oxandrolone has been researched along with Pressure Ulcer in 7 studies
Oxandrolone: A synthetic hormone with anabolic and androgenic properties.
Pressure Ulcer: An ulceration caused by prolonged pressure on the SKIN and TISSUES when one stays in one position for a long period of time, such as lying in bed. The bony areas of the body are the most frequently affected sites which become ischemic (ISCHEMIA) under sustained and constant pressure.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine whether oxandrolone increases the percentage of target pressure ulcers (TPUs) that heal compared with placebo and whether healed ulcers remain closed 8 weeks after treatment." | 9.17 | The effect of oxandrolone on the healing of chronic pressure ulcers in persons with spinal cord injury: a randomized trial. ( Bauman, WA; Chua, WC; Collins, JF; Deitrick, GA; Goetz, LL; Ho, C; Holmes, SA; Jayawardena, V; Merritt, JL; Nasar, F; Nemchausky, BA; Park, JS; Punj, V; Raisch, DW; Sabharwal, S; Sandford, P; Sasaki, R; Schwartz, M; Spungen, AM; Thomas, MD; Trincher, RC; Zachow, KF, 2013) |
| "To determine whether oxandrolone increases the percentage of target pressure ulcers (TPUs) that heal compared with placebo and whether healed ulcers remain closed 8 weeks after treatment." | 5.17 | The effect of oxandrolone on the healing of chronic pressure ulcers in persons with spinal cord injury: a randomized trial. ( Bauman, WA; Chua, WC; Collins, JF; Deitrick, GA; Goetz, LL; Ho, C; Holmes, SA; Jayawardena, V; Merritt, JL; Nasar, F; Nemchausky, BA; Park, JS; Punj, V; Raisch, DW; Sabharwal, S; Sandford, P; Sasaki, R; Schwartz, M; Spungen, AM; Thomas, MD; Trincher, RC; Zachow, KF, 2013) |
| "A case of pressure ulcer in a 25-year-old male patient with the neurodegenerative disorder giant axonal neuropathy (GAN) was safely and effectively treated with an eight-week regimen of oxandrolone and nutritional supplementation." | 3.76 | Success of oxandrelone in the treatment of decubitus ulcers. ( Forman, SB; Madden, KB; Stampas, A, 2010) |
| "Pressure ulcers, also known as bed sores, pressure sores or decubitus ulcers develop as a result of a localised injury to the skin or underlying tissue, or both." | 2.55 | Anabolic steroids for treating pressure ulcers. ( Naing, C; Whittaker, MA, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 6 (85.71) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Naing, C | 1 |
| Whittaker, MA | 1 |
| Bauman, WA | 1 |
| Spungen, AM | 1 |
| Collins, JF | 1 |
| Raisch, DW | 1 |
| Ho, C | 1 |
| Deitrick, GA | 1 |
| Nemchausky, BA | 1 |
| Goetz, LL | 1 |
| Park, JS | 1 |
| Schwartz, M | 1 |
| Merritt, JL | 1 |
| Jayawardena, V | 1 |
| Sandford, P | 1 |
| Sabharwal, S | 1 |
| Holmes, SA | 1 |
| Nasar, F | 1 |
| Sasaki, R | 1 |
| Punj, V | 1 |
| Zachow, KF | 1 |
| Chua, WC | 1 |
| Thomas, MD | 1 |
| Trincher, RC | 1 |
| Salcido, R | 1 |
| Madden, KB | 1 |
| Stampas, A | 1 |
| Forman, SB | 1 |
| Mikulin, L | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| CSP #535 - Anabolic Steroid Therapy on Pressure Ulcer Healing in Persons With Spinal Cord Injury[NCT00101361] | Phase 3 | 212 participants (Actual) | Interventional | 2005-08-31 | Terminated (stopped due to futility analysis showed low probability of detecting a significant difference) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Patients remained in treatment until full healing of the target pressure ulcer (defined as re-epithelialization to a cicatrix with a dry surface and zero open area for a minimum of 96 hours) or 24 weeks, whichever occured first. (NCT00101361)
Timeframe: healing was measured from randomization to full healing or 24 weeks, whichever occured first.
| Intervention | participants (Number) |
|---|---|
| 1 Oxandrolone | 26 |
| 2 Placebo | 31 |
1 review available for oxandrolone and Pressure Ulcer
| Article | Year |
|---|---|
Anabolic steroids for treating pressure ulcers.
Topics: Female; Humans; Male; Middle Aged; Off-Label Use; Oxandrolone; Pressure Ulcer; Starch; Stearic Acids | 2017 |
1 trial available for oxandrolone and Pressure Ulcer
| Article | Year |
|---|---|
The effect of oxandrolone on the healing of chronic pressure ulcers in persons with spinal cord injury: a randomized trial.
Topics: Aged; Anabolic Agents; Female; Humans; Liver; Male; Middle Aged; Oxandrolone; Prealbumin; Pressure U | 2013 |
5 other studies available for oxandrolone and Pressure Ulcer
| Article | Year |
|---|---|
Oxandrolone no better than placebo for severe pressure ulcers.
Topics: Anabolic Agents; Female; Humans; Male; Oxandrolone; Placebo Effect; Pressure Ulcer; Treatment Outcom | 2013 |
Summaries for patients. Oxandrolone treatment for pressure ulcers.
Topics: Aged; Anabolic Agents; Female; Humans; Male; Middle Aged; Oxandrolone; Pressure Ulcer; Spinal Cord I | 2013 |
The use of off-labeled drugs in wound healing: oxandrolone.
Topics: Androgens; Humans; Off-Label Use; Oxandrolone; Pressure Ulcer; Wound Healing | 2015 |
Success of oxandrelone in the treatment of decubitus ulcers.
Topics: Adult; Anabolic Agents; Humans; Male; Oxandrolone; Pressure Ulcer | 2010 |
Nutrition and its role in wound healing.
Topics: Adult; Anabolic Agents; Enteral Nutrition; Female; HIV Wasting Syndrome; Humans; Myelitis; Nutrition | 2001 |