oxatomide has been researched along with Rhinitis, Allergic, Seasonal in 15 studies
oxatomide: structure; an anti-allergic & an anti-asthmatic
oxatomide : A member of the class of benzimidazoles that is 1,3-dihydro-2H-benzimidazol-2-one substituted by a 3-[4-(diphenylmethyl)piperazin-1-yl]propyl group at position 1. It is an anti-allergic drug.
Rhinitis, Allergic, Seasonal: Allergic rhinitis that occurs at the same time every year. It is characterized by acute CONJUNCTIVITIS with lacrimation and ITCHING, and regarded as an allergic condition triggered by specific ALLERGENS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The new antiallergic drug oxatomide was evaluated in 40 schoolchildren suffering from severe allergic seasonal rhinoconjunctivitis." | 9.05 | Oxatomide in seasonal rhinoconjunctivitis. ( Björkstén, B; Möller, C, 1980) |
| " The effects of ingested oxatomide (30 mg/capsule) were compared with those of chlorpheniramine (5 mg/capsule) in a double-blind non-crossover study in two groups of twenty-five subjects with ragweed pollen-induced hay fever during the pollen season." | 9.05 | Effects of oxatomide compared with chlorpheniramine in allergic rhinoconjunctivitis. ( Cartier, A; Dolovich, J; Frith, PA; Hargreave, FE; Juniper, EF; Trebilcock, AL, 1981) |
| "Ninety-one hay fever patients received either 0." | 6.65 | A double-blind comparison of oxatomide (R 35 443) and diphenhydramine in the treatment of hay fever. ( Cordier, R; De Proost, W; van der Bijl, WJ; van Dishoeck, EA; Vannieuwenhuyse, E, 1980) |
| "The new antiallergic drug oxatomide was evaluated in 40 schoolchildren suffering from severe allergic seasonal rhinoconjunctivitis." | 5.05 | Oxatomide in seasonal rhinoconjunctivitis. ( Björkstén, B; Möller, C, 1980) |
| " The effects of ingested oxatomide (30 mg/capsule) were compared with those of chlorpheniramine (5 mg/capsule) in a double-blind non-crossover study in two groups of twenty-five subjects with ragweed pollen-induced hay fever during the pollen season." | 5.05 | Effects of oxatomide compared with chlorpheniramine in allergic rhinoconjunctivitis. ( Cartier, A; Dolovich, J; Frith, PA; Hargreave, FE; Juniper, EF; Trebilcock, AL, 1981) |
| "Ninety-one hay fever patients received either 0." | 2.65 | A double-blind comparison of oxatomide (R 35 443) and diphenhydramine in the treatment of hay fever. ( Cordier, R; De Proost, W; van der Bijl, WJ; van Dishoeck, EA; Vannieuwenhuyse, E, 1980) |
| "CD14+ cells prepared from patients with pollinosis to Japanese cedar pollen were stimulated with specific allergen extracted from Japanese cedar pollen (Cry j 1) in the presence of azelastine (AZE), ketotifen (KET), fexofenadine (FEX) and oxatomide (OXA) for 6 days." | 1.37 | Effect of histamine H1 receptor antagonists on TARC/CCL17 and MDC/CCL22 production from CD14+ cells induced by antigenic stimulation in vitro. ( Asano, K; Furuta, A; Hirano, K; Shoji, N; Suzaki, H, 2011) |
| " Second-generation antihistamines have become increasingly popular because of their comparable efficacy and lower incidence of adverse effects relative to their first-generation counterparts, and the safety and efficacy of this drug class are established in the adult population." | 1.35 | Treatment of allergic rhinitis in infants and children: efficacy and safety of second-generation antihistamines and the leukotriene receptor antagonist montelukast. ( Moeller, ML; Nahata, MC; Phan, H, 2009) |
| "Treatment with oxatomide, an anti-histamine and anti-allergic drug, significantly improved symptom scores, but did not alleviate them completely." | 1.29 | Laser high performance liquid chromatography determination of prostaglandins in nasal lavage fluid in allergic rhinitis. ( Ozawa, T; Sugimoto, M; Sugiyama, S; Yanagita, N, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (60.00) | 18.7374 |
| 1990's | 4 (26.67) | 18.2507 |
| 2000's | 1 (6.67) | 29.6817 |
| 2010's | 1 (6.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Phan, H | 1 |
| Moeller, ML | 1 |
| Nahata, MC | 1 |
| Shoji, N | 1 |
| Asano, K | 1 |
| Furuta, A | 1 |
| Hirano, K | 1 |
| Suzaki, H | 1 |
| Wood, SF | 1 |
| Barber, JH | 1 |
| D'Souza, MF | 1 |
| Emanuel, MB | 1 |
| Gregg, J | 1 |
| Charlton, J | 1 |
| Goldschmidt, J | 1 |
| van der Bijl, WJ | 1 |
| Cordier, R | 1 |
| van Dishoeck, EA | 1 |
| De Proost, W | 1 |
| Vannieuwenhuyse, E | 2 |
| Möller, C | 1 |
| Björkstén, B | 1 |
| Juniper, EF | 1 |
| Cartier, A | 1 |
| Trebilcock, AL | 1 |
| Frith, PA | 1 |
| Dolovich, J | 1 |
| Hargreave, FE | 1 |
| De Cree, J | 1 |
| Hörig, C | 1 |
| Verhaegen, H | 1 |
| Sugimoto, M | 1 |
| Sugiyama, S | 1 |
| Yanagita, N | 1 |
| Ozawa, T | 1 |
| Kaise, T | 1 |
| Akamatsu, Y | 1 |
| Ohmori, K | 1 |
| de Beule, R | 1 |
| Callier, J | 1 |
| Verstraete, W | 1 |
| Degreef, F | 1 |
| Gregoire, M | 1 |
| Robience, Y | 1 |
| Stevens, W | 1 |
| Libert, P | 1 |
| Antmann, I | 1 |
| Bittera, I | 1 |
| Kadocsa, E | 1 |
| Gyurkovits, K | 1 |
| Mühlbacher, S | 1 |
| Zelen, B | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effectiveness of Montelukast Versus Intranasal Fluticasone Propionate in the Management of Allergic Rhinitis Among Children 02 to 05 Years of Age[NCT04957927] | Phase 4 | 60 participants (Anticipated) | Interventional | 2020-12-12 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for oxatomide and Rhinitis, Allergic, Seasonal
| Article | Year |
|---|---|
[Comparative study of ketotiphen and oxatomide (repeated skin- and nasal provocation)].
Topics: Adolescent; Child; Drug Evaluation; Female; Histamine H1 Antagonists; Humans; Ketotifen; Male; Nasal | 1990 |
7 trials available for oxatomide and Rhinitis, Allergic, Seasonal
| Article | Year |
|---|---|
Oxatomide in the management of hay fever--a placebo-controlled double-blind study in general practice.
Topics: Administration, Oral; Adolescent; Adult; Child; Clinical Trials as Topic; Double-Blind Method; Femal | 1981 |
A method for evaluating therapy for hay fever. A comparison of four treatments.
Topics: Adult; Airway Resistance; Beclomethasone; Clinical Trials as Topic; Cromolyn Sodium; Female; Forced | 1983 |
A double-blind comparison of oxatomide (R 35 443) and diphenhydramine in the treatment of hay fever.
Topics: Adolescent; Adult; Child; Clinical Trials as Topic; Diphenhydramine; Double-Blind Method; Fatigue; F | 1980 |
Oxatomide in seasonal rhinoconjunctivitis.
Topics: Adolescent; Child; Child, Preschool; Cinnarizine; Clinical Trials as Topic; Conjunctivitis; Double-B | 1980 |
Effects of oxatomide compared with chlorpheniramine in allergic rhinoconjunctivitis.
Topics: Adolescent; Adult; Chlorpheniramine; Conjunctivitis; Humans; Middle Aged; Piperazines; Pollen; Rhini | 1981 |
Double-blind placebo-controlled clinical evaluation of oxatimide (R 35443). A novel potent anti-allergic drug in the treatment of hay fever.
Topics: Administration, Oral; Adolescent; Adult; Aged; Child; Child, Preschool; Clinical Trials as Topic; Di | 1977 |
Prospective study with Tinset tablet.
Topics: Administration, Oral; Female; Histamine H1 Antagonists; Humans; Male; Piperazines; Prospective Studi | 1992 |
7 other studies available for oxatomide and Rhinitis, Allergic, Seasonal
| Article | Year |
|---|---|
Treatment of allergic rhinitis in infants and children: efficacy and safety of second-generation antihistamines and the leukotriene receptor antagonist montelukast.
Topics: Acetates; Administration, Oral; Adult; Anti-Allergic Agents; Anti-Asthmatic Agents; Astemizole; Ceti | 2009 |
Effect of histamine H1 receptor antagonists on TARC/CCL17 and MDC/CCL22 production from CD14+ cells induced by antigenic stimulation in vitro.
Topics: Adult; Antigens, Plant; Cell Proliferation; Chemokine CCL17; Chemokine CCL22; Chlorpheniramine; Extr | 2011 |
Oxatomide in the treatment of various allergic diseases.
Topics: Adolescent; Adult; Aged; Asthma; Child; Child, Preschool; Female; Gastrointestinal Diseases; Humans; | 1980 |
Laser high performance liquid chromatography determination of prostaglandins in nasal lavage fluid in allergic rhinitis.
Topics: Adolescent; Adult; Chromatography, High Pressure Liquid; Female; Histamine; Histamine H1 Antagonists | 1994 |
Effect of oxatomide on experimental allergic rhinitis in guinea pigs.
Topics: Animals; Anti-Allergic Agents; Capillary Permeability; Guinea Pigs; Nasal Mucosa; Piperazines; Rhini | 1998 |
Clinical examinations with Tinset tablet in pollen rhinitis.
Topics: Adult; Female; Histamine H1 Antagonists; Humans; Male; Middle Aged; Piperazines; Rhinitis, Allergic, | 1987 |
Administration of Tinset tablet in rhinolaryngological disorders.
Topics: Adult; Child; Drug Evaluation; Humans; Nasal Mucosa; Piperazines; Rhinitis; Rhinitis, Allergic, Pere | 1986 |