oxatomide and Basophilic Leukemia, Acute studies

oxatomide and Basophilic Leukemia, Acute

oxatomide: structure; an anti-allergic & an anti-asthmatic
oxatomide : A member of the class of benzimidazoles that is 1,3-dihydro-2H-benzimidazol-2-one substituted by a 3-[4-(diphenylmethyl)piperazin-1-yl]propyl group at position 1. It is an anti-allergic drug.

Research Excerpts

Excerpt	Relevance	Reference
"Oxatomide is an H1 antihistaminic drug that also inhibits mediator release from mast cells."	1.30	Influence of the antiallergic drug oxatomide and derivatives on membrane structures: relation with inhibition of calcium influx in rat basophilic leukemia cells. ( de Mol, NJ; Fischer, MJ; Janssen, LH; Paulussen, JJ; v Miltenburg, JC; Zuidam, NJ, 1999)

Research

Studies (3)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	3 (100.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Timeframe

Studies, this research(%)

All Research%

pre-1990

0 (0.00)

18.7374

1990's

3 (100.00)

18.2507

2000's

0 (0.00)

29.6817

2010's

0 (0.00)

24.3611

2020's

0 (0.00)

2.80

Authors

Authors	Studies
Fischer, MJ	3
Paulussen, JJ	3
Horbach, DA	1
Roelofsen, EP	1
van Miltenburg, JC	1
de Mol, NJ	3
Janssen, LH	3
Roozendaal, RL	1
van der Heijden, VC	1
van Dijken, P	1
Zuidam, NJ	1
v Miltenburg, JC	1

Studies

Fischer, MJ

Paulussen, JJ

Horbach, DA

Roelofsen, EP

van Miltenburg, JC

de Mol, NJ

Janssen, LH

Roozendaal, RL

van der Heijden, VC

van Dijken, P

Zuidam, NJ

v Miltenburg, JC

Other Studies

3 other studies available for oxatomide and Basophilic Leukemia, Acute

Article	Year
Inhibition of mediator release in RBL-2H3 cells by some H1-antagonist derived anti-allergic drugs: relation to lipophilicity and membrane effects. Inflammation research : official journal of the European Histamine Research Society ... [et al.], 1995, Volume: 44, Issue:2 Topics: 1,2-Dipalmitoylphosphatidylcholine; Animals; Antigens; Astemizole; beta-N-Acetylhexosaminidases; Cal	1995
Effects of oxatomide and derivatives on high affinity IgE receptor-activated signal transduction pathways in rat basophilic leukemia cells: role of protein tyrosine hyperphosphorylation and inhibition of extracellular calcium influx. Biochemical pharmacology, 1998, Sep-15, Volume: 56, Issue:6 Topics: Animals; Anti-Allergic Agents; Calcium; Calcium Radioisotopes; Cell Adhesion; Enzyme Inhibitors; Exo	1998
Influence of the antiallergic drug oxatomide and derivatives on membrane structures: relation with inhibition of calcium influx in rat basophilic leukemia cells. Biochemical pharmacology, 1999, Mar-01, Volume: 57, Issue:5 Topics: 1,2-Dipalmitoylphosphatidylcholine; Animals; Calcium; Calorimetry, Differential Scanning; Cattle; Ce	1999

Article

Year

Inhibition of mediator release in RBL-2H3 cells by some H1-antagonist derived anti-allergic drugs: relation to lipophilicity and membrane effects.

Inflammation research : official journal of the European Histamine Research Society ... [et al.], 1995, Volume: 44, Issue:2

Topics: 1,2-Dipalmitoylphosphatidylcholine; Animals; Antigens; Astemizole; beta-N-Acetylhexosaminidases; Cal

1995

Effects of oxatomide and derivatives on high affinity IgE receptor-activated signal transduction pathways in rat basophilic leukemia cells: role of protein tyrosine hyperphosphorylation and inhibition of extracellular calcium influx.

Biochemical pharmacology, 1998, Sep-15, Volume: 56, Issue:6

Topics: Animals; Anti-Allergic Agents; Calcium; Calcium Radioisotopes; Cell Adhesion; Enzyme Inhibitors; Exo

1998

Influence of the antiallergic drug oxatomide and derivatives on membrane structures: relation with inhibition of calcium influx in rat basophilic leukemia cells.

Biochemical pharmacology, 1999, Mar-01, Volume: 57, Issue:5

Topics: 1,2-Dipalmitoylphosphatidylcholine; Animals; Calcium; Calorimetry, Differential Scanning; Cattle; Ce

1999