Page last updated: 2024-11-02

oxatomide and Anaphylaxis

oxatomide has been researched along with Anaphylaxis in 8 studies

oxatomide: structure; an anti-allergic & an anti-asthmatic
oxatomide : A member of the class of benzimidazoles that is 1,3-dihydro-2H-benzimidazol-2-one substituted by a 3-[4-(diphenylmethyl)piperazin-1-yl]propyl group at position 1. It is an anti-allergic drug.

Anaphylaxis: An acute hypersensitivity reaction due to exposure to a previously encountered ANTIGEN. The reaction may include rapidly progressing URTICARIA, respiratory distress, vascular collapse, systemic SHOCK, and death.

Research Excerpts

ExcerptRelevanceReference
"Oxatomide is a new potent inhibitor of anaphylactic and allergic reactions."1.26Oxatomide, a new orally active drug which inhibits both the release and the effects of allergic mediators. ( Awouters, F; Borgers, M; Broeckaert, A; De Cree, J; Janssen, PA; Lenaerts, FM; Niemegeers, CJ; Schellekens, KH; Van den Berk, J; Van Neuten, JM, 1977)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19907 (87.50)18.7374
1990's1 (12.50)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Walsh, DA1
Franzyshen, SK1
Yanni, JM2
Ho, CY1
Hageman, WE1
Persico, FJ1
Khandwala, A1
Carlson, R1
Dally-Meade, V1
Donigi-Ruzza, D1
Kimura, S1
Watanabe, A1
Takeuchi, M1
Nagata, M1
Harada, M1
Awouters, F3
Niemegeers, CJ1
Van den Berk, J1
Van Neuten, JM1
Lenaerts, FM1
Borgers, M3
Schellekens, KH1
Broeckaert, A1
De Cree, J1
Janssen, PA2
De Brabander, M1
Van Reempts, J1
De Clerck, F1
Van Gorp, L1
Vanparijs, O1
Nolan, JC1
Stephens, DJ1
Proakis, AG1
Leonard, CA1
Johnson, DN1
Kilpatrick, BF1
Foxwell, MH1

Other Studies

8 other studies available for oxatomide and Anaphylaxis

ArticleYear
Synthesis and antiallergy activity of 4-(diarylhydroxymethyl)-1-[3-(aryloxy)propyl]piperidines and structurally related compounds.
    Journal of medicinal chemistry, 1989, Volume: 32, Issue:1

    Topics: Anaphylaxis; Animals; Benzhydryl Compounds; Chemical Phenomena; Chemistry; Drug Evaluation, Preclini

1989
Indolo[2,1-c][1,4]benzodiazepines: a new class of antiallergic agents.
    Journal of medicinal chemistry, 1986, Volume: 29, Issue:6

    Topics: Anaphylaxis; Animals; Benzodiazepines; Cromolyn Sodium; Guinea Pigs; Histamine H1 Antagonists; Hyper

1986
In vitro and in vivo activity profile of RHC 2851: a new orally effective antiallergic agent.
    Journal of immunopharmacology, 1983, Volume: 5, Issue:4

    Topics: Anaphylaxis; Animals; Basophils; Carrageenan; Cromolyn Sodium; Edema; Guinea Pigs; Histamine Release

1983
Suppressive effects of antihistaminic and/or anti-PAF agents on passive anaphylactic shock in mice sensitized with allogeneic monoclonal IgE and IgG1 antibodies and hyperimmune serum.
    Immunological investigations, 1998, Volume: 27, Issue:6

    Topics: Anaphylaxis; Animals; Antibodies, Monoclonal; Cattle; Cyproheptadine; Female; Histamine H1 Antagonis

1998
Oxatomide, a new orally active drug which inhibits both the release and the effects of allergic mediators.
    Experientia, 1977, Dec-15, Volume: 33, Issue:12

    Topics: Administration, Oral; Anaphylaxis; Animals; Dogs; Guinea Pigs; Histamine H1 Antagonists; Humans; Hyp

1977
Morphological evaluation of oxatomide--a new anti-allergic drug in guinea pig anaphylaxis.
    International archives of allergy and applied immunology, 1978, Volume: 56, Issue:6

    Topics: Anaphylaxis; Animals; Drug Evaluation; Guinea Pigs; Histamine H1 Antagonists; Hypersensitivity; Male

1978
Oxatomide protects Trichinella spiralis infected mice from lethal anaphylaxis.
    Agents and actions, 1978, Volume: 8, Issue:6

    Topics: Anaphylaxis; Animals; Male; Mice; Piperazines; Serotonin; Serotonin Antagonists; Trichinellosis

1978
Rocastine (AHR-11325), a rapid acting, nonsedating antihistamine.
    Agents and actions, 1989, Volume: 28, Issue:1-2

    Topics: Anaphylaxis; Animals; Astemizole; Azepines; Benzhydryl Compounds; Benzimidazoles; Brompheniramine; C

1989