Page last updated: 2024-11-07

oxandrolone and Turner Syndrome

oxandrolone has been researched along with Turner Syndrome in 101 studies

Oxandrolone: A synthetic hormone with anabolic and androgenic properties.

Turner Syndrome: A syndrome of defective gonadal development in phenotypic females associated with the karyotype 45,X (or 45,XO). Patients generally are of short stature with undifferentiated GONADS (streak gonads), SEXUAL INFANTILISM, HYPOGONADISM, webbing of the neck, cubitus valgus, elevated GONADOTROPINS, decreased ESTRADIOL level in blood, and CONGENITAL HEART DEFECTS. NOONAN SYNDROME (also called Pseudo-Turner Syndrome and Male Turner Syndrome) resembles this disorder; however, it occurs in males and females with a normal karyotype and is inherited as an autosomal dominant.

Research Excerpts

ExcerptRelevanceReference
"The UK Turner syndrome (TS) study examined the effect on final height of oxandrolone 0."9.41Effect of oxandrolone and timing of pubertal induction on final height in Turner syndrome: final analysis of the UK randomised placebo-controlled trial. ( Betts, P; Casey, S; Cole, TJ; Donaldson, MDC; Dunger, DB; Gault, EJ; Hindmarsh, PC, 2021)
"To evaluate karyotype-specific ear and hearing problems in young-adult patients with Turner syndrome (TS) and assess the effects of previous treatment with oxandrolone (Ox)."9.19Karyotype-specific ear and hearing problems in young adults with Turner syndrome and the effect of oxandrolone treatment. ( Admiraal, RJ; de Muinck Keizer-Schrama, SM; Freriks, K; Hermus, AR; Huygen, PL; Kunst, HP; Menke, LA; Otten, BJ; Pennings, RJ; Sas, TC; Smeets, DF; Timmers, HJ; Topsakal, V; van Alfen-van der Velden, JA; Verver, EJ; Wit, JM, 2014)
"The weak androgen oxandrolone (Ox) may increase height but may also affect glucose metabolism in girls with Turner syndrome (TS)."9.15Effect of oxandrolone on glucose metabolism in growth hormone-treated girls with Turner syndrome. ( de Muinck Keizer-Schrama, SM; Menke, LA; Otten, BJ; Sas, TC; Stijnen, T; Wit, JM; Zandwijken, GR, 2011)
"Oxandrolone (Ox) increases height gain but may also cause voice deepening in growth hormone (GH)-treated girls with Turner syndrome (TS)."9.15The effect of oxandrolone on voice frequency in growth hormone-treated girls with Turner syndrome. ( Boersma, B; de Muinck Keizer-Schrama, SM; de Ridder, MA; Dejonckere, PH; Menke, LA; Otten, BJ; Sas, TC; van Koningsbrugge, SH; Wit, JM; Zandwijken, GR, 2011)
"The weak androgen oxandrolone (Ox) increases height gain in growth-hormone (GH) treated girls with Turner syndrome (TS), but may also give rise to virilizing side effects."9.14The effect of the weak androgen oxandrolone on psychological and behavioral characteristics in growth hormone-treated girls with Turner syndrome. ( Cohen-Kettenis, PT; de Muinck Keizer-Schrama, SM; Kreukels, BP; Menke, LA; Otten, BJ; Sas, TC; Stijnen, T; Visser, M; Wit, JM; Zandwijken, GR, 2010)
"The objective of this study was to find out whether moderate doses of growth hormone (GH) in combination with oxandrolone (Ox) and late initiation of puberty could improve adult height even in relatively old patients with Ullrich-Turner syndrome (UTS)."9.10Favorable final height outcome in girls with Ullrich-Turner syndrome treated with low-dose growth hormone together with oxandrolone despite starting treatment after 10 years of age. ( Keller, E; Landy, H; Stahnke, N, 2002)
"The aims of this comparative multicenter study of 67 girls with Turner syndrome (TS) on three different therapeutical regimens were, first, to evaluate the effect of either recombinant human growth hormone (GH) alone or in combination with the anabolic steroid oxandrolone (Oxa) on height velocity and on Turner-specific bone age (BA'TS) and, second, to estimate the gain in final height taking the age at the onset of treatment into account."9.08Growth promotion and Turner-specific bone age after therapy with growth hormone and in combination with oxandrolone: when should therapy be started in Turner syndrome? ( Joss, EE; Mullis, PE; Partsch, CJ; Sippell, WG; Werder, EA, 1997)
"Final stature in girls with Turner syndrome treated with combination of low dose oestrogen and oxandrolone."9.08Final height outcome in girls with Turner syndrome treated with a combination of low dose oestrogen and oxandrolone. ( Bareille, P; Massarano, AA; Stanhope, R, 1997)
"Seventy girls with Turner syndrome, verified by karyotype, were randomly assigned to observation or treatment with human growth hormone (hGH), oxandrolone, or a combination of hGH plus oxandrolone for a period of 12 to 24 months, to assess the effect of treatment on growth velocity and adult height."9.07Six-year results of a randomized, prospective trial of human growth hormone and oxandrolone in Turner syndrome. ( Attie, KM; Brasel, JA; Burstein, S; Cara, JF; Chernausek, S; Frane, J; Gotlin, RW; Kuntze, J; Lippe, BM; Rosenfeld, RG, 1992)
"In order to examine whether the anabolic steroid oxandrolone has any long-term effect on height in Turner syndrome, the short- and long-term effects were studied in a group of 35 individuals with the syndrome."9.06Oxandrolone increases final height in Turner syndrome. ( Crock, P; Werther, GA; Wettenhall, HN, 1990)
"Seventy girls with Turner syndrome, 4 to 12 years of age, participated in a prospective, randomized study to determine the effects on growth of methionyl human growth hormone (met-hGH) or oxandrolone."9.06Three-year results of a randomized prospective trial of methionyl human growth hormone and oxandrolone in Turner syndrome. ( Brasel, JA; Burstein, S; Chernausek, S; Compton, P; Frane, J; Gotlin, RW; Hintz, RL; Johanson, AJ; Rosenfeld, RG; Sherman, B, 1988)
"To assess the effects of oxandrolone on growth hormone-treated girls aged up to 18 years with Turner syndrome."9.01Oxandrolone for growth hormone-treated girls aged up to 18 years with Turner syndrome. ( Adi, YA; AlFaleh, K; Alkofide, H; Amer, YS; Mohamed, S, 2019)
"There has been no consensus regarding the efficacy and safety of oxandrolone (Ox) in addition to growth hormone (GH) in girls with Turner syndrome (TS), the optimal age of starting this treatment, or the optimal dose."8.90Safety and efficacy of oxandrolone in growth hormone-treated girls with Turner syndrome: evidence from recent studies and recommendations for use. ( Bardsley, MZ; de Muinck Keizer-Schrama, SM; Donaldson, MD; Freriks, K; Gault, EJ; Menke, LA; Otten, BJ; Perry, RJ; Ross, JL; Sas, TC; Timmers, H; Wit, JM, 2014)
"Combined treatment with growth hormone and oxandrolone results in a significant increase of insulin secretion and increased insulin resistance."7.73[Carbohydrate metabolism in patients with Turner syndrome. The effect of therapy with growth hormone, oxandrolone and a combination of both]. ( Starzyk, J, 2005)
"In 18 girls with Turner syndrome, glucose tolerance was studied before treatment and after 6 and 24 months of growth-promoting treatment with recombinant human growth hormone (24 IU/m(2)/week; 8 mg/m(2)/week) and oxandrolone (0."7.70Effect of growth hormone and oxandrolone treatment on glucose metabolism in Turner syndrome. A longitudinal study. ( Joss, EE; Mullis, PE; Tönz, O; Zurbrügg, RP, 2000)
"To evaluate the effects of growth-promoting therapy on carbohydrate metabolism in girls with Turner syndrome, we determined glucose and insulin concentrations during oral glucose tolerance tests (OGTTs) at baseline and after 5 days, 2 months, and 12 months of treatment with growth hormone (GH), oxandrolone, or a combination of GH and oxandrolone, or after the same intervals with no therapy."7.67Carbohydrate and lipid metabolism in Turner syndrome: effect of therapy with growth hormone, oxandrolone, and a combination of both. ( Frane, JW; Hintz, RL; Johanson, AJ; Rosenfeld, RG; Sherman, B; Wilson, DM, 1988)
" The increase in BMI and waist circumference SDS was comparable between the dosage groups."6.75The effect of oxandrolone on body proportions and body composition in growth hormone-treated girls with Turner syndrome. ( de Muinck Keizer-Schrama, SM; de Ridder, MA; Menke, LA; Otten, BJ; Sas, TC; Stijnen, T; Wit, JM; Zandwijken, GR, 2010)
"In GH-treated girls with TS, we discourage the use of the conventional Ox dosage (0."6.75Efficacy and safety of oxandrolone in growth hormone-treated girls with turner syndrome. ( de Muinck Keizer-Schrama, SM; de Ridder, MA; Dejonckere, PH; Delemarre-van de Waal, HA; Gevers, EF; Hokken-Koelega, AC; Jansen, M; Menke, LA; Odink, RJ; Otten, BJ; Reeser, HM; Sas, TC; Stokvis-Brantsma, WH; van Buuren, S; van Trotsenburg, AS; Waelkens, JJ; Westerlaken, C; Wit, JM; Zandwijken, GR, 2010)
" Conventional GH doses are effective in increasing growth velocity in UTS, especially, when combined with Ox."6.68Treatment of patients with Ullrich-Turner syndrome with conventional doses of growth hormone and the combination with testosterone or oxandrolone: effect on growth, IGF-I and IGFBP-3 concentrations. ( Blümel, P; Frisch, H; Haeusler, G; Plöchl, E; Schmitt, K; Waldhör, T; Zachmann, M, 1995)
"The UK Turner syndrome (TS) study examined the effect on final height of oxandrolone 0."5.41Effect of oxandrolone and timing of pubertal induction on final height in Turner syndrome: final analysis of the UK randomised placebo-controlled trial. ( Betts, P; Casey, S; Cole, TJ; Donaldson, MDC; Dunger, DB; Gault, EJ; Hindmarsh, PC, 2021)
"Mild virilization persists in only a small minority of patients."5.39Long-term effects of previous oxandrolone treatment in adult women with Turner syndrome. ( de Muinck Keizer-Schrama, SM; Dejonckere, PH; den Heijer, M; Freriks, K; Gotthardt, M; Hermus, AR; Menke, LA; Netea-Maier, RT; Otten, BJ; Sas, TC; Timmers, HJ; Traas, MA; van Alfen-van der Velden, JA; Wit, JM; Zandwijken, GR, 2013)
"A UK study showed final height in Turner syndrome (TS) girls receiving growth hormone is affected by age at pubertal induction and oxandrolone (Ox)."5.19Effect of oxandrolone and timing of oral ethinylestradiol initiation on pubertal progression, height velocity and bone maturation in the UK Turner study. ( Donaldson, MD; Dunger, DB; Gault, EJ; Paterson, WF; Perry, RJ, 2014)
"To evaluate karyotype-specific ear and hearing problems in young-adult patients with Turner syndrome (TS) and assess the effects of previous treatment with oxandrolone (Ox)."5.19Karyotype-specific ear and hearing problems in young adults with Turner syndrome and the effect of oxandrolone treatment. ( Admiraal, RJ; de Muinck Keizer-Schrama, SM; Freriks, K; Hermus, AR; Huygen, PL; Kunst, HP; Menke, LA; Otten, BJ; Pennings, RJ; Sas, TC; Smeets, DF; Timmers, HJ; Topsakal, V; van Alfen-van der Velden, JA; Verver, EJ; Wit, JM, 2014)
"The weak androgen oxandrolone (Ox) may increase height but may also affect glucose metabolism in girls with Turner syndrome (TS)."5.15Effect of oxandrolone on glucose metabolism in growth hormone-treated girls with Turner syndrome. ( de Muinck Keizer-Schrama, SM; Menke, LA; Otten, BJ; Sas, TC; Stijnen, T; Wit, JM; Zandwijken, GR, 2011)
"Oxandrolone (Ox) increases height gain but may also cause voice deepening in growth hormone (GH)-treated girls with Turner syndrome (TS)."5.15The effect of oxandrolone on voice frequency in growth hormone-treated girls with Turner syndrome. ( Boersma, B; de Muinck Keizer-Schrama, SM; de Ridder, MA; Dejonckere, PH; Menke, LA; Otten, BJ; Sas, TC; van Koningsbrugge, SH; Wit, JM; Zandwijken, GR, 2011)
"The weak androgen oxandrolone (Ox) increases height gain in growth-hormone (GH) treated girls with Turner syndrome (TS), but may also give rise to virilizing side effects."5.14The effect of the weak androgen oxandrolone on psychological and behavioral characteristics in growth hormone-treated girls with Turner syndrome. ( Cohen-Kettenis, PT; de Muinck Keizer-Schrama, SM; Kreukels, BP; Menke, LA; Otten, BJ; Sas, TC; Stijnen, T; Visser, M; Wit, JM; Zandwijken, GR, 2010)
"The objective of this study was to find out whether moderate doses of growth hormone (GH) in combination with oxandrolone (Ox) and late initiation of puberty could improve adult height even in relatively old patients with Ullrich-Turner syndrome (UTS)."5.10Favorable final height outcome in girls with Ullrich-Turner syndrome treated with low-dose growth hormone together with oxandrolone despite starting treatment after 10 years of age. ( Keller, E; Landy, H; Stahnke, N, 2002)
"Final stature in girls with Turner syndrome treated with combination of low dose oestrogen and oxandrolone."5.08Final height outcome in girls with Turner syndrome treated with a combination of low dose oestrogen and oxandrolone. ( Bareille, P; Massarano, AA; Stanhope, R, 1997)
"The aims of this comparative multicenter study of 67 girls with Turner syndrome (TS) on three different therapeutical regimens were, first, to evaluate the effect of either recombinant human growth hormone (GH) alone or in combination with the anabolic steroid oxandrolone (Oxa) on height velocity and on Turner-specific bone age (BA'TS) and, second, to estimate the gain in final height taking the age at the onset of treatment into account."5.08Growth promotion and Turner-specific bone age after therapy with growth hormone and in combination with oxandrolone: when should therapy be started in Turner syndrome? ( Joss, EE; Mullis, PE; Partsch, CJ; Sippell, WG; Werder, EA, 1997)
"Seventy girls with Turner syndrome, verified by karyotype, were randomly assigned to observation or treatment with human growth hormone (hGH), oxandrolone, or a combination of hGH plus oxandrolone for a period of 12 to 24 months, to assess the effect of treatment on growth velocity and adult height."5.07Six-year results of a randomized, prospective trial of human growth hormone and oxandrolone in Turner syndrome. ( Attie, KM; Brasel, JA; Burstein, S; Cara, JF; Chernausek, S; Frane, J; Gotlin, RW; Kuntze, J; Lippe, BM; Rosenfeld, RG, 1992)
"Beginning in 1983, 71 girls with Turner syndrome were enrolled in a prospective, randomized study of human growth hormone (hGH), alone and in combination with oxandrolone; 4-5 patient-year data are currently available on 66 subjects."5.06Non-conventional growth hormone therapy in Turner syndrome: the United States experience. ( Rosenfeld, RG, 1990)
"In 1983, a multicenter, collaborative, prospective study was begun to investigate the efficacy of human growth hormone (hGH), alone and in combination with oxandrolone, in girls with Turner syndrome."5.06Acceleration of growth in Turner syndrome patients treated with growth hormone: summary of three-year results. ( Rosenfeld, RG, 1989)
"Seventy girls with Turner syndrome, 4 to 12 years of age, participated in a prospective, randomized study to determine the effects on growth of methionyl human growth hormone (met-hGH) or oxandrolone."5.06Three-year results of a randomized prospective trial of methionyl human growth hormone and oxandrolone in Turner syndrome. ( Brasel, JA; Burstein, S; Chernausek, S; Compton, P; Frane, J; Gotlin, RW; Hintz, RL; Johanson, AJ; Rosenfeld, RG; Sherman, B, 1988)
"In order to examine whether the anabolic steroid oxandrolone has any long-term effect on height in Turner syndrome, the short- and long-term effects were studied in a group of 35 individuals with the syndrome."5.06Oxandrolone increases final height in Turner syndrome. ( Crock, P; Werther, GA; Wettenhall, HN, 1990)
"The linear growth effects of oxandrolone, human growth hormone, and Ox + hGH were compared in six girls, age 11 to 15 years, with X chromosome abnormalities (three with X,O karyotype, three with Turner syndrome variants)."5.05Effect of growth hormone and oxandrolone singly and together on growth rate in girls with X chromosome abnormalities. ( Blackston, D; Goldsmith, M; Kutner, M; Rudman, D, 1980)
"To assess the effects of oxandrolone on growth hormone-treated girls aged up to 18 years with Turner syndrome."5.01Oxandrolone for growth hormone-treated girls aged up to 18 years with Turner syndrome. ( Adi, YA; AlFaleh, K; Alkofide, H; Amer, YS; Mohamed, S, 2019)
" The addition of oxandrolone to growth hormone (GH) in Turner syndrome has an additive effect on adult height gain."4.91Novel approaches to short stature therapy. ( Oostdijk, W; Wit, JM, 2015)
"There has been no consensus regarding the efficacy and safety of oxandrolone (Ox) in addition to growth hormone (GH) in girls with Turner syndrome (TS), the optimal age of starting this treatment, or the optimal dose."4.90Safety and efficacy of oxandrolone in growth hormone-treated girls with Turner syndrome: evidence from recent studies and recommendations for use. ( Bardsley, MZ; de Muinck Keizer-Schrama, SM; Donaldson, MD; Freriks, K; Gault, EJ; Menke, LA; Otten, BJ; Perry, RJ; Ross, JL; Sas, TC; Timmers, H; Wit, JM, 2014)
"Combined treatment with growth hormone and oxandrolone results in a significant increase of insulin secretion and increased insulin resistance."3.73[Carbohydrate metabolism in patients with Turner syndrome. The effect of therapy with growth hormone, oxandrolone and a combination of both]. ( Starzyk, J, 2005)
"To evaluate bone mass in patients with Turner syndrome by measuring metacarpal cortical thickness and bone diameter before and after treatment with oxandrolone, growth hormone (GH) and estrogens."3.73[Study of bone mass in Turner syndrome]. ( Cancer Gaspar, E; Ferrández Longás, A; Labarta Aizpún, JI; Mayayo Dehesa, E; Ruiz-Echarri Zelaya, M, 2005)
"In 18 girls with Turner syndrome, glucose tolerance was studied before treatment and after 6 and 24 months of growth-promoting treatment with recombinant human growth hormone (24 IU/m(2)/week; 8 mg/m(2)/week) and oxandrolone (0."3.70Effect of growth hormone and oxandrolone treatment on glucose metabolism in Turner syndrome. A longitudinal study. ( Joss, EE; Mullis, PE; Tönz, O; Zurbrügg, RP, 2000)
"To evaluate the effects of growth-promoting therapy on carbohydrate metabolism in girls with Turner syndrome, we determined glucose and insulin concentrations during oral glucose tolerance tests (OGTTs) at baseline and after 5 days, 2 months, and 12 months of treatment with growth hormone (GH), oxandrolone, or a combination of GH and oxandrolone, or after the same intervals with no therapy."3.67Carbohydrate and lipid metabolism in Turner syndrome: effect of therapy with growth hormone, oxandrolone, and a combination of both. ( Frane, JW; Hintz, RL; Johanson, AJ; Rosenfeld, RG; Sherman, B; Wilson, DM, 1988)
"Twenty-five patients with Turner Syndrome were treated with oxandrolone for six or more months."3.65Studies of anabolic steroids. VI. Effect of prolonged administration of oxandrolone on growth in children and adolescents with gonadal dysgenesis. ( Kelley, VC; Limbeck, GA; Moore, DC; Ruvalcaba, RH; Tattoni, DS, 1977)
"Girls with Turner's syndrome aged 7-13 years at recruitment, receiving recombinant growth hormone therapy (10 mg/m(2)/week)."2.76Effect of oxandrolone and timing of pubertal induction on final height in Turner's syndrome: randomised, double blind, placebo controlled trial. ( Betts, P; Casey, S; Cole, TJ; Donaldson, MD; Dunger, DB; Gault, EJ; Hindmarsh, PC; Paterson, WF; Perry, RJ, 2011)
" The increase in BMI and waist circumference SDS was comparable between the dosage groups."2.75The effect of oxandrolone on body proportions and body composition in growth hormone-treated girls with Turner syndrome. ( de Muinck Keizer-Schrama, SM; de Ridder, MA; Menke, LA; Otten, BJ; Sas, TC; Stijnen, T; Wit, JM; Zandwijken, GR, 2010)
"In GH-treated girls with TS, we discourage the use of the conventional Ox dosage (0."2.75Efficacy and safety of oxandrolone in growth hormone-treated girls with turner syndrome. ( de Muinck Keizer-Schrama, SM; de Ridder, MA; Dejonckere, PH; Delemarre-van de Waal, HA; Gevers, EF; Hokken-Koelega, AC; Jansen, M; Menke, LA; Odink, RJ; Otten, BJ; Reeser, HM; Sas, TC; Stokvis-Brantsma, WH; van Buuren, S; van Trotsenburg, AS; Waelkens, JJ; Westerlaken, C; Wit, JM; Zandwijken, GR, 2010)
"The oxandrolone-treated group demonstrated improved performance after 2 yr, compared with the placebo group (P < 0."2.71Androgen-responsive aspects of cognition in girls with Turner syndrome. ( Bondy, C; Cutler, GB; Feuillan, P; Kushner, H; Roeltgen, D; Ross, JL; Stefanatos, GA, 2003)
" These data indicate that long term administration of rhGH has no significant impact on serum Lp(a) levels in girls with Turner's syndrome."2.69Long-term treatment with growth hormone has no persisting effect on lipoprotein(a) in patients with Turner's syndrome. ( Döpper, S; Gradehand, A; Kiencke, P; Querfeld, U; Wahn, F; Zeisel, HJ, 1999)
"The agonadal model, girls with Turner's syndrome (TS), has been used to determine the role of the hypothalamic pulse generator in the ontogeny of gonadotrophin secretion in man."2.69Gonadotrophin pulsatility in girls with the Turner syndrome: modulation by exogenous sex steroids. ( Brook, CG; Hindmarsh, PC; Massarano, AA; Nathwani, NC, 1998)
" Conventional GH doses are effective in increasing growth velocity in UTS, especially, when combined with Ox."2.68Treatment of patients with Ullrich-Turner syndrome with conventional doses of growth hormone and the combination with testosterone or oxandrolone: effect on growth, IGF-I and IGFBP-3 concentrations. ( Blümel, P; Frisch, H; Haeusler, G; Plöchl, E; Schmitt, K; Waldhör, T; Zachmann, M, 1995)
"A total of 70 subjects with Turner's syndrome from 11 centres were enrolled in a study of somatrem."2.66Results from the first 2 years of a clinical trial with recombinant DNA-derived human growth hormone (somatrem) in Turner's syndrome. ( Hintz, RL; Johanson, AJ; Rosenfeld, RG; Sherman, B, 1987)
"Control patients with Turner's syndrome were matched by using the following criteria: difference in bone age being not greater than 0."2.65Oxandrolone in girls with Turner's syndrome. A pair-matched controlled study up to final height. ( Joss, E; Zuppinger, K, 1984)
"Turner's syndrome is the commonest sex chromosome abnormality in females, resulting from the absence of an X chromosome or the presence of a structurally abnormal X chromosome."2.42Growth and puberty in Turner's syndrome. ( Baroncelli, GI; Bertelloni, S; Fruzzetti, F; Saggese, G; Simi, P; Spinelli, C, 2003)
" Oestrogens are needed for secondary sex characteristics, but should be given in a low dosage and at approximately 12-13 years of age, in order not to compromise final height."2.38[Turner syndrome: a virtually certain indication for growth hormone treatment]. ( Rongen-Westerlaken, C; Wit, JM, 1992)
"Girls with Turner's Syndrome respond to growth hormone therapy."2.38Growth hormone therapy in Turner's syndrome. ( O'Shea, D; Powell, D, 1992)
"Children with Turner's syndrome will not have the same growth response as children who have classical growth hormone insufficiency."2.38Treatment of growth hormone insufficiency. ( Hindmarsh, PC, 1990)
"Turner syndrome is characterized by a great variability of clinical manifestations caused by a total or partial loss of X-chromosome."1.42Turner syndrome: From birth to adulthood. ( Grau Bolado, G; Martinez-Indart, L; Rica Echevarria, I; Ríos Orbañanos, I; Rodriguez Estevez, A; Vela Desojo, A, 2015)
"Mild virilization persists in only a small minority of patients."1.39Long-term effects of previous oxandrolone treatment in adult women with Turner syndrome. ( de Muinck Keizer-Schrama, SM; Dejonckere, PH; den Heijer, M; Freriks, K; Gotthardt, M; Hermus, AR; Menke, LA; Netea-Maier, RT; Otten, BJ; Sas, TC; Timmers, HJ; Traas, MA; van Alfen-van der Velden, JA; Wit, JM; Zandwijken, GR, 2013)
"A number of typical features of Turner's syndrome were found, including a short webbed neck, cubitus valgus, shield chest, multiple pigmented nevi, lymphedema, epicanthus and micrognathia."1.35Hormonal therapy in a patient with a delayed diagnosis of Turner's syndrome. ( Gawlik, A; Malecka-Tendera, E, 2008)
"Patients with Turner syndrome have higher blood pressure measurements compared to published population standards, as evidenced by the shift to the right of both the systolic and diastolic BP SDS."1.31Blood pressure and Turner syndrome. ( Brook, CG; Hindmarsh, PC; Nathwani, NC; Unwin, R, 2000)
"We have studied the course over age of fasting insulin, sex hormone-binding globulin (SHBG), and insulin-like growth factor (IGF)-binding protein-1 (IGFBP-1) in untreated children with Turner's syndrome (TS) and measured the course of these parameters during therapy with GH alone and in combination with oxandrolone."1.29Insulin, insulin-like growth factor-binding protein-1, and sex hormone-binding globulin in patients with Turner's syndrome: course over age in untreated patients and effect of therapy with growth hormone alone and in combination with oxandrolone. ( Blümel, P; Frisch, H; Haeusler, G; Plöchl, E; Schmitt, K; Waldhör, T, 1996)
" The dosage were: GH, 0."1.29Improved final height in girls with Turner's syndrome treated with growth hormone and oxandrolone. ( Albertsson-Wikland, K; Alm, J; Aman, J; Aronson, S; Gustafsson, J; Hagenäs, L; Häger, A; Ivarsson, SA; Karlberg, J; Kriström, B; Marcus, C; Moell, C; Nilsson, KO; Ritzen, M; Tuvemo, T; Wattsgård, C; Westgren, U; Westphal, O, 1996)
" Subsequently, all patients received GH 18 IU/m2/week in combination with oxandrolone (Ox) (0."1.29Growth hormone in combination with anabolic steroids in patients with Turner syndrome: effect on bone maturation and final height. ( Blümel, P; Frisch, H; Haeusler, G; Plöchl, E; Schmitt, K; Waldhör, T, 1996)
"Patients with Turner's syndrome who had lower basal IGF-I levels had significantly higher responses of IGF-I, free fatty acids and hydroxyproline (P less than 0."1.28Growth hormone treatment in Turner's syndrome: short and long-term effects on metabolic parameters. ( Frisch, H; Haeusler, G, 1992)
"Forty-eight girls with Turner's syndrome were assigned to one of three treatments; recombinant human growth hormone (rhGH) alone, rhGH plus oxandrolone, and rhGH plus ethinyloestradiol."1.28Effect of recombinant human growth hormone therapy on bone and clinical parameters in girls with Turner's syndrome. The Spanish Collaborative Group. ( Anton, R; Arnal, JM; Buñuel, C; Ferrández, A; García, C; Lasarte, JJ; Mayayo, E; Puyuelo, P, 1989)
"To evaluate the relationship between the secretion of gonadotropins and adrenal androgens, patients with gonadal agenesis were evaluated by (a) administering human luteinizing hormone (hLH) for 5 days with or without estrogen pretreatment to agonadal patients who had prepubertal LH levels; (b) correlating circulating gonadotropin levels with adrenal androgens in 45 patients; and (c) comparing adrenal androgens with gonadotropins after long-term administration of estrogen or androgens."1.25Lack of correlation between gonadotropin and adrenal androgen levels in agonadal children. ( Blizzard, RM; Kowarski, A; Lee, PA; Migeon, CJ, 1975)

Research

Studies (101)

TimeframeStudies, this research(%)All Research%
pre-199026 (25.74)18.7374
1990's35 (34.65)18.2507
2000's19 (18.81)29.6817
2010's20 (19.80)24.3611
2020's1 (0.99)2.80

Authors

AuthorsStudies
Mohamed, S1
Alkofide, H1
Adi, YA1
Amer, YS1
AlFaleh, K1
Gault, EJ5
Cole, TJ3
Casey, S2
Hindmarsh, PC7
Betts, P2
Dunger, DB3
Donaldson, MDC1
Perry, RJ3
Paterson, WF2
Donaldson, MD5
Sas, TC10
Bardsley, MZ1
Menke, LA10
Freriks, K4
Otten, BJ9
de Muinck Keizer-Schrama, SM9
Timmers, H1
Wit, JM12
Ross, JL4
Verver, EJ1
Huygen, PL1
Pennings, RJ1
Smeets, DF2
Hermus, AR3
van Alfen-van der Velden, JA2
Topsakal, V1
Admiraal, RJ1
Timmers, HJ3
Kunst, HP1
Verhaak, CM1
Netea-Maier, RT2
Kessels, RP1
Oostdijk, W1
Ríos Orbañanos, I1
Vela Desojo, A1
Martinez-Indart, L1
Grau Bolado, G1
Rodriguez Estevez, A1
Rica Echevarria, I1
Mazzocco, MM1
Kushner, H3
Kowal, K2
Cutler, GB3
Roeltgen, D2
Visser, M1
Kreukels, BP1
Stijnen, T3
Zandwijken, GR6
Cohen-Kettenis, PT1
de Ridder, MA3
Odink, RJ1
Jansen, M1
Delemarre-van de Waal, HA1
Stokvis-Brantsma, WH1
Waelkens, JJ1
Westerlaken, C1
Reeser, HM1
van Trotsenburg, AS1
Gevers, EF1
van Buuren, S1
Dejonckere, PH3
Hokken-Koelega, AC1
Andrade, AC1
Baron, J1
Manolagas, SC1
Shaw, NJ1
Rappold, GA1
Sävendahl, L2
Ben-Shlomo, Y1
Zeger, MP1
Shah, K1
van Koningsbrugge, SH1
Boersma, B1
Fonteles, AV1
Dondoni, RS1
Boguszewski, MC1
Nesi-França, S1
Marques-Pereira, R1
Sandrini Neto, R1
Lacerda Filho, Ld1
Davenport, ML1
Traas, MA1
den Heijer, M1
Gotthardt, M1
Stefanatos, GA1
Feuillan, P1
Bondy, C1
Ságodi, L1
Sólyom, E1
Bertelloni, S1
Baroncelli, GI1
Fruzzetti, F1
Spinelli, C1
Simi, P1
Saggese, G1
Parvin, M1
Roche, E1
Costigan, C1
Hoey, HM1
Gracia Bouthelier, R1
Oliver Iguacel, A1
Gonzalez Casado, I1
Alcalde de Alvaré, A1
Cancer Gaspar, E1
Ruiz-Echarri Zelaya, M1
Labarta Aizpún, JI1
Mayayo Dehesa, E1
Ferrández Longás, A1
Starzyk, J1
Laurencikas, E1
Söderman, E1
Davenport, M1
Jorulf, H1
Cutter, WJ1
Daly, EM1
Robertson, DM1
Chitnis, XA1
van Amelsvoort, TA1
Simmons, A1
Ng, VW1
Williams, BS1
Shaw, P1
Conway, GS1
Skuse, DH1
Collier, DA1
Craig, M1
Murphy, DG1
Gawlik, A1
Malecka-Tendera, E1
Ramos, AV1
Silva, IN1
Goulart, EM1
Schönberger, W1
Benes, P1
Morsches, B1
Zabel, B1
Scheidt, E1
Joss, E1
Zuppinger, K1
Vuković, D1
Rudman, D1
Goldsmith, M1
Kutner, M1
Blackston, D1
Root, AW1
Stahnke, N3
Willig, RP1
Haeusler, G4
Frisch, H5
Schmitt, K4
Blümel, P5
Plöchl, E4
Zachmann, M1
Waldhör, T4
Frasier, SD1
Lippe, BM3
Ranke, MB5
Grauer, ML1
Andersson-Wallgren, G1
Albertsson-Wikland, K3
Saenger, P2
Lu, PW1
Cowell, CT1
Rochiccioli, P2
Battin, J1
Bertrand, AM1
Bost, M1
Cabrol, S1
le Bouc, Y1
Chaussain, JL1
Chatelain, P2
Colle, M1
Czernichow, P1
Nilsson, KO2
Alm, J1
Aronson, S1
Gustafsson, J1
Hagenäs, L1
Häger, A1
Ivarsson, SA1
Karlberg, J1
Kriström, B1
Marcus, C1
Moell, C1
Ritzen, M1
Tuvemo, T1
Wattsgård, C1
Westgren, U1
Westphal, O1
Aman, J1
Häusler, G1
Joss, EE3
Mullis, PE2
Werder, EA1
Partsch, CJ1
Sippell, WG1
Bareille, P1
Massarano, AA3
Stanhope, R3
Rosenfeld, RG11
Attie, KM2
Frane, J5
Brasel, JA4
Burstein, S4
Cara, JF2
Chernausek, S3
Gotlin, RW4
Kuntze, J3
Mahoney, CP1
Moore, WV1
Johanson, AJ6
Nicholls, D1
Nathwani, NC3
Brook, CG4
Querfeld, U1
Döpper, S1
Gradehand, A1
Kiencke, P1
Wahn, F1
Zeisel, HJ1
Cacciari, E1
Mazzanti, L1
Unwin, R2
Zurbrügg, RP1
Tönz, O1
Lindberg, A1
Wilton, P1
Cutfield, W1
Price, DA1
Bramswig, JH1
Keller, E2
Landy, H1
Lee, PA2
Kowarski, A1
Migeon, CJ2
Blizzard, RM1
Moore, DC1
Tattoni, DS1
Ruvalcaba, RH1
Limbeck, GA1
Kelley, VC1
Urban, MD1
Dorst, JP1
Plotnick, LP1
Crawford, JD1
Rosenfield, RL1
Lucky, AW1
Pierson, M1
Leheup, B1
Ferrández, A2
Mayayo, E2
Sanjuan, P1
Bello, E1
Labarta, JI1
Rongen-Westerlaken, C1
Stubbe, P1
Tauber, MT1
O'Shea, D1
Powell, D1
Job, JC1
Landier, F1
Cherubini, V1
Cardinale, G1
Panfoli, C1
Pecora, R1
Lorenzetti, L1
Bartolotta, E1
Crock, P1
Werther, GA1
Wettenhall, HN1
Stögmann, W1
Pringle, PJ1
Teale, JD1
Preece, MA1
Arnal, JM1
García, C1
Buñuel, C1
Lasarte, JJ1
Anton, R1
Puyuelo, P1
Lippe, B1
Hintz, RL5
Sherman, B4
Wilson, DM2
Frane, JW1
Compton, P1
Chernausek, SD1
Clabots, T1
Bryan, GT1
Rosenbloom, AL1
Frias, JL1
Rosenblum, AL1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Effects of Androgen, Estrogen, and the Combination of Androgen and Estrogen on Growth Rate and Cognitive Function of Growth Hormone-treated Girls With Turner Syndrome[NCT00029159]Phase 3200 participants (Actual)Interventional1992-11-30Completed
Comparison of Standard and Physiologic Sex Steroid Replacement Regimens in Women With Premature Ovarian Failure and the Assessment of Skeletal, Cardiovascular and Reproductive Parameters[NCT00732693]Phase 442 participants (Actual)Interventional2002-02-28Completed
A Double-Blind, Randomized, Placebo-Controlled Trial of the Effect of Biosynthetic Growth Hormone and/or Ethinyl Estradiol on Adult Height in Patients With Turner Syndrome[NCT00001221]Phase 2160 participants Interventional1987-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

20 reviews available for oxandrolone and Turner Syndrome

ArticleYear
Oxandrolone for growth hormone-treated girls aged up to 18 years with Turner syndrome.
    The Cochrane database of systematic reviews, 2019, 10-30, Volume: 2019, Issue:10

    Topics: Adolescent; Androgens; Body Height; Female; Human Growth Hormone; Humans; Oxandrolone; Randomized Co

2019
Safety and efficacy of oxandrolone in growth hormone-treated girls with Turner syndrome: evidence from recent studies and recommendations for use.
    Hormone research in paediatrics, 2014, Volume: 81, Issue:5

    Topics: Adolescent; Adult; Age Factors; Androgens; Child; Child, Preschool; Double-Blind Method; Female; Hum

2014
Novel approaches to short stature therapy.
    Best practice & research. Clinical endocrinology & metabolism, 2015, Volume: 29, Issue:3

    Topics: Achondroplasia; Androgens; Aromatase Inhibitors; Dwarfism, Pituitary; Gonadotropin-Releasing Hormone

2015
Hormones and genes of importance in bone physiology and their influence on bone mineralization and growth in Turner syndrome.
    Hormone research in paediatrics, 2010, Volume: 73, Issue:3

    Topics: Adolescent; Body Height; Bone Density; Bone Development; Bone Diseases, Metabolic; Calcification, Ph

2010
Growth and puberty in Turner's syndrome.
    Journal of pediatric endocrinology & metabolism : JPEM, 2003, Volume: 16 Suppl 2

    Topics: Anabolic Agents; Estrogen Replacement Therapy; Female; Growth; Growth Hormone; Humans; Oxandrolone;

2003
Management of Turner's syndrome.
    Journal of pediatric endocrinology & metabolism : JPEM, 2004, Volume: 17 Suppl 2

    Topics: Androgens; Body Height; Estrogens; Female; Fertility; Growth Hormone; Humans; Oxandrolone; Pregnancy

2004
Optimization of treatment in Turner's syndrome.
    Journal of pediatric endocrinology & metabolism : JPEM, 2004, Volume: 17 Suppl 3

    Topics: Growth Hormone; Humans; Oxandrolone; Recombinant Proteins; Treatment Outcome; Turner Syndrome

2004
Clinical review 48: The current status of diagnosis and therapeutic intervention in Turner's syndrome.
    The Journal of clinical endocrinology and metabolism, 1993, Volume: 77, Issue:2

    Topics: Adolescent; Adult; Aortic Coarctation; Calcium, Dietary; Carbohydrate Metabolism, Inborn Errors; Chi

1993
Growth hormone therapy in Turner syndrome. Analysis of long-term results.
    Hormone research, 1995, Volume: 44 Suppl 3

    Topics: Anabolic Agents; Body Height; Drug Combinations; Growth; Growth Hormone; Humans; Oxandrolone; Turner

1995
Long-term results of growth hormone therapy in Turner syndrome.
    Endocrine, 2001, Volume: 15, Issue:1

    Topics: Adolescent; Body Height; Child; Estrogens; Female; Human Growth Hormone; Humans; Oxandrolone; Turner

2001
[Turner's syndrome is not what it was in the past].
    Archives francaises de pediatrie, 1992, Volume: 49, Issue:3

    Topics: Adolescent; Adult; Body Height; Child; Child, Preschool; Developmental Disabilities; Drug Therapy, C

1992
Current concepts in the treatment of Turner syndrome with special reference to the treatment of short stature.
    Acta paediatrica Japonica : Overseas edition, 1992, Volume: 34, Issue:2

    Topics: Age Factors; Body Height; Child; Child, Preschool; Developmental Disabilities; Ethinyl Estradiol; Fe

1992
[Turner syndrome: a virtually certain indication for growth hormone treatment].
    Tijdschrift voor kindergeneeskunde, 1992, Volume: 60, Issue:5

    Topics: Age Determination by Skeleton; Body Height; Child; Dose-Response Relationship, Drug; Drug Therapy, C

1992
[Turner's syndrome: a revolution].
    Archives francaises de pediatrie, 1992, Volume: 49, Issue:3

    Topics: Adolescent; Adult; Body Height; Child; Child, Preschool; Drug Therapy, Combination; Estrogens; Femal

1992
Growth hormone therapy in Turner's syndrome.
    Irish medical journal, 1992, Volume: 85, Issue:2

    Topics: Body Height; Drug Therapy, Combination; Female; Growth Hormone; Humans; Oxandrolone; Turner Syndrome

1992
Treatment of growth hormone insufficiency.
    Developmental pharmacology and therapeutics, 1990, Volume: 15, Issue:3-4

    Topics: Child; Child, Preschool; Chorionic Gonadotropin; Growth Disorders; Humans; Infant; Noonan Syndrome;

1990
What is the value of growth hormone treatment in short children with specified syndrome? Turner's syndrome, osteochondrodysplasias, Prader-Willi syndrome, Noonan syndrome.
    Acta paediatrica Scandinavica. Supplement, 1989, Volume: 362

    Topics: Adolescent; Adult; Child; Child, Preschool; Clinical Trials as Topic; Drug Therapy, Combination; Est

1989
[The current treatment concept of Turner syndrome].
    Padiatrie und Padologie, 1989, Volume: 24, Issue:1

    Topics: Adolescent; Body Height; Child; Drug Therapy, Combination; Estradiol; Ethinyl Estradiol; Female; Gro

1989
Anabolic steroids in girls with Turner's syndrome.
    Acta paediatrica Scandinavica. Supplement, 1988, Volume: 343

    Topics: Adolescent; Age Determination by Skeleton; Body Height; Child; Child, Preschool; Female; Humans; Oxa

1988
Treatment of short stature and delayed adolescence.
    Pediatric clinics of North America, 1987, Volume: 34, Issue:4

    Topics: Adolescent; Body Height; Child; Female; Growth Disorders; Growth Hormone; Humans; Male; Oxandrolone;

1987

Trials

38 trials available for oxandrolone and Turner Syndrome

ArticleYear
Effect of oxandrolone and timing of pubertal induction on final height in Turner syndrome: final analysis of the UK randomised placebo-controlled trial.
    Archives of disease in childhood, 2021, Volume: 106, Issue:1

    Topics: Anabolic Agents; Body Height; Child; Drug Administration Schedule; Female; Humans; Male; Oxandrolone

2021
Effect of oxandrolone and timing of oral ethinylestradiol initiation on pubertal progression, height velocity and bone maturation in the UK Turner study.
    Hormone research in paediatrics, 2014, Volume: 81, Issue:5

    Topics: Administration, Oral; Adolescent; Androgens; Estrogens; Ethinyl Estradiol; Female; Humans; Oxandrolo

2014
Karyotype-specific ear and hearing problems in young adults with Turner syndrome and the effect of oxandrolone treatment.
    Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology, 2014, Volume: 35, Issue:9

    Topics: Adolescent; Adult; Anabolic Agents; Double-Blind Method; Drug Therapy, Combination; Female; Follow-U

2014
Long-term effects of oxandrolone treatment in childhood on neurocognition, quality of life and social-emotional functioning in young adults with Turner syndrome.
    Hormones and behavior, 2015, Volume: 69

    Topics: Adolescent; Adult; Androgens; Cognition; Depression; Emotional Intelligence; Emotions; Estrogens; Fe

2015
Effects of treatment with oxandrolone for 4 years on the frequency of severe arithmetic learning disability in girls with Turner syndrome.
    The Journal of pediatrics, 2009, Volume: 155, Issue:5

    Topics: Adolescent; Androgens; Child; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administra

2009
The effect of the weak androgen oxandrolone on psychological and behavioral characteristics in growth hormone-treated girls with Turner syndrome.
    Hormones and behavior, 2010, Volume: 57, Issue:3

    Topics: Adolescent; Affect; Aggression; Androgens; Child; Child, Preschool; Double-Blind Method; Drug Therap

2010
Efficacy and safety of oxandrolone in growth hormone-treated girls with turner syndrome.
    The Journal of clinical endocrinology and metabolism, 2010, Volume: 95, Issue:3

    Topics: Adolescent; Age Factors; Androgens; Blood Pressure; Body Height; Chi-Square Distribution; Child; Chi

2010
The effect of oxandrolone on body proportions and body composition in growth hormone-treated girls with Turner syndrome.
    Clinical endocrinology, 2010, Volume: 73, Issue:2

    Topics: Adolescent; Algorithms; Androgens; Body Composition; Body Size; Child; Child, Preschool; Double-Blin

2010
Prospective study confirms oxandrolone-associated improvement in height in growth hormone-treated adolescent girls with Turner syndrome.
    Hormone research in paediatrics, 2011, Volume: 75, Issue:1

    Topics: Adolescent; Adolescent Development; Androgens; Body Height; Bone Density; Child; Child Development;

2011
Effect of oxandrolone on glucose metabolism in growth hormone-treated girls with Turner syndrome.
    Hormone research in paediatrics, 2011, Volume: 75, Issue:2

    Topics: Carbohydrate Metabolism; Child; Estrogens; Fasting; Female; Glucose; Glycated Hemoglobin; Human Grow

2011
The effect of oxandrolone on voice frequency in growth hormone-treated girls with Turner syndrome.
    Journal of voice : official journal of the Voice Foundation, 2011, Volume: 25, Issue:5

    Topics: Adolescent; Anabolic Agents; Child; Child, Preschool; Dose-Response Relationship, Drug; Estrogens; F

2011
Effect of oxandrolone and timing of pubertal induction on final height in Turner's syndrome: randomised, double blind, placebo controlled trial.
    BMJ (Clinical research ed.), 2011, Apr-14, Volume: 342

    Topics: Adolescent; Anabolic Agents; Body Height; Child; Double-Blind Method; Female; Growth Disorders; Huma

2011
[Final height (FH) in Turner syndrome (TS): experience of 76 cases followed at the Pediatric Endocrinology Unit, Hospital de Clinicas, Federal University of Paraná].
    Arquivos brasileiros de endocrinologia e metabologia, 2011, Volume: 55, Issue:5

    Topics: Adolescent; Age Determination by Skeleton; Androgens; Body Height; Child; Child, Preschool; Estrogen

2011
Androgen-responsive aspects of cognition in girls with Turner syndrome.
    The Journal of clinical endocrinology and metabolism, 2003, Volume: 88, Issue:1

    Topics: Anabolic Agents; Child; Cognition; Female; Humans; Oxandrolone; Safety; Turner Syndrome

2003
[Optimizing estrogen treatment in Turner syndrome].
    Orvosi hetilap, 2003, Mar-23, Volume: 144, Issue:12

    Topics: Adolescent; Anabolic Agents; Body Height; Child; Estrogens; Female; Growth Hormone; Humans; Menarche

2003
Oxandrolone in girls with Turner's syndrome. A pair-matched controlled study up to final height.
    Acta paediatrica Scandinavica, 1984, Volume: 73, Issue:5

    Topics: Adolescent; Age Determination by Skeleton; Body Height; Child; Clinical Trials as Topic; Ethinyl Est

1984
Effect of growth hormone and oxandrolone singly and together on growth rate in girls with X chromosome abnormalities.
    The Journal of pediatrics, 1980, Volume: 96, Issue:1

    Topics: Adolescent; Age Determination by Skeleton; Body Height; Child; Drug Administration Schedule; Drug Th

1980
Treatment of patients with Ullrich-Turner syndrome with conventional doses of growth hormone and the combination with testosterone or oxandrolone: effect on growth, IGF-I and IGFBP-3 concentrations.
    European journal of pediatrics, 1995, Volume: 154, Issue:6

    Topics: Age Determination by Skeleton; Body Height; Body Weight; Carrier Proteins; Child; Drug Therapy, Comb

1995
Final height in Turner syndrome patients treated with growth hormone.
    Hormone research, 1995, Volume: 44, Issue:4

    Topics: Age Determination by Skeleton; Anabolic Agents; Body Height; Child; Chromosome Aberrations; Chromoso

1995
The influence of growth hormone monotherapy and growth hormone in combination with oxandrolone or testosterone on thyroxid hormone parameters and thyroxine binding globulin in patients with Ullrich-Turner syndrome.
    European journal of pediatrics, 1997, Volume: 156, Issue:2

    Topics: Adolescent; Adult; Anabolic Agents; Child; Drug Therapy, Combination; Female; Growth Hormone; Humans

1997
Growth promotion and Turner-specific bone age after therapy with growth hormone and in combination with oxandrolone: when should therapy be started in Turner syndrome?
    Hormone research, 1997, Volume: 47, Issue:3

    Topics: Age Determination by Skeleton; Age Factors; Anabolic Agents; Body Height; Bone and Bones; Child; Dru

1997
Final height outcome in girls with Turner syndrome treated with a combination of low dose oestrogen and oxandrolone.
    European journal of pediatrics, 1997, Volume: 156, Issue:5

    Topics: Adolescent; Anabolic Agents; Body Height; Child; Drug Therapy, Combination; Estrogens; Female; Follo

1997
Growth hormone therapy of Turner's syndrome: beneficial effect on adult height.
    The Journal of pediatrics, 1998, Volume: 132, Issue:2

    Topics: Anabolic Agents; Body Height; Child; Child, Preschool; Drug Therapy, Combination; Female; Growth Hor

1998
Gonadotrophin pulsatility in girls with the Turner syndrome: modulation by exogenous sex steroids.
    Clinical endocrinology, 1998, Volume: 49, Issue:1

    Topics: Anabolic Agents; Biomarkers; Case-Control Studies; Child; Child, Preschool; Estradiol Congeners; Eth

1998
Long-term treatment with growth hormone has no persisting effect on lipoprotein(a) in patients with Turner's syndrome.
    The Journal of clinical endocrinology and metabolism, 1999, Volume: 84, Issue:3

    Topics: Adolescent; Apolipoproteins A; Child; Drug Combinations; Female; Human Growth Hormone; Humans; Lipop

1999
Final height of patients with Turner's syndrome treated with growth hormone (GH): indications for GH therapy alone at high doses and late estrogen therapy. Italian Study Group for Turner Syndrome.
    The Journal of clinical endocrinology and metabolism, 1999, Volume: 84, Issue:12

    Topics: Adolescent; Body Height; Child; Ethinyl Estradiol; Female; Human Growth Hormone; Humans; Karyotyping

1999
Prediction of long-term response to recombinant human growth hormone in Turner syndrome: development and validation of mathematical models. KIGS International Board. Kabi International Growth Study.
    The Journal of clinical endocrinology and metabolism, 2000, Volume: 85, Issue:11

    Topics: Anabolic Agents; Body Height; Child; Cohort Studies; Databases as Topic; Female; Growth; Human Growt

2000
Favorable final height outcome in girls with Ullrich-Turner syndrome treated with low-dose growth hormone together with oxandrolone despite starting treatment after 10 years of age.
    Journal of pediatric endocrinology & metabolism : JPEM, 2002, Volume: 15, Issue:2

    Topics: Adolescent; Age Determination by Skeleton; Aging; Anabolic Agents; Body Height; Child; Cholesterol;

2002
Growth hormone therapy in Turner's syndrome: an update on final height. Genentech National Cooperative Study Group.
    Acta paediatrica (Oslo, Norway : 1992). Supplement, 1992, Volume: 383

    Topics: Age Determination by Skeleton; Body Height; Child; Child, Preschool; Drug Therapy, Combination; Fema

1992
Recombinant human growth hormone and oxandrolone in treatment of short stature in girls with Turner syndrome.
    Hormone research, 1992, Volume: 37 Suppl 2

    Topics: Aging; Body Height; Body Weight; Bone Development; Child; Female; Growth Disorders; Growth Hormone;

1992
Six-year results of a randomized, prospective trial of human growth hormone and oxandrolone in Turner syndrome.
    The Journal of pediatrics, 1992, Volume: 121, Issue:1

    Topics: Age Determination by Skeleton; Body Height; Child; Child, Preschool; Drug Combinations; Female; Grow

1992
Three-year results of treatment with growth hormone, alone or associated with oxandrolone, in girls with Turner syndrome. The Kabi Collaborative Study Group.
    Hormone research, 1991, Volume: 35, Issue:6

    Topics: Adolescent; Body Height; Child; Female; Growth Hormone; Humans; Oxandrolone; Turner Syndrome

1991
Non-conventional growth hormone therapy in Turner syndrome: the United States experience.
    Hormone research, 1990, Volume: 33, Issue:2-4

    Topics: Body Height; Child; Child, Preschool; Drug Therapy, Combination; Female; Growth; Growth Hormone; Hum

1990
Oxandrolone increases final height in Turner syndrome.
    Journal of paediatrics and child health, 1990, Volume: 26, Issue:4

    Topics: Adolescent; Age Factors; Body Height; Child; Drug Evaluation; Ethinyl Estradiol; Female; Humans; Oxa

1990
Acceleration of growth in Turner syndrome patients treated with growth hormone: summary of three-year results.
    Journal of endocrinological investigation, 1989, Volume: 12, Issue:8 Suppl 3

    Topics: Body Height; Child; Child, Preschool; Drug Combinations; Female; Growth; Growth Hormone; Humans; Met

1989
Results from the first 2 years of a clinical trial with recombinant DNA-derived human growth hormone (somatrem) in Turner's syndrome.
    Acta paediatrica Scandinavica. Supplement, 1987, Volume: 331

    Topics: Age Determination by Skeleton; Child; Child, Preschool; Clinical Trials as Topic; Drug Therapy, Comb

1987
Three-year results of a randomized prospective trial of methionyl human growth hormone and oxandrolone in Turner syndrome.
    The Journal of pediatrics, 1988, Volume: 113, Issue:2

    Topics: Body Height; Child; Child, Preschool; Drug Therapy, Combination; Female; Growth; Growth Hormone; Hor

1988
Methionyl human growth hormone and oxandrolone in Turner syndrome: preliminary results of a prospective randomized trial.
    The Journal of pediatrics, 1986, Volume: 109, Issue:6

    Topics: Adolescent; Adult; Age Determination by Skeleton; Body Height; Child; Child, Preschool; Clinical Tri

1986

Other Studies

43 other studies available for oxandrolone and Turner Syndrome

ArticleYear
Turner syndrome: From birth to adulthood.
    Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion, 2015, Volume: 62, Issue:10

    Topics: Adolescent; Adult; Cardiovascular Diseases; Child; Child, Preschool; Delayed Diagnosis; Dwarfism; Fe

2015
SITAR--a useful instrument for growth curve analysis.
    International journal of epidemiology, 2010, Volume: 39, Issue:6

    Topics: Adolescent; Age Distribution; Body Height; Child; Cohort Studies; Female; Growth Charts; Humans; Ins

2010
Comments on 'Prospective study confirms oxandrolone-associated improvement in height in growth hormone-treated adolescent girls with Turner syndrome' by Zeger et al., pp. 39-47, this issue.
    Hormone research in paediatrics, 2011, Volume: 75, Issue:1

    Topics: Adolescent; Adolescent Development; Androgens; Body Height; Drug Monitoring; Drug Therapy, Combinati

2011
Growth hormone therapy in Turner syndrome.
    Pediatric endocrinology reviews : PER, 2012, Volume: 9 Suppl 2

    Topics: Anabolic Agents; Body Height; Child; Drug Therapy, Combination; Estrogens; Female; Growth Hormone; H

2012
Long-term effects of previous oxandrolone treatment in adult women with Turner syndrome.
    European journal of endocrinology, 2013, Volume: 168, Issue:1

    Topics: Adult; Body Height; Breast; Child; Child, Preschool; Double-Blind Method; Female; Follow-Up Studies;

2013
Treatment outcome in Turner syndrome.
    Irish medical journal, 2004, Volume: 97, Issue:1

    Topics: Adolescent; Body Height; Body Weight; Child; Dose-Response Relationship, Drug; Drug Administration S

2004
[Study of bone mass in Turner syndrome].
    Anales de pediatria (Barcelona, Spain : 2003), 2005, Volume: 62, Issue:5

    Topics: Adolescent; Anabolic Agents; Bone Density; Bone Diseases, Metabolic; Child; Child, Preschool; Estrog

2005
[Carbohydrate metabolism in patients with Turner syndrome. The effect of therapy with growth hormone, oxandrolone and a combination of both].
    Endokrynologia, diabetologia i choroby przemiany materii wieku rozwojowego : organ Polskiego Towarzystwa Endokrynologow Dzieciecych, 2005, Volume: 11, Issue:2

    Topics: Adolescent; Anabolic Agents; Blood Glucose; Carbohydrate Metabolism; Child; Child, Preschool; Diabet

2005
Metacarpophalangeal pattern profile analysis as a tool for early diagnosis of Turner syndrome.
    Acta radiologica (Stockholm, Sweden : 1987), 2005, Volume: 46, Issue:4

    Topics: Adolescent; Adult; Anabolic Agents; Child; Child, Preschool; Cohort Studies; Discriminant Analysis;

2005
Influence of X chromosome and hormones on human brain development: a magnetic resonance imaging and proton magnetic resonance spectroscopy study of Turner syndrome.
    Biological psychiatry, 2006, Feb-01, Volume: 59, Issue:3

    Topics: Adult; Aspartic Acid; Brain; Choline; Chromosomes, Human, X; Female; Gonadal Steroid Hormones; Human

2006
Hormonal therapy in a patient with a delayed diagnosis of Turner's syndrome.
    Nature clinical practice. Endocrinology & metabolism, 2008, Volume: 4, Issue:3

    Topics: Adolescent; Body Height; Estrogens; Female; Human Growth Hormone; Humans; Oxandrolone; Turner Syndro

2008
Turner syndrome: searching for better outcomes.
    Clinics (Sao Paulo, Brazil), 2008, Volume: 63, Issue:2

    Topics: Anabolic Agents; Body Height; Child; Cohort Studies; Estrogen Replacement Therapy; Female; Follow-Up

2008
[Improvement in the longitudinal growth in Ullrich-Turner syndrome with oxandrolone. Function of urinary excretion of steroid hormones].
    Deutsche medizinische Wochenschrift (1946), 1982, Jul-02, Volume: 107, Issue:26

    Topics: Adolescent; Adrenal Cortex Hormones; Age Determination by Skeleton; Androsterone; Body Height; Child

1982
[Therapy of Turner's syndrome with oxandrolone].
    Medicinski pregled, 1983, Volume: 36, Issue:9-10

    Topics: Adolescent; Child; Female; Growth Disorders; Humans; Male; Oxandrolone; Turner Syndrome

1983
Use of oxandrolone in Turner syndrome.
    The Journal of pediatrics, 1980, Volume: 96, Issue:1

    Topics: Adult; Body Height; Child; Estrogens; Female; Humans; Oxandrolone; Turner Syndrome

1980
Treatment of short stature in Turner syndrome.
    The Journal of pediatrics, 1980, Volume: 96, Issue:1

    Topics: Adolescent; Age Determination by Skeleton; Body Height; Child; Female; Growth; Humans; Oxandrolone;

1980
Short stature.
    Current therapy in endocrinology and metabolism, 1994, Volume: 5

    Topics: Adolescent; Child; Cushing Syndrome; Female; Growth Disorders; Growth Hormone; Humans; Hypothyroidis

1994
Adult height in Turner syndrome: results of a multinational survey 1993.
    Hormone research, 1994, Volume: 42, Issue:3

    Topics: Adolescent; Adult; Body Height; Estrogens; Europe; Female; Health Surveys; Humans; Japan; Middle Age

1994
Change in speaking fundamental frequency in hormone-treated patients with Turner's syndrome--a longitudinal study of four cases.
    Acta paediatrica (Oslo, Norway : 1992), 1994, Volume: 83, Issue:4

    Topics: Adolescent; Child; Drug Therapy, Combination; Ethinyl Estradiol; Female; Growth Hormone; Humans; Lon

1994
Combined therapy with growth hormone and oxandrolone in adolescent girls with Turner syndrome.
    Journal of paediatrics and child health, 1993, Volume: 29, Issue:1

    Topics: Adolescent; Age Determination by Skeleton; Body Height; Bone Development; Child; Drug Therapy, Combi

1993
Insulin, insulin-like growth factor-binding protein-1, and sex hormone-binding globulin in patients with Turner's syndrome: course over age in untreated patients and effect of therapy with growth hormone alone and in combination with oxandrolone.
    The Journal of clinical endocrinology and metabolism, 1996, Volume: 81, Issue:2

    Topics: Adolescent; Aging; Child; Child, Preschool; Cross-Sectional Studies; Female; Growth Hormone; Humans;

1996
Improved final height in girls with Turner's syndrome treated with growth hormone and oxandrolone.
    The Journal of clinical endocrinology and metabolism, 1996, Volume: 81, Issue:2

    Topics: Adolescent; Age Determination by Skeleton; Anabolic Agents; Body Height; Child; Ethinyl Estradiol; F

1996
Growth hormone in combination with anabolic steroids in patients with Turner syndrome: effect on bone maturation and final height.
    Acta paediatrica (Oslo, Norway : 1992), 1996, Volume: 85, Issue:12

    Topics: Age Determination by Skeleton; Anabolic Agents; Body Height; Child; Ethinyl Estradiol; Female; Growt

1996
Turner's syndrome, anorexia nervosa, and anabolic steroids.
    Archives of disease in childhood, 1998, Volume: 79, Issue:1

    Topics: Anabolic Agents; Anorexia Nervosa; Child; Drug Therapy, Combination; Estrogens; Female; Humans; Oxan

1998
Turner syndrome.
    European journal of endocrinology, 1999, Volume: 141, Issue:3

    Topics: Adolescent; Age Factors; Anabolic Agents; Body Height; Child; Drug Therapy, Combination; Female; Hum

1999
Blood pressure and Turner syndrome.
    Clinical endocrinology, 2000, Volume: 52, Issue:3

    Topics: Adolescent; Adult; Anabolic Agents; Analysis of Variance; Blood Pressure Monitoring, Ambulatory; Chi

2000
The influence of renal and cardiovascular abnormalities on blood pressure in Turner syndrome.
    Clinical endocrinology, 2000, Volume: 52, Issue:3

    Topics: Adolescent; Adult; Anabolic Agents; Analysis of Variance; Blood Pressure Monitoring, Ambulatory; Chi

2000
Effect of growth hormone and oxandrolone treatment on glucose metabolism in Turner syndrome. A longitudinal study.
    Hormone research, 2000, Volume: 53, Issue:1

    Topics: Adolescent; Adult; Anabolic Agents; Blood Glucose; Child; Diabetes Mellitus; Drug Therapy, Combinati

2000
Lack of correlation between gonadotropin and adrenal androgen levels in agonadal children.
    The Journal of clinical endocrinology and metabolism, 1975, Volume: 40, Issue:4

    Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Androgens; Dehydroepiandrosterone; Estrogens, Conjugated (

1975
Studies of anabolic steroids. VI. Effect of prolonged administration of oxandrolone on growth in children and adolescents with gonadal dysgenesis.
    The Journal of pediatrics, 1977, Volume: 90, Issue:3

    Topics: Age Determination by Skeleton; Body Height; Child; Female; Gonads; Growth; Humans; Oxandrolone; Turn

1977
Oxandrolone therapy in patients with Turner syndrome.
    The Journal of pediatrics, 1979, Volume: 94, Issue:5

    Topics: Body Height; Bone and Bones; Drug Administration Schedule; Drug Therapy, Combination; Fluoxymesteron

1979
Management of children with Turner's syndrome.
    Progress in clinical and biological research, 1979, Volume: 34

    Topics: Adolescent; Child; Estrogens; Female; Growth Disorders; Heart Defects, Congenital; Humans; Keloid; O

1979
Oxandrolone therapy for children with Turner syndrome.
    The Journal of pediatrics, 1977, Volume: 91, Issue:5

    Topics: Body Height; Bone Development; Child; Female; Humans; Oxandrolone; Turner Syndrome

1977
[Treatment of Turner syndrome].
    Anales espanoles de pediatria, 1992, Volume: 36 Suppl 50

    Topics: Adolescent; Body Height; Child; Estrogens; Female; Growth; Growth Hormone; Humans; Oxandrolone; Turn

1992
Growth hormone treatment in Turner's syndrome: short and long-term effects on metabolic parameters.
    Clinical endocrinology, 1992, Volume: 36, Issue:3

    Topics: Adolescent; Bone Development; Child; Drug Therapy, Combination; Ethinyl Estradiol; Fatty Acids, None

1992
[The effects of treatment with growth hormone alone or in combination with oxandrolone in a group of Turner's syndrome children. A preliminary study].
    Minerva pediatrica, 1991, Volume: 43, Issue:6

    Topics: Adolescent; Body Height; Child; Drug Evaluation; Drug Therapy, Combination; Female; Growth Hormone;

1991
Growth hormone secretion in Turner's syndrome and influence of oxandrolone and ethinyl oestradiol.
    Archives of disease in childhood, 1989, Volume: 64, Issue:4

    Topics: Body Height; Child; Child, Preschool; Ethinyl Estradiol; Female; Growth Hormone; Humans; Insulin-Lik

1989
Effect of recombinant human growth hormone therapy on bone and clinical parameters in girls with Turner's syndrome. The Spanish Collaborative Group.
    Acta paediatrica Scandinavica. Supplement, 1989, Volume: 356

    Topics: Adolescent; Bone Development; Child; Child, Preschool; Drug Therapy, Combination; Ethinyl Estradiol;

1989
Treatment of Turner's syndrome with recombinant human growth hormone (somatrem).
    Acta paediatrica Scandinavica. Supplement, 1988, Volume: 343

    Topics: Body Height; Child; Child, Preschool; Drug Therapy, Combination; Female; Glucose; Growth Hormone; Hu

1988
Carbohydrate and lipid metabolism in Turner syndrome: effect of therapy with growth hormone, oxandrolone, and a combination of both.
    The Journal of pediatrics, 1988, Volume: 112, Issue:2

    Topics: Blood Glucose; Carbohydrate Metabolism; Child; Child, Preschool; Drug Therapy, Combination; Female;

1988
Normal and abnormal sexual maturation.
    American family physician, 1974, Volume: 9, Issue:6

    Topics: Adolescent; Adrenal Gland Diseases; Age Determination by Skeleton; Bone Development; Breast; Central

1974
Oxandrolone for growth promotion in Turner syndrome.
    American journal of diseases of children (1960), 1973, Volume: 125, Issue:3

    Topics: Adolescent; Body Height; Body Weight; Bone and Bones; Child; Female; Growth; Humans; Osteogenesis; O

1973
Letter: Oxandrolone for growth stimulation.
    American journal of diseases of children (1960), 1974, Volume: 127, Issue:5

    Topics: Body Height; Female; Growth Disorders; Humans; Male; Oxandrolone; Turner Syndrome

1974