Issue:13

    Topics: Aggression; Animals; Anti-Anxiety Agents; Anxiety; Behavior; Behavior, Animal; Chemical Phenomena; C

1976
The clinical pharmacology of oxazepam.
    Acta psychiatrica Scandinavica. Supplementum, 1978, Issue:274

    Topics: Aggression; Anxiety; Chlordiazepoxide; Clinical Trials as Topic; Drug Evaluation; Humans; Oxazepam;

1978
Benzodiazepines in the treatment of aggressive patients.
    The Journal of clinical psychiatry, 1979, Volume: 40, Issue:2

    Topics: Adult; Aggression; Antisocial Personality Disorder; Chlordiazepoxide; Dose-Response Relationship, Dr

1979
Differential effects of oxazepam and lorazepam on aggressive responding.
    Psychopharmacology, 1988, Volume: 95, Issue:3

    Topics: Adult; Aggression; Anxiety; Emotions; Female; Humans; Lorazepam; Male; Middle Aged; Oxazepam; Reacti

1988
Benzoctamine and oxazepam in the management of alcohol withdrawal states. Comparison by double-blind trial.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1973, Dec-01, Volume: 47, Issue:47

    Topics: Adult; Aggression; Alcoholism; Anger; Anthracenes; Anxiety; Clinical Trials as Topic; Drive; Drug Ev

1973

Other Studies

16 other studies available for oxazepam and Aggression

ArticleYear
Oxazepam induced mouse killing by rats.
    Pharmacology, biochemistry, and behavior, 1984, Volume: 20, Issue:2

    Topics: Aggression; Animals; Chlordiazepoxide; Chlorpromazine; Dose-Response Relationship, Drug; Humans; Mal

1984
Oxazepam--drug of choice for aggressive patients?
    British medical journal (Clinical research ed.), 1981, Jan-17, Volume: 282, Issue:6259

    Topics: Aggression; Humans; Oxazepam

1981
Toxicological and pharmacological investigations of pinazepam (7-chloro-1-propargyl-5-phenyl-3H-1,4-benzodiazepin-2-one): a new psychotherapeutic agent.
    Arzneimittel-Forschung, 1975, Volume: 25, Issue:6

    Topics: Abnormalities, Drug-Induced; Aggression; Analgesia; Animals; Anti-Anxiety Agents; Blood Pressure; Ca

1975
Increased aggression in rats after withdrawal of long term used oxazepam.
    Experientia, 1976, Oct-15, Volume: 32, Issue:10

    Topics: Aggression; Animals; Humans; Male; Oxazepam; Rats; Substance Withdrawal Syndrome

1976
"Paradoxical rage reactions" during psychotropic medication.
    Diseases of the nervous system, 1975, Volume: 36, Issue:10

    Topics: Adult; Aggression; Anger; Child; Clorazepate Dipotassium; Diazepam; Ethanol; Female; Humans; Individ

1975
Differential effects of six structurally related benzodiazepines on some ethological measures of timidity, aggression and locomotion in mice.
    Psychopharmacology, 1990, Volume: 101, Issue:3

    Topics: Aggression; Alprazolam; Animals; Anti-Anxiety Agents; Behavior, Animal; Clonazepam; Lorazepam; Male;

1990
Escalation of feline predation along a gradient from avoidance through "play" to killing.
    Behavioral neuroscience, 1988, Volume: 102, Issue:5

    Topics: Aggression; Agonistic Behavior; Animals; Appetitive Behavior; Brain Mapping; Cats; Diazepam; Female;

1988
Aggressive behavior of rats induced by mesorgydine (Lysenyl Spofa).
    Activitas nervosa superior, 1970, Jan-12, Volume: 12, Issue:1

    Topics: Aggression; Animals; Chlordiazepoxide; Chlorpromazine; Dibenzothiepins; Drug Antagonism; Histamine H

1970
Further aspects of the exploratory behaviour in aggressive mice.
    Psychopharmacologia, 1971, Volume: 19, Issue:1

    Topics: Aggression; Animals; Appetite Depressants; Behavior, Animal; Benzazepines; Exploratory Behavior; Fen

1971
Oxazepam, prazepam, and aggression in mice.
    Pharmacological research communications, 1974, Volume: 6, Issue:3

    Topics: Aggression; Animals; Behavior, Animal; Diet; Humans; Male; Mice; Oxazepam; Prazepam; Stimulation, Ch

1974
Increased aggression and toxicity in grouped male mice treated with tranquilizing benzodiazepines.
    Psychopharmacologia, 1971, Volume: 19, Issue:3

    Topics: Aggression; Animals; Behavior, Animal; Diazepam; Dibenzazepines; Female; Humans; Male; Methylation;

1971
A comparison of the effects of some benzodiazepines and other drugs on aggressive and exploratory behaviour in mice and rats.
    Neuropharmacology, 1970, Volume: 9, Issue:1

    Topics: Aggression; Animals; Chlordiazepoxide; Diazepam; Electroshock; Exploratory Behavior; Humans; Locomot

1970
The mink as a psychopharmacological model.
    Archives internationales de pharmacodynamie et de therapie, 1970, Volume: 186, Issue:1

    Topics: Aggression; Animals; Chlordiazepoxide; Chlorpromazine; Diazepam; Humans; Male; Meprobamate; Mink; Mo

1970
Effects of various drugs on 3,4-dihydroxyphenylalanine (DL-DOPA)-induced excitation (agressive behavior) in mice.
    Toxicology and applied pharmacology, 1970, Volume: 17, Issue:3

    Topics: Aggression; Animals; Antidepressive Agents; Autonomic Agents; Behavior, Animal; Bretylium Compounds;

1970
[Therapeutic experiences with oxazepam--a derivative of the benzodiazepine series--in child and adolescent psychiatry].
    Wiener klinische Wochenschrift, 1971, Apr-09, Volume: 83, Issue:14

    Topics: Adolescent; Adolescent Psychiatry; Adult; Aggression; Amitriptyline; Anticonvulsants; Brain Damage,

1971
[Objective methods in testing of a new tranquilizer in geriatrics].
    Die Medizinische Welt, 1968, Mar-02, Volume: 9

    Topics: Affective Symptoms; Aged; Aggression; Chlordiazepoxide; Electroencephalography; Electromyography; Fe

1968