oxatomide has been researched along with Rhinitis, Allergic, Nonseasonal in 7 studies
oxatomide: structure; an anti-allergic & an anti-asthmatic
oxatomide : A member of the class of benzimidazoles that is 1,3-dihydro-2H-benzimidazol-2-one substituted by a 3-[4-(diphenylmethyl)piperazin-1-yl]propyl group at position 1. It is an anti-allergic drug.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A double-blind study comparing oxatomide, a new oral drug with anti-allergic properties, with placebo in the treatment of patients with asthma with or without perennial rhinitis has been undertaken." | 9.05 | A controlled trial of oxatomide in the treatment of asthma with or without perennial rhinitis. Brompton Hospital/Medical Research Council Collaborative Trial. ( , 1981) |
| "A double-blind study comparing oxatomide, a new oral drug with anti-allergic properties, with placebo in the treatment of patients with asthma with or without perennial rhinitis has been undertaken." | 5.05 | A controlled trial of oxatomide in the treatment of asthma with or without perennial rhinitis. Brompton Hospital/Medical Research Council Collaborative Trial. ( , 1981) |
| "Cetirizine was significantly more effective at reducing the mean rhinorrhea score compared with oxatomide for both weeks 8 and 12 (P < 0." | 2.70 | The comparison of the efficacy and safety of cetirizine, oxatomide, ketotifen, and a placebo for the treatment of childhood perennial allergic rhinitis. ( Hsieh, JC; Lai, DS; Lee, HS; Lin, KL; Lue, KH, 2002) |
| "Oxatomide is an orally active H1-histamine receptor antagonist which, as appears to occur with some other antihistamines, also inhibits mast cell degranulation." | 2.37 | Oxatomide. A review of its pharmacodynamic properties and therapeutic efficacy. ( Avery, GS; Brogden, RN; Heel, RC; Richards, DM; Speight, TM, 1984) |
| " Second-generation antihistamines have become increasingly popular because of their comparable efficacy and lower incidence of adverse effects relative to their first-generation counterparts, and the safety and efficacy of this drug class are established in the adult population." | 1.35 | Treatment of allergic rhinitis in infants and children: efficacy and safety of second-generation antihistamines and the leukotriene receptor antagonist montelukast. ( Moeller, ML; Nahata, MC; Phan, H, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (42.86) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 3 (42.86) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Phan, H | 1 |
| Moeller, ML | 1 |
| Nahata, MC | 1 |
| Lai, DS | 1 |
| Lue, KH | 1 |
| Hsieh, JC | 1 |
| Lin, KL | 1 |
| Lee, HS | 1 |
| Richards, DM | 1 |
| Brogden, RN | 1 |
| Heel, RC | 1 |
| Speight, TM | 1 |
| Avery, GS | 1 |
| Kaise, T | 1 |
| Ohmori, K | 1 |
| Ukai, K | 1 |
| Sakakura, Y | 1 |
| Kakimoto, M | 1 |
| Sugimoto, Y | 1 |
| Harada, M | 1 |
| Kobayashi, Y | 1 |
| Okuma, C | 1 |
| Taga, C | 1 |
| Kamei, C | 1 |
| Zelen, B | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effectiveness of Montelukast Versus Intranasal Fluticasone Propionate in the Management of Allergic Rhinitis Among Children 02 to 05 Years of Age[NCT04957927] | Phase 4 | 60 participants (Anticipated) | Interventional | 2020-12-12 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for oxatomide and Rhinitis, Allergic, Nonseasonal
| Article | Year |
|---|---|
Oxatomide. A review of its pharmacodynamic properties and therapeutic efficacy.
Topics: Animals; Asthma; Basophils; Histamine H1 Antagonists; Histamine Release; Humans; Hypersensitivity; I | 1984 |
2 trials available for oxatomide and Rhinitis, Allergic, Nonseasonal
| Article | Year |
|---|---|
The comparison of the efficacy and safety of cetirizine, oxatomide, ketotifen, and a placebo for the treatment of childhood perennial allergic rhinitis.
Topics: Allergens; Animals; Anti-Allergic Agents; Blood Proteins; Cetirizine; Child; Conjunctivitis, Allergi | 2002 |
A controlled trial of oxatomide in the treatment of asthma with or without perennial rhinitis. Brompton Hospital/Medical Research Council Collaborative Trial.
Topics: Adolescent; Adult; Asthma; Clinical Trials as Topic; Double-Blind Method; Female; Histamine H1 Antag | 1981 |
4 other studies available for oxatomide and Rhinitis, Allergic, Nonseasonal
| Article | Year |
|---|---|
Treatment of allergic rhinitis in infants and children: efficacy and safety of second-generation antihistamines and the leukotriene receptor antagonist montelukast.
Topics: Acetates; Administration, Oral; Adult; Anti-Allergic Agents; Anti-Asthmatic Agents; Astemizole; Ceti | 2009 |
Effect of oxatomide nasal spray on experimental allergic rhinitis in guinea pigs and rats.
Topics: Administration, Intranasal; Animals; Guinea Pigs; Histamine H1 Antagonists; Histamine Release; Male; | 1995 |
Effects of fujibitol, a remedy for nasal symptoms, on experimental allergic rhinitis in rats.
Topics: Animals; Anti-Allergic Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Histamine R | 2000 |
Administration of Tinset tablet in rhinolaryngological disorders.
Topics: Adult; Child; Drug Evaluation; Humans; Nasal Mucosa; Piperazines; Rhinitis; Rhinitis, Allergic, Pere | 1986 |