oxandrolone has been researched along with Spinal Cord Injuries in 4 studies
Oxandrolone: A synthetic hormone with anabolic and androgenic properties.
Spinal Cord Injuries: Penetrating and non-penetrating injuries to the spinal cord resulting from traumatic external forces (e.g., WOUNDS, GUNSHOT; WHIPLASH INJURIES; etc.).
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine whether oxandrolone increases the percentage of target pressure ulcers (TPUs) that heal compared with placebo and whether healed ulcers remain closed 8 weeks after treatment." | 9.17 | The effect of oxandrolone on the healing of chronic pressure ulcers in persons with spinal cord injury: a randomized trial. ( Bauman, WA; Chua, WC; Collins, JF; Deitrick, GA; Goetz, LL; Ho, C; Holmes, SA; Jayawardena, V; Merritt, JL; Nasar, F; Nemchausky, BA; Park, JS; Punj, V; Raisch, DW; Sabharwal, S; Sandford, P; Sasaki, R; Schwartz, M; Spungen, AM; Thomas, MD; Trincher, RC; Zachow, KF, 2013) |
| "To determine whether oxandrolone increases the percentage of target pressure ulcers (TPUs) that heal compared with placebo and whether healed ulcers remain closed 8 weeks after treatment." | 5.17 | The effect of oxandrolone on the healing of chronic pressure ulcers in persons with spinal cord injury: a randomized trial. ( Bauman, WA; Chua, WC; Collins, JF; Deitrick, GA; Goetz, LL; Ho, C; Holmes, SA; Jayawardena, V; Merritt, JL; Nasar, F; Nemchausky, BA; Park, JS; Punj, V; Raisch, DW; Sabharwal, S; Sandford, P; Sasaki, R; Schwartz, M; Spungen, AM; Thomas, MD; Trincher, RC; Zachow, KF, 2013) |
| "Oxandrolone is an androgenic steroid with potential neuroprotective properties that is used to prevent muscle loss and is not immunosuppressive." | 1.35 | Improved functional recovery with oxandrolone after spinal cord injury in rats. ( Bauman, WA; Cardozo, CP; Etlinger, JD; Ouyang, N; Wen, X; Zeman, RJ, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bauman, WA | 2 |
| Spungen, AM | 1 |
| Collins, JF | 1 |
| Raisch, DW | 1 |
| Ho, C | 1 |
| Deitrick, GA | 1 |
| Nemchausky, BA | 1 |
| Goetz, LL | 1 |
| Park, JS | 1 |
| Schwartz, M | 1 |
| Merritt, JL | 1 |
| Jayawardena, V | 1 |
| Sandford, P | 1 |
| Sabharwal, S | 1 |
| Holmes, SA | 1 |
| Nasar, F | 1 |
| Sasaki, R | 1 |
| Punj, V | 1 |
| Zachow, KF | 1 |
| Chua, WC | 1 |
| Thomas, MD | 1 |
| Trincher, RC | 1 |
| Zeman, RJ | 1 |
| Wen, X | 1 |
| Ouyang, N | 1 |
| Etlinger, JD | 1 |
| Cardozo, CP | 1 |
| Dickerman, RD | 1 |
| Joseph, AM | 1 |
| Bennett, MT | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| CSP #535 - Anabolic Steroid Therapy on Pressure Ulcer Healing in Persons With Spinal Cord Injury[NCT00101361] | Phase 3 | 212 participants (Actual) | Interventional | 2005-08-31 | Terminated (stopped due to futility analysis showed low probability of detecting a significant difference) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Patients remained in treatment until full healing of the target pressure ulcer (defined as re-epithelialization to a cicatrix with a dry surface and zero open area for a minimum of 96 hours) or 24 weeks, whichever occured first. (NCT00101361)
Timeframe: healing was measured from randomization to full healing or 24 weeks, whichever occured first.
| Intervention | participants (Number) |
|---|---|
| 1 Oxandrolone | 26 |
| 2 Placebo | 31 |
1 trial available for oxandrolone and Spinal Cord Injuries
| Article | Year |
|---|---|
The effect of oxandrolone on the healing of chronic pressure ulcers in persons with spinal cord injury: a randomized trial.
Topics: Aged; Anabolic Agents; Female; Humans; Liver; Male; Middle Aged; Oxandrolone; Prealbumin; Pressure U | 2013 |
3 other studies available for oxandrolone and Spinal Cord Injuries
| Article | Year |
|---|---|
Summaries for patients. Oxandrolone treatment for pressure ulcers.
Topics: Aged; Anabolic Agents; Female; Humans; Male; Middle Aged; Oxandrolone; Pressure Ulcer; Spinal Cord I | 2013 |
Improved functional recovery with oxandrolone after spinal cord injury in rats.
Topics: Anabolic Agents; Animals; Disease Models, Animal; Growth Cones; Male; Nerve Fibers, Myelinated; Nerv | 2009 |
Corticosteroid-induced myopathy in spinal cord injury patients: a role for anticatabolic agents?
Topics: Anabolic Agents; Anti-Inflammatory Agents; Drug Interactions; Humans; Methylprednisolone; Muscle, Sk | 2006 |