oxatomide has been researched along with Leukemia, Basophilic, Acute in 3 studies
oxatomide: structure; an anti-allergic & an anti-asthmatic
oxatomide : A member of the class of benzimidazoles that is 1,3-dihydro-2H-benzimidazol-2-one substituted by a 3-[4-(diphenylmethyl)piperazin-1-yl]propyl group at position 1. It is an anti-allergic drug.
Leukemia, Basophilic, Acute: A rare acute myeloid leukemia in which the primary differentiation is to BASOPHILS. It is characterized by an extreme increase of immature basophilic granulated cells in the bone marrow and blood. Mature basophils are usually sparse.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Oxatomide is an H1 antihistaminic drug that also inhibits mediator release from mast cells." | 1.30 | Influence of the antiallergic drug oxatomide and derivatives on membrane structures: relation with inhibition of calcium influx in rat basophilic leukemia cells. ( de Mol, NJ; Fischer, MJ; Janssen, LH; Paulussen, JJ; v Miltenburg, JC; Zuidam, NJ, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fischer, MJ | 3 |
| Paulussen, JJ | 3 |
| Horbach, DA | 1 |
| Roelofsen, EP | 1 |
| van Miltenburg, JC | 1 |
| de Mol, NJ | 3 |
| Janssen, LH | 3 |
| Roozendaal, RL | 1 |
| van der Heijden, VC | 1 |
| van Dijken, P | 1 |
| Zuidam, NJ | 1 |
| v Miltenburg, JC | 1 |
3 other studies available for oxatomide and Leukemia, Basophilic, Acute
| Article | Year |
|---|---|
Inhibition of mediator release in RBL-2H3 cells by some H1-antagonist derived anti-allergic drugs: relation to lipophilicity and membrane effects.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Animals; Antigens; Astemizole; beta-N-Acetylhexosaminidases; Cal | 1995 |
Effects of oxatomide and derivatives on high affinity IgE receptor-activated signal transduction pathways in rat basophilic leukemia cells: role of protein tyrosine hyperphosphorylation and inhibition of extracellular calcium influx.
Topics: Animals; Anti-Allergic Agents; Calcium; Calcium Radioisotopes; Cell Adhesion; Enzyme Inhibitors; Exo | 1998 |
Influence of the antiallergic drug oxatomide and derivatives on membrane structures: relation with inhibition of calcium influx in rat basophilic leukemia cells.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Animals; Calcium; Calorimetry, Differential Scanning; Cattle; Ce | 1999 |