oxatomide has been researched along with Muscle Contraction in 8 studies
oxatomide: structure; an anti-allergic & an anti-asthmatic
oxatomide : A member of the class of benzimidazoles that is 1,3-dihydro-2H-benzimidazol-2-one substituted by a 3-[4-(diphenylmethyl)piperazin-1-yl]propyl group at position 1. It is an anti-allergic drug.
Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Oxatomide did not cause detectable inhibition of antigen-stimulated histamine release from skin slices of sensitized guinea-pigs although the possibility that oxatomide may cause weak inhibition could not be excluded." | 1.26 | Oxatomide: in vivo assessment of antagonistic activity, and effects on histamine release and enzymatic histamine degradation in skin. ( Coutts, A; Francis, D; Gatti, S; Greaves, MW, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (87.50) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Janssens, F | 1 |
| Torremans, J | 1 |
| Janssen, M | 1 |
| Stokbroekx, RA | 1 |
| Luyckx, M | 1 |
| Janssen, PA | 1 |
| Ohmori, K | 1 |
| Ishii, H | 1 |
| Nito, M | 1 |
| Shuto, K | 1 |
| Nakamizo, N | 1 |
| Fujii, K | 1 |
| Yonehara, S | 1 |
| Takasugi, S | 1 |
| Ueda, T | 1 |
| Mukai, M | 1 |
| Gatti, S | 1 |
| Coutts, A | 1 |
| Francis, D | 1 |
| Greaves, MW | 1 |
| Tanaka, Y | 1 |
| Masai, E | 1 |
| Yashima, T | 1 |
| Furukawa, M | 1 |
| Nolan, JC | 1 |
| Stephens, DJ | 1 |
| Proakis, AG | 1 |
| Leonard, CA | 1 |
| Johnson, DN | 1 |
| Kilpatrick, BF | 1 |
| Foxwell, MH | 1 |
| Yanni, JM | 1 |
| Nijkamp, FP | 1 |
| Folkerts, G | 1 |
| Beetens, JR | 1 |
| De Clerck, F | 1 |
| Grupe, R | 1 |
| Pietzsch, W | 1 |
8 other studies available for oxatomide and Muscle Contraction
| Article | Year |
|---|---|
New antihistaminic N-heterocyclic 4-piperidinamines. 1. Synthesis and antihistaminic activity of N-(4-piperidinyl)-1H-benzimidazol-2-amines.
Topics: Administration, Oral; Animals; Benzimidazoles; Biological Assay; Chemical Phenomena; Chemistry; Guin | 1985 |
[Pharmacological studies on oxatomide (KW-4354). (7) Antagonistic effects on chemical mediators].
Topics: Acetylcholine; Animals; Bradykinin; Bronchi; Calcium Channel Blockers; Capillary Permeability; Cats; | 1983 |
[Effect of 1-[3-[4-(diphenylmethyl)-1-priperazinyl]-propyl]-1,3-dihydro-2H-benzimidazol-2- one (oxatomide) on contraction of canine bronchial muscle].
Topics: Animals; Antigens; Ascaris; Bronchi; Chlorpheniramine; Cromolyn Sodium; Dogs; Histamine H1 Antagonis | 1983 |
Oxatomide: in vivo assessment of antagonistic activity, and effects on histamine release and enzymatic histamine degradation in skin.
Topics: Acetylcholine; Animals; Dose-Response Relationship, Drug; Guinea Pigs; Histamine H1 Antagonists; His | 1980 |
[Antiallergic effects of a novel compound, SWR-00151].
Topics: Animals; Anti-Allergic Agents; Asthma; Bronchoconstriction; Cells, Cultured; Depression, Chemical; D | 1997 |
Rocastine (AHR-11325), a rapid acting, nonsedating antihistamine.
Topics: Anaphylaxis; Animals; Astemizole; Azepines; Benzhydryl Compounds; Benzimidazoles; Brompheniramine; C | 1989 |
Suppression of PAF-induced bronchoconstriction in the guinea-pig by oxatomide: mechanism of action.
Topics: Adenosine Triphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Blood Cell Count; Blood Platel | 1989 |
Inhibition of antigen-induced contractions of ileum segments and lung parenchymal strips of actively sensitized guinea pigs by different anti-allergic agents in vitro.
Topics: Animals; Antigens; Clemastine; Cromolyn Sodium; Diterpenes; Ginkgolides; Guinea Pigs; Ileum; In Vitr | 1988 |