oxandrolone has been researched along with Fanconi Anemia in 2 studies
Oxandrolone: A synthetic hormone with anabolic and androgenic properties.
Fanconi Anemia: Congenital disorder affecting all bone marrow elements, resulting in ANEMIA; LEUKOPENIA; and THROMBOPENIA, and associated with cardiac, renal, and limb malformations as well as dermal pigmentary changes. Spontaneous CHROMOSOME BREAKAGE is a feature of this disease along with predisposition to LEUKEMIA. There are at least 7 complementation groups in Fanconi anemia: FANCA, FANCB, FANCC, FANCD1, FANCD2, FANCE, FANCF, FANCG, and FANCL. (from Online Mendelian Inheritance in Man, http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=227650, August 20, 2004)
| Excerpt | Relevance | Reference |
|---|---|---|
| " In this study we aimed to evaluate the toxicity profile and hematologic response in patients with FA who are treated with low-dose oxandrolone, a synthetic non-fluorinated anabolic steroid, similar to oxymetholone, with known dosing thresholds for virilization." | 6.79 | Oxandrolone for the treatment of bone marrow failure in Fanconi anemia. ( Bollepalli, S; Eyal, O; Harris, R; Jeng, MR; Kim, MO; Korbee, L; Ris, MD; Rose, SR; Sherafat-Kazemzadeh, R; Smith, FO; Williams, DA; Wilson, KA, 2014) |
| " In this study we aimed to evaluate the toxicity profile and hematologic response in patients with FA who are treated with low-dose oxandrolone, a synthetic non-fluorinated anabolic steroid, similar to oxymetholone, with known dosing thresholds for virilization." | 2.79 | Oxandrolone for the treatment of bone marrow failure in Fanconi anemia. ( Bollepalli, S; Eyal, O; Harris, R; Jeng, MR; Kim, MO; Korbee, L; Ris, MD; Rose, SR; Sherafat-Kazemzadeh, R; Smith, FO; Williams, DA; Wilson, KA, 2014) |
| "3 of the 4 patients had bilateral cryptorchidism, 2 with increased plasma gonadotrophins, indicating primary testicular failure." | 1.26 | Endocrine studies in Fanconi's anaemia. Report of 4 cases. ( Aynsley-Green, A; Illig, R; Prader, A; Werder, EA; Zachmann, M, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rose, SR | 1 |
| Kim, MO | 1 |
| Korbee, L | 1 |
| Wilson, KA | 1 |
| Ris, MD | 1 |
| Eyal, O | 1 |
| Sherafat-Kazemzadeh, R | 1 |
| Bollepalli, S | 1 |
| Harris, R | 1 |
| Jeng, MR | 1 |
| Williams, DA | 1 |
| Smith, FO | 1 |
| Aynsley-Green, A | 1 |
| Zachmann, M | 1 |
| Werder, EA | 1 |
| Illig, R | 1 |
| Prader, A | 1 |
1 trial available for oxandrolone and Fanconi Anemia
| Article | Year |
|---|---|
Oxandrolone for the treatment of bone marrow failure in Fanconi anemia.
Topics: Anabolic Agents; Anemia, Aplastic; Bone Marrow Diseases; Bone Marrow Failure Disorders; Child; Fanco | 2014 |
1 other study available for oxandrolone and Fanconi Anemia
| Article | Year |
|---|---|
Endocrine studies in Fanconi's anaemia. Report of 4 cases.
Topics: Anemia, Aplastic; Child; Child, Preschool; Cryptorchidism; Dwarfism; Fanconi Anemia; Growth Hormone; | 1978 |