oxatomide has been researched along with Leukemia in 1 studies
oxatomide: structure; an anti-allergic & an anti-asthmatic
oxatomide : A member of the class of benzimidazoles that is 1,3-dihydro-2H-benzimidazol-2-one substituted by a 3-[4-(diphenylmethyl)piperazin-1-yl]propyl group at position 1. It is an anti-allergic drug.
Leukemia: A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Oxatomide inhibit P-glycoprotein pump-efflux activity and the binding of [3H]-azidopine to the cell-surface protein P-glycoprotein, in a dose-related manner." | 5.31 | Circumvention of acquired resistance to doxorubicin in K562 human leukemia cells by oxatomide. ( Fujita, R; Furusawa, S; Ishikawa, M; Sasaki, K; Satoh, S; Takayanagi, M, 2001) |
| "Oxatomide inhibit P-glycoprotein pump-efflux activity and the binding of [3H]-azidopine to the cell-surface protein P-glycoprotein, in a dose-related manner." | 1.31 | Circumvention of acquired resistance to doxorubicin in K562 human leukemia cells by oxatomide. ( Fujita, R; Furusawa, S; Ishikawa, M; Sasaki, K; Satoh, S; Takayanagi, M, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ishikawa, M | 1 |
| Fujita, R | 1 |
| Furusawa, S | 1 |
| Takayanagi, M | 1 |
| Sasaki, K | 1 |
| Satoh, S | 1 |
1 other study available for oxatomide and Leukemia
| Article | Year |
|---|---|
Circumvention of acquired resistance to doxorubicin in K562 human leukemia cells by oxatomide.
Topics: Anti-Bacterial Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Membrane; Cell | 2001 |